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The map label for this gene is dtd [H]

Identifier: 226950487

GI number: 226950487

Start: 3484529

End: 3484978

Strand: Reverse

Name: dtd [H]

Synonym: CLM_3463

Alternate gene names: 226950487

Gene position: 3484978-3484529 (Counterclockwise)

Preceding gene: 226950488

Following gene: 226950486

Centisome position: 83.87

GC content: 27.11

Gene sequence:

>450_bases
TTGAGAGCGGTAGTTCAGAGAGTTATATCTTCTAAAGTAGAAGTGGATGGAAAGGTTATAGGAAGTATAGGAAAAGGATT
AAATGTTCTTTTAGGAATATCAAAAGAAGATACAGAAGAGGATATAAAATATTTAAAAGAAAAAATAATAAATTTAAGAA
TATTTGAAGATGAAAATGAAAAATTAAATAAATCCTTATTGGATATAGGTGGAGATATAATAATTGTTTCTCAATTTACT
TTATATGGAGATTGTAGAAAAGGAAGAAGACCAAGTTTCATAGAAGCCTTAGGAGGAGAAGAGGCTTATATACTATATAA
TAAGTTTGTAGAATCAATAAAAAAAGAAGTAAACAATGTAGCAACTGGAGAATTTGGAGCAGATATGAAAGTTTATATAG
AAAATGATGGGCCAGTTACAATACTTTTAGATAGTAAAAAGACATTTTAA

Upstream 100 bases:

>100_bases
AATGAAAGATATAAGAAAACTAAAGGGTGTATTAGAAGTATATAGGACTAAAAAATAAATACTATAAATATAAAAGATTA
CAAATAAAGGTGGGATATGT

Downstream 100 bases:

>100_bases
AAGTTTAGTTATATACTAAAAGAGAGTAGAAAATTTTAATTTTTAAAAGAGGTGTATTTAATGGATATAAAGACAATACC
TGTTGGTATATACAATGCGA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRAVVQRVISSKVEVDGKVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENEKLNKSLLDIGGDIIIVSQFT
LYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNVATGEFGADMKVYIENDGPVTILLDSKKTF

Sequences:

>Translated_149_residues
MRAVVQRVISSKVEVDGKVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENEKLNKSLLDIGGDIIIVSQFT
LYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNVATGEFGADMKVYIENDGPVTILLDSKKTF
>Mature_149_residues
MRAVVQRVISSKVEVDGKVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENEKLNKSLLDIGGDIIIVSQFT
LYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNVATGEFGADMKVYIENDGPVTILLDSKKTF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=48.3221476510067, Blast_Score=130, Evalue=6e-31,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=44.7552447552448, Blast_Score=130, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=45.6375838926174, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=43.2432432432432, Blast_Score=111, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=48.2993197278912, Blast_Score=137, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16648; Mature: 16648

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVQRVISSKVEVDGKVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENE
CHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHEEEEEECCCH
KLNKSLLDIGGDIIIVSQFTLYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNV
HHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHHHHC
ATGEFGADMKVYIENDGPVTILLDSKKTF
CCCCCCCCEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MRAVVQRVISSKVEVDGKVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENE
CHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHEEEEEECCCH
KLNKSLLDIGGDIIIVSQFTLYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNV
HHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHHHHC
ATGEFGADMKVYIENDGPVTILLDSKKTF
CCCCCCCCEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA