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The map label for this gene is paiA [H]

Identifier: 23098702

GI number: 23098702

Start: 1294644

End: 1295162

Strand: Direct

Name: paiA [H]

Synonym: OB1247

Alternate gene names: 23098702

Gene position: 1294644-1295162 (Clockwise)

Preceding gene: 23098701

Following gene: 23098703

Centisome position: 35.66

GC content: 34.49

Gene sequence:

>519_bases
ATGAGTATAAATATGACTAGATGTACCTTAGAAGATTCACGACAACTTCAATATATTGGGTATAAAACATTTAAGGAGAC
ATTTGAGGATCAGAATTCGCCAGAAAATATGAAGGTCTATTTGGAACAGGCTTTTAACATAAATCAAATAGAAAGGGAGT
TATCCAATACTTCATCGCATTTCTTTTTTGTTTCTTTTAATGATGAGGTAGCTGGATATTTAAAGGTTAATACCGGGGAT
GCCCAGACTGAAGAAATGGATGATGACGCCCTTGAAATCGAACGGATTTATATTATTAATAAATTTCAAAAGCTTGGGCT
TGGTAAATATTTGTTCAATAAAGCTATGGATATTGCAATGGCACAAAATAAAAAGAAGATTTGGCTGGGAGTGTGGGAAA
AAAATGAAAATGCCATTTCTTTTTACAAGAGAGTGGGTTTTACTCAAACGGGAGCGCACTCTTTTTATATGGGGGATGAA
GAACAAACGGACTTGATAATGGTTAAAGAGCTCGAATAG

Upstream 100 bases:

>100_bases
CTTCTTCAAAGAGTAAGAAAAAATATAGAAAAAGACTGGGAACTCGTAAAAAAAGGAAACAAGAGAAGTTATTAATAGTA
GAAAGGAGTGAAAGGTCTAA

Downstream 100 bases:

>100_bases
CAGTTCATGTAATTTGGAATGACAAAAAACATAGGTAGAAAATGAGCAAACTTTTTAATGAAAATTGTATAGTGTTTCAT
AAAAAATGAATCCGTTTTGA

Product: transcriptional repressor of sporulation, septation and degradation

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSINMTRCTLEDSRQLQYIGYKTFKETFEDQNSPENMKVYLEQAFNINQIERELSNTSSHFFFVSFNDEVAGYLKVNTGD
AQTEEMDDDALEIERIYIINKFQKLGLGKYLFNKAMDIAMAQNKKKIWLGVWEKNENAISFYKRVGFTQTGAHSFYMGDE
EQTDLIMVKELE

Sequences:

>Translated_172_residues
MSINMTRCTLEDSRQLQYIGYKTFKETFEDQNSPENMKVYLEQAFNINQIERELSNTSSHFFFVSFNDEVAGYLKVNTGD
AQTEEMDDDALEIERIYIINKFQKLGLGKYLFNKAMDIAMAQNKKKIWLGVWEKNENAISFYKRVGFTQTGAHSFYMGDE
EQTDLIMVKELE
>Mature_171_residues
SINMTRCTLEDSRQLQYIGYKTFKETFEDQNSPENMKVYLEQAFNINQIERELSNTSSHFFFVSFNDEVAGYLKVNTGDA
QTEEMDDDALEIERIYIINKFQKLGLGKYLFNKAMDIAMAQNKKKIWLGVWEKNENAISFYKRVGFTQTGAHSFYMGDEE
QTDLIMVKELE

Specific function: Possesses N1-acetyltransferase activity toward polyamine substrates including spermidine and spermine. Can acetylate both spermidine and spermine. In this way it may function in regulating intracellular polyamine concentrations and/or binding capabilities

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: NA

Molecular weight: Translated: 20159; Mature: 20028

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINMTRCTLEDSRQLQYIGYKTFKETFEDQNSPENMKVYLEQAFNINQIERELSNTSSH
CCCCEEEEECCCCCEEEEECHHHHHHHHHCCCCCCCEEEEEEHHCCHHHHHHHHCCCCCE
FFFVSFNDEVAGYLKVNTGDAQTEEMDDDALEIERIYIINKFQKLGLGKYLFNKAMDIAM
EEEEEECCCEEEEEEEECCCCCCCCCCCCHHEEEEEEEEEHHHHCCCCHHHHHHHHHHHC
AQNKKKIWLGVWEKNENAISFYKRVGFTQTGAHSFYMGDEEQTDLIMVKELE
CCCCCEEEEEEEECCCCHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEECC
>Mature Secondary Structure 
SINMTRCTLEDSRQLQYIGYKTFKETFEDQNSPENMKVYLEQAFNINQIERELSNTSSH
CCCEEEEECCCCCEEEEECHHHHHHHHHCCCCCCCEEEEEEHHCCHHHHHHHHCCCCCE
FFFVSFNDEVAGYLKVNTGDAQTEEMDDDALEIERIYIINKFQKLGLGKYLFNKAMDIAM
EEEEEECCCEEEEEEEECCCCCCCCCCCCHHEEEEEEEEEHHHHCCCCHHHHHHHHHHHC
AQNKKKIWLGVWEKNENAISFYKRVGFTQTGAHSFYMGDEEQTDLIMVKELE
CCCCCEEEEEEEECCCCHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2108124; 9384377 [H]