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The map label for this gene is mntH [H]

Identifier: 23098192

GI number: 23098192

Start: 784741

End: 785994

Strand: Direct

Name: mntH [H]

Synonym: OB0737

Alternate gene names: 23098192

Gene position: 784741-785994 (Clockwise)

Preceding gene: 23098191

Following gene: 23098193

Centisome position: 21.62

GC content: 35.81

Gene sequence:

>1254_bases
ATGGAAGATCCGAATCTAGAAGCAAATAGACAGGATAAGAAGTCGTTTATTCAAAAAGTGAAATCTGTTGGACCAGGTGC
AATTATTGCTGCTTCATTTATAGGGCCTGGAACGGTAACTACTTCTACACAGGCTGGAGCAAGTTTCGGTTATGCATTAA
TTTGGGCGGTTCTATTCTCCATTTTGGCAACCATTGTTTTACAAGAAATGTCTGCACGTTTAGGTATTATTTCAAAGAAA
GGATTAGCTGAAGCTGCTAGAGATCAATTTAACCATCCTGCAATAAAATATCCGATTATTGGATTCATCATTATGGCAAT
ATACGTGGGCTGTACTGCATATATGAGTGGTGATTTAAGAGGAACATCGTTAGGATTAGAGGCCTTAACAGGGGTTTCCA
TCAATATTATAGGACCAATTGTCGGAATTTTAATACTTTTACTTGGGTTAAGTGGCAGCTATAAATTGATTGAAAAATTA
ATGGTGTTCTTTGTTGTTTTAATGAGCATTATTTTTATCACTACCATGTTTATAGCTCAGCCTGATATAGGTGGAGTGTT
GTCCGGAATGTTTGTACCATCTATTCCCGTTGGTTCAATTATTACAATTATAGCATTAATAGGAACGACTGTTGTACCAT
ATAACTTATTTATCCACTCTTCATCCGTACAAGAAAGATGGTCGCGACCTGAACAATTGAAGGATTCACGAAGAGACATT
TATTTTTCCATTGGTGTTGGTGGTTTGATTACGATTGCAATCGTAATTACATCAGGAACACTGATGCGAGGAGTGGAAGT
TGGCAGTGTGATAGATTTAGCAATACAATTAGAACCTTTACTTGGTGGATTTGCGGAATCATTTTTAGCTATCGGGATTT
TTTCTGCCGGATTTTCTTCAGCTACAGCATCTGCATTAGGTGCTGCCATTACGGTAAGTAGTATGTTGAAATGGGAAAAT
GGAATGAAAAATTGGAAATTTAAAGCTGTATTCTCTTCCGTAATTATCATTGGTATCCTGTCCTTTGTATTTCGATTTGA
GCCATTAGACGTTTTATTATTCGCTCAAGCGTTAAATGGTATATTACTACCTAGTATTGCGATTTTATTAATAGTTATAA
TGAATAATAAAAAATTACTAGGAAGCTATGCAAACTCCACGATCATTAATATAATTGGAATAGTAGTTGTTGTTATTTGT
ACTGGGCTAGGGATTTACAGTCTAGTTACAGCAATACAGGGATTCATTGGATAA

Upstream 100 bases:

>100_bases
TTGAATGATAATAAGAGGGGAATCAGGTATAGAAGTATTTTATCATTCATACGTTTGAAGAAGATAAGTATTACGTATCT
AGGAAGAGGAAGGTGTAGCT

Downstream 100 bases:

>100_bases
AGATTGATATGAGCATGTCACCTGGTAGGATGGCATGTTGTCGTCCATGTATGCTAGATTAGAAAGATTACATGAATGAG
TAGAGGAGGATTTCCCGTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MEDPNLEANRQDKKSFIQKVKSVGPGAIIAASFIGPGTVTTSTQAGASFGYALIWAVLFSILATIVLQEMSARLGIISKK
GLAEAARDQFNHPAIKYPIIGFIIMAIYVGCTAYMSGDLRGTSLGLEALTGVSINIIGPIVGILILLLGLSGSYKLIEKL
MVFFVVLMSIIFITTMFIAQPDIGGVLSGMFVPSIPVGSIITIIALIGTTVVPYNLFIHSSSVQERWSRPEQLKDSRRDI
YFSIGVGGLITIAIVITSGTLMRGVEVGSVIDLAIQLEPLLGGFAESFLAIGIFSAGFSSATASALGAAITVSSMLKWEN
GMKNWKFKAVFSSVIIIGILSFVFRFEPLDVLLFAQALNGILLPSIAILLIVIMNNKKLLGSYANSTIINIIGIVVVVIC
TGLGIYSLVTAIQGFIG

Sequences:

>Translated_417_residues
MEDPNLEANRQDKKSFIQKVKSVGPGAIIAASFIGPGTVTTSTQAGASFGYALIWAVLFSILATIVLQEMSARLGIISKK
GLAEAARDQFNHPAIKYPIIGFIIMAIYVGCTAYMSGDLRGTSLGLEALTGVSINIIGPIVGILILLLGLSGSYKLIEKL
MVFFVVLMSIIFITTMFIAQPDIGGVLSGMFVPSIPVGSIITIIALIGTTVVPYNLFIHSSSVQERWSRPEQLKDSRRDI
YFSIGVGGLITIAIVITSGTLMRGVEVGSVIDLAIQLEPLLGGFAESFLAIGIFSAGFSSATASALGAAITVSSMLKWEN
GMKNWKFKAVFSSVIIIGILSFVFRFEPLDVLLFAQALNGILLPSIAILLIVIMNNKKLLGSYANSTIINIIGIVVVVIC
TGLGIYSLVTAIQGFIG
>Mature_417_residues
MEDPNLEANRQDKKSFIQKVKSVGPGAIIAASFIGPGTVTTSTQAGASFGYALIWAVLFSILATIVLQEMSARLGIISKK
GLAEAARDQFNHPAIKYPIIGFIIMAIYVGCTAYMSGDLRGTSLGLEALTGVSINIIGPIVGILILLLGLSGSYKLIEKL
MVFFVVLMSIIFITTMFIAQPDIGGVLSGMFVPSIPVGSIITIIALIGTTVVPYNLFIHSSSVQERWSRPEQLKDSRRDI
YFSIGVGGLITIAIVITSGTLMRGVEVGSVIDLAIQLEPLLGGFAESFLAIGIFSAGFSSATASALGAAITVSSMLKWEN
GMKNWKFKAVFSSVIIIGILSFVFRFEPLDVLLFAQALNGILLPSIAILLIVIMNNKKLLGSYANSTIINIIGIVVVVIC
TGLGIYSLVTAIQGFIG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=246, Percent_Identity=26.4227642276423, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1788736, Length=420, Percent_Identity=25.952380952381, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17569473, Length=379, Percent_Identity=27.7044854881267, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71993856, Length=240, Percent_Identity=29.1666666666667, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193210616, Length=221, Percent_Identity=29.8642533936652, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71999499, Length=445, Percent_Identity=23.5955056179775, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323062, Length=405, Percent_Identity=22.7160493827161, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324450, Length=238, Percent_Identity=26.890756302521, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24648607, Length=456, Percent_Identity=22.3684210526316, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281362176, Length=456, Percent_Identity=22.3684210526316, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24648609, Length=456, Percent_Identity=22.3684210526316, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45553443, Length=259, Percent_Identity=26.2548262548263, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 44237; Mature: 44237

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDPNLEANRQDKKSFIQKVKSVGPGAIIAASFIGPGTVTTSTQAGASFGYALIWAVLFS
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
ILATIVLQEMSARLGIISKKGLAEAARDQFNHPAIKYPIIGFIIMAIYVGCTAYMSGDLR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GTSLGLEALTGVSINIIGPIVGILILLLGLSGSYKLIEKLMVFFVVLMSIIFITTMFIAQ
CCHHHHHHHHCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDIGGVLSGMFVPSIPVGSIITIIALIGTTVVPYNLFIHSSSVQERWSRPEQLKDSRRDI
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCHHHHHCCCCHHHHHCCCCE
YFSIGVGGLITIAIVITSGTLMRGVEVGSVIDLAIQLEPLLGGFAESFLAIGIFSAGFSS
EEEECCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ATASALGAAITVSSMLKWENGMKNWKFKAVFSSVIIIGILSFVFRFEPLDVLLFAQALNG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
ILLPSIAILLIVIMNNKKLLGSYANSTIINIIGIVVVVICTGLGIYSLVTAIQGFIG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEDPNLEANRQDKKSFIQKVKSVGPGAIIAASFIGPGTVTTSTQAGASFGYALIWAVLFS
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
ILATIVLQEMSARLGIISKKGLAEAARDQFNHPAIKYPIIGFIIMAIYVGCTAYMSGDLR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GTSLGLEALTGVSINIIGPIVGILILLLGLSGSYKLIEKLMVFFVVLMSIIFITTMFIAQ
CCHHHHHHHHCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDIGGVLSGMFVPSIPVGSIITIIALIGTTVVPYNLFIHSSSVQERWSRPEQLKDSRRDI
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCHHHHHCCCCHHHHHCCCCE
YFSIGVGGLITIAIVITSGTLMRGVEVGSVIDLAIQLEPLLGGFAESFLAIGIFSAGFSS
EEEECCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ATASALGAAITVSSMLKWENGMKNWKFKAVFSSVIIIGILSFVFRFEPLDVLLFAQALNG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
ILLPSIAILLIVIMNNKKLLGSYANSTIINIIGIVVVVICTGLGIYSLVTAIQGFIG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA