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The map label for this gene is yisV [H]

Identifier: 226950505

GI number: 226950505

Start: 3501331

End: 3502749

Strand: Reverse

Name: yisV [H]

Synonym: CLM_3481

Alternate gene names: 226950505

Gene position: 3502749-3501331 (Counterclockwise)

Preceding gene: 226950506

Following gene: 226950504

Centisome position: 84.3

GC content: 24.52

Gene sequence:

>1419_bases
ATGGAGAAATATATATTAATTTTTCAGGAGAACTCTATACCTAAATATGTTCAACTATATAAATACATAAAAAATATGAT
AGATAAAAATAAAATTAAAGATAATGAAAAGCTGCCATCTATAAGAAAATTATCAAATTTATTAGCTATAAATACAGTAA
CTGTAATAAATGCATATAAAAAATTAGAGAATGATGGATATGCAATACAAAAAATAGGTAGTGGTACCTATGCAAAGAAA
AAAGAAATTAGTAGGAATTTAAGAAAAGAATATTCAGATTCAATAAAATCCATAGGTAAGGAAGAATTTAAAGCCTATAT
AGATTTTATAGGGGAAAGTGCTTGTTCAGATTTATTTCCCGTGGAATCTTTTAAATCTATATTAAATGAAGTTCTGGACA
GGGATGGAAAGGATGCTTTAGTTTATCAGGAAACATTAGGGTTCGAAGGACTTAGAAAGCATATATCAGAAGTATTCTGG
AATAACAAAATAGAAAAAAATCATATACTTATAGTTTCAGGAGCACAACAAGGAATTGATATAATATCGAAATCTATTAT
AAATGTTAATGATAATGTTTTAATAGAAAAACCTACATATAGTGGAGCGCTTTCAGTTTTTAAATGGAGAAGAGCGAACA
TATATGAAGTTCCTATGGAAGAGGATGGCGTAAATATAAAAGAATTAGAAAAGATAGTTAAAAAAAATAATATTAAATGT
TTTTATACTATGAGCTATTTTCAAAATCCAACAGGTATAAGCTGTAGTTTAGAAAAGAAAAAAGCCATATTAAATTTAGC
AACTATATATGATTTTTATATAATAGAAGACGATTATTTATCTGAATTAATATATGATAAAAGTATTCAATACATAACCT
TTAAAAGTTTGGATAGAAATGATAGAGTTATATATATAAAAAGTTTTTCAAAAATATTCTTACCTGGAATAAGAATAGGT
TACGTAATAGCGCCTAAAGACTTAAGGGAGCAAATTCAAAATTGTAAAATAAATACAGATATATCCACATCAAGTTTAAT
GCAAAGAGCTTTAGATTTGTATTTAATAAAGGGATTATGGAAGGAATATATAGATTATTTATATAAAATTTATGTACCTA
AATATGAATTTACTAAAAATACTATCCAAGATATATTAAAAAATAAAGTAGAATTACAAAATCCAGGGGGAGGGCTTCAC
TTTTATATAAAAATAAAGGAGAATGCTAATATAAATTCTATGGAACTTTTCAATGAATGTATGAAAAATAAAGTTTTAAT
TACACCAGGAGTGCTTTTTTATAAAAATCCTAAGGATGGCTTAAAATATTTTAGATTAGGATTTTCAGAGAACAGTATAG
AAGAAATAGAATTAGGTATAAAAAAAATAAATCATATATTAGAAAAAAGATTAAATTAA

Upstream 100 bases:

>100_bases
AAAATTTTATTTTTTATAAGTAAATTTGATCTAAAATTAAGAAGTACTTCGCAACTAAATAGGTTTTTTAGGTAATTAAA
AATATATGGGGGACAGTTTT

Downstream 100 bases:

>100_bases
TATATAGATCCATTGTTCTTATGAATTTATATATATTAATTAAAAAAGATTTATATTAAGCTAAGTGTTTTAAGAAAGGT
GAGGAGTATGAATAAAAATT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MEKYILIFQENSIPKYVQLYKYIKNMIDKNKIKDNEKLPSIRKLSNLLAINTVTVINAYKKLENDGYAIQKIGSGTYAKK
KEISRNLRKEYSDSIKSIGKEEFKAYIDFIGESACSDLFPVESFKSILNEVLDRDGKDALVYQETLGFEGLRKHISEVFW
NNKIEKNHILIVSGAQQGIDIISKSIINVNDNVLIEKPTYSGALSVFKWRRANIYEVPMEEDGVNIKELEKIVKKNNIKC
FYTMSYFQNPTGISCSLEKKKAILNLATIYDFYIIEDDYLSELIYDKSIQYITFKSLDRNDRVIYIKSFSKIFLPGIRIG
YVIAPKDLREQIQNCKINTDISTSSLMQRALDLYLIKGLWKEYIDYLYKIYVPKYEFTKNTIQDILKNKVELQNPGGGLH
FYIKIKENANINSMELFNECMKNKVLITPGVLFYKNPKDGLKYFRLGFSENSIEEIELGIKKINHILEKRLN

Sequences:

>Translated_472_residues
MEKYILIFQENSIPKYVQLYKYIKNMIDKNKIKDNEKLPSIRKLSNLLAINTVTVINAYKKLENDGYAIQKIGSGTYAKK
KEISRNLRKEYSDSIKSIGKEEFKAYIDFIGESACSDLFPVESFKSILNEVLDRDGKDALVYQETLGFEGLRKHISEVFW
NNKIEKNHILIVSGAQQGIDIISKSIINVNDNVLIEKPTYSGALSVFKWRRANIYEVPMEEDGVNIKELEKIVKKNNIKC
FYTMSYFQNPTGISCSLEKKKAILNLATIYDFYIIEDDYLSELIYDKSIQYITFKSLDRNDRVIYIKSFSKIFLPGIRIG
YVIAPKDLREQIQNCKINTDISTSSLMQRALDLYLIKGLWKEYIDYLYKIYVPKYEFTKNTIQDILKNKVELQNPGGGLH
FYIKIKENANINSMELFNECMKNKVLITPGVLFYKNPKDGLKYFRLGFSENSIEEIELGIKKINHILEKRLN
>Mature_472_residues
MEKYILIFQENSIPKYVQLYKYIKNMIDKNKIKDNEKLPSIRKLSNLLAINTVTVINAYKKLENDGYAIQKIGSGTYAKK
KEISRNLRKEYSDSIKSIGKEEFKAYIDFIGESACSDLFPVESFKSILNEVLDRDGKDALVYQETLGFEGLRKHISEVFW
NNKIEKNHILIVSGAQQGIDIISKSIINVNDNVLIEKPTYSGALSVFKWRRANIYEVPMEEDGVNIKELEKIVKKNNIKC
FYTMSYFQNPTGISCSLEKKKAILNLATIYDFYIIEDDYLSELIYDKSIQYITFKSLDRNDRVIYIKSFSKIFLPGIRIG
YVIAPKDLREQIQNCKINTDISTSSLMQRALDLYLIKGLWKEYIDYLYKIYVPKYEFTKNTIQDILKNKVELQNPGGGLH
FYIKIKENANINSMELFNECMKNKVLITPGVLFYKNPKDGLKYFRLGFSENSIEEIELGIKKINHILEKRLN

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=324, Percent_Identity=32.7160493827161, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI33469970, Length=324, Percent_Identity=32.7160493827161, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1787710, Length=471, Percent_Identity=25.0530785562633, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1790797, Length=439, Percent_Identity=22.3234624145786, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321236, Length=361, Percent_Identity=23.2686980609418, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6321929, Length=250, Percent_Identity=26.4, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356535, Length=376, Percent_Identity=26.3297872340426, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54927; Mature: 54927

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKYILIFQENSIPKYVQLYKYIKNMIDKNKIKDNEKLPSIRKLSNLLAINTVTVINAYK
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KLENDGYAIQKIGSGTYAKKKEISRNLRKEYSDSIKSIGKEEFKAYIDFIGESACSDLFP
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCC
VESFKSILNEVLDRDGKDALVYQETLGFEGLRKHISEVFWNNKIEKNHILIVSGAQQGID
HHHHHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHH
IISKSIINVNDNVLIEKPTYSGALSVFKWRRANIYEVPMEEDGVNIKELEKIVKKNNIKC
HHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCCEE
FYTMSYFQNPTGISCSLEKKKAILNLATIYDFYIIEDDYLSELIYDKSIQYITFKSLDRN
EEEEHHCCCCCCCEEEEHHHHHHHHHHHHHEEEEECHHHHHHHHHCCCCCEEEEECCCCC
DRVIYIKSFSKIFLPGIRIGYVIAPKDLREQIQNCKINTDISTSSLMQRALDLYLIKGLW
CCEEEEECCCHHHCCCCEEEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
KEYIDYLYKIYVPKYEFTKNTIQDILKNKVELQNPGGGLHFYIKIKENANINSMELFNEC
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEECCCCCCEEEEEEEECCCCCCHHHHHHHH
MKNKVLITPGVLFYKNPKDGLKYFRLGFSENSIEEIELGIKKINHILEKRLN
HHCCEEECCCEEEECCCHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKYILIFQENSIPKYVQLYKYIKNMIDKNKIKDNEKLPSIRKLSNLLAINTVTVINAYK
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KLENDGYAIQKIGSGTYAKKKEISRNLRKEYSDSIKSIGKEEFKAYIDFIGESACSDLFP
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCC
VESFKSILNEVLDRDGKDALVYQETLGFEGLRKHISEVFWNNKIEKNHILIVSGAQQGID
HHHHHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHH
IISKSIINVNDNVLIEKPTYSGALSVFKWRRANIYEVPMEEDGVNIKELEKIVKKNNIKC
HHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCCEE
FYTMSYFQNPTGISCSLEKKKAILNLATIYDFYIIEDDYLSELIYDKSIQYITFKSLDRN
EEEEHHCCCCCCCEEEEHHHHHHHHHHHHHEEEEECHHHHHHHHHCCCCCEEEEECCCCC
DRVIYIKSFSKIFLPGIRIGYVIAPKDLREQIQNCKINTDISTSSLMQRALDLYLIKGLW
CCEEEEECCCHHHCCCCEEEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
KEYIDYLYKIYVPKYEFTKNTIQDILKNKVELQNPGGGLHFYIKIKENANINSMELFNEC
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEECCCCCCEEEEEEEECCCCCCHHHHHHHH
MKNKVLITPGVLFYKNPKDGLKYFRLGFSENSIEEIELGIKKINHILEKRLN
HHCCEEECCCEEEECCCHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]