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The map label for this gene is zntR [H]

Identifier: 227080491

GI number: 227080491

Start: 267492

End: 267893

Strand: Direct

Name: zntR [H]

Synonym: VCM66_0262

Alternate gene names: 227080491

Gene position: 267492-267893 (Clockwise)

Preceding gene: 227080488

Following gene: 227080492

Centisome position: 9.25

GC content: 49.75

Gene sequence:

>402_bases
GTGATGTTTCAGATTGGAGAGTTAGCCAAACGCTGCGGCGTTTCCACCGATACACTGCGTTTCTATGAAAAAAATGAGCT
GATTGCTCCGGCAACGCGCACCGAGTCGGGCTATCGACTGTACGATGAAAAGAGCCAGCAACAAGTCACGTTTATTTTAA
AAGCCAAAGAGTTAGGGCTGAGCCTCGAAGAGATTAAAGAGCTGCTGGAAATTCGTTTGGAAGCGACCGAACACAGCTGC
GCCGAGGTGAAAGCGATCACCAGCGCTAAGCTGGCGGTGATCGACCAAAAGATTGAAGAGCTGACCCGTATTCGCAGCGC
GCTGAAAAAAATCAATGATGCCTGCTGTGGACATGTCGAAGATAATGCCAGCCACTGCTCGATTTTAGCCGCGTTAGAGT
AG

Upstream 100 bases:

>100_bases
CATGGGAAAAATAATCGCTAAAAAACGGTTTTTCAAGCACAAATTTTAACGAAAGCTTAAATTTCCCCAAACTACTCCAA
GTAGTCAGGGAGGAGGAGGA

Downstream 100 bases:

>100_bases
AGAAATAACGCCTAATTTATATTCTGATTGATAAGGGTAATTTAGTTTTTACCACTAGGAATGACGTTGTCTGATGGTTA
AACAACCTAAGTTTGCAATT

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MMFQIGELAKRCGVSTDTLRFYEKNELIAPATRTESGYRLYDEKSQQQVTFILKAKELGLSLEEIKELLEIRLEATEHSC
AEVKAITSAKLAVIDQKIEELTRIRSALKKINDACCGHVEDNASHCSILAALE

Sequences:

>Translated_133_residues
MMFQIGELAKRCGVSTDTLRFYEKNELIAPATRTESGYRLYDEKSQQQVTFILKAKELGLSLEEIKELLEIRLEATEHSC
AEVKAITSAKLAVIDQKIEELTRIRSALKKINDACCGHVEDNASHCSILAALE
>Mature_133_residues
MMFQIGELAKRCGVSTDTLRFYEKNELIAPATRTESGYRLYDEKSQQQVTFILKAKELGLSLEEIKELLEIRLEATEHSC
AEVKAITSAKLAVIDQKIEELTRIRSALKKINDACCGHVEDNASHCSILAALE

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=132, Percent_Identity=45.4545454545455, Blast_Score=126, Evalue=5e-31,
Organism=Escherichia coli, GI1786695, Length=130, Percent_Identity=35.3846153846154, Blast_Score=86, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14916; Mature: 14916

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFQIGELAKRCGVSTDTLRFYEKNELIAPATRTESGYRLYDEKSQQQVTFILKAKELGL
CCCCHHHHHHHHCCCCHHHHHCCCCCEECCCCCCCCCCEECCCCCCHHHHHEEEHHHHCC
SLEEIKELLEIRLEATEHSCAEVKAITSAKLAVIDQKIEELTRIRSALKKINDACCGHVE
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DNASHCSILAALE
CCCCCEEEEEECC
>Mature Secondary Structure
MMFQIGELAKRCGVSTDTLRFYEKNELIAPATRTESGYRLYDEKSQQQVTFILKAKELGL
CCCCHHHHHHHHCCCCHHHHHCCCCCEECCCCCCCCCCEECCCCCCHHHHHEEEHHHHCC
SLEEIKELLEIRLEATEHSCAEVKAITSAKLAVIDQKIEELTRIRSALKKINDACCGHVE
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DNASHCSILAALE
CCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]