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The map label for this gene is yjfP [C]

Identifier: 23097917

GI number: 23097917

Start: 488251

End: 490047

Strand: Direct

Name: yjfP [C]

Synonym: OB0462

Alternate gene names: 23097917

Gene position: 488251-490047 (Clockwise)

Preceding gene: 23097915

Following gene: 23097918

Centisome position: 13.45

GC content: 36.45

Gene sequence:

>1797_bases
ATGTCAAAAAAACAAGATGTAAACAAATTGTTGTCATTTTTGAATGCAAAGGGCGCATACCAACCTAGAAAAATTGGTGA
AAGTACAGATTTTACGTTTTTGGCAAATTTAACAGGAAGACCACAAGTTTGGAAGATAGATGAAAAAGGAAAAGTATCTG
CTTTTCATGAGCTGAAGGATAGAGTACTACAGGTATATCATTCTCCTTCTGGAAAGCATACCGTATTAGCTTCTGACTTT
GAAGGGAATGAAAAGCAACAGTTTTATTTAAGCTCAGATAATGGAAAGACAATAGAAGATTTAGTAATATCTCCTGAGCA
TTTTCACCAATTTGGTGGTTGGTCTCCAGATGAGAGCAAAATTACGTATGCAAGCAATCGAAGAGATCCGGGATATTTTG
ATATTTTCACATTGAATATCAAAACAAAAGAAGAAGTCACTGTGTTTGAATCCAATACAAATTGTACTCCATTAACTTGG
ACGGCAGATGGTAAAGGTATTATCTTTACGTACGCTGTTTCGAATATTGATAATCAATTACATATTTTAGACCTTGAATC
GGGGAAAACAAAGCCAATTGGTAATGTAAATGTCCCAGCTAGATACCATTCAGTTCAGTTAACGAAAGATAATTTGTCAG
GGTATGTTGTAACCGATGAAGGTAGAGATACTTTAGCAATTGCAAAGTTCCATCTTGAAAAACCAGATTCATTAGAATTT
ATCTATAAAAGTGAGCAATGGGACATTGAGGAAGTTAAGGTATCTGCTGACGAAAAGCATCTTGCTTTCTCACTAAATGA
AGGTGGAAGTTCGCAATTAGGAATCTATTCTGTAGATAAAAACAAAGTAAAATTCACTAAATCATTGCCAGTTGGAGTCT
ATCAATCTATACAATGGTTAAATGAACGAGCGTTATTAATAGGAGTAACAAGCTCGATATTGCCAGGCGATATATGGAAA
GTAGATATAGTAGAAAATGAATCAGAGCGACTAACGAATATTGGTGAAAGTCCGGAAGTTGATCATCTGTGGGTGGAACC
CGAAGTATGTCATTTTTCTTCCTTTGATGGATTAGAAGTTCCATATTTTCTATATGGAAAGAAATCAACGAACCAACCTG
TAATGATATATGTTCATGGTGGTCCTGAGAGTCAAATTCGCAATGAGTATAACCCTGTTATTCAGTATCTTGCTGCCCAA
GGATATGCCGTTGCAGCTCCTAATGTCCGTGGAAGCATGGGGTATGGGAGGGAATATGTTCAGTTAGATGATATTCGGAA
AAGAATGGATGCGGTGGCAGATTTAAATTATCTTGTAGAAGATTTAGTATCTACACATCAAACAGACAGAAATCGTGTTG
GGATCATGGGGAGAAGTTACGGTGGATTTATGGTATTAGCTGCTATTACGCATTATCCTACTGTATGGGCCGCTGCAGTA
GATATTGTAGGTATTAGCCATTTCCGGACCTTCTTAGAAAATACTGGTCCTTGGAGAAGAAGACTTCGTGAACAGGAATA
TGGTTCGTTGGAGCATGATAGTGATTTCTTTGAAGAAATAGCACCATTAAATCATACTGAAAAGATTCAAGTACCATTAC
TTATTTTCCATGGAAAGAATGATACTCGTGTACCAGTTTCAGAAGCAGAGCAGCTCACCAAAGATTTAGAGTCTCAAGGA
AAAGATGTTGAGTTAATTATTTTTGAAGATGAAGGGCATCAAACGGAAAAACTCGAAAATCATGTGGTAATGAATAAGAA
AACCGTAGAATTTATGGATCAATGGTTAGGTGAATAG

Upstream 100 bases:

>100_bases
AATTGATTTATTAGATTATTTCATCTATACTTTATTGTTATATTAATAGTTTTAAAAATACAACAAAAAATTAGAAAATT
CAACATGGAGGGATCAACAA

Downstream 100 bases:

>100_bases
CGTAATATTTTCCAATTGAAAGAAAATTCCTTCAAATATATTGCTAACCTACTGTTTTTTGTGTATATTTAAAATTAGTA
TTTTCGTCATTTTTTGACAA

Product: acylamino-acid-releasing enzyme

Products: NA

Alternate protein names: AARE; Acyl-peptide hydrolase; APH; Acylaminoacyl-peptidase [H]

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MSKKQDVNKLLSFLNAKGAYQPRKIGESTDFTFLANLTGRPQVWKIDEKGKVSAFHELKDRVLQVYHSPSGKHTVLASDF
EGNEKQQFYLSSDNGKTIEDLVISPEHFHQFGGWSPDESKITYASNRRDPGYFDIFTLNIKTKEEVTVFESNTNCTPLTW
TADGKGIIFTYAVSNIDNQLHILDLESGKTKPIGNVNVPARYHSVQLTKDNLSGYVVTDEGRDTLAIAKFHLEKPDSLEF
IYKSEQWDIEEVKVSADEKHLAFSLNEGGSSQLGIYSVDKNKVKFTKSLPVGVYQSIQWLNERALLIGVTSSILPGDIWK
VDIVENESERLTNIGESPEVDHLWVEPEVCHFSSFDGLEVPYFLYGKKSTNQPVMIYVHGGPESQIRNEYNPVIQYLAAQ
GYAVAAPNVRGSMGYGREYVQLDDIRKRMDAVADLNYLVEDLVSTHQTDRNRVGIMGRSYGGFMVLAAITHYPTVWAAAV
DIVGISHFRTFLENTGPWRRRLREQEYGSLEHDSDFFEEIAPLNHTEKIQVPLLIFHGKNDTRVPVSEAEQLTKDLESQG
KDVELIIFEDEGHQTEKLENHVVMNKKTVEFMDQWLGE

Sequences:

>Translated_598_residues
MSKKQDVNKLLSFLNAKGAYQPRKIGESTDFTFLANLTGRPQVWKIDEKGKVSAFHELKDRVLQVYHSPSGKHTVLASDF
EGNEKQQFYLSSDNGKTIEDLVISPEHFHQFGGWSPDESKITYASNRRDPGYFDIFTLNIKTKEEVTVFESNTNCTPLTW
TADGKGIIFTYAVSNIDNQLHILDLESGKTKPIGNVNVPARYHSVQLTKDNLSGYVVTDEGRDTLAIAKFHLEKPDSLEF
IYKSEQWDIEEVKVSADEKHLAFSLNEGGSSQLGIYSVDKNKVKFTKSLPVGVYQSIQWLNERALLIGVTSSILPGDIWK
VDIVENESERLTNIGESPEVDHLWVEPEVCHFSSFDGLEVPYFLYGKKSTNQPVMIYVHGGPESQIRNEYNPVIQYLAAQ
GYAVAAPNVRGSMGYGREYVQLDDIRKRMDAVADLNYLVEDLVSTHQTDRNRVGIMGRSYGGFMVLAAITHYPTVWAAAV
DIVGISHFRTFLENTGPWRRRLREQEYGSLEHDSDFFEEIAPLNHTEKIQVPLLIFHGKNDTRVPVSEAEQLTKDLESQG
KDVELIIFEDEGHQTEKLENHVVMNKKTVEFMDQWLGE
>Mature_597_residues
SKKQDVNKLLSFLNAKGAYQPRKIGESTDFTFLANLTGRPQVWKIDEKGKVSAFHELKDRVLQVYHSPSGKHTVLASDFE
GNEKQQFYLSSDNGKTIEDLVISPEHFHQFGGWSPDESKITYASNRRDPGYFDIFTLNIKTKEEVTVFESNTNCTPLTWT
ADGKGIIFTYAVSNIDNQLHILDLESGKTKPIGNVNVPARYHSVQLTKDNLSGYVVTDEGRDTLAIAKFHLEKPDSLEFI
YKSEQWDIEEVKVSADEKHLAFSLNEGGSSQLGIYSVDKNKVKFTKSLPVGVYQSIQWLNERALLIGVTSSILPGDIWKV
DIVENESERLTNIGESPEVDHLWVEPEVCHFSSFDGLEVPYFLYGKKSTNQPVMIYVHGGPESQIRNEYNPVIQYLAAQG
YAVAAPNVRGSMGYGREYVQLDDIRKRMDAVADLNYLVEDLVSTHQTDRNRVGIMGRSYGGFMVLAAITHYPTVWAAAVD
IVGISHFRTFLENTGPWRRRLREQEYGSLEHDSDFFEEIAPLNHTEKIQVPLLIFHGKNDTRVPVSEAEQLTKDLESQGK
DVELIIFEDEGHQTEKLENHVVMNKKTVEFMDQWLGE

Specific function: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N- acetylated amino acid and a peptide with a free N-terminus [H]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9C family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=219, Percent_Identity=24.2009132420091, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI194394146, Length=274, Percent_Identity=27.007299270073, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17552908, Length=242, Percent_Identity=30.1652892561983, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25144540, Length=434, Percent_Identity=25.3456221198157, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI25144537, Length=431, Percent_Identity=25.754060324826, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144543, Length=133, Percent_Identity=32.3308270676692, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564634, Length=258, Percent_Identity=25.5813953488372, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564632, Length=258, Percent_Identity=25.5813953488372, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508017, Length=302, Percent_Identity=26.8211920529801, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508019, Length=302, Percent_Identity=26.8211920529801, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45551969, Length=237, Percent_Identity=28.6919831223629, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45550825, Length=237, Percent_Identity=28.6919831223629, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45553511, Length=237, Percent_Identity=28.6919831223629, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR001375
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.4.19.1 [H]

Molecular weight: Translated: 67814; Mature: 67683

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKQDVNKLLSFLNAKGAYQPRKIGESTDFTFLANLTGRPQVWKIDEKGKVSAFHELKD
CCCHHHHHHHHHHHCCCCCCCCHHCCCCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHH
RVLQVYHSPSGKHTVLASDFEGNEKQQFYLSSDNGKTIEDLVISPEHFHQFGGWSPDESK
HHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHEECCHHHHHHHCCCCCCCCE
ITYASNRRDPGYFDIFTLNIKTKEEVTVFESNTNCTPLTWTADGKGIIFTYAVSNIDNQL
EEEECCCCCCCEEEEEEEEEECCCEEEEEECCCCCCEEEEECCCCEEEEEEEECCCCCEE
HILDLESGKTKPIGNVNVPARYHSVQLTKDNLSGYVVTDEGRDTLAIAKFHLEKPDSLEF
EEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCCEEE
IYKSEQWDIEEVKVSADEKHLAFSLNEGGSSQLGIYSVDKNKVKFTKSLPVGVYQSIQWL
EEECCCCCHHHEEECCCCCEEEEEECCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHH
NERALLIGVTSSILPGDIWKVDIVENESERLTNIGESPEVDHLWVEPEVCHFSSFDGLEV
CCCEEEEEECCCCCCCCCEEEEEEECCHHHHHCCCCCCCCCEEEECCCEECCCCCCCCCC
PYFLYGKKSTNQPVMIYVHGGPESQIRNEYNPVIQYLAAQGYAVAAPNVRGSMGYGREYV
CEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEE
QLDDIRKRMDAVADLNYLVEDLVSTHQTDRNRVGIMGRSYGGFMVLAAITHYPTVWAAAV
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEHHHHCCHHHHHHH
DIVGISHFRTFLENTGPWRRRLREQEYGSLEHDSDFFEEIAPLNHTEKIQVPLLIFHGKN
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEEEEEECCC
DTRVPVSEAEQLTKDLESQGKDVELIIFEDEGHQTEKLENHVVMNKKTVEFMDQWLGE
CCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHCCEEECCHHHHHHHHHHCC
>Mature Secondary Structure 
SKKQDVNKLLSFLNAKGAYQPRKIGESTDFTFLANLTGRPQVWKIDEKGKVSAFHELKD
CCHHHHHHHHHHHCCCCCCCCHHCCCCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHH
RVLQVYHSPSGKHTVLASDFEGNEKQQFYLSSDNGKTIEDLVISPEHFHQFGGWSPDESK
HHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHEECCHHHHHHHCCCCCCCCE
ITYASNRRDPGYFDIFTLNIKTKEEVTVFESNTNCTPLTWTADGKGIIFTYAVSNIDNQL
EEEECCCCCCCEEEEEEEEEECCCEEEEEECCCCCCEEEEECCCCEEEEEEEECCCCCEE
HILDLESGKTKPIGNVNVPARYHSVQLTKDNLSGYVVTDEGRDTLAIAKFHLEKPDSLEF
EEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCCEEE
IYKSEQWDIEEVKVSADEKHLAFSLNEGGSSQLGIYSVDKNKVKFTKSLPVGVYQSIQWL
EEECCCCCHHHEEECCCCCEEEEEECCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHH
NERALLIGVTSSILPGDIWKVDIVENESERLTNIGESPEVDHLWVEPEVCHFSSFDGLEV
CCCEEEEEECCCCCCCCCEEEEEEECCHHHHHCCCCCCCCCEEEECCCEECCCCCCCCCC
PYFLYGKKSTNQPVMIYVHGGPESQIRNEYNPVIQYLAAQGYAVAAPNVRGSMGYGREYV
CEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEE
QLDDIRKRMDAVADLNYLVEDLVSTHQTDRNRVGIMGRSYGGFMVLAAITHYPTVWAAAV
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEHHHHCCHHHHHHH
DIVGISHFRTFLENTGPWRRRLREQEYGSLEHDSDFFEEIAPLNHTEKIQVPLLIFHGKN
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEEEEEECCC
DTRVPVSEAEQLTKDLESQGKDVELIIFEDEGHQTEKLENHVVMNKKTVEFMDQWLGE
CCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHCCEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10382966; 12037315 [H]