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The map label for this gene is ftsY [H]

Identifier: 227080382

GI number: 227080382

Start: 136919

End: 138100

Strand: Direct

Name: ftsY [H]

Synonym: VCM66_0147

Alternate gene names: 227080382

Gene position: 136919-138100 (Clockwise)

Preceding gene: 227080379

Following gene: 227080383

Centisome position: 4.73

GC content: 49.58

Gene sequence:

>1182_bases
ATGACGGAAAAAAAGAAGCGTGGCTTGTTGTCATGGCTTGGATTTGGTGACGAAGAGAAAAGCCAAACCACTGCAACGGA
TACTCAAACGCAGGATGAACCACAAAGCCAAGCCGATGTTGAAGCGGTGGCGATTCAAACGGAAACTGCGTTAACAGAAA
CAGAAACAGAAACAGAAACAGAAACAGAAACAGAAACAGAAACAGAAACAGAAACAGCCACGGTTGAACCTGCACGTATT
GTTGAACAAGAGAAACCGACCGAAAGTTTCTTTGCGCGCTTAAAGCGCAGTTTGAGCCGCACCAAAGCGAATATTGGCGC
TGGCTTCTTTGGCCTGTTTAAAGGCAAAAAGATTGATGATGACCTGTTCGAAGAGCTCGAAGAACAACTGCTGATTGCCG
ATGTCGGCATGGATACGACCAGCAAAATCATCGCTAATTTGACCGCCAGAGCTTCTCGCCAGCAACTGCGTGATGGGGAA
GCGCTGTACGGTCTGCTGAAAGAAGAGATGGCCGAGATTCTCTCTCAGGTCGAGCAGCCATTGGTGATCGACACTGAGAA
AAAACCTTACGTGATCTTGATGGTGGGCGTGAATGGGGTGGGTAAAACTACCACGATCGGTAAACTGGCTAAACAGTTCC
AAGCGCAAGGCAAGAAAGTGATGTTGGCAGCGGGCGATACCTTCCGTGCTGCAGCGGTTGAGCAGTTGCAAGTGTGGGGA
GAGCGCAATCAAGTGCCTGTCATCGCTCAGCATACTGGCGCCGACAGTGCCTCCGTCATTTATGATGCGATTGAAGCGGC
GAAAGCGCGCGGGATTGACGTGGTGATTGCGGATACCGCAGGCCGTCTGCAAAACAAAAGTAACCTGATGGAAGAGCTGC
GCAAGATTGTGCGCGTGATGAAGAAGATTGATGACAGTGCGCCACATGAAATCATGTTGACGCTGGATGCGGGTACCGGA
CAAAACGCGATCAGTCAGGCCAAATTGTTTAGTGATGTAGCGCCCATCACGGGCATTACCTTAACTAAGCTTGATGGCAC
CGCTAAAGGTGGCGTGATTTTCGCGATTGCCGATCAATTCCAGATCCCAATCCGTTATATCGGTGTCGGCGAGAAAATTG
ACGACTTACGTCCATTTGCAACACAAGAGTTTATCGACGCGCTATTTAGCCGCGAAGAATAA

Upstream 100 bases:

>100_bases
AGCAAAAAGTTTTCACTGCTTTGTCATTTTTTCTTTTCGGGGCCGCAATAATGGCCAAGAAAAGTCTGTATTAAAATAAA
GCGATTCAGGATAGCTCCAG

Downstream 100 bases:

>100_bases
ACCAATCTCAGTTGGCACAGTGTGCCAGCCTTGTCAGGGGGAGACGGCGTGATCAGGTTTCAGCAAGTCAGTAAAGCGTA
TCGAGGTGGACGACAAGCGC

Product: cell division protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETETETETETETETETATVEPARI
VEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDLFEELEEQLLIADVGMDTTSKIIANLTARASRQQLRDGE
ALYGLLKEEMAEILSQVEQPLVIDTEKKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWG
ERNQVPVIAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLDAGTG
QNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIADQFQIPIRYIGVGEKIDDLRPFATQEFIDALFSREE

Sequences:

>Translated_393_residues
MTEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETETETETETETETETATVEPARI
VEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDLFEELEEQLLIADVGMDTTSKIIANLTARASRQQLRDGE
ALYGLLKEEMAEILSQVEQPLVIDTEKKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWG
ERNQVPVIAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLDAGTG
QNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIADQFQIPIRYIGVGEKIDDLRPFATQEFIDALFSREE
>Mature_392_residues
TEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETETETETETETETETATVEPARIV
EQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDLFEELEEQLLIADVGMDTTSKIIANLTARASRQQLRDGEA
LYGLLKEEMAEILSQVEQPLVIDTEKKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWGE
RNQVPVIAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLDAGTGQ
NAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIADQFQIPIRYIGVGEKIDDLRPFATQEFIDALFSREE

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=271, Percent_Identity=32.1033210332103, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226371618, Length=205, Percent_Identity=37.0731707317073, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI23308697, Length=333, Percent_Identity=27.9279279279279, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI295424842, Length=333, Percent_Identity=27.9279279279279, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=33.5664335664336, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1789874, Length=313, Percent_Identity=78.2747603833866, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI1788963, Length=298, Percent_Identity=32.2147651006711, Blast_Score=148, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17539958, Length=205, Percent_Identity=31.219512195122, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI193206261, Length=320, Percent_Identity=30, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=212, Percent_Identity=35.8490566037736, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320498, Length=231, Percent_Identity=31.1688311688312, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17647949, Length=280, Percent_Identity=33.5714285714286, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24641198, Length=407, Percent_Identity=27.5184275184275, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 43035; Mature: 42904

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETET
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCC
ETETETETETETATVEPARIVEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKKIDD
CCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCH
DLFEELEEQLLIADVGMDTTSKIIANLTARASRQQLRDGEALYGLLKEEMAEILSQVEQP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
LVIDTEKKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWG
EEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHC
ERNQVPVIAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVM
CCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHHH
KKIDDSAPHEIMLTLDAGTGQNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIADQF
HHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCC
QIPIRYIGVGEKIDDLRPFATQEFIDALFSREE
CCCEEEEECCCCHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETET
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCC
ETETETETETETATVEPARIVEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKKIDD
CCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCH
DLFEELEEQLLIADVGMDTTSKIIANLTARASRQQLRDGEALYGLLKEEMAEILSQVEQP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
LVIDTEKKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWG
EEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHC
ERNQVPVIAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVM
CCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHHH
KKIDDSAPHEIMLTLDAGTGQNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIADQF
HHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCC
QIPIRYIGVGEKIDDLRPFATQEFIDALFSREE
CCCEEEEECCCCHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]