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The map label for this gene is mcp4 [H]

Identifier: 227080436

GI number: 227080436

Start: 209444

End: 211138

Strand: Direct

Name: mcp4 [H]

Synonym: VCM66_0204

Alternate gene names: 227080436

Gene position: 209444-211138 (Clockwise)

Preceding gene: 227080432

Following gene: 227080437

Centisome position: 7.24

GC content: 50.44

Gene sequence:

>1695_bases
ATGAAAGGGAATCTTATGCTGTCTTCTCTACGAAGCCGTACCAAATTACTGCTATTGACGGTCATTCCTCTGATCGTCAT
TACCGCCTTGGTCATGGCGGTGAATTATCAGAGTGGGTTATCTACCTTACAAAAAGAGCTAGAAAACTACCGCACCGATC
TGATTGATGCCAAGAAAAAAGAGCTGCAAGCCTATCTCATGATGGGGGTGACGGCGGTGAAACCCTTATATGAGAGTGAT
AAAGCCGGTGAAAACCAAGCGCAAGCCAAACAAATCCTCAAAGCGATGCGTTTTGACAGCGATGGCTATTTCTTTGCTTA
CGACTCACAAGGGGTCAATACCCTACATGCGATTAAGCCTGAATTAGAAGGCAAAAACCTCTACGGCATGAAAGATGAAA
ATGGTGTGGCGGTGATTGCTGGCTTAATTGATGCCTCGAAAACGGGCGATGGATTCCTCTATTTCTCTTGGCACAAACCG
ACGATTAATGCGCAAGCGCCGAAACTGGGTTATGCCGAATACCTGCCGAAATGGGATTGGGTATTGGGGACGGGCATCTA
TATTGATGATGTCGATACCCAAGTGGCAGAGTTTCGCGCGCAGCGCGAGGCGGATCTCTACGATCAAATGATCTCCGCGA
TTGGGCTTTCGGTTGTCGGTTTGGTGTTCACTATTATTGCGGTGAGTGTTTTGGTGTCTCGCGGCATTGCACCACTGCAA
CATGTGGTGAGTTCACTACAGGCGGTGGCTGCGGGTGGCGGCGATTTAACCGCGCGGATTAAAGTTGAGAGCCAAGATGA
GATTGGCGATGTAGCGAAGGCGTTTAACGCCTTTATGGATAAGCTGCATCCGCTTATGACTGATATCCGCGCCTCGGCCA
ATACGGTCGAAGCGGCTGCGCAGGAATTGGATCAACAAACCTCGCAAGCCAGCCATAAGATGGACGGTCACTGTTTAGAG
ACCGATAAAGTTGTCGCTGCGGTGACTGAAATGAGCGCCACGGCGCGCGAAGTGGCGAGCAACACTTACTCGACCGCGCA
AGCGATTGAGTCGGCTAACAGCCAAATTGCTGTCGCGCAGAAAGAGGTGAATCTGGCGATTGATGGGATTGGTGAGTTGG
TCAACGAAGTGAACCAAACCTCTGCTGCGGTAGGCGATCTCAGCCAACAGGCGGCGAAGATCACCCAAGTGCTGAAAGTG
ATTGGCGATATTGCTGAGCAAACCAATTTACTGGCACTGAATGCGGCGATTGAAGCGGCGCGAGCGGGTGAACAGGGGCG
CGGCTTTGCTGTGGTGGCCGATGAAGTACGCTCACTGGCGAGTCGTACTCAAAATAGCACTAAAGAGATTGGTGAAATGC
TCAATGCGCTGCACCAAGGGGTCAGTAAAGCGGTGCAGAGCATGAACATCAGCCAAGAGCGTGGTGAGAAAACCGCGCTG
GAATCGGTGCAGATTAAAGAGAGCTTAGCGGGGATCTCCAAAGCAGTAAGCCTAATTCATGATATGGGCATTCAGACGGC
TTCTGCGGCTGAGCAGCAAAGCGCCGTAGCAGAAGACATCAACCAAAATCTGGTCGCGATTCAGCAGATCGTCAATGAAC
TTAGTGAAAGCTTTAAACAGACCGAAAGCGTTAGCGCAAGTTTGTCCCATTCTGGACAACAGATGGGCACTTTGGTTGGG
CATTTTAAGCTTTAA

Upstream 100 bases:

>100_bases
GCCGCTGTGCATCGCGCCACTGGTCGAGCTGCAAAGCATCGGTCATTTCACAGACAATAGACCATGAATATGAGATAAGT
CATTCACAAAGCTAACAATA

Downstream 100 bases:

>100_bases
TCAACAGTGAAATTGCATTGCCGCTTGAGGTGATTCGAAACTTTATTAGGGCCGCTTGCGGCCCTTTGCTTTCTCTGTTT
TGTGTAAGCAAAACCGACCC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MKGNLMLSSLRSRTKLLLLTVIPLIVITALVMAVNYQSGLSTLQKELENYRTDLIDAKKKELQAYLMMGVTAVKPLYESD
KAGENQAQAKQILKAMRFDSDGYFFAYDSQGVNTLHAIKPELEGKNLYGMKDENGVAVIAGLIDASKTGDGFLYFSWHKP
TINAQAPKLGYAEYLPKWDWVLGTGIYIDDVDTQVAEFRAQREADLYDQMISAIGLSVVGLVFTIIAVSVLVSRGIAPLQ
HVVSSLQAVAAGGGDLTARIKVESQDEIGDVAKAFNAFMDKLHPLMTDIRASANTVEAAAQELDQQTSQASHKMDGHCLE
TDKVVAAVTEMSATAREVASNTYSTAQAIESANSQIAVAQKEVNLAIDGIGELVNEVNQTSAAVGDLSQQAAKITQVLKV
IGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQNSTKEIGEMLNALHQGVSKAVQSMNISQERGEKTAL
ESVQIKESLAGISKAVSLIHDMGIQTASAAEQQSAVAEDINQNLVAIQQIVNELSESFKQTESVSASLSHSGQQMGTLVG
HFKL

Sequences:

>Translated_564_residues
MKGNLMLSSLRSRTKLLLLTVIPLIVITALVMAVNYQSGLSTLQKELENYRTDLIDAKKKELQAYLMMGVTAVKPLYESD
KAGENQAQAKQILKAMRFDSDGYFFAYDSQGVNTLHAIKPELEGKNLYGMKDENGVAVIAGLIDASKTGDGFLYFSWHKP
TINAQAPKLGYAEYLPKWDWVLGTGIYIDDVDTQVAEFRAQREADLYDQMISAIGLSVVGLVFTIIAVSVLVSRGIAPLQ
HVVSSLQAVAAGGGDLTARIKVESQDEIGDVAKAFNAFMDKLHPLMTDIRASANTVEAAAQELDQQTSQASHKMDGHCLE
TDKVVAAVTEMSATAREVASNTYSTAQAIESANSQIAVAQKEVNLAIDGIGELVNEVNQTSAAVGDLSQQAAKITQVLKV
IGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQNSTKEIGEMLNALHQGVSKAVQSMNISQERGEKTAL
ESVQIKESLAGISKAVSLIHDMGIQTASAAEQQSAVAEDINQNLVAIQQIVNELSESFKQTESVSASLSHSGQQMGTLVG
HFKL
>Mature_564_residues
MKGNLMLSSLRSRTKLLLLTVIPLIVITALVMAVNYQSGLSTLQKELENYRTDLIDAKKKELQAYLMMGVTAVKPLYESD
KAGENQAQAKQILKAMRFDSDGYFFAYDSQGVNTLHAIKPELEGKNLYGMKDENGVAVIAGLIDASKTGDGFLYFSWHKP
TINAQAPKLGYAEYLPKWDWVLGTGIYIDDVDTQVAEFRAQREADLYDQMISAIGLSVVGLVFTIIAVSVLVSRGIAPLQ
HVVSSLQAVAAGGGDLTARIKVESQDEIGDVAKAFNAFMDKLHPLMTDIRASANTVEAAAQELDQQTSQASHKMDGHCLE
TDKVVAAVTEMSATAREVASNTYSTAQAIESANSQIAVAQKEVNLAIDGIGELVNEVNQTSAAVGDLSQQAAKITQVLKV
IGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQNSTKEIGEMLNALHQGVSKAVQSMNISQERGEKTAL
ESVQIKESLAGISKAVSLIHDMGIQTASAAEQQSAVAEDINQNLVAIQQIVNELSESFKQTESVSASLSHSGQQMGTLVG
HFKL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=302, Percent_Identity=33.112582781457, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1787690, Length=351, Percent_Identity=28.4900284900285, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788195, Length=279, Percent_Identity=31.5412186379928, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1789453, Length=222, Percent_Identity=33.7837837837838, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788194, Length=333, Percent_Identity=27.6276276276276, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60491; Mature: 60491

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGNLMLSSLRSRTKLLLLTVIPLIVITALVMAVNYQSGLSTLQKELENYRTDLIDAKKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELQAYLMMGVTAVKPLYESDKAGENQAQAKQILKAMRFDSDGYFFAYDSQGVNTLHAIKP
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCC
ELEGKNLYGMKDENGVAVIAGLIDASKTGDGFLYFSWHKPTINAQAPKLGYAEYLPKWDW
CCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHCCCCCH
VLGTGIYIDDVDTQVAEFRAQREADLYDQMISAIGLSVVGLVFTIIAVSVLVSRGIAPLQ
HEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HVVSSLQAVAAGGGDLTARIKVESQDEIGDVAKAFNAFMDKLHPLMTDIRASANTVEAAA
HHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
QELDQQTSQASHKMDGHCLETDKVVAAVTEMSATAREVASNTYSTAQAIESANSQIAVAQ
HHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEH
KEVNLAIDGIGELVNEVNQTSAAVGDLSQQAAKITQVLKVIGDIAEQTNLLALNAAIEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHH
RAGEQGRGFAVVADEVRSLASRTQNSTKEIGEMLNALHQGVSKAVQSMNISQERGEKTAL
HCCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHHH
ESVQIKESLAGISKAVSLIHDMGIQTASAAEQQSAVAEDINQNLVAIQQIVNELSESFKQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TESVSASLSHSGQQMGTLVGHFKL
HHHHHHHHHHCHHHHHHHHHHCCC
>Mature Secondary Structure
MKGNLMLSSLRSRTKLLLLTVIPLIVITALVMAVNYQSGLSTLQKELENYRTDLIDAKKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELQAYLMMGVTAVKPLYESDKAGENQAQAKQILKAMRFDSDGYFFAYDSQGVNTLHAIKP
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCC
ELEGKNLYGMKDENGVAVIAGLIDASKTGDGFLYFSWHKPTINAQAPKLGYAEYLPKWDW
CCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHCCCCCH
VLGTGIYIDDVDTQVAEFRAQREADLYDQMISAIGLSVVGLVFTIIAVSVLVSRGIAPLQ
HEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HVVSSLQAVAAGGGDLTARIKVESQDEIGDVAKAFNAFMDKLHPLMTDIRASANTVEAAA
HHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
QELDQQTSQASHKMDGHCLETDKVVAAVTEMSATAREVASNTYSTAQAIESANSQIAVAQ
HHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEH
KEVNLAIDGIGELVNEVNQTSAAVGDLSQQAAKITQVLKVIGDIAEQTNLLALNAAIEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHH
RAGEQGRGFAVVADEVRSLASRTQNSTKEIGEMLNALHQGVSKAVQSMNISQERGEKTAL
HCCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHHH
ESVQIKESLAGISKAVSLIHDMGIQTASAAEQQSAVAEDINQNLVAIQQIVNELSESFKQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TESVSASLSHSGQQMGTLVGHFKL
HHHHHHHHHHCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]