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The map label for this gene is sdcS [H]

Identifier: 227080550

GI number: 227080550

Start: 342124

End: 343560

Strand: Reverse

Name: sdcS [H]

Synonym: VCM66_0322

Alternate gene names: 227080550

Gene position: 343560-342124 (Counterclockwise)

Preceding gene: 227080551

Following gene: 227080549

Centisome position: 11.88

GC content: 50.24

Gene sequence:

>1437_bases
TTGAGCCAAGAGGGAAAGCCCATGCCGCAACTGGAACGAGGTCTACTCGTCAAACTCCTGATCTGTTTCTTACTGCCGTT
GGGCGTACTATTGATGCCGATTGATGCAATCCCGATTCAAGATCTCACCTTGGTTCAACACCGTTTACTGGCCATTTTCC
TTCTTGCTGCACTGCTGTGGGTGTTGGAGCCTGTTCCTGTGTTTGCCACGTCGATCCTGATCATTGCCCTTGAACTCGTC
ATGATTTCCGATAAAGGCTTGCATGGCTTTCGAGTGCCCGATCCGCATCATCCGCTCGGTGAACTCCTTAAATACACCGA
TATTTTCAGTGCCTTCTCCTCTCCCATTATCATTTTGTTTATGGGCGGTTTTGCTTTAGCCATCGCCGCATCTAAATACG
AATTGGATAACAACTTAGCACGAGTGCTACTCAAACCTTTTGGCCACCAGCCTAAGTACATCATGCTCGGGTTAATGCTG
ATCACCTCAGTTTTCTCGATGTTTATGTCCAACACAGCGACCACAGTGATGATGTTGGCGCTGCTTGGCCCTATTGTTGC
GTCTGCCCCCAAAGGGGATTTAGGCATCAAAGCTCTGGTGCTATGCATTCCGATTGCGGCCAACACAGGGGGCATCGCAA
CCCCGATCGGCACGCCACCTAACGCTATCGCACTGCAGTATCTAACGGGCGAAAACAGCATTGATTTTCTGTCATGGATG
ATGATGGGATTGCCGTTCGTACTGGTACAACTGACCATCGCTTGGTTCTTACTGCAAAAGCTTTTCCCCTCCTCACAAGC
CACAATGACCTTGAAACTCAAAGGCGAATTTCAACGCGGCTGGCGTGCCATGCTGGTCTACATCACGTTTGCTTTAACCA
TAGTGCTGTGGATGACCACCTCATGGCATGGTATGAACACTTATGTGGTGGCGATTATTCCACTGGCCGTGTTCACCCTC
ACTGGCATCATGGGCAAAGAAGAGCTGAAACAGATCAACTGGGATGTGCTGTGGTTAGTTGCCGGTGGGATCGCGATTGG
TATCGGCCTTGAACAGACGGGACTCGCCCAAGCGTTAGCGCACTCCATCGACTATCAATCTCTCTCACCTATGCTGATTG
TGATTGCTCTTTCGTTGGTGTGCTGGCTAATGGCCAACTTTATGTCTAACACGGCGACTGCCAACTTGATCATGCCGATT
GCCGCTGCGATTGGTACTTCGATGAGTAGCCTTGAGCAAGTCGGCGGCTTACAAGCGCTGTTAGTCGTGGTCGCTTTTTC
CGCGTCACTGGGGATGATTTTGCCCGTTTCGACACCGCCCAACTCGCTTGCTTACTCAACGGGGCTTATCGAAAGCAAAG
ATATGGCAAAAACGGGTTTAGTCATTGGGGGGATTGGGCTTGGCATCGTTTATCTGATGGTGTTCCTACTCGGATAA

Upstream 100 bases:

>100_bases
GAAGCTCGCCACACATCTGCACTGTCACTGATAGCAAAACCCAAAAATTTAACCGCCCTCTAAGACCCATAGATTTCAGT
CGCTTACTCTAAGCTTTCAC

Downstream 100 bases:

>100_bases
ACTCCCTCTTCCTCCCCTCTTTCACAGCTTGTCATCACTCTCGAGATAGCAAGCTGTGAACCTTCTAATCGCACTGAAAT
TGCTTTTGTTTTCCTGATTG

Product: putative transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MSQEGKPMPQLERGLLVKLLICFLLPLGVLLMPIDAIPIQDLTLVQHRLLAIFLLAALLWVLEPVPVFATSILIIALELV
MISDKGLHGFRVPDPHHPLGELLKYTDIFSAFSSPIIILFMGGFALAIAASKYELDNNLARVLLKPFGHQPKYIMLGLML
ITSVFSMFMSNTATTVMMLALLGPIVASAPKGDLGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWM
MMGLPFVLVQLTIAWFLLQKLFPSSQATMTLKLKGEFQRGWRAMLVYITFALTIVLWMTTSWHGMNTYVVAIIPLAVFTL
TGIMGKEELKQINWDVLWLVAGGIAIGIGLEQTGLAQALAHSIDYQSLSPMLIVIALSLVCWLMANFMSNTATANLIMPI
AAAIGTSMSSLEQVGGLQALLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKTGLVIGGIGLGIVYLMVFLLG

Sequences:

>Translated_478_residues
MSQEGKPMPQLERGLLVKLLICFLLPLGVLLMPIDAIPIQDLTLVQHRLLAIFLLAALLWVLEPVPVFATSILIIALELV
MISDKGLHGFRVPDPHHPLGELLKYTDIFSAFSSPIIILFMGGFALAIAASKYELDNNLARVLLKPFGHQPKYIMLGLML
ITSVFSMFMSNTATTVMMLALLGPIVASAPKGDLGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWM
MMGLPFVLVQLTIAWFLLQKLFPSSQATMTLKLKGEFQRGWRAMLVYITFALTIVLWMTTSWHGMNTYVVAIIPLAVFTL
TGIMGKEELKQINWDVLWLVAGGIAIGIGLEQTGLAQALAHSIDYQSLSPMLIVIALSLVCWLMANFMSNTATANLIMPI
AAAIGTSMSSLEQVGGLQALLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKTGLVIGGIGLGIVYLMVFLLG
>Mature_477_residues
SQEGKPMPQLERGLLVKLLICFLLPLGVLLMPIDAIPIQDLTLVQHRLLAIFLLAALLWVLEPVPVFATSILIIALELVM
ISDKGLHGFRVPDPHHPLGELLKYTDIFSAFSSPIIILFMGGFALAIAASKYELDNNLARVLLKPFGHQPKYIMLGLMLI
TSVFSMFMSNTATTVMMLALLGPIVASAPKGDLGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMM
MGLPFVLVQLTIAWFLLQKLFPSSQATMTLKLKGEFQRGWRAMLVYITFALTIVLWMTTSWHGMNTYVVAIIPLAVFTLT
GIMGKEELKQINWDVLWLVAGGIAIGIGLEQTGLAQALAHSIDYQSLSPMLIVIALSLVCWLMANFMSNTATANLIMPIA
AAIGTSMSSLEQVGGLQALLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKTGLVIGGIGLGIVYLMVFLLG

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=538, Percent_Identity=25.4646840148699, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI219802232, Length=462, Percent_Identity=24.025974025974, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI31795546, Length=345, Percent_Identity=24.6376811594203, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI301069349, Length=302, Percent_Identity=26.158940397351, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI19923838, Length=341, Percent_Identity=24.9266862170088, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI31377715, Length=143, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI301069346, Length=143, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI58761541, Length=143, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI301069353, Length=143, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI225637549, Length=148, Percent_Identity=31.7567567567568, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI4506979, Length=148, Percent_Identity=31.7567567567568, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI225637552, Length=148, Percent_Identity=31.7567567567568, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786829, Length=487, Percent_Identity=23.8193018480493, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32565804, Length=409, Percent_Identity=28.361858190709, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71988385, Length=430, Percent_Identity=27.6744186046512, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71989118, Length=459, Percent_Identity=25.4901960784314, Blast_Score=130, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324340, Length=448, Percent_Identity=31.4732142857143, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6322263, Length=415, Percent_Identity=27.4698795180723, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319885, Length=412, Percent_Identity=27.9126213592233, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281362116, Length=520, Percent_Identity=22.1153846153846, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281362114, Length=519, Percent_Identity=22.1579961464355, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281362112, Length=519, Percent_Identity=22.1579961464355, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 51450; Mature: 51319

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEGKPMPQLERGLLVKLLICFLLPLGVLLMPIDAIPIQDLTLVQHRLLAIFLLAALLW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VLEPVPVFATSILIIALELVMISDKGLHGFRVPDPHHPLGELLKYTDIFSAFSSPIIILF
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
MGGFALAIAASKYELDNNLARVLLKPFGHQPKYIMLGLMLITSVFSMFMSNTATTVMMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LLGPIVASAPKGDLGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWM
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHH
MMGLPFVLVQLTIAWFLLQKLFPSSQATMTLKLKGEFQRGWRAMLVYITFALTIVLWMTT
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
SWHGMNTYVVAIIPLAVFTLTGIMGKEELKQINWDVLWLVAGGIAIGIGLEQTGLAQALA
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHEEEECCCCCEECCCCHHHHHHHHH
HSIDYQSLSPMLIVIALSLVCWLMANFMSNTATANLIMPIAAAIGTSMSSLEQVGGLQAL
HHCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCHHHH
LVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKTGLVIGGIGLGIVYLMVFLLG
HHHHHHHCCCCEEEECCCCCCCHHHHCCCCCCCCHHHHCCEEECHHHHHHHHHHHHHC
>Mature Secondary Structure 
SQEGKPMPQLERGLLVKLLICFLLPLGVLLMPIDAIPIQDLTLVQHRLLAIFLLAALLW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VLEPVPVFATSILIIALELVMISDKGLHGFRVPDPHHPLGELLKYTDIFSAFSSPIIILF
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
MGGFALAIAASKYELDNNLARVLLKPFGHQPKYIMLGLMLITSVFSMFMSNTATTVMMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LLGPIVASAPKGDLGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWM
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHH
MMGLPFVLVQLTIAWFLLQKLFPSSQATMTLKLKGEFQRGWRAMLVYITFALTIVLWMTT
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
SWHGMNTYVVAIIPLAVFTLTGIMGKEELKQINWDVLWLVAGGIAIGIGLEQTGLAQALA
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHEEEECCCCCEECCCCHHHHHHHHH
HSIDYQSLSPMLIVIALSLVCWLMANFMSNTATANLIMPIAAAIGTSMSSLEQVGGLQAL
HHCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCHHHH
LVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKTGLVIGGIGLGIVYLMVFLLG
HHHHHHHCCCCEEEECCCCCCCHHHHCCCCCCCCHHHHCCEEECHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA