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The map label for this gene is infC [H]

Identifier: 226950567

GI number: 226950567

Start: 3579305

End: 3579859

Strand: Reverse

Name: infC [H]

Synonym: CLM_3544

Alternate gene names: 226950567

Gene position: 3579859-3579305 (Counterclockwise)

Preceding gene: 226950568

Following gene: 226950566

Centisome position: 86.15

GC content: 30.81

Gene sequence:

>555_bases
TTGTTAAGTGTTTTCGGTCTAATATTTTTGGAGGTGAAGATTATTAACAAAAACTATCTTATGAATGAGCAAATCCGTGA
AAGAGAAGTAAGACTTGTAGGTAGCGAGGGAGAACAATTAGGAGTAGTGTCTTCAAGTGAGGCGCAAAAGCTTGCAGATG
AAAAGGAACTAGACTTAGTACTTATAGCTCCAACTGCAAAACCACCAGTTTGTAAAATAATGAATTATGGTAAATTCTTA
TATGAACAAACTAAAAAAGACAAAGAAGCTAAAAAGAATCAAAAGGTTATAAACATAAAAGAAGTTAGACTAAGCCCAAC
TATAGAAGCACATGACATAGAAATTAAAGCTAATAATGCTAGAAAATTTTTAAATGCAGGAAATAAAGTTAAAGTAACTG
TTAGATTCAGAGGTAGAGAAGCTGATTATTCCTTTAAAGGAAATAAAATATTAAAATCCTTTTATGAAAAAGTAGAAGAA
CTTAGTGTTATGGAAAAAGCACCTAAACTAGAAGGAAGAAATATGATAATGATATTAGCGCCAAGAAAAGCGTAA

Upstream 100 bases:

>100_bases
ACCTTACAGCATGGCTAGTAAGGTTAGAGTATATAAATTTAATTTGTATTATTGTTTATGAAGACGGCTTATGCCGTCTT
TTATTTATTATACATGAAAA

Downstream 100 bases:

>100_bases
TAACGAGGGGAGGAAATCACAATGCCAAAAATGAAAACAAAAAGGGCTGCAGCAAAGAGATTTAAAGTAACTGGAACAGG
TAAGTTAAAGAGAGCTAAAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MLSVFGLIFLEVKIINKNYLMNEQIREREVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVCKIMNYGKFL
YEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVKVTVRFRGREADYSFKGNKILKSFYEKVEE
LSVMEKAPKLEGRNMIMILAPRKA

Sequences:

>Translated_184_residues
MLSVFGLIFLEVKIINKNYLMNEQIREREVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVCKIMNYGKFL
YEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVKVTVRFRGREADYSFKGNKILKSFYEKVEE
LSVMEKAPKLEGRNMIMILAPRKA
>Mature_184_residues
MLSVFGLIFLEVKIINKNYLMNEQIREREVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVCKIMNYGKFL
YEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVKVTVRFRGREADYSFKGNKILKSFYEKVEE
LSVMEKAPKLEGRNMIMILAPRKA

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=50.609756097561, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 21029; Mature: 21029

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVFGLIFLEVKIINKNYLMNEQIREREVRLVGSEGEQLGVVSSSEAQKLADEKELDLV
CCHHHEEEEEEEEEECCCCCCCHHHHHCEEEEECCCCCEEEEEECCHHHHHCCCCCCCEE
LIAPTAKPPVCKIMNYGKFLYEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEEEEEECCH
RKFLNAGNKVKVTVRFRGREADYSFKGNKILKSFYEKVEELSVMEKAPKLEGRNMIMILA
HHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
PRKA
CCCC
>Mature Secondary Structure
MLSVFGLIFLEVKIINKNYLMNEQIREREVRLVGSEGEQLGVVSSSEAQKLADEKELDLV
CCHHHEEEEEEEEEECCCCCCCHHHHHCEEEEECCCCCEEEEEECCHHHHHCCCCCCCEE
LIAPTAKPPVCKIMNYGKFLYEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEEEEEECCH
RKFLNAGNKVKVTVRFRGREADYSFKGNKILKSFYEKVEELSVMEKAPKLEGRNMIMILA
HHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
PRKA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]