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The map label for this gene is csgD [H]

Identifier: 227080607

GI number: 227080607

Start: 406405

End: 407049

Strand: Reverse

Name: csgD [H]

Synonym: VCM66_0381

Alternate gene names: 227080607

Gene position: 407049-406405 (Counterclockwise)

Preceding gene: 227080634

Following gene: 227080606

Centisome position: 14.07

GC content: 43.72

Gene sequence:

>645_bases
ATGCAACGAGCCAACTATGCACGCACGATTTATTTATTAACGACACAGCCAAAAGCGTTACATCCCAGTATTCAAGCCGC
CATTGAGCAGTTGAATCTGCCCGTCCCGGTGATTGAACCAGAACGCTTATTGCGCGAGTATCAATCCGATAAACACAAAA
TATTGTTGCTCGACCATGCGGAAAATGGCCTGATTCGCCAGCAATTGGGTCCCCTAAAGCTTACCAGCCCGTACTTCGAA
ACCATCTTGTTTAATGTCGAGAAACGGTTAAGAACAGAAGATCTGCTCACTTTTGGCAACCTCAAAGGTCTGTTTTATGC
CAATGAAGACACAGGCTTTATTGCCCACGGTCTTGGGGAGATCATTAATGGCCAAAACTGGCTACCTCGCCATGTCAGCA
GTCAGTTGCTGCATTACTATCGTTACGCTTTCCAAAGCCATCAAGTTCAAGCCACGGTCGATTTGACTGCACGTGAAATT
CAGATCCTGCGCTGTTTACAAACTGGCGCATCGAATATGCAAATCGCTGAGAATTTATTTATTAGTGAGTTCACGGTGAA
ATCGCATCTTTATCAGATATTTAAAAAGCTAAACGTGAAAAATCGAGTCAAAGCGATCGCTTGGGTTAATCAAAATTTAC
TGTAA

Upstream 100 bases:

>100_bases
ATTGAGGTGCTCCGCAAACTGCTTTTATCGCATAGCGCCAAAATCTATTTTTCGCCATATTAAGTGCATTATTTCATATT
AACTGAGTCTGTAATTCATC

Downstream 100 bases:

>100_bases
AGGCGCTCAACCTAGCGGAGTGAATTCACCATGAGTGAGTGGAGAAAAATGTAGTAACAATGCGACTTCACACACATTTT
TTCGGCCAAGAGCCTCAACG

Product: transcriptional regulator, LuxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MQRANYARTIYLLTTQPKALHPSIQAAIEQLNLPVPVIEPERLLREYQSDKHKILLLDHAENGLIRQQLGPLKLTSPYFE
TILFNVEKRLRTEDLLTFGNLKGLFYANEDTGFIAHGLGEIINGQNWLPRHVSSQLLHYYRYAFQSHQVQATVDLTAREI
QILRCLQTGASNMQIAENLFISEFTVKSHLYQIFKKLNVKNRVKAIAWVNQNLL

Sequences:

>Translated_214_residues
MQRANYARTIYLLTTQPKALHPSIQAAIEQLNLPVPVIEPERLLREYQSDKHKILLLDHAENGLIRQQLGPLKLTSPYFE
TILFNVEKRLRTEDLLTFGNLKGLFYANEDTGFIAHGLGEIINGQNWLPRHVSSQLLHYYRYAFQSHQVQATVDLTAREI
QILRCLQTGASNMQIAENLFISEFTVKSHLYQIFKKLNVKNRVKAIAWVNQNLL
>Mature_214_residues
MQRANYARTIYLLTTQPKALHPSIQAAIEQLNLPVPVIEPERLLREYQSDKHKILLLDHAENGLIRQQLGPLKLTSPYFE
TILFNVEKRLRTEDLLTFGNLKGLFYANEDTGFIAHGLGEIINGQNWLPRHVSSQLLHYYRYAFQSHQVQATVDLTAREI
QILRCLQTGASNMQIAENLFISEFTVKSHLYQIFKKLNVKNRVKAIAWVNQNLL

Specific function: The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA t

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787277, Length=163, Percent_Identity=36.8098159509202, Blast_Score=97, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 24737; Mature: 24737

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRANYARTIYLLTTQPKALHPSIQAAIEQLNLPVPVIEPERLLREYQSDKHKILLLDHA
CCCCCCEEEEEEEECCCCHHCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECC
ENGLIRQQLGPLKLTSPYFETILFNVEKRLRTEDLLTFGNLKGLFYANEDTGFIAHGLGE
CCCHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
IINGQNWLPRHVSSQLLHYYRYAFQSHQVQATVDLTAREIQILRCLQTGASNMQIAENLF
HHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHH
ISEFTVKSHLYQIFKKLNVKNRVKAIAWVNQNLL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQRANYARTIYLLTTQPKALHPSIQAAIEQLNLPVPVIEPERLLREYQSDKHKILLLDHA
CCCCCCEEEEEEEECCCCHHCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECC
ENGLIRQQLGPLKLTSPYFETILFNVEKRLRTEDLLTFGNLKGLFYANEDTGFIAHGLGE
CCCHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
IINGQNWLPRHVSSQLLHYYRYAFQSHQVQATVDLTAREIQILRCLQTGASNMQIAENLF
HHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHH
ISEFTVKSHLYQIFKKLNVKNRVKAIAWVNQNLL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8817489; 8905232; 9278503 [H]