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The map label for this gene is engA

Identifier: 227815649

GI number: 227815649

Start: 2796642

End: 2797952

Strand: Reverse

Name: engA

Synonym: BAMEG_3068

Alternate gene names: 227815649

Gene position: 2797952-2796642 (Counterclockwise)

Preceding gene: 227815650

Following gene: 227815648

Centisome position: 53.5

GC content: 38.22

Gene sequence:

>1311_bases
ATGCCGAAACCAGTAATAGCAATAGTAGGCCGCCCGAACGTAGGGAAATCTACTATTTTCAATAGAATTGTTGGAGAGAG
AGTTTCAATCGTAGAAGATATTCCAGGTGTAACGCGCGATCGTATTTATAGCGCTGGAGAATGGTTAAATCATGAATTTA
ACATTATTGATACAGGTGGAATTGATATTGGAGACGAGCCATTTTTGACACAAATTCGTCAACAAGCTGAAGTAGCAATT
GATGAAGCAGATGTTATCATTTTTATGACAAATGGTCGTGACGGTGTAACAGCAGCGGATGAAGAAGTTGCAAAAATATT
ATATCGTTCAAATAAACCAGTTGTACTTGCAGTAAATAAAGTGGACAATCCGGAAATGCGCAGTGACATTTATGATTTCT
ATGCATTAGGATTTGGCGAGCCATTCCCAATCTCAGGTACACACGGATTAGGATTAGGTGACTTATTAGATGAAGCTGCA
CAGCATTTTCCAAAGATTGAAGAAGACGGATATGATGAAGATACAATTCGTTTCTCTTTAATTGGCCGTCCAAATGTAGG
GAAATCATCACTTGTAAATGCTCTTCTTGGTCAAGAGCGTGTAATTGTTAGTAATGTAGCAGGAACAACTCGTGATGCTG
TCGATACACCATATAGTAAAGATGGAAAAGATTATGTAATTATCGATACAGCTGGTATGCGTAAAAAAGGGAAAGTGTAT
GAAAGTACAGAAAAGTATAGTGTACTTCGTGCACTAAGAGCGATTGAACGTTCTGACGTTGTTTTAGTCGTTTTAGACGG
TGAAGAAGGAATTATTGAACAAGATAAAAAAATCGCTGGATACGCTCATGATTCAGGACGAGCTGTCGTGATCGTTGTAA
ACAAATGGGACGCAGTGAAAAAAGATGAGAAAACAATGAAAGCATTTGAAGAAAACATTCGTGCTCATTTCCAATTTTTA
GAGTACGCACCGATTGTATTCTTATCTGCAAAAACGAGAAAACGTACACAAACGTTAATACCGGTTATCGATGAGGTAAA
TGAAAGCCATAGTATCCGTATTCAAACGAATGTATTAAATGATGTAATTATGGATGCGGTAGCGATGAATCCAACGCCAA
CGCATAACGGTAGTCGTCTGAAGATTTTCTATGCAACACAAGTTGCGGTAAAACCACCAACATTTGTTGTGTTTGTAAAC
GATCCAGAACTATTGCACTTCTCATATGAGCGCTTCTTAAAAAATCGTTTACGTGAATCATTCGGCTTTGTAGGAACGCC
GATTCACATTATCGCTAGAGCAAGAGACTAA

Upstream 100 bases:

>100_bases
TTTTGATACGCTGAGAAATATTCTGGAATGCAAAACCCTTCTTGCACAAAGAAGGGTTTTTTACATAATAAACAGAAGCA
AGTTGAAAGGATGAAAGTAT

Downstream 100 bases:

>100_bases
TGGAGAGGATGTGATTTTATGACAAAAATCACAGTAGTTGGAGCAGGTAGCTGGGGAACAGCGTTAGCGATGGTATTAGC
TGACAATGGGCATGATGTAC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MPKPVIAIVGRPNVGKSTIFNRIVGERVSIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGGIDIGDEPFLTQIRQQAEVAI
DEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNKVDNPEMRSDIYDFYALGFGEPFPISGTHGLGLGDLLDEAA
QHFPKIEEDGYDEDTIRFSLIGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYSKDGKDYVIIDTAGMRKKGKVY
ESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVKKDEKTMKAFEENIRAHFQFL
EYAPIVFLSAKTRKRTQTLIPVIDEVNESHSIRIQTNVLNDVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVN
DPELLHFSYERFLKNRLRESFGFVGTPIHIIARARD

Sequences:

>Translated_436_residues
MPKPVIAIVGRPNVGKSTIFNRIVGERVSIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGGIDIGDEPFLTQIRQQAEVAI
DEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNKVDNPEMRSDIYDFYALGFGEPFPISGTHGLGLGDLLDEAA
QHFPKIEEDGYDEDTIRFSLIGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYSKDGKDYVIIDTAGMRKKGKVY
ESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVKKDEKTMKAFEENIRAHFQFL
EYAPIVFLSAKTRKRTQTLIPVIDEVNESHSIRIQTNVLNDVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVN
DPELLHFSYERFLKNRLRESFGFVGTPIHIIARARD
>Mature_435_residues
PKPVIAIVGRPNVGKSTIFNRIVGERVSIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGGIDIGDEPFLTQIRQQAEVAID
EADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNKVDNPEMRSDIYDFYALGFGEPFPISGTHGLGLGDLLDEAAQ
HFPKIEEDGYDEDTIRFSLIGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYSKDGKDYVIIDTAGMRKKGKVYE
STEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVKKDEKTMKAFEENIRAHFQFLE
YAPIVFLSAKTRKRTQTLIPVIDEVNESHSIRIQTNVLNDVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVND
PELLHFSYERFLKNRLRESFGFVGTPIHIIARARD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=40, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1788919, Length=186, Percent_Identity=33.8709677419355, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=44.5652173913043, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323665, Length=204, Percent_Identity=32.843137254902, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45550813, Length=191, Percent_Identity=30.8900523560209, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_BACAA (C3P591)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002866007.1
- ProteinModelPortal:   C3P591
- SMR:   C3P591
- EnsemblBacteria:   EBBACT00000129209
- GeneID:   7849654
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1594
- GeneTree:   EBGT00070000032012
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 48619; Mature: 48488

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPVIAIVGRPNVGKSTIFNRIVGERVSIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHCCCEEEEEECCC
IDIGDEPFLTQIRQQAEVAIDEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNK
CCCCCCHHHHHHHHHHHHEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEC
VDNPEMRSDIYDFYALGFGEPFPISGTHGLGLGDLLDEAAQHFPKIEEDGYDEDTIRFSL
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYSKDGKDYVIIDTAGMRKKGKVY
ECCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCCCCCEEEEEECCCCCCCCCCH
ESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVK
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCEEEEEEECCCCEEEEEEECCCCCC
KDEKTMKAFEENIRAHFQFLEYAPIVFLSAKTRKRTQTLIPVIDEVNESHSIRIQTNVLN
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEHHHHH
DVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVNDPELLHFSYERFLKNRLRES
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCEEHHHHHHHHHHHHHHH
FGFVGTPIHIIARARD
HCCCCCCEEEEEECCC
>Mature Secondary Structure 
PKPVIAIVGRPNVGKSTIFNRIVGERVSIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGG
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHCCCEEEEEECCC
IDIGDEPFLTQIRQQAEVAIDEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNK
CCCCCCHHHHHHHHHHHHEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEC
VDNPEMRSDIYDFYALGFGEPFPISGTHGLGLGDLLDEAAQHFPKIEEDGYDEDTIRFSL
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYSKDGKDYVIIDTAGMRKKGKVY
ECCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCCCCCEEEEEECCCCCCCCCCH
ESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVK
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCEEEEEEECCCCEEEEEEECCCCCC
KDEKTMKAFEENIRAHFQFLEYAPIVFLSAKTRKRTQTLIPVIDEVNESHSIRIQTNVLN
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEHHHHH
DVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVNDPELLHFSYERFLKNRLRES
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCEEHHHHHHHHHHHHHHH
FGFVGTPIHIIARARD
HCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA