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The map label for this gene is 229918359

Identifier: 229918359

GI number: 229918359

Start: 2610808

End: 2611440

Strand: Direct

Name: 229918359

Synonym: EAT1b_2644

Alternate gene names: NA

Gene position: 2610808-2611440 (Clockwise)

Preceding gene: 229918358

Following gene: 229918360

Centisome position: 87.03

GC content: 56.71

Gene sequence:

>633_bases
ATGACCGCTTCGCAACGGGCACGGCTCGAGGCGAGCGGTCTTTCCGTTCATCATGTCCCGCTCATTCAGACGAAAGAGAC
GCACATCCCGCCACCCGTGGAACGATTCGATTGGCTCGTCGTGACGAGTCAAAACGCGGTGCCCGCCCTTCAAAATCTGA
CGCGTGACGTCAAAGTCGCCGCTGTCGGGGAGAAGACGAAGCGGGCGCTTGAAGCGGAGGGGTTCACCGTCTCGCTCATG
CCGGAGACGTATACGGGTGAGGCACTCTTTAAGCAGTTACTCGATGTCGTGTCAACCGATGACGTCGTCTTGTTCGCGCG
TGGCAATTTGGCGAACACGTCCCATATGTCGATGTTGCCTCATGTACAGGACTGGGTCGTCTATGAGACGGTTCCAGTGC
CGTTGACACCGGCGCAACAGCAACAACTCGAAATCGTAAAGGCGTTGCTCGTCTTGAGCCCGTCGGCGGTCGAGGCGCTC
ACACCATACTTGTCCCGCTTCAACGGGACGTGGTACGCCATCGGCGAAGTGACCGAACGCGCCGTCCGACAAGTGTCGAC
GTTACCGATACGAGTGCCAGAATGTTATACTATGGATGCATTAATACAGTGTGTAGGGGAGGATTTTTCATGA

Upstream 100 bases:

>100_bases
GCACTCGGACAAGCAGTCGCAGAAGAATTGCTCGGTCGTGGCGGGCGTGAAATCCTCGCCTCGGTCAATGAGTGACGTAT
GGTACACGGGAACGAAACGA

Downstream 100 bases:

>100_bases
ACCAGTTTGACCGTCACCGTCGTCTTCGCTCATCGAAGTCGATGCGTGCCCTCGTACGTGAAAATCATGTTCGAAAAGAA
GATTTGATTTACCCGCTCTT

Product: Uroporphyrinogen III synthase HEM4

Products: uroporphyrinogen III; H2O

Alternate protein names: Uroporphyrinogen III Cosynthase

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTASQRARLEASGLSVHHVPLIQTKETHIPPPVERFDWLVVTSQNAVPALQNLTRDVKVAAVGEKTKRALEAEGFTVSLM
PETYTGEALFKQLLDVVSTDDVVLFARGNLANTSHMSMLPHVQDWVVYETVPVPLTPAQQQQLEIVKALLVLSPSAVEAL
TPYLSRFNGTWYAIGEVTERAVRQVSTLPIRVPECYTMDALIQCVGEDFS

Sequences:

>Translated_210_residues
MTASQRARLEASGLSVHHVPLIQTKETHIPPPVERFDWLVVTSQNAVPALQNLTRDVKVAAVGEKTKRALEAEGFTVSLM
PETYTGEALFKQLLDVVSTDDVVLFARGNLANTSHMSMLPHVQDWVVYETVPVPLTPAQQQQLEIVKALLVLSPSAVEAL
TPYLSRFNGTWYAIGEVTERAVRQVSTLPIRVPECYTMDALIQCVGEDFS
>Mature_209_residues
TASQRARLEASGLSVHHVPLIQTKETHIPPPVERFDWLVVTSQNAVPALQNLTRDVKVAAVGEKTKRALEAEGFTVSLMP
ETYTGEALFKQLLDVVSTDDVVLFARGNLANTSHMSMLPHVQDWVVYETVPVPLTPAQQQQLEIVKALLVLSPSAVEALT
PYLSRFNGTWYAIGEVTERAVRQVSTLPIRVPECYTMDALIQCVGEDFS

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 23197; Mature: 23066

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASQRARLEASGLSVHHVPLIQTKETHIPPPVERFDWLVVTSQNAVPALQNLTRDVKVA
CCCCCCCEEEECCCEEEEEEEEECCCCCCCCCHHHCEEEEEECCCCCHHHHHHHHHEEEE
AVGEKTKRALEAEGFTVSLMPETYTGEALFKQLLDVVSTDDVVLFARGNLANTSHMSMLP
EECHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCC
HVQDWVVYETVPVPLTPAQQQQLEIVKALLVLSPSAVEALTPYLSRFNGTWYAIGEVTER
CCHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEHHHHHHH
AVRQVSTLPIRVPECYTMDALIQCVGEDFS
HHHHHHCCCEECCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TASQRARLEASGLSVHHVPLIQTKETHIPPPVERFDWLVVTSQNAVPALQNLTRDVKVA
CCCCCCEEEECCCEEEEEEEEECCCCCCCCCHHHCEEEEEECCCCCHHHHHHHHHEEEE
AVGEKTKRALEAEGFTVSLMPETYTGEALFKQLLDVVSTDDVVLFARGNLANTSHMSMLP
EECHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCC
HVQDWVVYETVPVPLTPAQQQQLEIVKALLVLSPSAVEALTPYLSRFNGTWYAIGEVTER
CCHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEHHHHHHH
AVRQVSTLPIRVPECYTMDALIQCVGEDFS
HHHHHHCCCEECCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA