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The map label for this gene is cadC [H]

Identifier: 227080492

GI number: 227080492

Start: 268054

End: 269679

Strand: Direct

Name: cadC [H]

Synonym: VCM66_0263

Alternate gene names: 227080492

Gene position: 268054-269679 (Clockwise)

Preceding gene: 227080491

Following gene: 227080493

Centisome position: 9.27

GC content: 50.12

Gene sequence:

>1626_bases
GTGTGTGGTGCTCGAGCATATTCTGCCTCTTACCGATGCTATCTTCCTGATACAAAGAGCTATTCTATGATTGGAATCTG
TTTTCAAATCAATGACTGGGTTCTGTGCATTGATGAGAATAAGCTGTATCGCCAAGATAGGGAGGTCTCGGCCGAGCCGC
GTCTTATTAACTTGCTGCATTTTCTTGCGGAGCATGCCGGAGAGGTATTCGGCCGTGAGGAACTCATTCAACATGTCTGG
GACGGGGCGATTGTCACCGACCAAGTGGTCACTCAATCCATTTTTGAGTTGCGTAAGCTATTGCGCGATGGACGCGAAGA
AAACCTCAGCTATGTGGTGACGGTGCCTAAGCGTGGCTATAAGTTAGTCGCGAATGTGCAGCGTCTCGATGGCAATCCCT
ATGTTTCTCGCCAAGAAGAGTCGACAGCCAGTGATGTCTGTTTGGCGGACGATATCGACGACGTGGAAGACGCCGTTCCC
GAGATTGTATTTCCTGCCGGCCCGTTAACGCGCGCCGTGTGCCAAAGTCAGCAACCGAAGAAATCAAGCAAGCCGAATGT
GAGCCGTTGGCGCTTAAACCTGCTCAATGCGATCTGGATTGGCTTAGTGATTGTAGCGATGGGCTTTTTTACTGTGCAGC
AGTCGCAAGTGCGCATCACCCAAGTGGTGGATACCCATCTGATTGAATTTAAATTCCAAGACGGTTTTCATGCTCAGGCG
CTCACGCATGAGCTTGCCGATGGTATCGCACAAAAGCTGATGGCCGATCTGACCCAAGTGAGTGATTATCGGGTCATTCT
CGGTAAAACGGCTTACAGCTCAGGCATTTTGCCCGGTAAGTCGATCATGGTGCGAGTCAATGACCAAGATGGCCATGAGT
TTTTAGATCTTGAGCTTAAGAACAACTCTTCCGATGCGGTGCTGTTTAGTCGCCAATATCCGCTCGATAGCCAGCATCTG
GCCTCTGTGCTGAAAAGTGCCGAGTGGGATGTGATGCAAGCGTTGAAAATCCCGAATGCAGAGCAGCAAGCACAGCGTTT
ATTGGTGGATTTTCCGCGTCAACCCGCGGCGTTAGGGCTGTATGTGCGCGCCAATCATTACTTGAATGTTGCCGATCGTC
CGCAGTTCCAAAAAGGCATTTACTTATTGGAGCAAGTGCTGAAATTAGAGCCGGATAACCATTATGTCCAAGCCGAATTA
CTGATTGCGTACCATGTGCAGCAAGCGATCAGCCCAGATCAGGCGCTCAATCAAGATCGGATGCTGGTGTTGAGTGAGCA
GTTGCAGCAGGTGAGTTACTCCCCTCAAGCGGTGGTGCAGCCACGCATTTATGAAGCGTTAGCACTGCAAGCAACAGTCG
AAAACCAAGTGGAAACCGCCACGCACTATTTGGCGCAAGCTCAGGGTTTGCGGGAATCGGTGCTTTCATATGTGCTGCAA
GGCAAGCATGCTGAACTCAAAGGCGATCTGGATGGCGCAAGCGATGCCTACAGTGAAGCGTTTTATATGGACACATCGCT
GGAAACTTATCTGCTGTGCGAAAACTTGGTGTTCCACTCTAACTTAAAATCCATTGATTACGCCATGTACCGCTCGGTGC
ATCCTTCGGTGGTTCGTTTACTGTAA

Upstream 100 bases:

>100_bases
ATGACGTTGTCTGATGGTTAAACAACCTAAGTTTGCAATTTTTAGCCTTATCAATAGTAGGTGAAATAGATTGGTGCACT
TATAATTTCGCTCTTCATCG

Downstream 100 bases:

>100_bases
CGCTCGTCTACGGTCAATTTCATCTCTCTATCCCCAAATGACTTGGAATGACTGGTAAGAAGGGGATAGAGCGGACTTGT
GCCTTCTTTCTCCGAACTGG

Product: DNA-binding transcriptional activator CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MCGARAYSASYRCYLPDTKSYSMIGICFQINDWVLCIDENKLYRQDREVSAEPRLINLLHFLAEHAGEVFGREELIQHVW
DGAIVTDQVVTQSIFELRKLLRDGREENLSYVVTVPKRGYKLVANVQRLDGNPYVSRQEESTASDVCLADDIDDVEDAVP
EIVFPAGPLTRAVCQSQQPKKSSKPNVSRWRLNLLNAIWIGLVIVAMGFFTVQQSQVRITQVVDTHLIEFKFQDGFHAQA
LTHELADGIAQKLMADLTQVSDYRVILGKTAYSSGILPGKSIMVRVNDQDGHEFLDLELKNNSSDAVLFSRQYPLDSQHL
ASVLKSAEWDVMQALKIPNAEQQAQRLLVDFPRQPAALGLYVRANHYLNVADRPQFQKGIYLLEQVLKLEPDNHYVQAEL
LIAYHVQQAISPDQALNQDRMLVLSEQLQQVSYSPQAVVQPRIYEALALQATVENQVETATHYLAQAQGLRESVLSYVLQ
GKHAELKGDLDGASDAYSEAFYMDTSLETYLLCENLVFHSNLKSIDYAMYRSVHPSVVRLL

Sequences:

>Translated_541_residues
MCGARAYSASYRCYLPDTKSYSMIGICFQINDWVLCIDENKLYRQDREVSAEPRLINLLHFLAEHAGEVFGREELIQHVW
DGAIVTDQVVTQSIFELRKLLRDGREENLSYVVTVPKRGYKLVANVQRLDGNPYVSRQEESTASDVCLADDIDDVEDAVP
EIVFPAGPLTRAVCQSQQPKKSSKPNVSRWRLNLLNAIWIGLVIVAMGFFTVQQSQVRITQVVDTHLIEFKFQDGFHAQA
LTHELADGIAQKLMADLTQVSDYRVILGKTAYSSGILPGKSIMVRVNDQDGHEFLDLELKNNSSDAVLFSRQYPLDSQHL
ASVLKSAEWDVMQALKIPNAEQQAQRLLVDFPRQPAALGLYVRANHYLNVADRPQFQKGIYLLEQVLKLEPDNHYVQAEL
LIAYHVQQAISPDQALNQDRMLVLSEQLQQVSYSPQAVVQPRIYEALALQATVENQVETATHYLAQAQGLRESVLSYVLQ
GKHAELKGDLDGASDAYSEAFYMDTSLETYLLCENLVFHSNLKSIDYAMYRSVHPSVVRLL
>Mature_541_residues
MCGARAYSASYRCYLPDTKSYSMIGICFQINDWVLCIDENKLYRQDREVSAEPRLINLLHFLAEHAGEVFGREELIQHVW
DGAIVTDQVVTQSIFELRKLLRDGREENLSYVVTVPKRGYKLVANVQRLDGNPYVSRQEESTASDVCLADDIDDVEDAVP
EIVFPAGPLTRAVCQSQQPKKSSKPNVSRWRLNLLNAIWIGLVIVAMGFFTVQQSQVRITQVVDTHLIEFKFQDGFHAQA
LTHELADGIAQKLMADLTQVSDYRVILGKTAYSSGILPGKSIMVRVNDQDGHEFLDLELKNNSSDAVLFSRQYPLDSQHL
ASVLKSAEWDVMQALKIPNAEQQAQRLLVDFPRQPAALGLYVRANHYLNVADRPQFQKGIYLLEQVLKLEPDNHYVQAEL
LIAYHVQQAISPDQALNQDRMLVLSEQLQQVSYSPQAVVQPRIYEALALQATVENQVETATHYLAQAQGLRESVLSYVLQ
GKHAELKGDLDGASDAYSEAFYMDTSLETYLLCENLVFHSNLKSIDYAMYRSVHPSVVRLL

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=508, Percent_Identity=26.1811023622047, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 61124; Mature: 61124

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGARAYSASYRCYLPDTKSYSMIGICFQINDWVLCIDENKLYRQDREVSAEPRLINLLH
CCCCCCCCCCEEEECCCCCCCEEEEEEEEECCEEEEEECCHHHHHCCCCCCCCHHHHHHH
FLAEHAGEVFGREELIQHVWDGAIVTDQVVTQSIFELRKLLRDGREENLSYVVTVPKRGY
HHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
KLVANVQRLDGNPYVSRQEESTASDVCLADDIDDVEDAVPEIVFPAGPLTRAVCQSQQPK
EEEEEHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHCCCEECCCCHHHHHHHCCCCCC
KSSKPNVSRWRLNLLNAIWIGLVIVAMGFFTVQQSQVRITQVVDTHLIEFKFQDGFHAQA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHH
LTHELADGIAQKLMADLTQVSDYRVILGKTAYSSGILPGKSIMVRVNDQDGHEFLDLELK
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCCCEEEEEEECCCCCEEEEEEEC
NNSSDAVLFSRQYPLDSQHLASVLKSAEWDVMQALKIPNAEQQAQRLLVDFPRQPAALGL
CCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEE
YVRANHYLNVADRPQFQKGIYLLEQVLKLEPDNHYVQAELLIAYHVQQAISPDQALNQDR
EEEECCEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCHHHHCCCCH
MLVLSEQLQQVSYSPQAVVQPRIYEALALQATVENQVETATHYLAQAQGLRESVLSYVLQ
HHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKHAELKGDLDGASDAYSEAFYMDTSLETYLLCENLVFHSNLKSIDYAMYRSVHPSVVRL
CCCCCCCCCCCCCCHHHHHHEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHC
L
C
>Mature Secondary Structure
MCGARAYSASYRCYLPDTKSYSMIGICFQINDWVLCIDENKLYRQDREVSAEPRLINLLH
CCCCCCCCCCEEEECCCCCCCEEEEEEEEECCEEEEEECCHHHHHCCCCCCCCHHHHHHH
FLAEHAGEVFGREELIQHVWDGAIVTDQVVTQSIFELRKLLRDGREENLSYVVTVPKRGY
HHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
KLVANVQRLDGNPYVSRQEESTASDVCLADDIDDVEDAVPEIVFPAGPLTRAVCQSQQPK
EEEEEHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHCCCEECCCCHHHHHHHCCCCCC
KSSKPNVSRWRLNLLNAIWIGLVIVAMGFFTVQQSQVRITQVVDTHLIEFKFQDGFHAQA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHH
LTHELADGIAQKLMADLTQVSDYRVILGKTAYSSGILPGKSIMVRVNDQDGHEFLDLELK
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCCCEEEEEEECCCCCEEEEEEEC
NNSSDAVLFSRQYPLDSQHLASVLKSAEWDVMQALKIPNAEQQAQRLLVDFPRQPAALGL
CCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEE
YVRANHYLNVADRPQFQKGIYLLEQVLKLEPDNHYVQAELLIAYHVQQAISPDQALNQDR
EEEECCEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCHHHHCCCCH
MLVLSEQLQQVSYSPQAVVQPRIYEALALQATVENQVETATHYLAQAQGLRESVLSYVLQ
HHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKHAELKGDLDGASDAYSEAFYMDTSLETYLLCENLVFHSNLKSIDYAMYRSVHPSVVRL
CCCCCCCCCCCCCCHHHHHHEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]