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The map label for this gene is obgE [H]

Identifier: 226950410

GI number: 226950410

Start: 3416509

End: 3417783

Strand: Reverse

Name: obgE [H]

Synonym: CLM_3381

Alternate gene names: 226950410

Gene position: 3417783-3416509 (Counterclockwise)

Preceding gene: 226950411

Following gene: 226950409

Centisome position: 82.25

GC content: 31.92

Gene sequence:

>1275_bases
TTGTTTATAGATACAGCCAAAATATTTGTAAAATCAGGAAAAGGAGGAGATGGATCCATCTCTTTTAGAAGAGAAAAATA
TATAGCTTTTGGAGGACCAGATGGTGGAGATGGCGGTAAAGGCGGTAATGTAGTACTAGTAGTAGATCCTAATATGACAA
CTCTATTAGATTTTACTTATAAAAGAAAATATAAAGCGGAACCAGGTGGAAATGGCGCAGGATCAAAATGTTTTGGTAAA
AACGGTAAAGATCTACATATAAAAGTACCTATGGGAACTATAGTTAAAGATGCAGAAACAGACAAAATAATGGCAGATTT
ATCAAAACCAGAGGACTCTTATGTGGTTGCTAAAGGTGGAAGAGGTGGTAAAGGTAATTGCAGATTTACAACACCTACAA
GACAGGCACCAGATTTTGCAGAACCAGGTATGCCAGAGGAAGAAAGATGGATTAAGCTTGAATTAAAACTTTTAGCAGAC
GTGGGCCTTATAGGATTTCCTAACGTGGGAAAATCTACTTTATTATCAGTCGTATCTAAAGCTAGACCTAAAATAGCTAA
CTATCATTTTACTACATTAAAACCTAATTTAGGCGTGGTAAGTATTGAAGGTGTAAATAATTTTGTAATTGCAGATATAC
CAGGAATAATTGAAGGTGCTTCAGAAGGAGTAGGATTAGGTTTAGATTTTTTAAGACATGTAGAGAGAACAAGAGTATTA
ATTCATGTAATAGATATATCTTCTGTAGAAGGAAGAGACCCTTATGATGATTTTTTAAAGATAAACGACGAACTAAAAAG
ATATAGTGTAAAACTTTATGATAGACCTCAAATAATAGCTGCTAATAAATCTGATATGTTATTTGATGAAGAAAAGTTTG
AAGAATTTAAAACAAAAGTAGAAAAACATGGTTATAATAAGGTGTTTAAGATATCAGCAGCTACAAAGCAAGGTGTAGAT
GATCTTATGAAAGAAGCTGCAAGACTTTTAAGTACTATACCTGTTACAGATCTAGAAATATCAGAAGAAGATAGATTTAT
AGAGGAAGAAAAGAGATTTACATACTCTATAAGAAAAGAAGATAACACTTATATTGTGGAAGGAAGTTTTGTAGATAGAC
TTTTGAATGCAGTTAATGTAAATGATCCAGATGATTTAAGATATTTCCATAAAGTACTTAAAAATAAAGGGGTAATGGAA
GAATTAATGGAAATGGGTATTGAAGATGGTGATGTTGTACGATTAAATGACTTTGAATTTGACTTTTTATTATAA

Upstream 100 bases:

>100_bases
TATAAAATTAACACAATTGACTATACATTTAAATTAGTATAGCTAAATTTTATAAGCAATATTATATATTAATTATCGAA
GTAAAGAGGAGTGAAAAACT

Downstream 100 bases:

>100_bases
TATATGACTTTAGGAGGAATACAATAATGATAACAACAAAACAGAGAAGTTATTTAAGATCTTTAGCTAATAAGATGGAT
GCTATATTTCAAATAGGTAA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MFIDTAKIFVKSGKGGDGSISFRREKYIAFGGPDGGDGGKGGNVVLVVDPNMTTLLDFTYKRKYKAEPGGNGAGSKCFGK
NGKDLHIKVPMGTIVKDAETDKIMADLSKPEDSYVVAKGGRGGKGNCRFTTPTRQAPDFAEPGMPEEERWIKLELKLLAD
VGLIGFPNVGKSTLLSVVSKARPKIANYHFTTLKPNLGVVSIEGVNNFVIADIPGIIEGASEGVGLGLDFLRHVERTRVL
IHVIDISSVEGRDPYDDFLKINDELKRYSVKLYDRPQIIAANKSDMLFDEEKFEEFKTKVEKHGYNKVFKISAATKQGVD
DLMKEAARLLSTIPVTDLEISEEDRFIEEEKRFTYSIRKEDNTYIVEGSFVDRLLNAVNVNDPDDLRYFHKVLKNKGVME
ELMEMGIEDGDVVRLNDFEFDFLL

Sequences:

>Translated_424_residues
MFIDTAKIFVKSGKGGDGSISFRREKYIAFGGPDGGDGGKGGNVVLVVDPNMTTLLDFTYKRKYKAEPGGNGAGSKCFGK
NGKDLHIKVPMGTIVKDAETDKIMADLSKPEDSYVVAKGGRGGKGNCRFTTPTRQAPDFAEPGMPEEERWIKLELKLLAD
VGLIGFPNVGKSTLLSVVSKARPKIANYHFTTLKPNLGVVSIEGVNNFVIADIPGIIEGASEGVGLGLDFLRHVERTRVL
IHVIDISSVEGRDPYDDFLKINDELKRYSVKLYDRPQIIAANKSDMLFDEEKFEEFKTKVEKHGYNKVFKISAATKQGVD
DLMKEAARLLSTIPVTDLEISEEDRFIEEEKRFTYSIRKEDNTYIVEGSFVDRLLNAVNVNDPDDLRYFHKVLKNKGVME
ELMEMGIEDGDVVRLNDFEFDFLL
>Mature_424_residues
MFIDTAKIFVKSGKGGDGSISFRREKYIAFGGPDGGDGGKGGNVVLVVDPNMTTLLDFTYKRKYKAEPGGNGAGSKCFGK
NGKDLHIKVPMGTIVKDAETDKIMADLSKPEDSYVVAKGGRGGKGNCRFTTPTRQAPDFAEPGMPEEERWIKLELKLLAD
VGLIGFPNVGKSTLLSVVSKARPKIANYHFTTLKPNLGVVSIEGVNNFVIADIPGIIEGASEGVGLGLDFLRHVERTRVL
IHVIDISSVEGRDPYDDFLKINDELKRYSVKLYDRPQIIAANKSDMLFDEEKFEEFKTKVEKHGYNKVFKISAATKQGVD
DLMKEAARLLSTIPVTDLEISEEDRFIEEEKRFTYSIRKEDNTYIVEGSFVDRLLNAVNVNDPDDLRYFHKVLKNKGVME
ELMEMGIEDGDVVRLNDFEFDFLL

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=322, Percent_Identity=42.2360248447205, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI111955139, Length=347, Percent_Identity=36.8876080691643, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI111955063, Length=246, Percent_Identity=32.9268292682927, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4557537, Length=89, Percent_Identity=42.6966292134831, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=34.6456692913386, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789574, Length=348, Percent_Identity=47.1264367816092, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1787454, Length=140, Percent_Identity=35, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790615, Length=172, Percent_Identity=29.0697674418605, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=37.962962962963, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=32.3624595469256, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=35.2517985611511, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=36.4406779661017, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=183, Percent_Identity=40.9836065573771, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321612, Length=94, Percent_Identity=39.3617021276596, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=128, Percent_Identity=33.59375, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20129375, Length=328, Percent_Identity=39.9390243902439, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24585318, Length=360, Percent_Identity=32.5, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=34.1085271317829, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=34.1085271317829, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=34.1085271317829, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356473, Length=89, Percent_Identity=42.6966292134831, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=35.4330708661417, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47216; Mature: 47216

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDTAKIFVKSGKGGDGSISFRREKYIAFGGPDGGDGGKGGNVVLVVDPNMTTLLDFTY
CEECCEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEHH
KRKYKAEPGGNGAGSKCFGKNGKDLHIKVPMGTIVKDAETDKIMADLSKPEDSYVVAKGG
HHEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHCCCCCHHHHHHHCCCCCCCEEEEECC
RGGKGNCRFTTPTRQAPDFAEPGMPEEERWIKLELKLLADVGLIGFPNVGKSTLLSVVSK
CCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
ARPKIANYHFTTLKPNLGVVSIEGVNNFVIADIPGIIEGASEGVGLGLDFLRHVERTRVL
CCCCCCCEEEEEECCCCCEEEECCCCCEEEECCCHHHCCCCCCCCCCHHHHHHHHHCEEE
IHVIDISSVEGRDPYDDFLKINDELKRYSVKLYDRPQIIAANKSDMLFDEEKFEEFKTKV
EEEEEECCCCCCCCHHHHHHHCCHHEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHH
EKHGYNKVFKISAATKQGVDDLMKEAARLLSTIPVTDLEISEEDRFIEEEKRFTYSIRKE
HHCCCCEEEEEECHHHCCHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHCCEEEEEEEC
DNTYIVEGSFVDRLLNAVNVNDPDDLRYFHKVLKNKGVMEELMEMGIEDGDVVRLNDFEF
CCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCE
DFLL
EEEC
>Mature Secondary Structure
MFIDTAKIFVKSGKGGDGSISFRREKYIAFGGPDGGDGGKGGNVVLVVDPNMTTLLDFTY
CEECCEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEHH
KRKYKAEPGGNGAGSKCFGKNGKDLHIKVPMGTIVKDAETDKIMADLSKPEDSYVVAKGG
HHEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHCCCCCHHHHHHHCCCCCCCEEEEECC
RGGKGNCRFTTPTRQAPDFAEPGMPEEERWIKLELKLLADVGLIGFPNVGKSTLLSVVSK
CCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
ARPKIANYHFTTLKPNLGVVSIEGVNNFVIADIPGIIEGASEGVGLGLDFLRHVERTRVL
CCCCCCCEEEEEECCCCCEEEECCCCCEEEECCCHHHCCCCCCCCCCHHHHHHHHHCEEE
IHVIDISSVEGRDPYDDFLKINDELKRYSVKLYDRPQIIAANKSDMLFDEEKFEEFKTKV
EEEEEECCCCCCCCHHHHHHHCCHHEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHH
EKHGYNKVFKISAATKQGVDDLMKEAARLLSTIPVTDLEISEEDRFIEEEKRFTYSIRKE
HHCCCCEEEEEECHHHCCHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHCCEEEEEEEC
DNTYIVEGSFVDRLLNAVNVNDPDDLRYFHKVLKNKGVMEELMEMGIEDGDVVRLNDFEF
CCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCE
DFLL
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA