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The map label for this gene is ctaD [H]

Identifier: 23098893

GI number: 23098893

Start: 1478522

End: 1480375

Strand: Direct

Name: ctaD [H]

Synonym: OB1438

Alternate gene names: 23098893

Gene position: 1478522-1480375 (Clockwise)

Preceding gene: 23098892

Following gene: 23098894

Centisome position: 40.72

GC content: 38.62

Gene sequence:

>1854_bases
TTGAGTGTTAACAGTGCTCACAAGAGTGGTTTTGGTGCTACTTTATGGGATTGGCTAACTACCGTTGATCATAAAAAAAT
CGGTATTTTGTATCTCGCAGCAGGTGCATTTTTCTTCCTGCTAGGTGGACTAGAAGCACTTATCATACGAATTCAGTTAA
TTTCACCACAAAATGATTTCATTAGTGCTGGATTGTATAATGAAATGATTACCATGCATGGTACAACCATGATATTCTTT
GCGGCAACGCCGTTACTCTTTGGATTAATGAACTATATTATGCCATTACAAATTGGGGCACGTGATGTAGCGTTCCCATT
CTTGAACTCTTTAGGTTTTTGGCTATTCTTCTTCGGAGGAATAATGTTGAATTTAAGTTGGTTTACTGGTGCTCCAGATG
CCGGTTGGACAAACTATGCTCCACTTTCCTTACAATCACCTGGGCATGGGGTGGATTTCTATGTAATGGGATTACAGTTA
TCTGGTGCTGGGACGTTAATGAGTGGTATTAACTTCATCGTTACGATCGTACTTATGCGTGCGCCAGGAATGACATATAT
GCGAATGCCACTATTTACTTGGACGACATTTGTAACAAGTATCTTAGTATTATTTGCATTTCCAGCTTTAACAGTTGGAC
TATTCTTAATGATGTTTGATCGTATGTTCGGTACAGCATTCTTTGATGTTGCACTAGGTGGTAACTCCATTATCTGGCAA
CATTTATTCTGGATTTTTGGACACCCTGAGGTATATATCTTAATACTACCTGCATTTGGTGTGTTTAGTGAAATATTACC
TACATTTTCAAAGAAGCGTTTATTTGGATATACGGCAATGGTATTTGCTACATTCTTAATCGCTTTCTTAGGATTTATGG
TTTGGGCTCACCATATGTTTACGGTAGGACTTGGCCCCGTTGCTAACTCTATATTTGCAGTTGCAACAATGGCGATTGCT
GTTCCAACTGGTATTAAGATATTTAACTGGCTGTTCACGCTATGGGGTGGAAGTATTACAATCAATTCCGCTATGTTATG
GACACTTGCGTTCATACCATCATTTACAATTGGTGGAATGACTGGTGTAATGCTTGCTTCTTCAGTAGCTGACTATCAAT
ACCACGATAGTTACTTCGTAGTTGGTCATTTCCACTATGTTATTGTTGGTGGTGTAGTATTTGCTTTACTTGCTGCAATG
CATTATTGGTGGCCAAAGATGTTCGGACGCTATCTACATGAAGGCATGGGTAAATTAGCATTCTGGACATTCTTTATAGG
ATTCCATTTAACATTCTTTATTCAGCATTTCTTAGGTTTAATGGGTATGCCACGTCGTTATTGGGTATTCTTAGAAGACC
AAGGTTTGGATGCAGGAAACTTAATAAGTACTATTGGTGCTTTCTTTATGACATTTGGGGTATTAGTATTTGTTATAAAT
ATTTTCTACACGTGGAAGAAGGGTGAAAAAGCTCCTGGTGATGCTTGGGGTACTGGTAGAACTCTGGAATGGGCAACTGC
TTCACCACCTATCCACTTCAATTTTAAACAAATGCCACTTGTTCGTGGTTTAGATCCACTTTGGATTGAGAAGATGGAAG
GGAATAATAAAATGACTCCGGCTGAGCCAATGGATGAAATTCATATGCCAAACGGATCTATTCTCCCACTTATTATGACA
ATCGGCTTCTTTATTGCATCCTATGGATTTATATATCAAGTTGACCATAAAGCTTGGTTAATTGCGGTATATGTAGGAAT
GGCAATTGGTATGGGTTGTATGTTAATTCGTTCTTTAAGAGACGATCACGGTTATCATATCTCTAAAGAAGAAGTAGAAA
GGGAGGGTGATTGA

Upstream 100 bases:

>100_bases
ATTGCAGAATACTTATTACAATTACAGCCTTCAGAAATTACTCCTGAAAGTGCTGGCAATTAAGACTTGGGATGGAAGAC
ATGAAAGGGAGGTATAAGCA

Downstream 100 bases:

>100_bases
TATGAGTCATCATGATCATTCCATTGACCCGAAGAATCTAACACAAGACCCTTCAAAAGCAACGATGGAAGGAAAGCATA
AGTTTCTTGGTTTGTGGATA

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MSVNSAHKSGFGATLWDWLTTVDHKKIGILYLAAGAFFFLLGGLEALIIRIQLISPQNDFISAGLYNEMITMHGTTMIFF
AATPLLFGLMNYIMPLQIGARDVAFPFLNSLGFWLFFFGGIMLNLSWFTGAPDAGWTNYAPLSLQSPGHGVDFYVMGLQL
SGAGTLMSGINFIVTIVLMRAPGMTYMRMPLFTWTTFVTSILVLFAFPALTVGLFLMMFDRMFGTAFFDVALGGNSIIWQ
HLFWIFGHPEVYILILPAFGVFSEILPTFSKKRLFGYTAMVFATFLIAFLGFMVWAHHMFTVGLGPVANSIFAVATMAIA
VPTGIKIFNWLFTLWGGSITINSAMLWTLAFIPSFTIGGMTGVMLASSVADYQYHDSYFVVGHFHYVIVGGVVFALLAAM
HYWWPKMFGRYLHEGMGKLAFWTFFIGFHLTFFIQHFLGLMGMPRRYWVFLEDQGLDAGNLISTIGAFFMTFGVLVFVIN
IFYTWKKGEKAPGDAWGTGRTLEWATASPPIHFNFKQMPLVRGLDPLWIEKMEGNNKMTPAEPMDEIHMPNGSILPLIMT
IGFFIASYGFIYQVDHKAWLIAVYVGMAIGMGCMLIRSLRDDHGYHISKEEVEREGD

Sequences:

>Translated_617_residues
MSVNSAHKSGFGATLWDWLTTVDHKKIGILYLAAGAFFFLLGGLEALIIRIQLISPQNDFISAGLYNEMITMHGTTMIFF
AATPLLFGLMNYIMPLQIGARDVAFPFLNSLGFWLFFFGGIMLNLSWFTGAPDAGWTNYAPLSLQSPGHGVDFYVMGLQL
SGAGTLMSGINFIVTIVLMRAPGMTYMRMPLFTWTTFVTSILVLFAFPALTVGLFLMMFDRMFGTAFFDVALGGNSIIWQ
HLFWIFGHPEVYILILPAFGVFSEILPTFSKKRLFGYTAMVFATFLIAFLGFMVWAHHMFTVGLGPVANSIFAVATMAIA
VPTGIKIFNWLFTLWGGSITINSAMLWTLAFIPSFTIGGMTGVMLASSVADYQYHDSYFVVGHFHYVIVGGVVFALLAAM
HYWWPKMFGRYLHEGMGKLAFWTFFIGFHLTFFIQHFLGLMGMPRRYWVFLEDQGLDAGNLISTIGAFFMTFGVLVFVIN
IFYTWKKGEKAPGDAWGTGRTLEWATASPPIHFNFKQMPLVRGLDPLWIEKMEGNNKMTPAEPMDEIHMPNGSILPLIMT
IGFFIASYGFIYQVDHKAWLIAVYVGMAIGMGCMLIRSLRDDHGYHISKEEVEREGD
>Mature_616_residues
SVNSAHKSGFGATLWDWLTTVDHKKIGILYLAAGAFFFLLGGLEALIIRIQLISPQNDFISAGLYNEMITMHGTTMIFFA
ATPLLFGLMNYIMPLQIGARDVAFPFLNSLGFWLFFFGGIMLNLSWFTGAPDAGWTNYAPLSLQSPGHGVDFYVMGLQLS
GAGTLMSGINFIVTIVLMRAPGMTYMRMPLFTWTTFVTSILVLFAFPALTVGLFLMMFDRMFGTAFFDVALGGNSIIWQH
LFWIFGHPEVYILILPAFGVFSEILPTFSKKRLFGYTAMVFATFLIAFLGFMVWAHHMFTVGLGPVANSIFAVATMAIAV
PTGIKIFNWLFTLWGGSITINSAMLWTLAFIPSFTIGGMTGVMLASSVADYQYHDSYFVVGHFHYVIVGGVVFALLAAMH
YWWPKMFGRYLHEGMGKLAFWTFFIGFHLTFFIQHFLGLMGMPRRYWVFLEDQGLDAGNLISTIGAFFMTFGVLVFVINI
FYTWKKGEKAPGDAWGTGRTLEWATASPPIHFNFKQMPLVRGLDPLWIEKMEGNNKMTPAEPMDEIHMPNGSILPLIMTI
GFFIASYGFIYQVDHKAWLIAVYVGMAIGMGCMLIRSLRDDHGYHISKEEVEREGD

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=505, Percent_Identity=43.1683168316832, Blast_Score=367, Evalue=1e-101,
Organism=Escherichia coli, GI1786634, Length=614, Percent_Identity=46.4169381107492, Blast_Score=509, Evalue=1e-145,
Organism=Saccharomyces cerevisiae, GI6226519, Length=467, Percent_Identity=43.254817987152, Blast_Score=372, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6226524, Length=320, Percent_Identity=44.0625, Blast_Score=257, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6226523, Length=244, Percent_Identity=36.8852459016393, Blast_Score=147, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 69174; Mature: 69042

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNSAHKSGFGATLWDWLTTVDHKKIGILYLAAGAFFFLLGGLEALIIRIQLISPQNDF
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHEEHHHHHHHHHHHHHHHHHEEEEEECCCCCH
ISAGLYNEMITMHGTTMIFFAATPLLFGLMNYIMPLQIGARDVAFPFLNSLGFWLFFFGG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IMLNLSWFTGAPDAGWTNYAPLSLQSPGHGVDFYVMGLQLSGAGTLMSGINFIVTIVLMR
HHEEEEEECCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHH
APGMTYMRMPLFTWTTFVTSILVLFAFPALTVGLFLMMFDRMFGTAFFDVALGGNSIIWQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHH
HLFWIFGHPEVYILILPAFGVFSEILPTFSKKRLFGYTAMVFATFLIAFLGFMVWAHHMF
HHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVGLGPVANSIFAVATMAIAVPTGIKIFNWLFTLWGGSITINSAMLWTLAFIPSFTIGGM
HHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCCCCH
TGVMLASSVADYQYHDSYFVVGHFHYVIVGGVVFALLAAMHYWWPKMFGRYLHEGMGKLA
HHHHHHHHHHCCEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWTFFIGFHLTFFIQHFLGLMGMPRRYWVFLEDQGLDAGNLISTIGAFFMTFGVLVFVIN
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
IFYTWKKGEKAPGDAWGTGRTLEWATASPPIHFNFKQMPLVRGLDPLWIEKMEGNNKMTP
HHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCHHHCCCHHHHEEECCCCCCCC
AEPMDEIHMPNGSILPLIMTIGFFIASYGFIYQVDHKAWLIAVYVGMAIGMGCMLIRSLR
CCCHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
DDHGYHISKEEVEREGD
CCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
SVNSAHKSGFGATLWDWLTTVDHKKIGILYLAAGAFFFLLGGLEALIIRIQLISPQNDF
CCCCCCCCCCCHHHHHHHHHCCCCCHHHEEHHHHHHHHHHHHHHHHHEEEEEECCCCCH
ISAGLYNEMITMHGTTMIFFAATPLLFGLMNYIMPLQIGARDVAFPFLNSLGFWLFFFGG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IMLNLSWFTGAPDAGWTNYAPLSLQSPGHGVDFYVMGLQLSGAGTLMSGINFIVTIVLMR
HHEEEEEECCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHH
APGMTYMRMPLFTWTTFVTSILVLFAFPALTVGLFLMMFDRMFGTAFFDVALGGNSIIWQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHH
HLFWIFGHPEVYILILPAFGVFSEILPTFSKKRLFGYTAMVFATFLIAFLGFMVWAHHMF
HHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVGLGPVANSIFAVATMAIAVPTGIKIFNWLFTLWGGSITINSAMLWTLAFIPSFTIGGM
HHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCCCCH
TGVMLASSVADYQYHDSYFVVGHFHYVIVGGVVFALLAAMHYWWPKMFGRYLHEGMGKLA
HHHHHHHHHHCCEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWTFFIGFHLTFFIQHFLGLMGMPRRYWVFLEDQGLDAGNLISTIGAFFMTFGVLVFVIN
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
IFYTWKKGEKAPGDAWGTGRTLEWATASPPIHFNFKQMPLVRGLDPLWIEKMEGNNKMTP
HHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCHHHCCCHHHHEEECCCCCCCC
AEPMDEIHMPNGSILPLIMTIGFFIASYGFIYQVDHKAWLIAVYVGMAIGMGCMLIRSLR
CCCHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
DDHGYHISKEEVEREGD
CCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]