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The map label for this gene is glmM [H]

Identifier: 227080792

GI number: 227080792

Start: 600263

End: 601675

Strand: Reverse

Name: glmM [H]

Synonym: VCM66_0569

Alternate gene names: 227080792

Gene position: 601675-600263 (Counterclockwise)

Preceding gene: 227080793

Following gene: 227080780

Centisome position: 20.8

GC content: 49.19

Gene sequence:

>1413_bases
ATGATTAAATTTGGTACTGGCGGCTGGCGTGCGTTTATTGGTGAAGAATTCACTAAAGATAATGTGCGCTTGGTGGCTCA
AGCGTTAGCCAACATCATCCATCATGAACAAGCCGCAAACGAAGGCTTCGTAATTGGTTACGACCGCCGTTTTCTGTCAG
ACAAAGCGGGACGCTGGTTTGCCGAAGTGTTAGCCGCGAATGGCGTTGTGGTGAGCTTTATCGACAAGTTTGTGCCAACA
CCGGTGGTAATGTTTAAAGCCAAAGCGATGGATTGTGCTTACTCAGCCTGTATTACCGCCTCGCACAACCCGGCCGACTA
CAACGGCATCAAAGTGTTTATTCGTGGTGGCCGTGATGCAGATGAAGTGATCACTCAGAAGATCGAGCAGCAAATTGCCA
CACTGACTTTACAAGACGTGAAATCGATCGACTTTGATCAAGCCGTCAACGACAAACTGATCGACATCATCAACCCGATG
AACGAGTTCGTCGACAGCATCATCAACTTCATCGATATTGAAGCGATCAAAAAAGCCAATCTGCGAGTGTTGATCGACCC
GATGTTCGGGGTGGCGAAAAACGCGCTGCAAACGGTACTGATCAATGGCCGCTGCGACGTGGACGTGATCAACGATGGCA
AAAACCCTGATTTCGGTGGTTTGATGCCTTCGCCTAGCGCTGCCACCTTGTATCGCTTGAAGCATCTGGTGAAACACGAA
GGTTATGACATCGGTATCGGCACCGATGGCGATGCGGACCGCCTTGGCATCATCGATGAAAAAGGCAACTTTATTCACCC
GAACGAAGTGCTGATCCTGCTTTACTACTACCTGCTGGAGTACAAAGGCTGGAAAGGTTCTGTGGTGCGTAACATCGCAA
CCACACATCTGTTGGATAAGATCGCCGCCGATCATGGTGAGCGGTGCTTTGAAGTGCCTGTGGGCTTTAAACACATCTCT
TCACAAATGGAAGCGGACGACTCTCTGATTGGCGGGGAGAGCTCTGGCGGCCTCACGATTCGTGGTCACATCAAGGGGAA
AGATGGCGTGTTCGCTTCTAGCCTATTGGTGGAAATGATCAGCGTGACGGGCAAGAAACTCTCTGAGCTGTTAACCGAGA
TCTATGATCGTTACGGCTATGCCTACACTGCGGAAGGCGATTGCAAATTTAAGCCCGCTCAGCGTGATGAGATCTACAAC
AAGGTCTACATTGAGAAAAAACTGCCTGAGTTTGAATTCGACATCGATAAAGTCAGCTATGAAGATGGGGCGAAAGTCTA
CTTCAAGAACGGTGGCTGGGTAATTGCCCGATTCTCCGGTACTGAACCTTTATTACGTATTTTCGCCGAAATGGCCGACA
AAGATACTGCGGAGCGTGTTCTTCAACAGATGAAAGCTTTCTTGGCGTTGTAA

Upstream 100 bases:

>100_bases
GTGCCCGTTTGCTAATACCTAAGCGTTTTATATGCCCAGACCACTTGTCGTTGCAACCAAGACTCTTGCAGCGTCAGTAG
AAAAGGGATAGGGGGAGAAA

Downstream 100 bases:

>100_bases
TCATCGCCTTGTCAAATCATCCCCTGAGGTTAAGTCCCCTCAGCGGAGAAGAACACTTGCCCGACGCTCGACGTCGGGCT
TTTTTATGCAGGTAACATAG

Product: putative phosphoglucomutase/phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MIKFGTGGWRAFIGEEFTKDNVRLVAQALANIIHHEQAANEGFVIGYDRRFLSDKAGRWFAEVLAANGVVVSFIDKFVPT
PVVMFKAKAMDCAYSACITASHNPADYNGIKVFIRGGRDADEVITQKIEQQIATLTLQDVKSIDFDQAVNDKLIDIINPM
NEFVDSIINFIDIEAIKKANLRVLIDPMFGVAKNALQTVLINGRCDVDVINDGKNPDFGGLMPSPSAATLYRLKHLVKHE
GYDIGIGTDGDADRLGIIDEKGNFIHPNEVLILLYYYLLEYKGWKGSVVRNIATTHLLDKIAADHGERCFEVPVGFKHIS
SQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMISVTGKKLSELLTEIYDRYGYAYTAEGDCKFKPAQRDEIYN
KVYIEKKLPEFEFDIDKVSYEDGAKVYFKNGGWVIARFSGTEPLLRIFAEMADKDTAERVLQQMKAFLAL

Sequences:

>Translated_470_residues
MIKFGTGGWRAFIGEEFTKDNVRLVAQALANIIHHEQAANEGFVIGYDRRFLSDKAGRWFAEVLAANGVVVSFIDKFVPT
PVVMFKAKAMDCAYSACITASHNPADYNGIKVFIRGGRDADEVITQKIEQQIATLTLQDVKSIDFDQAVNDKLIDIINPM
NEFVDSIINFIDIEAIKKANLRVLIDPMFGVAKNALQTVLINGRCDVDVINDGKNPDFGGLMPSPSAATLYRLKHLVKHE
GYDIGIGTDGDADRLGIIDEKGNFIHPNEVLILLYYYLLEYKGWKGSVVRNIATTHLLDKIAADHGERCFEVPVGFKHIS
SQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMISVTGKKLSELLTEIYDRYGYAYTAEGDCKFKPAQRDEIYN
KVYIEKKLPEFEFDIDKVSYEDGAKVYFKNGGWVIARFSGTEPLLRIFAEMADKDTAERVLQQMKAFLAL
>Mature_470_residues
MIKFGTGGWRAFIGEEFTKDNVRLVAQALANIIHHEQAANEGFVIGYDRRFLSDKAGRWFAEVLAANGVVVSFIDKFVPT
PVVMFKAKAMDCAYSACITASHNPADYNGIKVFIRGGRDADEVITQKIEQQIATLTLQDVKSIDFDQAVNDKLIDIINPM
NEFVDSIINFIDIEAIKKANLRVLIDPMFGVAKNALQTVLINGRCDVDVINDGKNPDFGGLMPSPSAATLYRLKHLVKHE
GYDIGIGTDGDADRLGIIDEKGNFIHPNEVLILLYYYLLEYKGWKGSVVRNIATTHLLDKIAADHGERCFEVPVGFKHIS
SQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMISVTGKKLSELLTEIYDRYGYAYTAEGDCKFKPAQRDEIYN
KVYIEKKLPEFEFDIDKVSYEDGAKVYFKNGGWVIARFSGTEPLLRIFAEMADKDTAERVLQQMKAFLAL

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=499, Percent_Identity=25.4509018036072, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI290463102, Length=483, Percent_Identity=25.4658385093168, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI133922562, Length=514, Percent_Identity=23.7354085603113, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI31377548, Length=534, Percent_Identity=25.4681647940075, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI290463104, Length=322, Percent_Identity=25.776397515528, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1786904, Length=499, Percent_Identity=27.8557114228457, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788361, Length=451, Percent_Identity=25.4988913525499, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1789566, Length=481, Percent_Identity=23.0769230769231, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17535441, Length=502, Percent_Identity=26.4940239043825, Blast_Score=129, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6323752, Length=504, Percent_Identity=26.1904761904762, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322722, Length=537, Percent_Identity=26.0707635009311, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323934, Length=407, Percent_Identity=24.5700245700246, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864244, Length=528, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI20129809, Length=525, Percent_Identity=24.952380952381, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24651977, Length=433, Percent_Identity=25.1732101616628, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24653722, Length=378, Percent_Identity=25.1322751322751, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 52284; Mature: 52284

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKFGTGGWRAFIGEEFTKDNVRLVAQALANIIHHEQAANEGFVIGYDRRFLSDKAGRWF
CCEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHH
AEVLAANGVVVSFIDKFVPTPVVMFKAKAMDCAYSACITASHNPADYNGIKVFIRGGRDA
HHHHHCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCH
DEVITQKIEQQIATLTLQDVKSIDFDQAVNDKLIDIINPMNEFVDSIINFIDIEAIKKAN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LRVLIDPMFGVAKNALQTVLINGRCDVDVINDGKNPDFGGLMPSPSAATLYRLKHLVKHE
CEEEECCHHHHHHHHHHEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GYDIGIGTDGDADRLGIIDEKGNFIHPNEVLILLYYYLLEYKGWKGSVVRNIATTHLLDK
CEEEECCCCCCCCCEEEEECCCCEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IAADHGERCFEVPVGFKHISSQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMI
HHHHCCCCEEECCCCHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCHHHHHHHHHHH
SVTGKKLSELLTEIYDRYGYAYTAEGDCKFKPAQRDEIYNKVYIEKKLPEFEFDIDKVSY
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHEEECCCCCCCCCCCCCCCC
EDGAKVYFKNGGWVIARFSGTEPLLRIFAEMADKDTAERVLQQMKAFLAL
CCCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKFGTGGWRAFIGEEFTKDNVRLVAQALANIIHHEQAANEGFVIGYDRRFLSDKAGRWF
CCEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHH
AEVLAANGVVVSFIDKFVPTPVVMFKAKAMDCAYSACITASHNPADYNGIKVFIRGGRDA
HHHHHCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCH
DEVITQKIEQQIATLTLQDVKSIDFDQAVNDKLIDIINPMNEFVDSIINFIDIEAIKKAN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LRVLIDPMFGVAKNALQTVLINGRCDVDVINDGKNPDFGGLMPSPSAATLYRLKHLVKHE
CEEEECCHHHHHHHHHHEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GYDIGIGTDGDADRLGIIDEKGNFIHPNEVLILLYYYLLEYKGWKGSVVRNIATTHLLDK
CEEEECCCCCCCCCEEEEECCCCEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IAADHGERCFEVPVGFKHISSQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMI
HHHHCCCCEEECCCCHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCHHHHHHHHHHH
SVTGKKLSELLTEIYDRYGYAYTAEGDCKFKPAQRDEIYNKVYIEKKLPEFEFDIDKVSY
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHEEECCCCCCCCCCCCCCCC
EDGAKVYFKNGGWVIARFSGTEPLLRIFAEMADKDTAERVLQQMKAFLAL
CCCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]