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The map label for this gene is ywbA [H]

Identifier: 229917909

GI number: 229917909

Start: 2123282

End: 2124610

Strand: Reverse

Name: ywbA [H]

Synonym: EAT1b_2187

Alternate gene names: 229917909

Gene position: 2124610-2123282 (Counterclockwise)

Preceding gene: 229917910

Following gene: 229917908

Centisome position: 70.82

GC content: 51.92

Gene sequence:

>1329_bases
ATGAGCCGCTTAGAAAGAGTATTTGAAAAGTTCACCCCTGCTTTTGTTCGTTTTGCGAACGCCAAGCCCGTCCTTGCGAT
TAAGGACGGGTTCATCCTCACGATGCCGATGACCATCATCGGGTCGCTGTTCCTTCTCATCCTGGCGTTACCGATTCCAG
GTTGGGCTGACTTCATGTCAGGTTTATTCGGGGCAGACTGGTCACTCCCGCTCACGCAAGTCGTCGGTGCGACGTTTGAC
ATCCTTGCTTTGATCGGTGTTTTTGGAATCGCTTACTCGTACGTCAAGAATGAAAAAATCGAAGGCGTACCAGCTGGTAT
CCTCGGAATCATCTCGTTCCTCATCATCACACAGGCTTCTGTACTGTCTGAAGGCGGAGAAACTGTTACCGGGGTTATCC
CGAAAGTATGGACAGGTGGACAAGGTGTCCTCGCTGCCATCCTCGTCGGATTGACAGTCGGATTCATCTACTCGCAGTTC
ATCAAACGCGGAATCAGCATTAAAATGCCAGACGGTGTCCCGCCAGGCGTATCGAACTCATTCTCTGCACTTGTTCCTGG
TTTGGCGATCATCTCGCTCGCCGTTGCGACGTTTGCGATTTTCCAAGCGGTGGCAGAGCGTACGTTCACAGAAGTCATCT
ATGATGTGCTTCAAGCACCGCTTCAAAACTTGACGGACACACTAGCTGGAGCCGTCATCATCATGGTGCTCATGTCCGTC
ATGTGGTGGTGTGGAATTCACGGTGCCGCAATCCTCATGGGAATCATGGGACCCCTTCTCACAGCGAACGCACTTCAAAA
CCAAGCCATCCTCGATGCAGGTGGTACGCTTGTCGCTGGCGAGAACGCAAAAATCGTTACAATCCAGTTCCTCGATGTGT
TCACGAAACTCGGTGGATCAGGAATTACAATCGGCTTCATCATTGCCGTCTTAATCGTTGCACGCTCGGCACACTTGAAG
CAGCTCGGGAAGTTGTCACTTGCACCAAGTATCTTCAACATCAATGAGCCGGTCATCTTCGGGATGCCGATCGTCTTCAA
CCCGATCATGTTCGTCCCATTCGTCGTCGTGCCAGCCATCGCTTCATTCATGGTCTACTTTGCCATCCTTTGGGGTTGGG
TCGAGCCGTTCAACGCGCTTCAAGTACCATGGACGACACCTCCAGTCATCTCTGGATTCTTGATTGGCGGATGGCGCGCC
GCTCTCTTACAGATTGCAACAATCGCCATGGCCGTAGCCGTCTACCTCCCGTTCGTTCGCATTCAAGACCGCGTTTCGTA
CGGTGAAGAATTGAAAGCACAAGAAGGCTCAGATCAAGCATCAGCCTGA

Upstream 100 bases:

>100_bases
CGACCACAACAACGGTCTCGCACGGAAGAAGAAACAGTCGTTCCATTGGTATAAAGAGATCATCGCCACGCGCGCTGAAG
ACCTATAAGGAGGTTCCCCT

Downstream 100 bases:

>100_bases
AACAAAAACGACGGCCCTTCTCAGTAATGAGGAGGGCTGTTATCATGTAGGAAAAGATTGGAAAGTTGGGTTAGGATGAA
AAGAAAAGTTACCGTCATGT

Product: PTS system, lactose/cellobiose family IIC subunit

Products: protein histidine; sugar phosphate

Alternate protein names: Putative PTS system EIIC component [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSRLERVFEKFTPAFVRFANAKPVLAIKDGFILTMPMTIIGSLFLLILALPIPGWADFMSGLFGADWSLPLTQVVGATFD
ILALIGVFGIAYSYVKNEKIEGVPAGILGIISFLIITQASVLSEGGETVTGVIPKVWTGGQGVLAAILVGLTVGFIYSQF
IKRGISIKMPDGVPPGVSNSFSALVPGLAIISLAVATFAIFQAVAERTFTEVIYDVLQAPLQNLTDTLAGAVIIMVLMSV
MWWCGIHGAAILMGIMGPLLTANALQNQAILDAGGTLVAGENAKIVTIQFLDVFTKLGGSGITIGFIIAVLIVARSAHLK
QLGKLSLAPSIFNINEPVIFGMPIVFNPIMFVPFVVVPAIASFMVYFAILWGWVEPFNALQVPWTTPPVISGFLIGGWRA
ALLQIATIAMAVAVYLPFVRIQDRVSYGEELKAQEGSDQASA

Sequences:

>Translated_442_residues
MSRLERVFEKFTPAFVRFANAKPVLAIKDGFILTMPMTIIGSLFLLILALPIPGWADFMSGLFGADWSLPLTQVVGATFD
ILALIGVFGIAYSYVKNEKIEGVPAGILGIISFLIITQASVLSEGGETVTGVIPKVWTGGQGVLAAILVGLTVGFIYSQF
IKRGISIKMPDGVPPGVSNSFSALVPGLAIISLAVATFAIFQAVAERTFTEVIYDVLQAPLQNLTDTLAGAVIIMVLMSV
MWWCGIHGAAILMGIMGPLLTANALQNQAILDAGGTLVAGENAKIVTIQFLDVFTKLGGSGITIGFIIAVLIVARSAHLK
QLGKLSLAPSIFNINEPVIFGMPIVFNPIMFVPFVVVPAIASFMVYFAILWGWVEPFNALQVPWTTPPVISGFLIGGWRA
ALLQIATIAMAVAVYLPFVRIQDRVSYGEELKAQEGSDQASA
>Mature_441_residues
SRLERVFEKFTPAFVRFANAKPVLAIKDGFILTMPMTIIGSLFLLILALPIPGWADFMSGLFGADWSLPLTQVVGATFDI
LALIGVFGIAYSYVKNEKIEGVPAGILGIISFLIITQASVLSEGGETVTGVIPKVWTGGQGVLAAILVGLTVGFIYSQFI
KRGISIKMPDGVPPGVSNSFSALVPGLAIISLAVATFAIFQAVAERTFTEVIYDVLQAPLQNLTDTLAGAVIIMVLMSVM
WWCGIHGAAILMGIMGPLLTANALQNQAILDAGGTLVAGENAKIVTIQFLDVFTKLGGSGITIGFIIAVLIVARSAHLKQ
LGKLSLAPSIFNINEPVIFGMPIVFNPIMFVPFVVVPAIASFMVYFAILWGWVEPFNALQVPWTTPPVISGFLIGGWRAA
LLQIATIAMAVAVYLPFVRIQDRVSYGEELKAQEGSDQASA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=463, Percent_Identity=32.3974082073434, Blast_Score=205, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 47035; Mature: 46903

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLERVFEKFTPAFVRFANAKPVLAIKDGFILTMPMTIIGSLFLLILALPIPGWADFMS
CCHHHHHHHHHCHHHHHHCCCCCEEEEECCEEEEEHHHHHHHHHHHHHHHCCCCHHHHHH
GLFGADWSLPLTQVVGATFDILALIGVFGIAYSYVKNEKIEGVPAGILGIISFLIITQAS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VLSEGGETVTGVIPKVWTGGQGVLAAILVGLTVGFIYSQFIKRGISIKMPDGVPPGVSNS
HHHCCCCEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCC
FSALVPGLAIISLAVATFAIFQAVAERTFTEVIYDVLQAPLQNLTDTLAGAVIIMVLMSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MWWCGIHGAAILMGIMGPLLTANALQNQAILDAGGTLVAGENAKIVTIQFLDVFTKLGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCEEECCCCCEEEHHHHHHHHHHCCC
GITIGFIIAVLIVARSAHLKQLGKLSLAPSIFNINEPVIFGMPIVFNPIMFVPFVVVPAI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
ASFMVYFAILWGWVEPFNALQVPWTTPPVISGFLIGGWRAALLQIATIAMAVAVYLPFVR
HHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQDRVSYGEELKAQEGSDQASA
HHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SRLERVFEKFTPAFVRFANAKPVLAIKDGFILTMPMTIIGSLFLLILALPIPGWADFMS
CHHHHHHHHHCHHHHHHCCCCCEEEEECCEEEEEHHHHHHHHHHHHHHHCCCCHHHHHH
GLFGADWSLPLTQVVGATFDILALIGVFGIAYSYVKNEKIEGVPAGILGIISFLIITQAS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VLSEGGETVTGVIPKVWTGGQGVLAAILVGLTVGFIYSQFIKRGISIKMPDGVPPGVSNS
HHHCCCCEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCC
FSALVPGLAIISLAVATFAIFQAVAERTFTEVIYDVLQAPLQNLTDTLAGAVIIMVLMSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MWWCGIHGAAILMGIMGPLLTANALQNQAILDAGGTLVAGENAKIVTIQFLDVFTKLGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCEEECCCCCEEEHHHHHHHHHHCCC
GITIGFIIAVLIVARSAHLKQLGKLSLAPSIFNINEPVIFGMPIVFNPIMFVPFVVVPAI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
ASFMVYFAILWGWVEPFNALQVPWTTPPVISGFLIGGWRAALLQIATIAMAVAVYLPFVR
HHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQDRVSYGEELKAQEGSDQASA
HHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]