Click here to switch to the map view.

The map label for this gene is kdkA [H]

Identifier: 227080447

GI number: 227080447

Start: 217940

End: 218695

Strand: Direct

Name: kdkA [H]

Synonym: VCM66_0215

Alternate gene names: 227080447

Gene position: 217940-218695 (Clockwise)

Preceding gene: 227080443

Following gene: 227080448

Centisome position: 7.53

GC content: 46.16

Gene sequence:

>756_bases
ATGCAGAGCAAAACTGCAAAACTACCGGATAACGATAGGAATCGCCCCTTGATACAGACGTTCAACGACGCGCAGCAGAA
AGTTTGGTTTGACGACGCGCTTTTGCATGAAGACCCAAGTCAATGCTGCAACCCCGAGTTTTGGCAGCAAAATGGTAAAG
TGCTCGGAAGCGCGACAGGACGAGGCACTACGTGGTTTGTACAGTTGCAACAGACACAAGGTGCGTTGCGTCATTATCGC
CGCGGTGGTTTGTTTGGAAAGCTGGTGGCCGATTCTTACTGGTTCACCGGTTGGGAAAAGACTCGCAGCTATCAAGAATT
TATGCTGCTCAATCACTTACGCGATGCTGGCGTCAACGTACCACGCCCGATTGCCGCTCGCGTACAAAAACATGGACTGC
TGTATAAAGCCGATCTCTTAAGTGAAAAAGTGCCGAATGCCCGCGATCTGGTGAGTATCTTGCAAGAAAGCCCGATCAGC
GATGAACTCTATCGTAAAATCGGCCGTGAGATCCGCAAAATGCACGATGCGCAAGTCAACCACACCGATCTTAATATTCA
TAACATCTTGATTGATGACCAAGAGAAGGTATGGATTATTGATTTTGATAAGTGTTATGTGCAAATTGGAGATTCTTGGA
AACAAGGGAATCTCAAACGATTGAAGAGGTCGTTTGAGAAAGAAGTCTGCAAGCGAGGGATTAATTGGAGTCTTGAAGCG
TTTGCTATTATTTCTAGCTATAAACATGAAGAGTAA

Upstream 100 bases:

>100_bases
TTGAAACAATGCCATAGCCAAGCCTATTCGATAAAACTATTCGATAATTGAGCCAGAATTATGCAGAGCTGACCAGAAAA
TGTAAAATGCAGCACGCCAG

Downstream 100 bases:

>100_bases
AATATGCTATTCGATCAGATTACATTCGTAATTCAAGGACCTATTACACCGTCCATTACCTCCACATCTGTTCGACGTTT
ACGATCAATTTTCCCAGGCT

Product: 3-deoxy-D-manno-octulosonic-acid kinase

Products: NA

Alternate protein names: KDO kinase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MQSKTAKLPDNDRNRPLIQTFNDAQQKVWFDDALLHEDPSQCCNPEFWQQNGKVLGSATGRGTTWFVQLQQTQGALRHYR
RGGLFGKLVADSYWFTGWEKTRSYQEFMLLNHLRDAGVNVPRPIAARVQKHGLLYKADLLSEKVPNARDLVSILQESPIS
DELYRKIGREIRKMHDAQVNHTDLNIHNILIDDQEKVWIIDFDKCYVQIGDSWKQGNLKRLKRSFEKEVCKRGINWSLEA
FAIISSYKHEE

Sequences:

>Translated_251_residues
MQSKTAKLPDNDRNRPLIQTFNDAQQKVWFDDALLHEDPSQCCNPEFWQQNGKVLGSATGRGTTWFVQLQQTQGALRHYR
RGGLFGKLVADSYWFTGWEKTRSYQEFMLLNHLRDAGVNVPRPIAARVQKHGLLYKADLLSEKVPNARDLVSILQESPIS
DELYRKIGREIRKMHDAQVNHTDLNIHNILIDDQEKVWIIDFDKCYVQIGDSWKQGNLKRLKRSFEKEVCKRGINWSLEA
FAIISSYKHEE
>Mature_251_residues
MQSKTAKLPDNDRNRPLIQTFNDAQQKVWFDDALLHEDPSQCCNPEFWQQNGKVLGSATGRGTTWFVQLQQTQGALRHYR
RGGLFGKLVADSYWFTGWEKTRSYQEFMLLNHLRDAGVNVPRPIAARVQKHGLLYKADLLSEKVPNARDLVSILQESPIS
DELYRKIGREIRKMHDAQVNHTDLNIHNILIDDQEKVWIIDFDKCYVQIGDSWKQGNLKRLKRSFEKEVCKRGINWSLEA
FAIISSYKHEE

Specific function: ATP-dependent phosphorylation of 3-deoxy-D-manno- octulosonic acid at the 4-OH position [H]

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. KdkA/rfaP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022826
- InterPro:   IPR011009
- InterPro:   IPR010440
- InterPro:   IPR000719 [H]

Pfam domain/function: PF06293 Kdo [H]

EC number: NA

Molecular weight: Translated: 29244; Mature: 29244

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSKTAKLPDNDRNRPLIQTFNDAQQKVWFDDALLHEDPSQCCNPEFWQQNGKVLGSATG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHCCCCEEECCCC
RGTTWFVQLQQTQGALRHYRRGGLFGKLVADSYWFTGWEKTRSYQEFMLLNHLRDAGVNV
CCEEEEEEEHHHHHHHHHHHHCCCHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHCCCCC
PRPIAARVQKHGLLYKADLLSEKVPNARDLVSILQESPISDELYRKIGREIRKMHDAQVN
CCHHHHHHHHCCCEEEHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
HTDLNIHNILIDDQEKVWIIDFDKCYVQIGDSWKQGNLKRLKRSFEKEVCKRGINWSLEA
CCCCEEEEEEEECCCCEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHH
FAIISSYKHEE
HHHHHHHCCCC
>Mature Secondary Structure
MQSKTAKLPDNDRNRPLIQTFNDAQQKVWFDDALLHEDPSQCCNPEFWQQNGKVLGSATG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHCCCCEEECCCC
RGTTWFVQLQQTQGALRHYRRGGLFGKLVADSYWFTGWEKTRSYQEFMLLNHLRDAGVNV
CCEEEEEEEHHHHHHHHHHHHCCCHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHCCCCC
PRPIAARVQKHGLLYKADLLSEKVPNARDLVSILQESPISDELYRKIGREIRKMHDAQVN
CCHHHHHHHHCCCEEEHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
HTDLNIHNILIDDQEKVWIIDFDKCYVQIGDSWKQGNLKRLKRSFEKEVCKRGINWSLEA
CCCCEEEEEEEECCCCEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHH
FAIISSYKHEE
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]