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The map label for this gene is asd [H]

Identifier: 23099065

GI number: 23099065

Start: 1647985

End: 1649037

Strand: Direct

Name: asd [H]

Synonym: OB1610

Alternate gene names: 23099065

Gene position: 1647985-1649037 (Clockwise)

Preceding gene: 23099064

Following gene: 23099066

Centisome position: 45.39

GC content: 37.13

Gene sequence:

>1053_bases
ATGACACAGGAAACAAAGTATAACGTGGCAGTAGTTGGCGCGACAGGCGCTGTAGGACAAAAAATCATCGAACTATTACA
AGGCAAATCATTCCCAATTAACAATTTAAAATTACTCTCGTCAAAACGTTCAGCTGGTTCTGCTGTTACAGTGAATGGCA
AAGAAATTATTGTAGAAGAAGCTACACCCGAATCTTTTGAAGGAGTAGATATTGCTCTATTTTCTGCTGGTGGATCTGTC
TCGAAGCAACTTGCTCCTGAAGCAGTAAAAAGGGGTGCGGTAGTTGTAGATAATACAAGTGCTTACCGTATGGATCCAGA
TGTACCTTTAGTTGTTCCGGAAGTAAATCCGGAAGATTTAAAAAATCATCAAGGAATTATCGCAAATCCTAACTGCTCTA
CGATTCAAATGGTAGCTGCATTACAACCTATCAAAGAAAAGTATGGCTTAAATAAAGTTATTGTTTCTACCTATCAGGCA
GTGTCTGGTGCAGGAAATGAAGCAATTGATGAATTAAAGACACAATCACAGCAACAACTTAATGGCGAAGCATTAGAAGC
AAATTTACTCCCTGTTAAAGGTGATGAAAAACATTATCCGATTGCTTTTAATGCTTTACCACAAATTGATGTTTTCCAAG
AAAATGGGTATACATTTGAAGAAATGAAAATGATTAATGAAACGAAGAAAATCTTACATGATGATGCATTACATGTAGCA
GCAACGTGTGTACGTCTTCCATTTGTTACTTCACATGCAGAGAGTGTGTATGTAGAATTAGAAGAAGCTGGTGTACAAGT
AAAAGATATTTGGAATTTACTAGAATCCGCAGATGGAATTATCTTAGAAGATGATCCAACCAATCAGACATACCCTACTC
CGCTATCAGCTGAAGGGAAAGAAGAGGTCTTTGTTGGTCGTGTGCGTAAAGATTTAGATGAGGATAAAGGATTCCATCTC
TGGGTAGTATCTGATAACCTATTAAAAGGGGCAGCTTGGAATACAGTCCAAATTGCACAAACTTTAATTGAGAAAGATTG
GTTAAAAAAATAA

Upstream 100 bases:

>100_bases
GGGAAACAACTTCAGCCGATAATTGTACCTTATCAAGAGTAAAGTATGTTAGAATAGTTTACTAGAGAACAGAATTAGAA
TGTGGAAGGGAGTCATTTTA

Downstream 100 bases:

>100_bases
CCCAATACAAAAATACAATCATCCAATAGTCAAACTTGGATAGCTTATAGAGGTGTTTTAAAGTGCAAGTGATGGTCCAA
AAATTTGGAGGAACTTCGGT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTQETKYNVAVVGATGAVGQKIIELLQGKSFPINNLKLLSSKRSAGSAVTVNGKEIIVEEATPESFEGVDIALFSAGGSV
SKQLAPEAVKRGAVVVDNTSAYRMDPDVPLVVPEVNPEDLKNHQGIIANPNCSTIQMVAALQPIKEKYGLNKVIVSTYQA
VSGAGNEAIDELKTQSQQQLNGEALEANLLPVKGDEKHYPIAFNALPQIDVFQENGYTFEEMKMINETKKILHDDALHVA
ATCVRLPFVTSHAESVYVELEEAGVQVKDIWNLLESADGIILEDDPTNQTYPTPLSAEGKEEVFVGRVRKDLDEDKGFHL
WVVSDNLLKGAAWNTVQIAQTLIEKDWLKK

Sequences:

>Translated_350_residues
MTQETKYNVAVVGATGAVGQKIIELLQGKSFPINNLKLLSSKRSAGSAVTVNGKEIIVEEATPESFEGVDIALFSAGGSV
SKQLAPEAVKRGAVVVDNTSAYRMDPDVPLVVPEVNPEDLKNHQGIIANPNCSTIQMVAALQPIKEKYGLNKVIVSTYQA
VSGAGNEAIDELKTQSQQQLNGEALEANLLPVKGDEKHYPIAFNALPQIDVFQENGYTFEEMKMINETKKILHDDALHVA
ATCVRLPFVTSHAESVYVELEEAGVQVKDIWNLLESADGIILEDDPTNQTYPTPLSAEGKEEVFVGRVRKDLDEDKGFHL
WVVSDNLLKGAAWNTVQIAQTLIEKDWLKK
>Mature_349_residues
TQETKYNVAVVGATGAVGQKIIELLQGKSFPINNLKLLSSKRSAGSAVTVNGKEIIVEEATPESFEGVDIALFSAGGSVS
KQLAPEAVKRGAVVVDNTSAYRMDPDVPLVVPEVNPEDLKNHQGIIANPNCSTIQMVAALQPIKEKYGLNKVIVSTYQAV
SGAGNEAIDELKTQSQQQLNGEALEANLLPVKGDEKHYPIAFNALPQIDVFQENGYTFEEMKMINETKKILHDDALHVAA
TCVRLPFVTSHAESVYVELEEAGVQVKDIWNLLESADGIILEDDPTNQTYPTPLSAEGKEEVFVGRVRKDLDEDKGFHLW
VVSDNLLKGAAWNTVQIAQTLIEKDWLKK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=347, Percent_Identity=32.8530259365994, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=25.7703081232493, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320362, Length=396, Percent_Identity=29.2929292929293, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38194; Mature: 38062

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQETKYNVAVVGATGAVGQKIIELLQGKSFPINNLKLLSSKRSAGSAVTVNGKEIIVEE
CCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEECCCEEEEEC
ATPESFEGVDIALFSAGGSVSKQLAPEAVKRGAVVVDNTSAYRMDPDVPLVVPEVNPEDL
CCCCCCCCCEEEEEECCCCCHHHCCHHHHHCCEEEEECCCCEEECCCCCEEECCCCHHHH
KNHQGIIANPNCSTIQMVAALQPIKEKYGLNKVIVSTYQAVSGAGNEAIDELKTQSQQQL
HCCCCEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
NGEALEANLLPVKGDEKHYPIAFNALPQIDVFQENGYTFEEMKMINETKKILHDDALHVA
CCCEEEEEEEECCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ATCVRLPFVTSHAESVYVELEEAGVQVKDIWNLLESADGIILEDDPTNQTYPTPLSAEGK
HHHHHCCCEECCCCEEEEEEHHHCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCC
EEVFVGRVRKDLDEDKGFHLWVVSDNLLKGAAWNTVQIAQTLIEKDWLKK
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQETKYNVAVVGATGAVGQKIIELLQGKSFPINNLKLLSSKRSAGSAVTVNGKEIIVEE
CCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEECCCEEEEEC
ATPESFEGVDIALFSAGGSVSKQLAPEAVKRGAVVVDNTSAYRMDPDVPLVVPEVNPEDL
CCCCCCCCCEEEEEECCCCCHHHCCHHHHHCCEEEEECCCCEEECCCCCEEECCCCHHHH
KNHQGIIANPNCSTIQMVAALQPIKEKYGLNKVIVSTYQAVSGAGNEAIDELKTQSQQQL
HCCCCEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
NGEALEANLLPVKGDEKHYPIAFNALPQIDVFQENGYTFEEMKMINETKKILHDDALHVA
CCCEEEEEEEECCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ATCVRLPFVTSHAESVYVELEEAGVQVKDIWNLLESADGIILEDDPTNQTYPTPLSAEGK
HHHHHCCCEECCCCEEEEEEHHHCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCC
EEVFVGRVRKDLDEDKGFHLWVVSDNLLKGAAWNTVQIAQTLIEKDWLKK
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]