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The map label for this gene is aroA [H]

Identifier: 229137829

GI number: 229137829

Start: 2361809

End: 2363173

Strand: Reverse

Name: aroA [H]

Synonym: Nmul_A2071

Alternate gene names: 229137829

Gene position: 2363173-2361809 (Counterclockwise)

Preceding gene: 82703199

Following gene: 82703190

Centisome position: 74.21

GC content: 56.48

Gene sequence:

>1365_bases
GTGAAATTTATTGACTTGCCGGTAGTCGAGCGTGCTCGGGGTAGCGTTCGCTTGCCTGGCTCAAAGAGCATTTCCAATCG
AATTTTGTTACTTGCCGCGTTGTCGGAGGGGGTAACCGATGTTTGCGACCTCCTGGCTTCCGATGATACTGCCCGTATGC
TCGATGCCCTCTCCACTCTAGGTGTATCCATCCTTCAGATCGGTAGAGACCATTATCGCTTGCAGGGAGTGGGGGACCAG
TTTCCTCTTCGTTTACCTACAACGGAAGCGGATCTGTTTTTAGGGAACGCGGGTACCGTTTTCCGTCCATTGACGGCCAT
GCTGGCACTTGCTCAAGGGCACTACCGGCTGTCGGGTGTGCCGCGAATGCATGAACGCCCCATTGGCGACCTGGTCGATG
CCCTGCGTCAAGTAGGCGCGGATATCACCTATCTCGGGAAGGAAGGTTTCCCGCCGCTCCAGATCAAACCCGGGCGGATC
CATCCGGGGGAAATAACGGTAAGGGGCGAGGTATCGAGTCAGTTCCTCACTGCCCTGTTGATGGTGCTGCCTTTCCTGCG
CGCGGAAATGGATGAGTTACCGGTCATCACCGTGGCAGGGGAACTGATTTCGCGACCCTACATCGATCTTACCATCGCCT
TGATGGCGCGTTTTGGGGTACAGGTGGAGCGGGAGGAGTGGCGGCGCTTTACTGTACCCGCAGACCAGCGCTATCGGAGT
CCGGGTCAGGTATTCGTCGAGGGCGATGCGTCCTCAGCCTCCTATTTTCTTGCGGCCGGTGCAATCGGGAGAGGGCCCGT
ACGCGTCGAAGGCTTAGGGCGTGACAGTGTCCAGGGAGACATTCGCTTTGCCGAGGCGCTCGAGCGAATGGGAGCGGATA
TCAGATTTGGCGATAACTGGATCGAAGCAAGCGGTCCCGGACCGGGTGGCTTGCGAGCAATCGATCTGGACTGCAACCAT
ATTCCGGATGCGGCGATGACGCTTGCAGTGACAGCCTTGTTCGCGCGGGGAAACACCGTTCTCAGGAATATCGCGAGCTG
GCGGGTAAAGGAAACCGATCGTATTGCAGCCATGGCGCAGGAATTGCGCAAACTCGGCGCAGAAGTGGAGGCAGGGTCCG
ATTTTCTGCAAATCAGCCCGCCTCGCGGGGAACTGGTGGCGAATGCGGCTATTGATACCTATGATGATCATCGCATGGCA
ATGTGCTTTTCCCTGGTGTCTTTTGGCGCGCCGGTTCGAATCAATGATCCCCGGTGTGTCTCAAAGACGTTTCCCGATTA
TTTTGAAAAATTTGCGGCTATCGCCTATGCCGATCCAGGGCAGGGTAAATTCGCTGCCCGGATCGATTCTTCTGATATTT
CATGA

Upstream 100 bases:

>100_bases
AATTGGAGGTCGATTATAATAGCCGGTTTTATCGTCGAACTGGCTGTTTATCGATGAAGGCAATCTTGTTTATCGATGAA
GGCAATCTCCAAGGCAGCGC

Downstream 100 bases:

>100_bases
ACGATAAGACTATTCAGGATATTCCCGTCATCGCGATTGACGGTCCTTCTGCTTCCGGCAAGGGCACCGTAGCGCAACGG
GTCGCCGCAAAACTCGGCTT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKFIDLPVVERARGSVRLPGSKSISNRILLLAALSEGVTDVCDLLASDDTARMLDALSTLGVSILQIGRDHYRLQGVGDQ
FPLRLPTTEADLFLGNAGTVFRPLTAMLALAQGHYRLSGVPRMHERPIGDLVDALRQVGADITYLGKEGFPPLQIKPGRI
HPGEITVRGEVSSQFLTALLMVLPFLRAEMDELPVITVAGELISRPYIDLTIALMARFGVQVEREEWRRFTVPADQRYRS
PGQVFVEGDASSASYFLAAGAIGRGPVRVEGLGRDSVQGDIRFAEALERMGADIRFGDNWIEASGPGPGGLRAIDLDCNH
IPDAAMTLAVTALFARGNTVLRNIASWRVKETDRIAAMAQELRKLGAEVEAGSDFLQISPPRGELVANAAIDTYDDHRMA
MCFSLVSFGAPVRINDPRCVSKTFPDYFEKFAAIAYADPGQGKFAARIDSSDIS

Sequences:

>Translated_454_residues
MKFIDLPVVERARGSVRLPGSKSISNRILLLAALSEGVTDVCDLLASDDTARMLDALSTLGVSILQIGRDHYRLQGVGDQ
FPLRLPTTEADLFLGNAGTVFRPLTAMLALAQGHYRLSGVPRMHERPIGDLVDALRQVGADITYLGKEGFPPLQIKPGRI
HPGEITVRGEVSSQFLTALLMVLPFLRAEMDELPVITVAGELISRPYIDLTIALMARFGVQVEREEWRRFTVPADQRYRS
PGQVFVEGDASSASYFLAAGAIGRGPVRVEGLGRDSVQGDIRFAEALERMGADIRFGDNWIEASGPGPGGLRAIDLDCNH
IPDAAMTLAVTALFARGNTVLRNIASWRVKETDRIAAMAQELRKLGAEVEAGSDFLQISPPRGELVANAAIDTYDDHRMA
MCFSLVSFGAPVRINDPRCVSKTFPDYFEKFAAIAYADPGQGKFAARIDSSDIS
>Mature_454_residues
MKFIDLPVVERARGSVRLPGSKSISNRILLLAALSEGVTDVCDLLASDDTARMLDALSTLGVSILQIGRDHYRLQGVGDQ
FPLRLPTTEADLFLGNAGTVFRPLTAMLALAQGHYRLSGVPRMHERPIGDLVDALRQVGADITYLGKEGFPPLQIKPGRI
HPGEITVRGEVSSQFLTALLMVLPFLRAEMDELPVITVAGELISRPYIDLTIALMARFGVQVEREEWRRFTVPADQRYRS
PGQVFVEGDASSASYFLAAGAIGRGPVRVEGLGRDSVQGDIRFAEALERMGADIRFGDNWIEASGPGPGGLRAIDLDCNH
IPDAAMTLAVTALFARGNTVLRNIASWRVKETDRIAAMAQELRKLGAEVEAGSDFLQISPPRGELVANAAIDTYDDHRMA
MCFSLVSFGAPVRINDPRCVSKTFPDYFEKFAAIAYADPGQGKFAARIDSSDIS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=438, Percent_Identity=55.2511415525114, Blast_Score=442, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6320332, Length=472, Percent_Identity=36.0169491525424, Blast_Score=225, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 49371; Mature: 49371

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDLPVVERARGSVRLPGSKSISNRILLLAALSEGVTDVCDLLASDDTARMLDALSTL
CCEECCCHHHHCCCCEECCCCCCCCCCEEEEEEHHCCHHHHHHHHCCCCHHHHHHHHHHH
GVSILQIGRDHYRLQGVGDQFPLRLPTTEADLFLGNAGTVFRPLTAMLALAQGHYRLSGV
HHHHHHHCCHHEEEECCCCCCCEECCCCCCCEEECCCCHHHHHHHHHHHHHCCCEEECCC
PRMHERPIGDLVDALRQVGADITYLGKEGFPPLQIKPGRIHPGEITVRGEVSSQFLTALL
CCHHCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCCCEEEECCHHHHHHHHHH
MVLPFLRAEMDELPVITVAGELISRPYIDLTIALMARFGVQVEREEWRRFTVPADQRYRS
HHHHHHHHHHHHCCEEEEEHHHHCCCHHHHHHHHHHHHCCEEEHHHCCEECCCHHHHCCC
PGQVFVEGDASSASYFLAAGAIGRGPVRVEGLGRDSVQGDIRFAEALERMGADIRFGDNW
CCCEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEECCCE
IEASGPGPGGLRAIDLDCNHIPDAAMTLAVTALFARGNTVLRNIASWRVKETDRIAAMAQ
EECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHH
ELRKLGAEVEAGSDFLQISPPRGELVANAAIDTYDDHRMAMCFSLVSFGAPVRINDPRCV
HHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEECCCCHH
SKTFPDYFEKFAAIAYADPGQGKFAARIDSSDIS
HHCCHHHHHHHHHEEECCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MKFIDLPVVERARGSVRLPGSKSISNRILLLAALSEGVTDVCDLLASDDTARMLDALSTL
CCEECCCHHHHCCCCEECCCCCCCCCCEEEEEEHHCCHHHHHHHHCCCCHHHHHHHHHHH
GVSILQIGRDHYRLQGVGDQFPLRLPTTEADLFLGNAGTVFRPLTAMLALAQGHYRLSGV
HHHHHHHCCHHEEEECCCCCCCEECCCCCCCEEECCCCHHHHHHHHHHHHHCCCEEECCC
PRMHERPIGDLVDALRQVGADITYLGKEGFPPLQIKPGRIHPGEITVRGEVSSQFLTALL
CCHHCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCCCEEEECCHHHHHHHHHH
MVLPFLRAEMDELPVITVAGELISRPYIDLTIALMARFGVQVEREEWRRFTVPADQRYRS
HHHHHHHHHHHHCCEEEEEHHHHCCCHHHHHHHHHHHHCCEEEHHHCCEECCCHHHHCCC
PGQVFVEGDASSASYFLAAGAIGRGPVRVEGLGRDSVQGDIRFAEALERMGADIRFGDNW
CCCEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEECCCE
IEASGPGPGGLRAIDLDCNHIPDAAMTLAVTALFARGNTVLRNIASWRVKETDRIAAMAQ
EECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHH
ELRKLGAEVEAGSDFLQISPPRGELVANAAIDTYDDHRMAMCFSLVSFGAPVRINDPRCV
HHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEECCCCHH
SKTFPDYFEKFAAIAYADPGQGKFAARIDSSDIS
HHCCHHHHHHHHHEEECCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]