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The map label for this gene is yggV [C]

Identifier: 229918349

GI number: 229918349

Start: 2598893

End: 2599483

Strand: Direct

Name: yggV [C]

Synonym: EAT1b_2634

Alternate gene names: 229918349

Gene position: 2598893-2599483 (Clockwise)

Preceding gene: 229918348

Following gene: 229918350

Centisome position: 86.63

GC content: 53.13

Gene sequence:

>591_bases
ATGAAGTTGATCATTGCGACACACAATCCTGGAAAAGTGAAAGAACTCGAAGGGATGTTGACGCCGCTCGGATTCGAGGT
CGAGTCACTCCTCGACTATCCGGATGCGCCAGAGACGGATGAGACCGGCACGACGTTTGAAGAGAATGCGGCGTTAAAAG
CGACGGAGGCGGCAGCTTACTTTGGGCATGCCGTCCTCGCGGATGACTCCGGTCTTGAAGTCGACGCGCTTGACGGGGCA
CCGGGAGTATACTCGGCCCGTTTTGCAGGTCCAGAAAAGTCAGACGAGGCGAACAACGCTCTTCTTCTTGAAAAATTGAA
CGGAGAGACGAATCGTACGGCTCGTTTCGTCTGTGCGCTCTGCCTTGCGAAACCGAGCGGAGAGACGTTGACCGTTCGTG
GAACAATCGAAGGGACAATCGGTTATTCCCCACAAGGTGAAAATGGTTTTGGATACGATCCACTCTTTATCGTCCCATCG
CTTCATAAGACAGCGGCAGAATTGGAACGTGACGAGAAGGCGGTCGTCAGCCACCGTGGACAGGCACTACGAAAACTGGA
GGCAGAAATCATACCATTCATGAAAGGATGA

Upstream 100 bases:

>100_bases
TCGCACTCGCGCAACACGGCATCGAATCATTATTCAAGACGGCGGAAGCGGCACTCGGTGCTTCTTGGTGGTACGTCGGG
GAACGTTCGGAGGAGACATT

Downstream 100 bases:

>100_bases
AGCTTATGCGTTTTCTAATAGTGAGTGATAGTCATGGGTTGACCGAAGAGTTGACGACGATTTTTGAACGACACGAGGCG
GAAATCGATGACGCGTTCCA

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKLIIATHNPGKVKELEGMLTPLGFEVESLLDYPDAPETDETGTTFEENAALKATEAAAYFGHAVLADDSGLEVDALDGA
PGVYSARFAGPEKSDEANNALLLEKLNGETNRTARFVCALCLAKPSGETLTVRGTIEGTIGYSPQGENGFGYDPLFIVPS
LHKTAAELERDEKAVVSHRGQALRKLEAEIIPFMKG

Sequences:

>Translated_196_residues
MKLIIATHNPGKVKELEGMLTPLGFEVESLLDYPDAPETDETGTTFEENAALKATEAAAYFGHAVLADDSGLEVDALDGA
PGVYSARFAGPEKSDEANNALLLEKLNGETNRTARFVCALCLAKPSGETLTVRGTIEGTIGYSPQGENGFGYDPLFIVPS
LHKTAAELERDEKAVVSHRGQALRKLEAEIIPFMKG
>Mature_196_residues
MKLIIATHNPGKVKELEGMLTPLGFEVESLLDYPDAPETDETGTTFEENAALKATEAAAYFGHAVLADDSGLEVDALDGA
PGVYSARFAGPEKSDEANNALLLEKLNGETNRTARFVCALCLAKPSGETLTVRGTIEGTIGYSPQGENGFGYDPLFIVPS
LHKTAAELERDEKAVVSHRGQALRKLEAEIIPFMKG

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=189, Percent_Identity=46.031746031746, Blast_Score=154, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6322529, Length=201, Percent_Identity=28.8557213930348, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19920712, Length=182, Percent_Identity=32.4175824175824, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_EXISA (C4L4I7)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002886995.1
- ProteinModelPortal:   C4L4I7
- GeneID:   7869646
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2634
- OMA:   TGVTFAE
- ProtClustDB:   PRK14822
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 20953; Mature: 20953

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIIATHNPGKVKELEGMLTPLGFEVESLLDYPDAPETDETGTTFEENAALKATEAAAY
CEEEEEECCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHH
FGHAVLADDSGLEVDALDGAPGVYSARFAGPEKSDEANNALLLEKLNGETNRTARFVCAL
HCEEEEECCCCCEEEECCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHH
CLAKPSGETLTVRGTIEGTIGYSPQGENGFGYDPLFIVPSLHKTAAELERDEKAVVSHRG
HHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
QALRKLEAEIIPFMKG
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKLIIATHNPGKVKELEGMLTPLGFEVESLLDYPDAPETDETGTTFEENAALKATEAAAY
CEEEEEECCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHH
FGHAVLADDSGLEVDALDGAPGVYSARFAGPEKSDEANNALLLEKLNGETNRTARFVCAL
HCEEEEECCCCCEEEECCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHH
CLAKPSGETLTVRGTIEGTIGYSPQGENGFGYDPLFIVPSLHKTAAELERDEKAVVSHRG
HHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
QALRKLEAEIIPFMKG
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA