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The map label for this gene is ykoW [H]

Identifier: 229917926

GI number: 229917926

Start: 2139082

End: 2141430

Strand: Reverse

Name: ykoW [H]

Synonym: EAT1b_2205

Alternate gene names: 229917926

Gene position: 2141430-2139082 (Counterclockwise)

Preceding gene: 229917929

Following gene: 229917920

Centisome position: 71.38

GC content: 47.04

Gene sequence:

>2349_bases
ATGGAACAGATTAGCACTCATACAACGAGTCACAATGGATTTTTGATGATGCTCGCTTTCCTCATTGCCAGTGTTTCAGC
CTTGATGGCACTCGAATTAGCGAAGCGGGTCACAGGAGATGTGACAACGTCCCATCGCATCTGGATTTTATTTGGCGGTA
CCACGCTAGGTCTTGGCATCTGGTCCATGCATTTTGTTGCCATGCTCGGTCATGCGTCCTTACATGAGAGCACCTATTCG
ATTTGGCTCATTATCGGATCGATGATTCCGGCGATTGCCGGGTGCATCTTATCGTTCGGTTTGATTTCCCACAAGACGAC
ATGGATGATCTTACTTCAGTCTTCCGGCTTGATGGGATTTGGAATTGTCAGCATGCATTACATTGGGATGGCAGCCATCC
AGAGTGTTCAATTGGACTTTGATCCCTCGTGGGTATTGGTATCCATCGGCATCGCATGGGGCGCTTCCTTCCTAGCCTTA
TGGGTTGGTTTCTTTTCATCCTATTCTACGGAACGGACACCCGTGCCCGTGAAACTGATGTTCTCTCTTCTGATGGGGAC
GGCTATTTTCAGTATGCACCTTGCAGGGATGCGGGCAACGACTATCATCCCTGATGCTTCAGCTGCGAAGCAGGTTCCGA
TTGATCCGACCCTACTCGCATGGCTCGTCACAAGCATCGTGTTTCTCTTGTTTGGGATGTACTTTATTGCGTATACGTTA
GAACGACAAATCCAAAAACGTGACCTCTTCCAAACGACGATTTTAGAATCGACGACGGATGCTGTGGTGACGACGACAAG
CGATGGTGAAATCCAATATCAAAATCAGGCGTTTGCTCACTTATTCGAAGGGCATGCGACAGAACCTTTTTTTCAGGATT
ATCATCCTTTGCTGTCGGCTCAACAGCCGTTCTATCAGCCGGTACAAATTGACACGAATCATCGTACGTTAGAAGTGACG
TCTTACCCACTTCAAGATGGTTCGAACAATCAAGTACTCTGGTTTATCCGAGATGTGACCGAAGCAGTCGCCTCTCAGCG
TCTGATTGAACATATGGCTTTTCACGATGCATTGACGGATTTACCAAATCGGCATAAACTGGATGCCCTCTTGAAGGAAT
GTATCTCACAAGAACGTTCGGTCGCCTGTTTATATATCGACGTAAACCGCTGGCGTTTCCTAAGTGACATTCTCGGGCAT
CACGGAGCAGATGAGTTGATCATTCAAGTCGCTGACCGCCTCAAACATACGATTCACCCAGACGATGTGTTGACACGAAT
CGGACCATCCGAGTTTGTCATCTTACTCTTTGCGCAACGAAGTTCGCTCGCTCATCAAAAGGCTGAAAAATGTATTAAGG
CAATTTCATCCAGCTTCGACGTGGATGGCACGACTCTTGAATTGACAATGAGTGCGGGAATCAGTCATTTCCCTAAGGAC
AGTGCTTCTTCCGAAGAACTTATTCAGTTTTCTCGTCTTGCCGCTGATGAATCCAGACAGGATGGCGAGAATAACATCAA
ATTATTCGAAGAATCATCGCGACCTCAACTCTTGCGCAATATGGAGATAGAAAAAGCGCTCGTCACCGCACTAAGTAATG
ACGAATTGACGCTTGTCTATCAACCGAAAATCGATTTGAAGCGAAATCGATTGGAAGGCGTGGAAGCATTACTTCGCTGG
CAACATCCACAAATCGGAAAGATTGCGCCGTCTGACTTCATCCCGATTGCAGAAAACACGGGGTTAATTCATTCGATTGG
TCATTGGGTCATTCGGGAAGGCTGTCGCACTTGGGTACGTTGGCAACGGACTGGGATACGTCCCTTTACATTATCCCTTA
ACGTCTCCCCGCTCCAATTTGCGCGCGAAGATTTTGTTGATACGCTACAATCCATTCTTTTGGAGACGGGGATGGACCCG
ATGTATCTCGAATTGGAAGTGACCGAGTCCTCGATGCTTTCATATGAAGCCTCAACCCGTGAAAAATTGACACAGTTGCA
TCAGCTCGGGATCCTCATTTCTCTCGATGATTTTGGGACTGGCTATTCTTCGTTCAGCCAACTTCGGGAACTTCCCGTAC
AAGTGCTGAAAATCGATCGAACGTTTATCGAAAACCTGTTCACCGACCGCAATCAAGAGGCCATCGTCCGCTCGATGATT
CAACTCGGTCACAACCTTGGTATGAAAGTTCTCATGGAAGGCGTGGAAACGTCCGCACAATTGGAATGGCTTCTAAAAGA
GTCATGCGATTTTGTTCAAGGGTATTATTTTAGTCGTCCATTAGCCGAGACAGACGTTCCACTTCACGTAAAACAAACAA
CGACCTATCTCGAATTCGGGAAACACTAA

Upstream 100 bases:

>100_bases
ATAGGAAGAAGAGCATTTGAATTTTTTATTATGTAATTTTGAGAGTTCCGCATATAATGAAGTGAACTCTACATTAAAAA
CCCTGTGAGGTATCGACATT

Downstream 100 bases:

>100_bases
AAAATCGCTTCTGTCAGGTGACAGAAGCGATTTTTGATTAAGACACACGTTCTTTTTCTTCTTCCCGAATCAAATGATAT
TGATCGAGAATCAACTGAGT

Product: diguanylate cyclase/phosphodiesterase with MHYT sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 782; Mature: 782

Protein sequence:

>782_residues
MEQISTHTTSHNGFLMMLAFLIASVSALMALELAKRVTGDVTTSHRIWILFGGTTLGLGIWSMHFVAMLGHASLHESTYS
IWLIIGSMIPAIAGCILSFGLISHKTTWMILLQSSGLMGFGIVSMHYIGMAAIQSVQLDFDPSWVLVSIGIAWGASFLAL
WVGFFSSYSTERTPVPVKLMFSLLMGTAIFSMHLAGMRATTIIPDASAAKQVPIDPTLLAWLVTSIVFLLFGMYFIAYTL
ERQIQKRDLFQTTILESTTDAVVTTTSDGEIQYQNQAFAHLFEGHATEPFFQDYHPLLSAQQPFYQPVQIDTNHRTLEVT
SYPLQDGSNNQVLWFIRDVTEAVASQRLIEHMAFHDALTDLPNRHKLDALLKECISQERSVACLYIDVNRWRFLSDILGH
HGADELIIQVADRLKHTIHPDDVLTRIGPSEFVILLFAQRSSLAHQKAEKCIKAISSSFDVDGTTLELTMSAGISHFPKD
SASSEELIQFSRLAADESRQDGENNIKLFEESSRPQLLRNMEIEKALVTALSNDELTLVYQPKIDLKRNRLEGVEALLRW
QHPQIGKIAPSDFIPIAENTGLIHSIGHWVIREGCRTWVRWQRTGIRPFTLSLNVSPLQFAREDFVDTLQSILLETGMDP
MYLELEVTESSMLSYEASTREKLTQLHQLGILISLDDFGTGYSSFSQLRELPVQVLKIDRTFIENLFTDRNQEAIVRSMI
QLGHNLGMKVLMEGVETSAQLEWLLKESCDFVQGYYFSRPLAETDVPLHVKQTTTYLEFGKH

Sequences:

>Translated_782_residues
MEQISTHTTSHNGFLMMLAFLIASVSALMALELAKRVTGDVTTSHRIWILFGGTTLGLGIWSMHFVAMLGHASLHESTYS
IWLIIGSMIPAIAGCILSFGLISHKTTWMILLQSSGLMGFGIVSMHYIGMAAIQSVQLDFDPSWVLVSIGIAWGASFLAL
WVGFFSSYSTERTPVPVKLMFSLLMGTAIFSMHLAGMRATTIIPDASAAKQVPIDPTLLAWLVTSIVFLLFGMYFIAYTL
ERQIQKRDLFQTTILESTTDAVVTTTSDGEIQYQNQAFAHLFEGHATEPFFQDYHPLLSAQQPFYQPVQIDTNHRTLEVT
SYPLQDGSNNQVLWFIRDVTEAVASQRLIEHMAFHDALTDLPNRHKLDALLKECISQERSVACLYIDVNRWRFLSDILGH
HGADELIIQVADRLKHTIHPDDVLTRIGPSEFVILLFAQRSSLAHQKAEKCIKAISSSFDVDGTTLELTMSAGISHFPKD
SASSEELIQFSRLAADESRQDGENNIKLFEESSRPQLLRNMEIEKALVTALSNDELTLVYQPKIDLKRNRLEGVEALLRW
QHPQIGKIAPSDFIPIAENTGLIHSIGHWVIREGCRTWVRWQRTGIRPFTLSLNVSPLQFAREDFVDTLQSILLETGMDP
MYLELEVTESSMLSYEASTREKLTQLHQLGILISLDDFGTGYSSFSQLRELPVQVLKIDRTFIENLFTDRNQEAIVRSMI
QLGHNLGMKVLMEGVETSAQLEWLLKESCDFVQGYYFSRPLAETDVPLHVKQTTTYLEFGKH
>Mature_782_residues
MEQISTHTTSHNGFLMMLAFLIASVSALMALELAKRVTGDVTTSHRIWILFGGTTLGLGIWSMHFVAMLGHASLHESTYS
IWLIIGSMIPAIAGCILSFGLISHKTTWMILLQSSGLMGFGIVSMHYIGMAAIQSVQLDFDPSWVLVSIGIAWGASFLAL
WVGFFSSYSTERTPVPVKLMFSLLMGTAIFSMHLAGMRATTIIPDASAAKQVPIDPTLLAWLVTSIVFLLFGMYFIAYTL
ERQIQKRDLFQTTILESTTDAVVTTTSDGEIQYQNQAFAHLFEGHATEPFFQDYHPLLSAQQPFYQPVQIDTNHRTLEVT
SYPLQDGSNNQVLWFIRDVTEAVASQRLIEHMAFHDALTDLPNRHKLDALLKECISQERSVACLYIDVNRWRFLSDILGH
HGADELIIQVADRLKHTIHPDDVLTRIGPSEFVILLFAQRSSLAHQKAEKCIKAISSSFDVDGTTLELTMSAGISHFPKD
SASSEELIQFSRLAADESRQDGENNIKLFEESSRPQLLRNMEIEKALVTALSNDELTLVYQPKIDLKRNRLEGVEALLRW
QHPQIGKIAPSDFIPIAENTGLIHSIGHWVIREGCRTWVRWQRTGIRPFTLSLNVSPLQFAREDFVDTLQSILLETGMDP
MYLELEVTESSMLSYEASTREKLTQLHQLGILISLDDFGTGYSSFSQLRELPVQVLKIDRTFIENLFTDRNQEAIVRSMI
QLGHNLGMKVLMEGVETSAQLEWLLKESCDFVQGYYFSRPLAETDVPLHVKQTTTYLEFGKH

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081921, Length=427, Percent_Identity=33.7236533957845, Blast_Score=259, Evalue=7e-70,
Organism=Escherichia coli, GI1787541, Length=426, Percent_Identity=29.5774647887324, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI226510982, Length=413, Percent_Identity=30.0242130750605, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1790496, Length=238, Percent_Identity=34.8739495798319, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI87081845, Length=260, Percent_Identity=33.0769230769231, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1786507, Length=237, Percent_Identity=32.4894514767932, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1788502, Length=255, Percent_Identity=31.3725490196078, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI1787055, Length=254, Percent_Identity=31.1023622047244, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=32, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI87081743, Length=239, Percent_Identity=30.9623430962343, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI87082096, Length=424, Percent_Identity=25.2358490566038, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788849, Length=430, Percent_Identity=25.5813953488372, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788381, Length=452, Percent_Identity=23.0088495575221, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI87081881, Length=200, Percent_Identity=27, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 88057; Mature: 88057

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50924 MHYT ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQISTHTTSHNGFLMMLAFLIASVSALMALELAKRVTGDVTTSHRIWILFGGTTLGLGI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHH
WSMHFVAMLGHASLHESTYSIWLIIGSMIPAIAGCILSFGLISHKTTWMILLQSSGLMGF
HHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHH
GIVSMHYIGMAAIQSVQLDFDPSWVLVSIGIAWGASFLALWVGFFSSYSTERTPVPVKLM
HHHHHHHHHHHHHHHEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
FSLLMGTAIFSMHLAGMRATTIIPDASAAKQVPIDPTLLAWLVTSIVFLLFGMYFIAYTL
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERQIQKRDLFQTTILESTTDAVVTTTSDGEIQYQNQAFAHLFEGHATEPFFQDYHPLLSA
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECHHHHHHHHCCCCCCCHHHHHHHHHCC
QQPFYQPVQIDTNHRTLEVTSYPLQDGSNNQVLWFIRDVTEAVASQRLIEHMAFHDALTD
CCCCCCCEEECCCCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
LPNRHKLDALLKECISQERSVACLYIDVNRWRFLSDILGHHGADELIIQVADRLKHTIHP
CCCCHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
DDVLTRIGPSEFVILLFAQRSSLAHQKAEKCIKAISSSFDVDGTTLELTMSAGISHFPKD
HHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCC
SASSEELIQFSRLAADESRQDGENNIKLFEESSRPQLLRNMEIEKALVTALSNDELTLVY
CCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHCCHHHHHHHHHCCCCCEEEEE
QPKIDLKRNRLEGVEALLRWQHPQIGKIAPSDFIPIAENTGLIHSIGHWVIREGCRTWVR
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
WQRTGIRPFTLSLNVSPLQFAREDFVDTLQSILLETGMDPMYLELEVTESSMLSYEASTR
HHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHCHHHH
EKLTQLHQLGILISLDDFGTGYSSFSQLRELPVQVLKIDRTFIENLFTDRNQEAIVRSMI
HHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QLGHNLGMKVLMEGVETSAQLEWLLKESCDFVQGYYFSRPLAETDVPLHVKQTTTYLEFG
HHHHCCCHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEECHHHHHHCC
KH
CC
>Mature Secondary Structure
MEQISTHTTSHNGFLMMLAFLIASVSALMALELAKRVTGDVTTSHRIWILFGGTTLGLGI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHH
WSMHFVAMLGHASLHESTYSIWLIIGSMIPAIAGCILSFGLISHKTTWMILLQSSGLMGF
HHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHH
GIVSMHYIGMAAIQSVQLDFDPSWVLVSIGIAWGASFLALWVGFFSSYSTERTPVPVKLM
HHHHHHHHHHHHHHHEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
FSLLMGTAIFSMHLAGMRATTIIPDASAAKQVPIDPTLLAWLVTSIVFLLFGMYFIAYTL
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERQIQKRDLFQTTILESTTDAVVTTTSDGEIQYQNQAFAHLFEGHATEPFFQDYHPLLSA
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECHHHHHHHHCCCCCCCHHHHHHHHHCC
QQPFYQPVQIDTNHRTLEVTSYPLQDGSNNQVLWFIRDVTEAVASQRLIEHMAFHDALTD
CCCCCCCEEECCCCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
LPNRHKLDALLKECISQERSVACLYIDVNRWRFLSDILGHHGADELIIQVADRLKHTIHP
CCCCHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
DDVLTRIGPSEFVILLFAQRSSLAHQKAEKCIKAISSSFDVDGTTLELTMSAGISHFPKD
HHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCC
SASSEELIQFSRLAADESRQDGENNIKLFEESSRPQLLRNMEIEKALVTALSNDELTLVY
CCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHCCHHHHHHHHHCCCCCEEEEE
QPKIDLKRNRLEGVEALLRWQHPQIGKIAPSDFIPIAENTGLIHSIGHWVIREGCRTWVR
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
WQRTGIRPFTLSLNVSPLQFAREDFVDTLQSILLETGMDPMYLELEVTESSMLSYEASTR
HHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHCHHHH
EKLTQLHQLGILISLDDFGTGYSSFSQLRELPVQVLKIDRTFIENLFTDRNQEAIVRSMI
HHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QLGHNLGMKVLMEGVETSAQLEWLLKESCDFVQGYYFSRPLAETDVPLHVKQTTTYLEFG
HHHHCCCHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEECHHHHHHCC
KH
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]