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The map label for this gene is bglC [H]

Identifier: 229917910

GI number: 229917910

Start: 2124623

End: 2126029

Strand: Reverse

Name: bglC [H]

Synonym: EAT1b_2188

Alternate gene names: 229917910

Gene position: 2126029-2124623 (Counterclockwise)

Preceding gene: 229917911

Following gene: 229917909

Centisome position: 70.87

GC content: 50.39

Gene sequence:

>1407_bases
TTGAAAATGCCTAAAGATTTCTTGTTCGGCGCTGCTTCGGCCTCTTACCAGGTCGAAGGCGCATGGAACGAGGACGGGAA
AGGCCTCTCGAACTGGGACGTCTTCTCGAAAATTCCTGGTAAGACATTTGAAAACACAAACGGCGACGTCGCAGTCGACC
ATTACCATCGTTATAAAGAAGATATCGCGCTCATGGCGGAGATGGGACTCGAATCGTATCGTTTCTCCATCTCATGGCCG
CGTATCTTCCCGAACGGTACGGGTGAAGTGAACGAAAAAGGACTCGAGTTCTATAACAACTTGATCGACGAATGTTTGAA
ACATGACATCGTCCCATTCGTCACGCTCTACCATTGGGACCTCCCACAAGCACTTGAAGAAAAAGGCGGCTGGAAGAACA
AAGAGACAGTTGACGCATTCGTCCGTTTCGCAGATACTTGCTTCCAATCGTTCGGTGACCGTGTCAACCACTGGATCACG
TTCAACGAAGCGGTCATCTTCTGCTCACTTGGATACTTAACAGGCGCACACCCGCCAGGTATCGAAGGCGACGTCAAAGG
ATATTTCCAAACGACACATAACGTCTTCGTCGCTCACGCCCGTGCCGTTGAGCTCTTCAAACAAAACGGTCATACTGGCG
AAATCGGGATCACACACGTGTTCAACCCGGCGTTCAGTATCGATGACGCAGAGGAGAACAAGTTTGCCGAAATGCATGCG
AACGCTTATGCGACACATTGGTTCTATGACCCGATCTTGAAAGGTGAATATCCAGAGTACGTCGTGAACGGTCTAAGCGA
ACAAGGCCTCCTTCCTGAAATGACGGAGGAAGAACTCGACGTCTTGAAACGTACCGCTCCGATGAACGACTTTATCGGTC
TCAACTACTACAGCCCGCAGCGCGTCATGAAGAATGACTCGGCGCTCGTCATGGCCGGTGGACGTGAGAACTCGACAGGT
CGTCCGGGTAACCCATCGTTCGATGGCGTCTACAAGACGGTCAAGATGGATGACAAAGTATATACGAAGTGGGATTGGGA
GATCTCACCGGAAGCGTTCCTCGCTGGGATGCACATGCTGAAAGATCGTTACGGCGACGTCAAAATCTATATCACAGAGA
ACGGTCTCGGTGATGTCGACCCAATCGTCGACGGTGAGATCATGGACACGCCACGGATCGAGTACATCGAAGGACACCTT
CGTGCAGTCAAACATGCTGTTCAACAAGGCATCAACGTTGCCGGTTACTATGCTTGGTCTGTAATCGACCTACTCAGCTG
GTTGAACGGTTATAAGAAACAATACGGCTTCATCTATGTCGACCACAACAACGGTCTCGCACGGAAGAAGAAACAGTCGT
TCCATTGGTATAAAGAGATCATCGCCACGCGCGCTGAAGACCTATAA

Upstream 100 bases:

>100_bases
AATCGACGTCATCAACACAGTCGACTACGGCATGATGAACGGTGCGAAAGTATTAGACCACTCATTGAAACTTGTAAATA
AATAAACTGAGGTGATGACT

Downstream 100 bases:

>100_bases
GGAGGTTCCCCTATGAGCCGCTTAGAAAGAGTATTTGAAAAGTTCACCCCTGCTTTTGTTCGTTTTGCGAACGCCAAGCC
CGTCCTTGCGATTAAGGACG

Product: beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKMPKDFLFGAASASYQVEGAWNEDGKGLSNWDVFSKIPGKTFENTNGDVAVDHYHRYKEDIALMAEMGLESYRFSISWP
RIFPNGTGEVNEKGLEFYNNLIDECLKHDIVPFVTLYHWDLPQALEEKGGWKNKETVDAFVRFADTCFQSFGDRVNHWIT
FNEAVIFCSLGYLTGAHPPGIEGDVKGYFQTTHNVFVAHARAVELFKQNGHTGEIGITHVFNPAFSIDDAEENKFAEMHA
NAYATHWFYDPILKGEYPEYVVNGLSEQGLLPEMTEEELDVLKRTAPMNDFIGLNYYSPQRVMKNDSALVMAGGRENSTG
RPGNPSFDGVYKTVKMDDKVYTKWDWEISPEAFLAGMHMLKDRYGDVKIYITENGLGDVDPIVDGEIMDTPRIEYIEGHL
RAVKHAVQQGINVAGYYAWSVIDLLSWLNGYKKQYGFIYVDHNNGLARKKKQSFHWYKEIIATRAEDL

Sequences:

>Translated_468_residues
MKMPKDFLFGAASASYQVEGAWNEDGKGLSNWDVFSKIPGKTFENTNGDVAVDHYHRYKEDIALMAEMGLESYRFSISWP
RIFPNGTGEVNEKGLEFYNNLIDECLKHDIVPFVTLYHWDLPQALEEKGGWKNKETVDAFVRFADTCFQSFGDRVNHWIT
FNEAVIFCSLGYLTGAHPPGIEGDVKGYFQTTHNVFVAHARAVELFKQNGHTGEIGITHVFNPAFSIDDAEENKFAEMHA
NAYATHWFYDPILKGEYPEYVVNGLSEQGLLPEMTEEELDVLKRTAPMNDFIGLNYYSPQRVMKNDSALVMAGGRENSTG
RPGNPSFDGVYKTVKMDDKVYTKWDWEISPEAFLAGMHMLKDRYGDVKIYITENGLGDVDPIVDGEIMDTPRIEYIEGHL
RAVKHAVQQGINVAGYYAWSVIDLLSWLNGYKKQYGFIYVDHNNGLARKKKQSFHWYKEIIATRAEDL
>Mature_468_residues
MKMPKDFLFGAASASYQVEGAWNEDGKGLSNWDVFSKIPGKTFENTNGDVAVDHYHRYKEDIALMAEMGLESYRFSISWP
RIFPNGTGEVNEKGLEFYNNLIDECLKHDIVPFVTLYHWDLPQALEEKGGWKNKETVDAFVRFADTCFQSFGDRVNHWIT
FNEAVIFCSLGYLTGAHPPGIEGDVKGYFQTTHNVFVAHARAVELFKQNGHTGEIGITHVFNPAFSIDDAEENKFAEMHA
NAYATHWFYDPILKGEYPEYVVNGLSEQGLLPEMTEEELDVLKRTAPMNDFIGLNYYSPQRVMKNDSALVMAGGRENSTG
RPGNPSFDGVYKTVKMDDKVYTKWDWEISPEAFLAGMHMLKDRYGDVKIYITENGLGDVDPIVDGEIMDTPRIEYIEGHL
RAVKHAVQQGINVAGYYAWSVIDLLSWLNGYKKQYGFIYVDHNNGLARKKKQSFHWYKEIIATRAEDL

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=481, Percent_Identity=35.966735966736, Blast_Score=291, Evalue=1e-78,
Organism=Homo sapiens, GI32481206, Length=486, Percent_Identity=34.9794238683128, Blast_Score=281, Evalue=6e-76,
Organism=Homo sapiens, GI13273313, Length=461, Percent_Identity=36.0086767895879, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI28376633, Length=471, Percent_Identity=33.9702760084926, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI24497614, Length=467, Percent_Identity=30.406852248394, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI190360571, Length=99, Percent_Identity=44.4444444444444, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI2367174, Length=501, Percent_Identity=35.9281437125749, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI2367270, Length=482, Percent_Identity=37.1369294605809, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI1789070, Length=493, Percent_Identity=34.4827586206897, Blast_Score=251, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI17552856, Length=475, Percent_Identity=34.1052631578947, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI17539390, Length=486, Percent_Identity=32.3045267489712, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI21356577, Length=492, Percent_Identity=34.5528455284553, Blast_Score=268, Evalue=6e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53331; Mature: 53331

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMPKDFLFGAASASYQVEGAWNEDGKGLSNWDVFSKIPGKTFENTNGDVAVDHYHRYKE
CCCCHHHHEECCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEHHHHHHHH
DIALMAEMGLESYRFSISWPRIFPNGTGEVNEKGLEFYNNLIDECLKHDIVPFVTLYHWD
HHHHHHHHCCCCEEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
LPQALEEKGGWKNKETVDAFVRFADTCFQSFGDRVNHWITFNEAVIFCSLGYLTGAHPPG
CHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCEEEEEEEHHHCCCCCCC
IEGDVKGYFQTTHNVFVAHARAVELFKQNGHTGEIGITHVFNPAFSIDDAEENKFAEMHA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHC
NAYATHWFYDPILKGEYPEYVVNGLSEQGLLPEMTEEELDVLKRTAPMNDFIGLNYYSPQ
CCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCH
RVMKNDSALVMAGGRENSTGRPGNPSFDGVYKTVKMDDKVYTKWDWEISPEAFLAGMHML
HHHCCCCEEEEECCCCCCCCCCCCCCCCHHEEEEEECCCEEEEECCCCCHHHHHHHHHHH
KDRYGDVKIYITENGLGDVDPIVDGEIMDTPRIEYIEGHLRAVKHAVQQGINVAGYYAWS
HHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHH
VIDLLSWLNGYKKQYGFIYVDHNNGLARKKKQSFHWYKEIIATRAEDL
HHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKMPKDFLFGAASASYQVEGAWNEDGKGLSNWDVFSKIPGKTFENTNGDVAVDHYHRYKE
CCCCHHHHEECCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEHHHHHHHH
DIALMAEMGLESYRFSISWPRIFPNGTGEVNEKGLEFYNNLIDECLKHDIVPFVTLYHWD
HHHHHHHHCCCCEEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
LPQALEEKGGWKNKETVDAFVRFADTCFQSFGDRVNHWITFNEAVIFCSLGYLTGAHPPG
CHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCEEEEEEEHHHCCCCCCC
IEGDVKGYFQTTHNVFVAHARAVELFKQNGHTGEIGITHVFNPAFSIDDAEENKFAEMHA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHC
NAYATHWFYDPILKGEYPEYVVNGLSEQGLLPEMTEEELDVLKRTAPMNDFIGLNYYSPQ
CCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCH
RVMKNDSALVMAGGRENSTGRPGNPSFDGVYKTVKMDDKVYTKWDWEISPEAFLAGMHML
HHHCCCCEEEEECCCCCCCCCCCCCCCCHHEEEEEECCCEEEEECCCCCHHHHHHHHHHH
KDRYGDVKIYITENGLGDVDPIVDGEIMDTPRIEYIEGHLRAVKHAVQQGINVAGYYAWS
HHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHH
VIDLLSWLNGYKKQYGFIYVDHNNGLARKKKQSFHWYKEIIATRAEDL
HHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]