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The map label for this gene is yggW [H]

Identifier: 227080665

GI number: 227080665

Start: 471239

End: 472414

Strand: Reverse

Name: yggW [H]

Synonym: VCM66_0440

Alternate gene names: 227080665

Gene position: 472414-471239 (Counterclockwise)

Preceding gene: 227080666

Following gene: 227080662

Centisome position: 16.33

GC content: 52.21

Gene sequence:

>1176_bases
ATGCTAACGCCTCCACCGCTTAGCCTATACATTCATATTCCGTGGTGCGTGCAGAAATGCCCGTACTGCGATTTCAACTC
GCACGCGCAGAAAGGCGAGATTCCTGAGCAAGAGTATTTGGATGCGCTGCTGGAAGATCTGGATCGCGACATCGAACGTT
ACCAGCTCAAGGGCGATCCGCGCCTGCTGCACTCGATCTTTATTGGCGGTGGCACACCGAGCCTTATCTCAGCAGAAGGG
ATCGCGCGCTTGCTGCAAGGCGTTGCCGAGCGTATTGCGTTTAAGCCAGAGATTGAAATCACCATGGAAGCCAACCCCGG
CACGATTGAAGCGCAGCGTTTTGCTGGCTATCGCACCGCTGGGGTTACACGTATTTCGATTGGTGTGCAGAGTTTTGAGC
CAGAAAAATTAGCGCGTTTAGGGCGCATTCACGGTCAACAAGAAGCGGTTCGCGCCGCTAAGCTCGCCCACCAAATTGGC
CTCAACAGCTTTAATTTGGATTTGATGCACGGCTTACCAGATCAAACGCCAGAGCAAGCACTGGCTGATTTGGATCAGGC
GATCGCGCTCAATCCGCCGCATCTCTCTTGGTATCAACTGACGATTGAACCCAACACGCTGTTTTACTCGAAACCGCCTA
AGCTGCCAGATGAAGATGCGCTATGGGATATTTTCGAGCTCGGCCATCAAAAGCTCAGTGATGCAGGGTATGTGCAGTAC
GAGATTTCTGGCTATAGCAAGCCGGGCTATCAGTGTCAGCACAACCTCAACTATTGGCGCTTTGGGGACTACCTCGGGAT
TGGCTGCGGCGCGCACGGCAAACTGAGTTTTGCTGATGGGCGCATTGTCCGTACCACCAAAACCAAGCACCCGCGCGGCT
ACTTGGCAGCGTTGAACAATCTCGCCAAAGCTTATTTGGATAGCGAGCAGTTGGTTGCCGATCAAGACAAGCCGTTTGAG
TTTTTTATGAATCGCTTTCGCTTGATTGAGCCCTGCCCGAAAGCCGATTTTACCGCCACCACGGGACTTACGATTGACGT
GATCCGCCCAACCTTAGATTGGGCGCTCAGTGAAGGTTATCTCAGTGAAGATGATCAGCACTGGCAAATCACGGAAAAGG
GCAAACTGTTCCTCAATGATCTGCTCGAAGCCTTTATGGCTGATGAAGAAGAATAA

Upstream 100 bases:

>100_bases
ACTGCGCTTCTGCTGAGCTAGAACCGGTGCGCAAAAAGCAGCTATCCCATCGCGGTAAAGCTCTGCAAAAACTGTTCAAA
GCGATTGAAGAGCAGCGTAC

Downstream 100 bases:

>100_bases
CCAAGAGGCGCGTGCGCCTCTTTATTTTTATCTTTTATACCCAAACGACTTGCAGTTGCAGGTAGGCGGCAAACGAGTGA
CAAATTTGTCTGGAACAAAT

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MLTPPPLSLYIHIPWCVQKCPYCDFNSHAQKGEIPEQEYLDALLEDLDRDIERYQLKGDPRLLHSIFIGGGTPSLISAEG
IARLLQGVAERIAFKPEIEITMEANPGTIEAQRFAGYRTAGVTRISIGVQSFEPEKLARLGRIHGQQEAVRAAKLAHQIG
LNSFNLDLMHGLPDQTPEQALADLDQAIALNPPHLSWYQLTIEPNTLFYSKPPKLPDEDALWDIFELGHQKLSDAGYVQY
EISGYSKPGYQCQHNLNYWRFGDYLGIGCGAHGKLSFADGRIVRTTKTKHPRGYLAALNNLAKAYLDSEQLVADQDKPFE
FFMNRFRLIEPCPKADFTATTGLTIDVIRPTLDWALSEGYLSEDDQHWQITEKGKLFLNDLLEAFMADEEE

Sequences:

>Translated_391_residues
MLTPPPLSLYIHIPWCVQKCPYCDFNSHAQKGEIPEQEYLDALLEDLDRDIERYQLKGDPRLLHSIFIGGGTPSLISAEG
IARLLQGVAERIAFKPEIEITMEANPGTIEAQRFAGYRTAGVTRISIGVQSFEPEKLARLGRIHGQQEAVRAAKLAHQIG
LNSFNLDLMHGLPDQTPEQALADLDQAIALNPPHLSWYQLTIEPNTLFYSKPPKLPDEDALWDIFELGHQKLSDAGYVQY
EISGYSKPGYQCQHNLNYWRFGDYLGIGCGAHGKLSFADGRIVRTTKTKHPRGYLAALNNLAKAYLDSEQLVADQDKPFE
FFMNRFRLIEPCPKADFTATTGLTIDVIRPTLDWALSEGYLSEDDQHWQITEKGKLFLNDLLEAFMADEEE
>Mature_391_residues
MLTPPPLSLYIHIPWCVQKCPYCDFNSHAQKGEIPEQEYLDALLEDLDRDIERYQLKGDPRLLHSIFIGGGTPSLISAEG
IARLLQGVAERIAFKPEIEITMEANPGTIEAQRFAGYRTAGVTRISIGVQSFEPEKLARLGRIHGQQEAVRAAKLAHQIG
LNSFNLDLMHGLPDQTPEQALADLDQAIALNPPHLSWYQLTIEPNTLFYSKPPKLPDEDALWDIFELGHQKLSDAGYVQY
EISGYSKPGYQCQHNLNYWRFGDYLGIGCGAHGKLSFADGRIVRTTKTKHPRGYLAALNNLAKAYLDSEQLVADQDKPFE
FFMNRFRLIEPCPKADFTATTGLTIDVIRPTLDWALSEGYLSEDDQHWQITEKGKLFLNDLLEAFMADEEE

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=272, Percent_Identity=34.5588235294118, Blast_Score=172, Evalue=3e-43,
Organism=Escherichia coli, GI1789325, Length=388, Percent_Identity=67.5257731958763, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI87082341, Length=247, Percent_Identity=31.5789473684211, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44093; Mature: 44093

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPPPLSLYIHIPWCVQKCPYCDFNSHAQKGEIPEQEYLDALLEDLDRDIERYQLKGDP
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
RLLHSIFIGGGTPSLISAEGIARLLQGVAERIAFKPEIEITMEANPGTIEAQRFAGYRTA
HEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHHHCCEECC
GVTRISIGVQSFEPEKLARLGRIHGQQEAVRAAKLAHQIGLNSFNLDLMHGLPDQTPEQA
CEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHH
LADLDQAIALNPPHLSWYQLTIEPNTLFYSKPPKLPDEDALWDIFELGHQKLSDAGYVQY
HHHHHHHHCCCCCCCEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
EISGYSKPGYQCQHNLNYWRFGDYLGIGCGAHGKLSFADGRIVRTTKTKHPRGYLAALNN
EECCCCCCCCCEECCCCEEEECCEEEECCCCCCEEEECCCEEEEEECCCCCCHHHHHHHH
LAKAYLDSEQLVADQDKPFEFFMNRFRLIEPCPKADFTATTGLTIDVIRPTLDWALSEGY
HHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCEEEEECHHHHHHHCCCC
LSEDDQHWQITEKGKLFLNDLLEAFMADEEE
CCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLTPPPLSLYIHIPWCVQKCPYCDFNSHAQKGEIPEQEYLDALLEDLDRDIERYQLKGDP
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
RLLHSIFIGGGTPSLISAEGIARLLQGVAERIAFKPEIEITMEANPGTIEAQRFAGYRTA
HEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHHHCCEECC
GVTRISIGVQSFEPEKLARLGRIHGQQEAVRAAKLAHQIGLNSFNLDLMHGLPDQTPEQA
CEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHH
LADLDQAIALNPPHLSWYQLTIEPNTLFYSKPPKLPDEDALWDIFELGHQKLSDAGYVQY
HHHHHHHHCCCCCCCEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
EISGYSKPGYQCQHNLNYWRFGDYLGIGCGAHGKLSFADGRIVRTTKTKHPRGYLAALNN
EECCCCCCCCCEECCCCEEEECCEEEECCCCCCEEEECCCEEEEEECCCCCCHHHHHHHH
LAKAYLDSEQLVADQDKPFEFFMNRFRLIEPCPKADFTATTGLTIDVIRPTLDWALSEGY
HHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCEEEEECHHHHHHHCCCC
LSEDDQHWQITEKGKLFLNDLLEAFMADEEE
CCCCCCCEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]