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The map label for this gene is ddc [H]

Identifier: 227814462

GI number: 227814462

Start: 1706353

End: 1707807

Strand: Direct

Name: ddc [H]

Synonym: BAMEG_1870

Alternate gene names: 227814462

Gene position: 1706353-1707807 (Clockwise)

Preceding gene: 227814461

Following gene: 227814467

Centisome position: 32.63

GC content: 35.12

Gene sequence:

>1455_bases
ATGACAAAAAACTTGCAGTTATCAGCCGAAGAGATGCGTCAGTTAGGATATCAAGCGGTTGACTTGATTGTTGATCATAT
GAATCATTTAAAAAGTAAACCAGTTTCAGAAACGATTGATAGTAATATTTTTAGAGACAAGCTAATTGAAACGATTCCGG
AAAACGGATCTAATCCAAAAGAATTACTTCATTTTCTTAATAACAATGTGTTTAATCAAATTACTCATGTGGATCATCCT
CATTTTATGGCTTTTGTACCAGGTCCTAATAATTATGTTGGTGTATTAGCAGATTTTTTAGCAAGTGGGTTTAATGTATT
TCCTACAGCTTGGATAGTAGGTGCAGGTGCCGAACAAATTGAATTAACGACAATTAACTGGTTAAAATCAATGCTAGGAT
TCCCTGATTCAGCTGAAGGACTGTTTGTCAGTGGTGGTTCCATGGCTAATTTGACTGCACTTACTGTAGCGAGACAGGTT
AAGTTGAATAATGAAATCGAAAATGCGATTGTTTATTTTTCTAACCAAACTCATTTTTCTGTAGATCGAGCGCTTAAAGT
ATTAGGTTTTAAACAGCATCAAATTTGCCGAATTGAGACAGATGAAGATTTAAAAATTTCAGTTAGTACTTTAAGAAAGC
AAATAAAAGAAGATCGATTAAAAGGGAAAAAACCATTTTGTGTTATTGCGAATGCAGGGACAACGAATTGCGGAGCGGTG
GACTCCCTCGATGAATTGGCTGATCTATGTGGTGATGAAGATATATGGTTACACGCGGATGGGGCTTATGGAGCTGCAGC
AATTCTCAGCGAAAAAGGAAGAGAGTTGTTAAGAGGAATTCATCGTGTTGATTCTTTGACATTAGATCCGCATAAATGGC
TTTTTCAGCCTTATGATGTTGGTTGTGTACTCATTCGAAATAGTCAATATTTAAGTGAAACGTTTCGTATGATCCCAGAG
TATATTAGGGATACGGAAACTAATATAGAAGAAAAAGTGAATTTTGGAGAGCGTGGAATTGAACTTTCTCGTAGATTTAG
AGCATTAAAGGTATGGCTTTCTTTTAAAGCATTTGGAGTTACAGCTTTTCGCGAGGCAATTGATCATGGCATTATGCTAG
CTGAACAAGTTGAAGAGTTTTTAAGGAAAGAAAAAGATTGGGAAGTAGTAACACCTGCCCAATTAGGAATTGTTACTTTT
CGTTATATTCCATGTGAGCTAACATCTACAGATACAATTCATGAAATAAACAAAAAATTGGTGGAAGAAATTAATCAAAG
AGGATTTGCTATGCTAAGTACGACTAAATTAAAAGAAAAAGTAGTAATTCGACTTTGCTCTATCAACCCAAGGACAACAA
AAGAAGAAATACTTCAAATCATGATGAACATAAAAGTATTGGCAGAGGAAATAAACACAACGTCTAAACATCTTATATCT
GTTCCTCAACCTTGA

Upstream 100 bases:

>100_bases
ATTCTTCAAAATCCAATACAAGCAATTGGTGATTACAAATTATAAAAAATGAAAAGGCGAGCAAGAACTCGCCTTTTTAA
ATAGAATAGGAGTAAACCAA

Downstream 100 bases:

>100_bases
TATAATAGGCGGATTTTAAATATAATAGCCGATTTCAAATAAGAATCGGCTATTATATTTAAATGATAATAACACTCACC
AATGTATACTATTTATGAGT

Product: decarboxylase, pyridoxal-dependent

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MTKNLQLSAEEMRQLGYQAVDLIVDHMNHLKSKPVSETIDSNIFRDKLIETIPENGSNPKELLHFLNNNVFNQITHVDHP
HFMAFVPGPNNYVGVLADFLASGFNVFPTAWIVGAGAEQIELTTINWLKSMLGFPDSAEGLFVSGGSMANLTALTVARQV
KLNNEIENAIVYFSNQTHFSVDRALKVLGFKQHQICRIETDEDLKISVSTLRKQIKEDRLKGKKPFCVIANAGTTNCGAV
DSLDELADLCGDEDIWLHADGAYGAAAILSEKGRELLRGIHRVDSLTLDPHKWLFQPYDVGCVLIRNSQYLSETFRMIPE
YIRDTETNIEEKVNFGERGIELSRRFRALKVWLSFKAFGVTAFREAIDHGIMLAEQVEEFLRKEKDWEVVTPAQLGIVTF
RYIPCELTSTDTIHEINKKLVEEINQRGFAMLSTTKLKEKVVIRLCSINPRTTKEEILQIMMNIKVLAEEINTTSKHLIS
VPQP

Sequences:

>Translated_484_residues
MTKNLQLSAEEMRQLGYQAVDLIVDHMNHLKSKPVSETIDSNIFRDKLIETIPENGSNPKELLHFLNNNVFNQITHVDHP
HFMAFVPGPNNYVGVLADFLASGFNVFPTAWIVGAGAEQIELTTINWLKSMLGFPDSAEGLFVSGGSMANLTALTVARQV
KLNNEIENAIVYFSNQTHFSVDRALKVLGFKQHQICRIETDEDLKISVSTLRKQIKEDRLKGKKPFCVIANAGTTNCGAV
DSLDELADLCGDEDIWLHADGAYGAAAILSEKGRELLRGIHRVDSLTLDPHKWLFQPYDVGCVLIRNSQYLSETFRMIPE
YIRDTETNIEEKVNFGERGIELSRRFRALKVWLSFKAFGVTAFREAIDHGIMLAEQVEEFLRKEKDWEVVTPAQLGIVTF
RYIPCELTSTDTIHEINKKLVEEINQRGFAMLSTTKLKEKVVIRLCSINPRTTKEEILQIMMNIKVLAEEINTTSKHLIS
VPQP
>Mature_483_residues
TKNLQLSAEEMRQLGYQAVDLIVDHMNHLKSKPVSETIDSNIFRDKLIETIPENGSNPKELLHFLNNNVFNQITHVDHPH
FMAFVPGPNNYVGVLADFLASGFNVFPTAWIVGAGAEQIELTTINWLKSMLGFPDSAEGLFVSGGSMANLTALTVARQVK
LNNEIENAIVYFSNQTHFSVDRALKVLGFKQHQICRIETDEDLKISVSTLRKQIKEDRLKGKKPFCVIANAGTTNCGAVD
SLDELADLCGDEDIWLHADGAYGAAAILSEKGRELLRGIHRVDSLTLDPHKWLFQPYDVGCVLIRNSQYLSETFRMIPEY
IRDTETNIEEKVNFGERGIELSRRFRALKVWLSFKAFGVTAFREAIDHGIMLAEQVEEFLRKEKDWEVVTPAQLGIVTFR
YIPCELTSTDTIHEINKKLVEEINQRGFAMLSTTKLKEKVVIRLCSINPRTTKEEILQIMMNIKVLAEEINTTSKHLISV
PQP

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI92110055, Length=499, Percent_Identity=28.0561122244489, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI4503281, Length=485, Percent_Identity=26.1855670103093, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI132814448, Length=485, Percent_Identity=26.1855670103093, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI197383062, Length=434, Percent_Identity=27.1889400921659, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI197276620, Length=412, Percent_Identity=27.6699029126214, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4503875, Length=412, Percent_Identity=27.6699029126214, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI58331246, Length=412, Percent_Identity=25.7281553398058, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI194294551, Length=309, Percent_Identity=27.831715210356, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17534817, Length=494, Percent_Identity=26.9230769230769, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17534819, Length=494, Percent_Identity=26.9230769230769, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71981211, Length=523, Percent_Identity=23.1357552581262, Blast_Score=168, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI71981217, Length=532, Percent_Identity=22.7443609022556, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI133931025, Length=477, Percent_Identity=23.8993710691824, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17551992, Length=507, Percent_Identity=22.6824457593688, Blast_Score=148, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17555682, Length=426, Percent_Identity=24.8826291079812, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI71993062, Length=410, Percent_Identity=24.6341463414634, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71993058, Length=364, Percent_Identity=25.5494505494505, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24652373, Length=490, Percent_Identity=30.4081632653061, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI28573972, Length=486, Percent_Identity=28.8065843621399, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24586044, Length=473, Percent_Identity=25.7928118393235, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI17136190, Length=415, Percent_Identity=28.6746987951807, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24585135, Length=412, Percent_Identity=27.4271844660194, Blast_Score=191, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24585139, Length=490, Percent_Identity=25.1020408163265, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI221476190, Length=487, Percent_Identity=25.2566735112936, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24585143, Length=487, Percent_Identity=25.2566735112936, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI17136594, Length=436, Percent_Identity=25.4587155963303, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21356415, Length=395, Percent_Identity=25.5696202531646, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24657193, Length=339, Percent_Identity=25.3687315634218, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24657185, Length=339, Percent_Identity=25.3687315634218, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24657188, Length=339, Percent_Identity=25.3687315634218, Blast_Score=134, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 54703; Mature: 54572

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNLQLSAEEMRQLGYQAVDLIVDHMNHLKSKPVSETIDSNIFRDKLIETIPENGSNPK
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHH
ELLHFLNNNVFNQITHVDHPHFMAFVPGPNNYVGVLADFLASGFNVFPTAWIVGAGAEQI
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCEE
ELTTINWLKSMLGFPDSAEGLFVSGGSMANLTALTVARQVKLNNEIENAIVYFSNQTHFS
EEHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
VDRALKVLGFKQHQICRIETDEDLKISVSTLRKQIKEDRLKGKKPFCVIANAGTTNCGAV
HHHHHHHHCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
DSLDELADLCGDEDIWLHADGAYGAAAILSEKGRELLRGIHRVDSLTLDPHKWLFQPYDV
CCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCC
GCVLIRNSQYLSETFRMIPEYIRDTETNIEEKVNFGERGIELSRRFRALKVWLSFKAFGV
CEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TAFREAIDHGIMLAEQVEEFLRKEKDWEVVTPAQLGIVTFRYIPCELTSTDTIHEINKKL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHCEEEEEEEEEECCCCHHHHHHHHHH
VEEINQRGFAMLSTTKLKEKVVIRLCSINPRTTKEEILQIMMNIKVLAEEINTTSKHLIS
HHHHHHCCEEEEHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEE
VPQP
CCCC
>Mature Secondary Structure 
TKNLQLSAEEMRQLGYQAVDLIVDHMNHLKSKPVSETIDSNIFRDKLIETIPENGSNPK
CCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHH
ELLHFLNNNVFNQITHVDHPHFMAFVPGPNNYVGVLADFLASGFNVFPTAWIVGAGAEQI
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCEE
ELTTINWLKSMLGFPDSAEGLFVSGGSMANLTALTVARQVKLNNEIENAIVYFSNQTHFS
EEHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
VDRALKVLGFKQHQICRIETDEDLKISVSTLRKQIKEDRLKGKKPFCVIANAGTTNCGAV
HHHHHHHHCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
DSLDELADLCGDEDIWLHADGAYGAAAILSEKGRELLRGIHRVDSLTLDPHKWLFQPYDV
CCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCC
GCVLIRNSQYLSETFRMIPEYIRDTETNIEEKVNFGERGIELSRRFRALKVWLSFKAFGV
CEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TAFREAIDHGIMLAEQVEEFLRKEKDWEVVTPAQLGIVTFRYIPCELTSTDTIHEINKKL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHCEEEEEEEEEECCCCHHHHHHHHHH
VEEINQRGFAMLSTTKLKEKVVIRLCSINPRTTKEEILQIMMNIKVLAEEINTTSKHLIS
HHHHHHCCEEEEHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEE
VPQP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]