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The map label for this gene is gmhA [H]

Identifier: 227080762

GI number: 227080762

Start: 566109

End: 566699

Strand: Reverse

Name: gmhA [H]

Synonym: VCM66_0537

Alternate gene names: 227080762

Gene position: 566699-566109 (Counterclockwise)

Preceding gene: 227080763

Following gene: 227080761

Centisome position: 19.59

GC content: 47.55

Gene sequence:

>591_bases
ATGCTCGATAGCATTAAAGACAGTTTTACCGAAAGCATTCAAATTCAAATCGCCGCAGCGGAGGCGTTACCCGATGCCAT
TATGCATGCCGCACAAGCCATGGTGGCGAGTTTACTTAACGGTCATAAAATTCTCTGCTGCGGTAACGGTGGCTCGTCGG
TCAATGCACAACAATTTGTTTCTTGCCTTCTAAATCGCTTTGAGACCGAACGCCCAAGCTTACCGGGAATGGCTCTGACT
GCAGATAACACGACGCTCACCGCCGTCGCTAACGACTACCACTATCAAGAAATCTTCTCAAAACAGGTTCGAGCTTTTGG
CCAACCCGGTGATATCTTGCTTGCAATATCAACCAGCGGTAACAGTAAAAATATCATCAAAGCAATGGAAGCGGCCGTAA
CTCGCGACATGACGATCATTGCTCTCACAGGCAAAGATGGCGGTGAAATGGCCGGACTGCTTGGTGAAAATGACGTGGAA
ATTCGGATCCCATCACACCGTACCGCTCGCATTCATGAAGTTCATATGGTAACGCTACACTGCCTATGTGATTTGATTGA
TCAAGTGTTATTCCCAGCCCATGAAGAGTAA

Upstream 100 bases:

>100_bases
GAATAGTCACAGTGCGGATTTTCGTTTTGATGTGATTGCCATTCATCAACAAGGGCAACATATTGATTGGTTAAAAAACG
CTATTACTGAAGGATAAACA

Downstream 100 bases:

>100_bases
ATATGAAAAGCATTAGACTTCTTATCGTTTCCGGTTTGCTCGCCACTCTAACAGGGTGTGCCGGACTGTTTATCGCGGGT
GCCGCAACCACAGCCAATAT

Product: putative phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MLDSIKDSFTESIQIQIAAAEALPDAIMHAAQAMVASLLNGHKILCCGNGGSSVNAQQFVSCLLNRFETERPSLPGMALT
ADNTTLTAVANDYHYQEIFSKQVRAFGQPGDILLAISTSGNSKNIIKAMEAAVTRDMTIIALTGKDGGEMAGLLGENDVE
IRIPSHRTARIHEVHMVTLHCLCDLIDQVLFPAHEE

Sequences:

>Translated_196_residues
MLDSIKDSFTESIQIQIAAAEALPDAIMHAAQAMVASLLNGHKILCCGNGGSSVNAQQFVSCLLNRFETERPSLPGMALT
ADNTTLTAVANDYHYQEIFSKQVRAFGQPGDILLAISTSGNSKNIIKAMEAAVTRDMTIIALTGKDGGEMAGLLGENDVE
IRIPSHRTARIHEVHMVTLHCLCDLIDQVLFPAHEE
>Mature_196_residues
MLDSIKDSFTESIQIQIAAAEALPDAIMHAAQAMVASLLNGHKILCCGNGGSSVNAQQFVSCLLNRFETERPSLPGMALT
ADNTTLTAVANDYHYQEIFSKQVRAFGQPGDILLAISTSGNSKNIIKAMEAAVTRDMTIIALTGKDGGEMAGLLGENDVE
IRIPSHRTARIHEVHMVTLHCLCDLIDQVLFPAHEE

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=196, Percent_Identity=68.3673469387755, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1786416, Length=164, Percent_Identity=45.7317073170732, Blast_Score=144, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21117; Mature: 21117

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSIKDSFTESIQIQIAAAEALPDAIMHAAQAMVASLLNGHKILCCGNGGSSVNAQQFV
CCCCHHHHHCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHH
SCLLNRFETERPSLPGMALTADNTTLTAVANDYHYQEIFSKQVRAFGQPGDILLAISTSG
HHHHHHHCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEECCC
NSKNIIKAMEAAVTRDMTIIALTGKDGGEMAGLLGENDVEIRIPSHRTARIHEVHMVTLH
CCHHHHHHHHHHHHCCEEEEEEECCCCCCEECCCCCCCEEEEECCCCCCCHHHHHHHHHH
CLCDLIDQVLFPAHEE
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLDSIKDSFTESIQIQIAAAEALPDAIMHAAQAMVASLLNGHKILCCGNGGSSVNAQQFV
CCCCHHHHHCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHH
SCLLNRFETERPSLPGMALTADNTTLTAVANDYHYQEIFSKQVRAFGQPGDILLAISTSG
HHHHHHHCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEECCC
NSKNIIKAMEAAVTRDMTIIALTGKDGGEMAGLLGENDVEIRIPSHRTARIHEVHMVTLH
CCHHHHHHHHHHHHCCEEEEEEECCCCCCEECCCCCCCEEEEECCCCCCCHHHHHHHHHH
CLCDLIDQVLFPAHEE
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA