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The map label for this gene is speA [H]

Identifier: 226950547

GI number: 226950547

Start: 3555117

End: 3556577

Strand: Direct

Name: speA [H]

Synonym: CLM_3523

Alternate gene names: 226950547

Gene position: 3555117-3556577 (Clockwise)

Preceding gene: 226950521

Following gene: 226950555

Centisome position: 85.56

GC content: 31.96

Gene sequence:

>1461_bases
GTGTATAAATTAAATCAAAATGAAACCCCAGTTTTTGATGCTTTAATGGAGTATGTAAATAGAAAAACTATTCCATTTCA
TGTTCCTGGTCACAAAAAAGGTGTAGGAATGGACGAAGCATTTAAAAATTTCATAGGAGAAAATCCTTTTAAAATTGATG
TAACTGTATTTAAATTAGTTGATAGTTTACATCATCCAACTGGTGCTATAAAAAAAGCTCAAGAATTAGCAGCTGATGCT
TATGGATCAGATGCAGCATTTTTTTCAATCCATGGTACTTCAGGCGCCATACAAGCCATGATTTTATCTGTAGTTGGTGA
TGGAGATAAAATTATAATTCCAAGAAATGTTCATAAATCTGTTACTGCCGGTATTATATTAAGTGGCTCAGTACCTGTTT
ATATGCAACCCGAGCTAGATAAAAAAGTAGGAATAGCTCACAATGTTACACCAGAAACTGTTGAAAAGACCTTAAAGGAG
AATCCTGACGCAAAAGCAGTTTTGATAATAAATCCAACTTATTATGGTGTGTCTACAGATATAAAAAAAATTGCAGAAAT
TGTTCATAGTTATAATATCCCTTTAATTGTAGATGAAGCTCATGGACCACACCTTGGTTTTAATGATAGATTACCTATAT
CTGCTATGGAAGCTGGAGCTGATATGTGTGCTCAAAGCACTCACAAAATAATAGGCGCTTTAACTCAATGCTCTTTGCTT
CAAGTAAAATCTAAGAGAATAGATGTAAATAGAGTTCATCAAGTATTAAGTTTACTTCAAACTACATCTCCATCTTATAT
ATTAATGGCTTCTTTAGATTGTTCTAGAAGACAAATAGCTTTAGAGGGTAAAGAACTTTTAGATAAAGCTATAGATTTGG
CAACCTATGCTAGAGATGAAATTAATAAAATTCCTGGTTTTTACTGCTTCGGTAAGGAATTATTGGGTAAACCTGGGGTA
TATGCTTTAGATCCTACAAAGATTACTATTAACTGTAGAGATCTAGGTATAACTGGCTATGATCTGGATATGCTTTTATG
TGAAAAATATCATATTCAAGTTGAATTATCAGATTTATACAATGTTCTCGCTGTAGGTTCTTTTGGAGATACTCAAGAAT
CTATTGATGCTTTAATAAATGCATTAAAAGAAATTAGTAATGAGCATTATGGAAAAGGAACAAAACAAAATAGTTTTATA
GATGTTCCTGAAATACCTGAAAACACAGCTGCTCCGAGAAAAGCTTTTAATGGTGTTAAGGAATGTGTACTTTTAAAAGA
TAGTATAGGAAAAGTAAGTGGAGAATTTTTAATGGCTTATCCGCCAGGAATTCCAGTATTATGTCCTGGGGAGATAATAA
CACAGGAAATTATAGATTATGTGAAAAAACTAAAAGAGACAGGATTATATGTACAAGGTACAGAAGATCCTGAGGTTGAA
TATATAAAAATTGTAAAATAA

Upstream 100 bases:

>100_bases
TTAACTTATAATAGTATTGTTTTAAGTAAAGAATCCACGGGAACCATTGAGCTTTCATAGTTTCACGGGAGTATTATTAT
GAAAGAAGGTGCATATTACG

Downstream 100 bases:

>100_bases
GAGTGGACAAAGGGCCTATTTGAAAAACTATGTTTATGAAATTTTTGAAATTGTGAATCTTATTTTAAAATAAAAAATCT
ATGAAATATGTGCTTAACGC

Product: Orn/Lys/Arg decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MYKLNQNETPVFDALMEYVNRKTIPFHVPGHKKGVGMDEAFKNFIGENPFKIDVTVFKLVDSLHHPTGAIKKAQELAADA
YGSDAAFFSIHGTSGAIQAMILSVVGDGDKIIIPRNVHKSVTAGIILSGSVPVYMQPELDKKVGIAHNVTPETVEKTLKE
NPDAKAVLIINPTYYGVSTDIKKIAEIVHSYNIPLIVDEAHGPHLGFNDRLPISAMEAGADMCAQSTHKIIGALTQCSLL
QVKSKRIDVNRVHQVLSLLQTTSPSYILMASLDCSRRQIALEGKELLDKAIDLATYARDEINKIPGFYCFGKELLGKPGV
YALDPTKITINCRDLGITGYDLDMLLCEKYHIQVELSDLYNVLAVGSFGDTQESIDALINALKEISNEHYGKGTKQNSFI
DVPEIPENTAAPRKAFNGVKECVLLKDSIGKVSGEFLMAYPPGIPVLCPGEIITQEIIDYVKKLKETGLYVQGTEDPEVE
YIKIVK

Sequences:

>Translated_486_residues
MYKLNQNETPVFDALMEYVNRKTIPFHVPGHKKGVGMDEAFKNFIGENPFKIDVTVFKLVDSLHHPTGAIKKAQELAADA
YGSDAAFFSIHGTSGAIQAMILSVVGDGDKIIIPRNVHKSVTAGIILSGSVPVYMQPELDKKVGIAHNVTPETVEKTLKE
NPDAKAVLIINPTYYGVSTDIKKIAEIVHSYNIPLIVDEAHGPHLGFNDRLPISAMEAGADMCAQSTHKIIGALTQCSLL
QVKSKRIDVNRVHQVLSLLQTTSPSYILMASLDCSRRQIALEGKELLDKAIDLATYARDEINKIPGFYCFGKELLGKPGV
YALDPTKITINCRDLGITGYDLDMLLCEKYHIQVELSDLYNVLAVGSFGDTQESIDALINALKEISNEHYGKGTKQNSFI
DVPEIPENTAAPRKAFNGVKECVLLKDSIGKVSGEFLMAYPPGIPVLCPGEIITQEIIDYVKKLKETGLYVQGTEDPEVE
YIKIVK
>Mature_486_residues
MYKLNQNETPVFDALMEYVNRKTIPFHVPGHKKGVGMDEAFKNFIGENPFKIDVTVFKLVDSLHHPTGAIKKAQELAADA
YGSDAAFFSIHGTSGAIQAMILSVVGDGDKIIIPRNVHKSVTAGIILSGSVPVYMQPELDKKVGIAHNVTPETVEKTLKE
NPDAKAVLIINPTYYGVSTDIKKIAEIVHSYNIPLIVDEAHGPHLGFNDRLPISAMEAGADMCAQSTHKIIGALTQCSLL
QVKSKRIDVNRVHQVLSLLQTTSPSYILMASLDCSRRQIALEGKELLDKAIDLATYARDEINKIPGFYCFGKELLGKPGV
YALDPTKITINCRDLGITGYDLDMLLCEKYHIQVELSDLYNVLAVGSFGDTQESIDALINALKEISNEHYGKGTKQNSFI
DVPEIPENTAAPRKAFNGVKECVLLKDSIGKVSGEFLMAYPPGIPVLCPGEIITQEIIDYVKKLKETGLYVQGTEDPEVE
YIKIVK

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=400, Percent_Identity=27.5, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786384, Length=573, Percent_Identity=25.130890052356, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1790573, Length=573, Percent_Identity=25.6544502617801, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI87082193, Length=330, Percent_Identity=26.3636363636364, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786909, Length=305, Percent_Identity=24.9180327868852, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 53329; Mature: 53329

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLNQNETPVFDALMEYVNRKTIPFHVPGHKKGVGMDEAFKNFIGENPFKIDVTVFKLV
CCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHH
DSLHHPTGAIKKAQELAADAYGSDAAFFSIHGTSGAIQAMILSVVGDGDKIIIPRNVHKS
HHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEECCCCCCC
VTAGIILSGSVPVYMQPELDKKVGIAHNVTPETVEKTLKENPDAKAVLIINPTYYGVSTD
CEEEEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCHH
IKKIAEIVHSYNIPLIVDEAHGPHLGFNDRLPISAMEAGADMCAQSTHKIIGALTQCSLL
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVKSKRIDVNRVHQVLSLLQTTSPSYILMASLDCSRRQIALEGKELLDKAIDLATYARDE
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHEEECCHHHHHHHHHHHHHHHHH
INKIPGFYCFGKELLGKPGVYALDPTKITINCRDLGITGYDLDMLLCEKYHIQVELSDLY
HHHCCCEEEECHHHCCCCCEEEECCEEEEEEEEEECCCCCCHHHHEEEEEEEEEEHHHHH
NVLAVGSFGDTQESIDALINALKEISNEHYGKGTKQNSFIDVPEIPENTAAPRKAFNGVK
HHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHH
ECVLLKDSIGKVSGEFLMAYPPGIPVLCPGEIITQEIIDYVKKLKETGLYVQGTEDPEVE
HHHHHHHHHCCCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
YIKIVK
EEEEEC
>Mature Secondary Structure
MYKLNQNETPVFDALMEYVNRKTIPFHVPGHKKGVGMDEAFKNFIGENPFKIDVTVFKLV
CCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHH
DSLHHPTGAIKKAQELAADAYGSDAAFFSIHGTSGAIQAMILSVVGDGDKIIIPRNVHKS
HHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEECCCCCCC
VTAGIILSGSVPVYMQPELDKKVGIAHNVTPETVEKTLKENPDAKAVLIINPTYYGVSTD
CEEEEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCHH
IKKIAEIVHSYNIPLIVDEAHGPHLGFNDRLPISAMEAGADMCAQSTHKIIGALTQCSLL
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVKSKRIDVNRVHQVLSLLQTTSPSYILMASLDCSRRQIALEGKELLDKAIDLATYARDE
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHEEECCHHHHHHHHHHHHHHHHH
INKIPGFYCFGKELLGKPGVYALDPTKITINCRDLGITGYDLDMLLCEKYHIQVELSDLY
HHHCCCEEEECHHHCCCCCEEEECCEEEEEEEEEECCCCCCHHHHEEEEEEEEEEHHHHH
NVLAVGSFGDTQESIDALINALKEISNEHYGKGTKQNSFIDVPEIPENTAAPRKAFNGVK
HHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHH
ECVLLKDSIGKVSGEFLMAYPPGIPVLCPGEIITQEIIDYVKKLKETGLYVQGTEDPEVE
HHHHHHHHHCCCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
YIKIVK
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]