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The map label for this gene is yggV [C]

Identifier: 227080666

GI number: 227080666

Start: 472408

End: 473010

Strand: Reverse

Name: yggV [C]

Synonym: VCM66_0441

Alternate gene names: 227080666

Gene position: 473010-472408 (Counterclockwise)

Preceding gene: 227080667

Following gene: 227080665

Centisome position: 16.35

GC content: 52.24

Gene sequence:

>603_bases
ATGAAAAAGATCGTTTTAGCCACGGGCAATCAAGGCAAAGTGCGTGAAATGGCGGACCTATTATCCGATTTTGGGTTTGA
TGTCGTCGCGCAAAGCGAATTCAACGTCCCTGAAGCGGCAGAAACAGGCACCACTTTTATTGAAAATGCGATCATCAAGG
CACGTCATGCCGCGCAAATTACCGGCTTACCGGCGATTGCCGATGATTCCGGTTTGGAAGTGGATTACCTAAACGGCGCG
CCGGGCATCTATTCTGCGCGCTACGCGGGCGAGCATGCCAGCGACGGCGACAATCTCAATAAGCTGCTAGTGGCGATGCA
AGATGTGCCAGACGACCAGCGCAGCGCGCGTTTTCATTGTGTACTGGTGTTGATGCGCCACGCCGATGATCCAACGCCTA
TCGTTTGCCACGGCAAATGGGAAGGCAAAATCCTCACCTCACCACACGGCAGTAATGGCTTTGGTTACGATCCGATTTTC
TGGGTTCCGGAAGAAAACTGCGCTTCTGCTGAGCTAGAACCGGTGCGCAAAAAGCAGCTATCCCATCGCGGTAAAGCTCT
GCAAAAACTGTTCAAAGCGATTGAAGAGCAGCGTACATGCTAA

Upstream 100 bases:

>100_bases
CTTCAGCCAAAAGTTCTATACCGAACAGTAATTTTATAGAAGACATGGGGAATCTACGACGCAGCCGTCGGGTTTCCCCA
TATAAACCACAGAGAACAGC

Downstream 100 bases:

>100_bases
CGCCTCCACCGCTTAGCCTATACATTCATATTCCGTGGTGCGTGCAGAAATGCCCGTACTGCGATTTCAACTCGCACGCG
CAGAAAGGCGAGATTCCTGA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKKIVLATGNQGKVREMADLLSDFGFDVVAQSEFNVPEAAETGTTFIENAIIKARHAAQITGLPAIADDSGLEVDYLNGA
PGIYSARYAGEHASDGDNLNKLLVAMQDVPDDQRSARFHCVLVLMRHADDPTPIVCHGKWEGKILTSPHGSNGFGYDPIF
WVPEENCASAELEPVRKKQLSHRGKALQKLFKAIEEQRTC

Sequences:

>Translated_200_residues
MKKIVLATGNQGKVREMADLLSDFGFDVVAQSEFNVPEAAETGTTFIENAIIKARHAAQITGLPAIADDSGLEVDYLNGA
PGIYSARYAGEHASDGDNLNKLLVAMQDVPDDQRSARFHCVLVLMRHADDPTPIVCHGKWEGKILTSPHGSNGFGYDPIF
WVPEENCASAELEPVRKKQLSHRGKALQKLFKAIEEQRTC
>Mature_200_residues
MKKIVLATGNQGKVREMADLLSDFGFDVVAQSEFNVPEAAETGTTFIENAIIKARHAAQITGLPAIADDSGLEVDYLNGA
PGIYSARYAGEHASDGDNLNKLLVAMQDVPDDQRSARFHCVLVLMRHADDPTPIVCHGKWEGKILTSPHGSNGFGYDPIF
WVPEENCASAELEPVRKKQLSHRGKALQKLFKAIEEQRTC

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=191, Percent_Identity=30.8900523560209, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789324, Length=194, Percent_Identity=67.0103092783505, Blast_Score=276, Evalue=6e-76,
Organism=Drosophila melanogaster, GI19920712, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21890; Mature: 21890

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVLATGNQGKVREMADLLSDFGFDVVAQSEFNVPEAAETGTTFIENAIIKARHAAQI
CCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCCCCCHHCCHHHHHHHHHHHHHHHHH
TGLPAIADDSGLEVDYLNGAPGIYSARYAGEHASDGDNLNKLLVAMQDVPDDQRSARFHC
CCCCCCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
VLVLMRHADDPTPIVCHGKWEGKILTSPHGSNGFGYDPIFWVPEENCASAELEPVRKKQL
HHHHHHHCCCCCCEEEECCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHH
SHRGKALQKLFKAIEEQRTC
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIVLATGNQGKVREMADLLSDFGFDVVAQSEFNVPEAAETGTTFIENAIIKARHAAQI
CCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCCCCCHHCCHHHHHHHHHHHHHHHHH
TGLPAIADDSGLEVDYLNGAPGIYSARYAGEHASDGDNLNKLLVAMQDVPDDQRSARFHC
CCCCCCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
VLVLMRHADDPTPIVCHGKWEGKILTSPHGSNGFGYDPIFWVPEENCASAELEPVRKKQL
HHHHHHHCCCCCCEEEECCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHH
SHRGKALQKLFKAIEEQRTC
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]