| Definition | Yersinia pseudotuberculosis IP 32953, complete genome. |
|---|---|
| Accession | NC_006155 |
| Length | 4,744,671 |
Click here to switch to the map view.
The map label for this gene is mrcA
Identifier: 229310100
GI number: 229310100
Start: 4455459
End: 4458014
Strand: Direct
Name: mrcA
Synonym: YPTB3756
Alternate gene names: 229310100
Gene position: 4455459-4458014 (Clockwise)
Preceding gene: 51598033
Following gene: 51598048
Centisome position: 93.9
GC content: 51.72
Gene sequence:
>2556_bases GTGAAGTTCGTAAAGTATTTTTTAATCCTTGCGGTGTGTTGCATTTTACTGGGAGCAGCCTCGATATTTGGCCTGTACAA ATATATTGAGCCGCAGCTACCCGATGTTGCCACGCTGAAAGACATCCGGCTGCAAACACCTATGCAGGTGTATAGCGCCG AAGGCGAATTGATCGCTCAATTCGGCGAAAAACGTCGTATCCCATTGACGTTGAATCAAATACCACCAGAAATGGTGCAT GCGTTTATCGCCACAGAAGACAGCCGTTTTTACGATCATCACGGTGTCGACCCTGTGGGGATCCTACGTGCAGTCTCTAT CGCCATGTTGTCTGGTCGCGCCTCCCAAGGGGCGAGTACCATTACCCAGCAATTGGCGAGGAACTTCTTTTTAAGCCCTG AACGGACTTTGATGCGAAAAATCAAGGAAGCATTTCTGGCTATCCGCATCGAACAGATGCTGACCAAAGATGAAATCCTT GAGCTGTATCTGAACAAAATTTATCTCGGTTACCGCGCCTATGGTGTCGGTGCTGCGGCCCAAGTCTATTTCGGCAAAGA AGTCCATGAATTGACCCTCAGCCAAATAGCGATGATCGCCGGGTTACCTAAAGCGCCTTCTACGTTTAACCCGCTCTACT CATATGACAGAGCCGTGGCACGGCGTAATGTGGTGCTGCTACGTATGCTGGATGAAAAATACATCACTCAGGCGCAATAC GATCAAGCCCGCAGTGAAGAGTTGGTGGCTAACTACCATGTACCGCAAATCGCCTTTTCAGCGCCCTATCTGGCTGAAAT GGTGCGTCAGGAGATGATTAAACGTTACGGTGAAAATGCGTATACCGACGGTTATCAGGTCTATACCACGATCACCAGAA AGCTACAGTTGGCGGCAGTTGATTCATTACGCGCCAACGTGCTGGCTTATGATATGCGCCATGGCTATCGCGGCCCGTCC AATGTGTTATGGAAGGTGGGCGAAAGTGCCTGGAGCCGTGAACAGATTATCGATTCACTGAAAGCATTGCCGGTGTATGG CCCGCTGTTACCTGCAGTAGTCACCGAGGCGGATGCCGCACAAGCTACGGCAATGCTGGCTGATGGCAGCAACGTGACCT TGCCGATGGTCGGTATACGGTGGGCGCGTCCGTTTAAATCGGATAACGCCCAAGGTCCGGTCCCCAAAAAAGCGACTGAT GTCGTTCAGCCTGGTCAGCAAATTTGGGTCAGAAAGGTCGATGATAACTGGTGGCTGGCTCAAGTGCCGGACGTCAATTC TGCGCTGGTGTCTATCGATCCCAATAACGGTGCAATTAAAGCGCTAGTAGGCGGTTTTGATTTTAACCAAAGCAAATTTA ACCGGGCAACGCAGGCACTGCGTCAGGTTGGCTCGAATATTAAGCCATTCCTGTATACCGCCGCGATGGACAAAGGCCTG ACGCTGGCCACTATCCTCAATGACCTGCCAATCACCCGTTGGGATTCTGGCGCAGGCACCGACTGGCGGCCAAAAAACTC ACCTCCCACTTACGATGGCCCTATCCGTTTGCGTCAGGGTTTAGGCCAATCGAAAAACGTGGTCATGGTGCGGGCAATGC GGGCCATGGGGGTGGATTACGCGGCTGAGTATTTGCAGCGCTTTGGTTTCCCTGCGCAGAATATCGTGCATTCAGAATCA CTGGCTCTGGGTTCTGCCTCCTTTACACCATTACAGCTAGTCCGTGGCTATGCCGTGCTAGCAAATGGCGGTTACCTGGT TGATCCGTACTTCATCACTAAAATCACTGATGATGTCGGTAATGTTCTGTTTGAAACAAAGCCGAAGGTTGTCTGTGATA ACTGTAACTTGCCGGTCATTTACGGTGATACCCAACGTTCAGTTGTACTTTCTGACGACAATATTGAGAACGTTGCAACC TCGCAGAACCAGAATGCCAGTAACGTGCCAATGCCAGAGCTGGAACAGGTGACACCGGCACAAACGACGCTAAATAGCGA ACAGCAATATGCGCCACACGTGATAAGCACCCCGCTGGCGTTCTTGATGCGTGATGCATTGAATTCTAATATTTTCGGGG AACCTGGCTGGATGGGTACGGGCTGGCGTGCGGGTCGTGACCTGAAACGTAAGGATATCGGCGGTAAAACGGGTACGACA AACAGCTCGAAGGATGCCTGGTTCTCCGGCTACGGCCCAGATACCGTGACATCCGTCTGGATTGGCTTTGATGACCATCG CCGTAATTTGGGCCGCAGCACGGCATCAGGGGCGATACCAGACCAAATTTCCGGAGCAGAAGGCGGGGCGAAGACGGCCC AGCCAGCATGGAATGACTTTATGAAGGTGGCGCTTGAGGGCTTGCCAGAGAAGCAGGTTCCACCACCACCGGGTATCGTC AGTGTCGTGATTGATAAGCAAACAGGCAAGTTATCTAATGGCGGGCCGGGCAGCCGCTCAGAGTACTTTATCGACGGGAC ACAACCCACTGAGCATACGGTACATGAAGTTGGTACCACATTGATGGATAACGGCCAGACTCACGAACTGTTCTGA
Upstream 100 bases:
>100_bases GAGACAGAATAAAAGAACGTATCCATGGTGCGGGCTTGCCTTTATACTACGTCGCGGTTGTTTATAAACTGCCCAATTGA CATTGAATGGGAAATCTCAG
Downstream 100 bases:
>100_bases TAGCAGCCTGGTGTAAAAAACTTATCTAAAAAGCCAGATGATCTGATGATCATCTGGCTTTTTTATAAATTACTCGTATA AAAAATAAGTTACGTCAGAA
Product: peptidoglycan synthetase
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 851; Mature: 851
Protein sequence:
>851_residues MKFVKYFLILAVCCILLGAASIFGLYKYIEPQLPDVATLKDIRLQTPMQVYSAEGELIAQFGEKRRIPLTLNQIPPEMVH AFIATEDSRFYDHHGVDPVGILRAVSIAMLSGRASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQMLTKDEIL ELYLNKIYLGYRAYGVGAAAQVYFGKEVHELTLSQIAMIAGLPKAPSTFNPLYSYDRAVARRNVVLLRMLDEKYITQAQY DQARSEELVANYHVPQIAFSAPYLAEMVRQEMIKRYGENAYTDGYQVYTTITRKLQLAAVDSLRANVLAYDMRHGYRGPS NVLWKVGESAWSREQIIDSLKALPVYGPLLPAVVTEADAAQATAMLADGSNVTLPMVGIRWARPFKSDNAQGPVPKKATD VVQPGQQIWVRKVDDNWWLAQVPDVNSALVSIDPNNGAIKALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL TLATILNDLPITRWDSGAGTDWRPKNSPPTYDGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHSES LALGSASFTPLQLVRGYAVLANGGYLVDPYFITKITDDVGNVLFETKPKVVCDNCNLPVIYGDTQRSVVLSDDNIENVAT SQNQNASNVPMPELEQVTPAQTTLNSEQQYAPHVISTPLAFLMRDALNSNIFGEPGWMGTGWRAGRDLKRKDIGGKTGTT NSSKDAWFSGYGPDTVTSVWIGFDDHRRNLGRSTASGAIPDQISGAEGGAKTAQPAWNDFMKVALEGLPEKQVPPPPGIV SVVIDKQTGKLSNGGPGSRSEYFIDGTQPTEHTVHEVGTTLMDNGQTHELF
Sequences:
>Translated_851_residues MKFVKYFLILAVCCILLGAASIFGLYKYIEPQLPDVATLKDIRLQTPMQVYSAEGELIAQFGEKRRIPLTLNQIPPEMVH AFIATEDSRFYDHHGVDPVGILRAVSIAMLSGRASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQMLTKDEIL ELYLNKIYLGYRAYGVGAAAQVYFGKEVHELTLSQIAMIAGLPKAPSTFNPLYSYDRAVARRNVVLLRMLDEKYITQAQY DQARSEELVANYHVPQIAFSAPYLAEMVRQEMIKRYGENAYTDGYQVYTTITRKLQLAAVDSLRANVLAYDMRHGYRGPS NVLWKVGESAWSREQIIDSLKALPVYGPLLPAVVTEADAAQATAMLADGSNVTLPMVGIRWARPFKSDNAQGPVPKKATD VVQPGQQIWVRKVDDNWWLAQVPDVNSALVSIDPNNGAIKALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL TLATILNDLPITRWDSGAGTDWRPKNSPPTYDGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHSES LALGSASFTPLQLVRGYAVLANGGYLVDPYFITKITDDVGNVLFETKPKVVCDNCNLPVIYGDTQRSVVLSDDNIENVAT SQNQNASNVPMPELEQVTPAQTTLNSEQQYAPHVISTPLAFLMRDALNSNIFGEPGWMGTGWRAGRDLKRKDIGGKTGTT NSSKDAWFSGYGPDTVTSVWIGFDDHRRNLGRSTASGAIPDQISGAEGGAKTAQPAWNDFMKVALEGLPEKQVPPPPGIV SVVIDKQTGKLSNGGPGSRSEYFIDGTQPTEHTVHEVGTTLMDNGQTHELF >Mature_851_residues MKFVKYFLILAVCCILLGAASIFGLYKYIEPQLPDVATLKDIRLQTPMQVYSAEGELIAQFGEKRRIPLTLNQIPPEMVH AFIATEDSRFYDHHGVDPVGILRAVSIAMLSGRASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQMLTKDEIL ELYLNKIYLGYRAYGVGAAAQVYFGKEVHELTLSQIAMIAGLPKAPSTFNPLYSYDRAVARRNVVLLRMLDEKYITQAQY DQARSEELVANYHVPQIAFSAPYLAEMVRQEMIKRYGENAYTDGYQVYTTITRKLQLAAVDSLRANVLAYDMRHGYRGPS NVLWKVGESAWSREQIIDSLKALPVYGPLLPAVVTEADAAQATAMLADGSNVTLPMVGIRWARPFKSDNAQGPVPKKATD VVQPGQQIWVRKVDDNWWLAQVPDVNSALVSIDPNNGAIKALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL TLATILNDLPITRWDSGAGTDWRPKNSPPTYDGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHSES LALGSASFTPLQLVRGYAVLANGGYLVDPYFITKITDDVGNVLFETKPKVVCDNCNLPVIYGDTQRSVVLSDDNIENVAT SQNQNASNVPMPELEQVTPAQTTLNSEQQYAPHVISTPLAFLMRDALNSNIFGEPGWMGTGWRAGRDLKRKDIGGKTGTT NSSKDAWFSGYGPDTVTSVWIGFDDHRRNLGRSTASGAIPDQISGAEGGAKTAQPAWNDFMKVALEGLPEKQVPPPPGIV SVVIDKQTGKLSNGGPGSRSEYFIDGTQPTEHTVHEVGTTLMDNGQTHELF
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=851, Percent_Identity=77.9083431257344, Blast_Score=1415, Evalue=0.0, Organism=Escherichia coli, GI1786343, Length=248, Percent_Identity=35.8870967741936, Blast_Score=136, Evalue=5e-33, Organism=Escherichia coli, GI1788867, Length=205, Percent_Identity=38.0487804878049, Blast_Score=128, Evalue=1e-30, Organism=Escherichia coli, GI1789601, Length=177, Percent_Identity=37.2881355932203, Blast_Score=96, Evalue=1e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 93778; Mature: 93778
Theoretical pI: Translated: 7.38; Mature: 7.38
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKFVKYFLILAVCCILLGAASIFGLYKYIEPQLPDVATLKDIRLQTPMQVYSAEGELIAQ CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHH FGEKRRIPLTLNQIPPEMVHAFIATEDSRFYDHHGVDPVGILRAVSIAMLSGRASQGAST HCCCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHH ITQQLARNFFLSPERTLMRKIKEAFLAIRIEQMLTKDEILELYLNKIYLGYRAYGVGAAA HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHH QVYFGKEVHELTLSQIAMIAGLPKAPSTFNPLYSYDRAVARRNVVLLRMLDEKYITQAQY HHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEEEHHHHHHHHHHH DQARSEELVANYHVPQIAFSAPYLAEMVRQEMIKRYGENAYTDGYQVYTTITRKLQLAAV HHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHH DSLRANVLAYDMRHGYRGPSNVLWKVGESAWSREQIIDSLKALPVYGPLLPAVVTEADAA HHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHH QATAMLADGSNVTLPMVGIRWARPFKSDNAQGPVPKKATDVVQPGQQIWVRKVDDNWWLA HHEEEEECCCCCEEEEECCEECCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCEEEE QVPDVNSALVSIDPNNGAIKALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL ECCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCC TLATILNDLPITRWDSGAGTDWRPKNSPPTYDGPIRLRQGLGQSKNVVMVRAMRAMGVDY CHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEHHHHHHHHCHHH AAEYLQRFGFPAQNIVHSESLALGSASFTPLQLVRGYAVLANGGYLVDPYFITKITDDVG HHHHHHHCCCCHHHHHCCCHHCCCCCCCCHHHHHCCEEEEECCCEEECCEEEEHHHHHHH NVLFETKPKVVCDNCNLPVIYGDTQRSVVLSDDNIENVATSQNQNASNVPMPELEQVTPA HHHCCCCCCEEECCCCEEEEECCCCCEEEECCCCCHHHHCCCCCCCCCCCCCCHHHCCCH QTTLNSEQQYAPHVISTPLAFLMRDALNSNIFGEPGWMGTGWRAGRDLKRKDIGGKTGTT HHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCC NSSKDAWFSGYGPDTVTSVWIGFDDHRRNLGRSTASGAIPDQISGAEGGAKTAQPAWNDF CCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH MKVALEGLPEKQVPPPPGIVSVVIDKQTGKLSNGGPGSRSEYFIDGTQPTEHTVHEVGTT HHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHH LMDNGQTHELF HHCCCCCCCCC >Mature Secondary Structure MKFVKYFLILAVCCILLGAASIFGLYKYIEPQLPDVATLKDIRLQTPMQVYSAEGELIAQ CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHH FGEKRRIPLTLNQIPPEMVHAFIATEDSRFYDHHGVDPVGILRAVSIAMLSGRASQGAST HCCCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHH ITQQLARNFFLSPERTLMRKIKEAFLAIRIEQMLTKDEILELYLNKIYLGYRAYGVGAAA HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHH QVYFGKEVHELTLSQIAMIAGLPKAPSTFNPLYSYDRAVARRNVVLLRMLDEKYITQAQY HHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEEEHHHHHHHHHHH DQARSEELVANYHVPQIAFSAPYLAEMVRQEMIKRYGENAYTDGYQVYTTITRKLQLAAV HHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHH DSLRANVLAYDMRHGYRGPSNVLWKVGESAWSREQIIDSLKALPVYGPLLPAVVTEADAA HHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHH QATAMLADGSNVTLPMVGIRWARPFKSDNAQGPVPKKATDVVQPGQQIWVRKVDDNWWLA HHEEEEECCCCCEEEEECCEECCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCEEEE QVPDVNSALVSIDPNNGAIKALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL ECCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCC TLATILNDLPITRWDSGAGTDWRPKNSPPTYDGPIRLRQGLGQSKNVVMVRAMRAMGVDY CHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEHHHHHHHHCHHH AAEYLQRFGFPAQNIVHSESLALGSASFTPLQLVRGYAVLANGGYLVDPYFITKITDDVG HHHHHHHCCCCHHHHHCCCHHCCCCCCCCHHHHHCCEEEEECCCEEECCEEEEHHHHHHH NVLFETKPKVVCDNCNLPVIYGDTQRSVVLSDDNIENVATSQNQNASNVPMPELEQVTPA HHHCCCCCCEEECCCCEEEEECCCCCEEEECCCCCHHHHCCCCCCCCCCCCCCHHHCCCH QTTLNSEQQYAPHVISTPLAFLMRDALNSNIFGEPGWMGTGWRAGRDLKRKDIGGKTGTT HHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCC NSSKDAWFSGYGPDTVTSVWIGFDDHRRNLGRSTASGAIPDQISGAEGGAKTAQPAWNDF CCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH MKVALEGLPEKQVPPPPGIVSVVIDKQTGKLSNGGPGSRSEYFIDGTQPTEHTVHEVGTT HHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHH LMDNGQTHELF HHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 3882429; 9278503; 3920658; 7006606; 9841666 [H]