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The map label for this gene is yjjG [H]

Identifier: 227814467

GI number: 227814467

Start: 1711036

End: 1711728

Strand: Direct

Name: yjjG [H]

Synonym: BAMEG_1875

Alternate gene names: 227814467

Gene position: 1711036-1711728 (Clockwise)

Preceding gene: 227814462

Following gene: 227814468

Centisome position: 32.72

GC content: 30.88

Gene sequence:

>693_bases
ATGGGTTATAAAGCTATGCTGTTTGATTTAGATGATACGTTACTTAATAGGGATAAAGCAGTAGATAATCTGTTTTTATT
ACTTTTTGAAAAGTGTTATGAGGATGTTAGTGATACAATCAAAAACAATATGCTACAGAAATTCAAAGAATTTGATAAAA
GAGAATATGGCATGAGTGATAAAACGATAGTATTAGAATCATTATTTGATGAATTCGCGCCGAGGTATAGATTGCCACGC
AATTATATCCAAGATTTTTGGAATGAAAACTTCCCAAAATGTTTTTCAATAGACCAGAATACTATCCATTTCTTAAATCA
TATAAAGAAGCACTTTGAAGTTGGAATTATAACAAATGGCTCAACGCAGAGGCAAAAGGCTAAAATAATTAACACACATT
TAAACAATTACTTTGATACGATCATTATTTCTGAAGAAGTGGGATTTAGTAAACCGGATAAACGTATATTCGAACTAGCA
TTAAATAAGCTAAATGTACAGCCGGAAAATACTTTATTTGTTGGGGATGACATAGAAAAGGATATTGCTGGTCCTCAAAA
TGCAAATATAAAAGGTGTGTGGTTTAACCCTCAGAAAATTAAGAATACTACCAAAATACAACCATATGCCGAGATTAACA
CTTTGGATAGCTTGTTAAGTTATGTTACGCCACAATATTTTTTTAACAAGTAA

Upstream 100 bases:

>100_bases
CTCTTAGAATATCATTCTATTACGAGTTCTTTGATATGAATTGTGTTGTGATTACTTTTGATGATAACTAGGAAATATAG
AAAGGTTGTGAAGTTATTTG

Downstream 100 bases:

>100_bases
AATTAATTTCATTGACCGTATTAGTAATAAAAAATAGAGGCGATTTTAATAGCTGCGGCTAATTTAATCTATGATTAATA
CGAAGTTTTGTAAAACAATT

Product: hydrolase, haloacid dehalogenase-like family

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MGYKAMLFDLDDTLLNRDKAVDNLFLLLFEKCYEDVSDTIKNNMLQKFKEFDKREYGMSDKTIVLESLFDEFAPRYRLPR
NYIQDFWNENFPKCFSIDQNTIHFLNHIKKHFEVGIITNGSTQRQKAKIINTHLNNYFDTIIISEEVGFSKPDKRIFELA
LNKLNVQPENTLFVGDDIEKDIAGPQNANIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYFFNK

Sequences:

>Translated_230_residues
MGYKAMLFDLDDTLLNRDKAVDNLFLLLFEKCYEDVSDTIKNNMLQKFKEFDKREYGMSDKTIVLESLFDEFAPRYRLPR
NYIQDFWNENFPKCFSIDQNTIHFLNHIKKHFEVGIITNGSTQRQKAKIINTHLNNYFDTIIISEEVGFSKPDKRIFELA
LNKLNVQPENTLFVGDDIEKDIAGPQNANIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYFFNK
>Mature_229_residues
GYKAMLFDLDDTLLNRDKAVDNLFLLLFEKCYEDVSDTIKNNMLQKFKEFDKREYGMSDKTIVLESLFDEFAPRYRLPRN
YIQDFWNENFPKCFSIDQNTIHFLNHIKKHFEVGIITNGSTQRQKAKIINTHLNNYFDTIIISEEVGFSKPDKRIFELAL
NKLNVQPENTLFVGDDIEKDIAGPQNANIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYFFNK

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Homo sapiens, GI23308749, Length=210, Percent_Identity=27.6190476190476, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1790833, Length=225, Percent_Identity=28.8888888888889, Blast_Score=93, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28571108, Length=202, Percent_Identity=25.7425742574257, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 27048; Mature: 26917

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYKAMLFDLDDTLLNRDKAVDNLFLLLFEKCYEDVSDTIKNNMLQKFKEFDKREYGMSD
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KTIVLESLFDEFAPRYRLPRNYIQDFWNENFPKCFSIDQNTIHFLNHIKKHFEVGIITNG
HHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHEEEEEECC
STQRQKAKIINTHLNNYFDTIIISEEVGFSKPDKRIFELALNKLNVQPENTLFVGDDIEK
CCHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCHHH
DIAGPQNANIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYFFNK
HCCCCCCCCEEEEEECHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure 
GYKAMLFDLDDTLLNRDKAVDNLFLLLFEKCYEDVSDTIKNNMLQKFKEFDKREYGMSD
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KTIVLESLFDEFAPRYRLPRNYIQDFWNENFPKCFSIDQNTIHFLNHIKKHFEVGIITNG
HHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHEEEEEECC
STQRQKAKIINTHLNNYFDTIIISEEVGFSKPDKRIFELALNKLNVQPENTLFVGDDIEK
CCHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCHHH
DIAGPQNANIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYFFNK
HCCCCCCCCEEEEEECHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]