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The map label for this gene is luxS [H]

Identifier: 228995275

GI number: 228995275

Start: 1361763

End: 1362335

Strand: Direct

Name: luxS [H]

Synonym: SPy_1642

Alternate gene names: 228995275

Gene position: 1361763-1362335 (Clockwise)

Preceding gene: 15675514

Following gene: 15675520

Centisome position: 73.51

GC content: 40.49

Gene sequence:

>573_bases
TTGATCTGTTTTCTTAGCCTTTTCTCCTCCACAAGTAGCCACTTTCTCACTATTTGTGTTATGATAAAGTGTAAAACAAA
GGAGATTGAAATGACAAAAGAAGTTATCGTCGAAAGTTTTGAGCTAGATCATACTATTGTAAAGGCCCCTTATGTTCGTC
TTATTTCTGAAGAATTTGGACCCAAGGGCGATCGTATTACAAATTTTGATGTTCGCCTAGTGCAGCCTAACCAAAATTCT
ATTGAAACAGCCGGTTTGCATACCATTGAACACTTACTTGCCAAGCTCATCCGCCAACGCATTGATGGGATGATTGATTG
CTCTCCTTTTGGCTGTCGAACAGGTTTTCACCTTATCATGTGGGGAAAACACAGTTCTACTGATATTGCCAAGGTGATTA
AATCCAGCCTAGAAGAAATTGCAACTGGGATTACTTGGGAAGATGTTCCTGGAACAACTCTTGAATCCTGTGGGAACTAT
AAGGATCATAGCCTCTTTGCCGCCAAAGAATGGGCTCAATTGATTATTGATCAAGGGATTTCAGACGATCCTTTTAGTCG
CCATGTCATCTGA

Upstream 100 bases:

>100_bases
TTCTTAGCATTGACAGGACTTAACCACAAAAATGCTTTTAAAGAAACCTTTATTACTGTTTCTGTAAGTACTTTTATCGC
ACAGGTCATTGTGATAGCCT

Downstream 100 bases:

>100_bases
TACTAGTGTGTTGTCAAACATAACAATCCTACTGACCTATTTGACTTGTTACAAAAAACAAGTCTATCTGCAGATTTTAA
GACAACATACTTTATTAATC

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MICFLSLFSSTSSHFLTICVMIKCKTKEIEMTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLVQPNQNS
IETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNY
KDHSLFAAKEWAQLIIDQGISDDPFSRHVI

Sequences:

>Translated_190_residues
MICFLSLFSSTSSHFLTICVMIKCKTKEIEMTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLVQPNQNS
IETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNY
KDHSLFAAKEWAQLIIDQGISDDPFSRHVI
>Mature_190_residues
MICFLSLFSSTSSHFLTICVMIKCKTKEIEMTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLVQPNQNS
IETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNY
KDHSLFAAKEWAQLIIDQGISDDPFSRHVI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=149, Percent_Identity=34.8993288590604, Blast_Score=107, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 21402; Mature: 21402

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICFLSLFSSTSSHFLTICVMIKCKTKEIEMTKEVIVESFELDHTIVKAPYVRLISEEFG
CEEEEEECCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
PKGDRITNFDVRLVQPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIM
CCCCCEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCEEEE
WGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGI
ECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCC
SDDPFSRHVI
CCCCCCCCCC
>Mature Secondary Structure
MICFLSLFSSTSSHFLTICVMIKCKTKEIEMTKEVIVESFELDHTIVKAPYVRLISEEFG
CEEEEEECCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
PKGDRITNFDVRLVQPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIM
CCCCCEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCEEEE
WGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGI
ECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCC
SDDPFSRHVI
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA