Click here to switch to the map view.

The map label for this gene is yvyE [H]

Identifier: 226950503

GI number: 226950503

Start: 3499915

End: 3500565

Strand: Reverse

Name: yvyE [H]

Synonym: CLM_3479

Alternate gene names: 226950503

Gene position: 3500565-3499915 (Counterclockwise)

Preceding gene: 226950504

Following gene: 226950502

Centisome position: 84.24

GC content: 30.57

Gene sequence:

>651_bases
ATGTCATATTTTACTATAAAAAACTTTGGAAAAGATGAATTTGAAGAAAAAAAGTCCACTTTTATAGGAAGAGCAAAAAG
AGTTTATACAGAAGAAGAAGCTAAGGATTTTATAAATAAAGTTAAAGGGGAAGAAAAGGAAGCAAGACATAATGTCTATG
CATATGTTATTGGAGAAAACATGGGAATACAGAGATATAGTGATGATGGCGAGCCACAAGGAACAGGTGGTATACCAGTA
TTAGATGTTATAAAAAAGAATGAAGTTACAGATATAGCTATAGTAGTTACAAGATATTTTGGGGGAATACTTCTAGGTAA
AGGTGGACTAGTAAGGGCCTATTCAAAAGGAGCCGCTGTAGCCATAAAGGATGCAGGTATAGTCGAAAAAGTTAAAGGCA
AATCTCTCACTTTCATAGTAGAATATGATGCTTTAGGCAAAATACAGTATTTGTTTGAACAAAATCTTTGGCATATAGAA
AATATAGAATATACAGAAAAAGTTAGTTTGGCTATATTTTGTGAAGTAAATATTATATCTACAATAGAAAAGAAAGTTCT
AGAGATAACCAACGGAAATTGTAAAATAATTAAAGGAGATGAAAATTTCTACTTTAAAATGGATAATAGGCTATTTGAAG
ATGAGCAATAA

Upstream 100 bases:

>100_bases
TATATATATAAAAAATAAAACTGATAAAGATTATATATTAAAAGCAGTAGATGAATATTTACAAGAAATAGATGACCCTA
TATAGAAAAGAGGTATGCTG

Downstream 100 bases:

>100_bases
ATTTGAATTTTTGACTTTCTCTATGATATAATAACTTAGTGAATTTGCATTTAAATATTAGTATTTTCAATTATAAATAT
ACTAATAAAAATAGTTTTAA

Product: hypothetical protein

Products: dihydrofolate; dTMP

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSYFTIKNFGKDEFEEKKSTFIGRAKRVYTEEEAKDFINKVKGEEKEARHNVYAYVIGENMGIQRYSDDGEPQGTGGIPV
LDVIKKNEVTDIAIVVTRYFGGILLGKGGLVRAYSKGAAVAIKDAGIVEKVKGKSLTFIVEYDALGKIQYLFEQNLWHIE
NIEYTEKVSLAIFCEVNIISTIEKKVLEITNGNCKIIKGDENFYFKMDNRLFEDEQ

Sequences:

>Translated_216_residues
MSYFTIKNFGKDEFEEKKSTFIGRAKRVYTEEEAKDFINKVKGEEKEARHNVYAYVIGENMGIQRYSDDGEPQGTGGIPV
LDVIKKNEVTDIAIVVTRYFGGILLGKGGLVRAYSKGAAVAIKDAGIVEKVKGKSLTFIVEYDALGKIQYLFEQNLWHIE
NIEYTEKVSLAIFCEVNIISTIEKKVLEITNGNCKIIKGDENFYFKMDNRLFEDEQ
>Mature_215_residues
SYFTIKNFGKDEFEEKKSTFIGRAKRVYTEEEAKDFINKVKGEEKEARHNVYAYVIGENMGIQRYSDDGEPQGTGGIPVL
DVIKKNEVTDIAIVVTRYFGGILLGKGGLVRAYSKGAAVAIKDAGIVEKVKGKSLTFIVEYDALGKIQYLFEQNLWHIEN
IEYTEKVSLAIFCEVNIISTIEKKVLEITNGNCKIIKGDENFYFKMDNRLFEDEQ

Specific function: Unknown

COG id: COG1739

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IMPACT family [H]

Homologues:

Organism=Escherichia coli, GI87082338, Length=189, Percent_Identity=34.9206349206349, Blast_Score=80, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR020568
- InterPro:   IPR000640
- InterPro:   IPR015796
- InterPro:   IPR015269
- InterPro:   IPR020569
- InterPro:   IPR001498 [H]

Pfam domain/function: PF09186 DUF1949; PF01205 UPF0029 [H]

EC number: 2.1.1.45

Molecular weight: Translated: 24525; Mature: 24394

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00910 UPF0029

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYFTIKNFGKDEFEEKKSTFIGRAKRVYTEEEAKDFINKVKGEEKEARHNVYAYVIGEN
CCEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECC
MGIQRYSDDGEPQGTGGIPVLDVIKKNEVTDIAIVVTRYFGGILLGKGGLVRAYSKGAAV
CCCEEECCCCCCCCCCCCCCEEEECCCCCCHHHEEEEHHHCEEEECCCCEEEEECCCCEE
AIKDAGIVEKVKGKSLTFIVEYDALGKIQYLFEQNLWHIENIEYTEKVSLAIFCEVNIIS
EEECCCCHHHCCCCEEEEEEEECCCCHHHEEHHCCCEEECCCCCCCEEEEEEEEEEHHHH
TIEKKVLEITNGNCKIIKGDENFYFKMDNRLFEDEQ
HHHHHHHEEECCCEEEEECCCCEEEEECCEECCCCC
>Mature Secondary Structure 
SYFTIKNFGKDEFEEKKSTFIGRAKRVYTEEEAKDFINKVKGEEKEARHNVYAYVIGEN
CEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECC
MGIQRYSDDGEPQGTGGIPVLDVIKKNEVTDIAIVVTRYFGGILLGKGGLVRAYSKGAAV
CCCEEECCCCCCCCCCCCCCEEEECCCCCCHHHEEEEHHHCEEEECCCCEEEEECCCCEE
AIKDAGIVEKVKGKSLTFIVEYDALGKIQYLFEQNLWHIENIEYTEKVSLAIFCEVNIIS
EEECCCCHHHCCCCEEEEEEEECCCCHHHEEHHCCCEEECCCCCCCEEEEEEEEEEHHHH
TIEKKVLEITNGNCKIIKGDENFYFKMDNRLFEDEQ
HHHHHHHEEECCCEEEEECCCCEEEEECCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5,10-methylenetetrahydrofolate; dUMP

Specific reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 3141378; 8313894 [H]