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The map label for this gene is rhaD

Identifier: 23097952

GI number: 23097952

Start: 528632

End: 529468

Strand: Direct

Name: rhaD

Synonym: OB0497

Alternate gene names: 23097952

Gene position: 528632-529468 (Clockwise)

Preceding gene: 23097951

Following gene: 23097953

Centisome position: 14.56

GC content: 36.08

Gene sequence:

>837_bases
ATGACACAGGATATTACACAACAAGATGTGTTAGATGCACCTTTTATGAAAGAAATGATGAATACAACATATGATATGTG
GAAACTTGGATGGGATGAACTTAATGGAGGTAACATCAGCTATCTACTAAAAGAAGAAGAGGTAAGAAGTTACTTTGATT
TGAACCAAGTAAAGCGAACTATTTCATTAGATTTTCCGGTAATAGAGTTGGCAAATCAGTATTTCCTTGTTACTGGATCA
GGTAAGTTCTTCAGAAAAATTATAGAAAATCCAGAAGAATGTTTAGCGGTATTACGAGTAACTAGTGATGGAGAATCAGT
TGAACTTCTATGGGGATTAAGTGATGGAGGAAGACCGACAAGTGAGTTAGCATCTCACTTTATGAGTCATATTGTTCGAT
TAAAACATGATCCGAATCATCGAGTCATCATGCACACACATGCAACAAACTTAATTGCAATGACATTTACACATGAATTA
GATGAAGTTCAATTTACTCGGACATTATGGCAAATGTGTACAGAATGCTTAGTGGTATTCCCTGAAGGAGTAGGGATACT
CCCATGGATGGTTCCTGGAACTTCAGAAATTGGAAAGGCTACAGCGGAAAAAATGAATGAATATCGTTTAGCAATTTGGT
CACATCATGGAATATTTGGTGCAGGGGAGTCAATTGATCAAGTATTTGGATTAATTGAAACAGTGGAGAAGGCTGCAAAA
GTCTATAATCTTGTAAACGCACATCCAGACGGTGCTAAACAAGTAATTACTGATCAGCAACTGATAGATTTAGCAGAAGC
TTTTCATGTGAATCCTCCTAATAAATACTTTTCTTAA

Upstream 100 bases:

>100_bases
CAGTTGGAGAGTCATGGTTAACAGAGGTAAAAGAATATGAAAAAGAAGTTTTATCTAAGCGATAATTTTAAGAGGATTTG
AAGTGGAAAGGGAGAGAATG

Downstream 100 bases:

>100_bases
AAGGCCGATGCAATTATGAAAGAACGAAGCAGTGGAAATACAAGTGTTTCGTTCTTTCTATGCTTGTTAAACTTAGTAGA
AAATGGGTAAAATATAGTAA

Product: rhamnulose-1-phosphate aldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTQDITQQDVLDAPFMKEMMNTTYDMWKLGWDELNGGNISYLLKEEEVRSYFDLNQVKRTISLDFPVIELANQYFLVTGS
GKFFRKIIENPEECLAVLRVTSDGESVELLWGLSDGGRPTSELASHFMSHIVRLKHDPNHRVIMHTHATNLIAMTFTHEL
DEVQFTRTLWQMCTECLVVFPEGVGILPWMVPGTSEIGKATAEKMNEYRLAIWSHHGIFGAGESIDQVFGLIETVEKAAK
VYNLVNAHPDGAKQVITDQQLIDLAEAFHVNPPNKYFS

Sequences:

>Translated_278_residues
MTQDITQQDVLDAPFMKEMMNTTYDMWKLGWDELNGGNISYLLKEEEVRSYFDLNQVKRTISLDFPVIELANQYFLVTGS
GKFFRKIIENPEECLAVLRVTSDGESVELLWGLSDGGRPTSELASHFMSHIVRLKHDPNHRVIMHTHATNLIAMTFTHEL
DEVQFTRTLWQMCTECLVVFPEGVGILPWMVPGTSEIGKATAEKMNEYRLAIWSHHGIFGAGESIDQVFGLIETVEKAAK
VYNLVNAHPDGAKQVITDQQLIDLAEAFHVNPPNKYFS
>Mature_277_residues
TQDITQQDVLDAPFMKEMMNTTYDMWKLGWDELNGGNISYLLKEEEVRSYFDLNQVKRTISLDFPVIELANQYFLVTGSG
KFFRKIIENPEECLAVLRVTSDGESVELLWGLSDGGRPTSELASHFMSHIVRLKHDPNHRVIMHTHATNLIAMTFTHELD
EVQFTRTLWQMCTECLVVFPEGVGILPWMVPGTSEIGKATAEKMNEYRLAIWSHHGIFGAGESIDQVFGLIETVEKAAKV
YNLVNAHPDGAKQVITDQQLIDLAEAFHVNPPNKYFS

Specific function: Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. RhaD subfamily

Homologues:

Organism=Escherichia coli, GI1790336, Length=267, Percent_Identity=49.063670411985, Blast_Score=262, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RHAD_OCEIH (Q8ESW9)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691418.1
- ProteinModelPortal:   Q8ESW9
- SMR:   Q8ESW9
- GeneID:   1015766
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0497
- NMPDR:   fig|221109.1.peg.501
- HOGENOM:   HBG416653
- OMA:   MSHIARL
- ProtClustDB:   PRK03634
- BioCyc:   OIHE221109:OB0497-MONOMER
- BRENDA:   4.1.2.19
- GO:   GO:0005737
- HAMAP:   MF_00770
- InterPro:   IPR001303
- InterPro:   IPR013447
- Gene3D:   G3DSA:3.40.225.10
- TIGRFAMs:   TIGR02624

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: =4.1.2.19

Molecular weight: Translated: 31580; Mature: 31449

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: ACT_SITE 122-122

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDITQQDVLDAPFMKEMMNTTYDMWKLGWDELNGGNISYLLKEEEVRSYFDLNQVKRT
CCCCCCHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEEHHHHHHHHHHHHHHHH
ISLDFPVIELANQYFLVTGSGKFFRKIIENPEECLAVLRVTSDGESVELLWGLSDGGRPT
HCCCCHHHHHCCCEEEEECCCHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCH
SELASHFMSHIVRLKHDPNHRVIMHTHATNLIAMTFTHELDEVQFTRTLWQMCTECLVVF
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHEEC
PEGVGILPWMVPGTSEIGKATAEKMNEYRLAIWSHHGIFGAGESIDQVFGLIETVEKAAK
CCCCCCCCEECCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
VYNLVNAHPDGAKQVITDQQLIDLAEAFHVNPPNKYFS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure 
TQDITQQDVLDAPFMKEMMNTTYDMWKLGWDELNGGNISYLLKEEEVRSYFDLNQVKRT
CCCCCHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEEHHHHHHHHHHHHHHHH
ISLDFPVIELANQYFLVTGSGKFFRKIIENPEECLAVLRVTSDGESVELLWGLSDGGRPT
HCCCCHHHHHCCCEEEEECCCHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCH
SELASHFMSHIVRLKHDPNHRVIMHTHATNLIAMTFTHELDEVQFTRTLWQMCTECLVVF
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHEEC
PEGVGILPWMVPGTSEIGKATAEKMNEYRLAIWSHHGIFGAGESIDQVFGLIETVEKAAK
CCCCCCCCEECCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
VYNLVNAHPDGAKQVITDQQLIDLAEAFHVNPPNKYFS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376