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The map label for this gene is comEA [H]

Identifier: 226950402

GI number: 226950402

Start: 3409628

End: 3410236

Strand: Reverse

Name: comEA [H]

Synonym: CLM_3373

Alternate gene names: 226950402

Gene position: 3410236-3409628 (Counterclockwise)

Preceding gene: 226950404

Following gene: 226950401

Centisome position: 82.07

GC content: 27.75

Gene sequence:

>609_bases
ATGAAAGATAAAAAGAAAATAATAGGATCTATAATAATAGTTTTTATTTTAGCAGTCTTTACAGTAATAGGATATGTACT
GTCAAAACCAGAAAAAGCTAATATAAAGGAAGAAGAAATATTTGTAGAGAATGTTAAAAGTACAAAAAAGGAAAATGTAA
AATTAGAAAAAGAGATAACTGTTTATGTAAATGGAGAAGTTAAGAATCCAGGTGTATATAAGCTTAAGGATAACAGCAGA
GTTGAAGAGTTAATAAAAATTTCTGGTGGCTATACTAGTAATGCAGATACATGTAAGCTGAATTTAGCAAAAAAGCTTAA
AGATGAGGATTATATTTATATAGAAAAAAAGGGAGGAAATAATGGAGGTGCAGATAATAGTGAAGTATCAACTAATTCTG
TAATTGGTGCAGATGGAAAAATAGATTTAAATAGTGCGTCTAAGGAGGAATTAAAGAGTATACCAGGTATAGGAGATGTA
ACTGCACAAAAGATATTAGATTATAGAGAAAAACAAGGAACTTTTAAAAATTTTGAAGATTTAAAAGCTATAGGAAGGAT
AGGAGATAAGACTATAGAAAAAATAAAAGAAAAAGCTGAAATAAGGTAG

Upstream 100 bases:

>100_bases
GTCAATAATTAGAACAATTAAAGGATTATATCCTATTTAGACATACTATAATGTTTGACAAAGTGTAATATAAATAACCA
TACTATGGAGTGATAAGCAT

Downstream 100 bases:

>100_bases
TATTCTTTATATTTCTTTTAAATTTTTACAAAATAATATATAATGAGTATTGAATAATTTATTATTTTTAATGTAGTTTG
GTTTTTATAAAGAGAGGTGC

Product: putative comE operon protein 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKDKKKIIGSIIIVFILAVFTVIGYVLSKPEKANIKEEEIFVENVKSTKKENVKLEKEITVYVNGEVKNPGVYKLKDNSR
VEELIKISGGYTSNADTCKLNLAKKLKDEDYIYIEKKGGNNGGADNSEVSTNSVIGADGKIDLNSASKEELKSIPGIGDV
TAQKILDYREKQGTFKNFEDLKAIGRIGDKTIEKIKEKAEIR

Sequences:

>Translated_202_residues
MKDKKKIIGSIIIVFILAVFTVIGYVLSKPEKANIKEEEIFVENVKSTKKENVKLEKEITVYVNGEVKNPGVYKLKDNSR
VEELIKISGGYTSNADTCKLNLAKKLKDEDYIYIEKKGGNNGGADNSEVSTNSVIGADGKIDLNSASKEELKSIPGIGDV
TAQKILDYREKQGTFKNFEDLKAIGRIGDKTIEKIKEKAEIR
>Mature_202_residues
MKDKKKIIGSIIIVFILAVFTVIGYVLSKPEKANIKEEEIFVENVKSTKKENVKLEKEITVYVNGEVKNPGVYKLKDNSR
VEELIKISGGYTSNADTCKLNLAKKLKDEDYIYIEKKGGNNGGADNSEVSTNSVIGADGKIDLNSASKEELKSIPGIGDV
TAQKILDYREKQGTFKNFEDLKAIGRIGDKTIEKIKEKAEIR

Specific function: Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect [H]

COG id: COG1555

COG function: function code L; DNA uptake protein and related DNA-binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HhH domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004787
- InterPro:   IPR004509
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR019554 [H]

Pfam domain/function: PF00633 HHH; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 22419; Mature: 22419

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKKKIIGSIIIVFILAVFTVIGYVLSKPEKANIKEEEIFVENVKSTKKENVKLEKEIT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEE
VYVNGEVKNPGVYKLKDNSRVEELIKISGGYTSNADTCKLNLAKKLKDEDYIYIEKKGGN
EEEECEECCCCEEEECCCHHHHHHHHHCCCCCCCCCEEEEHHHHHCCCCCEEEEECCCCC
NGGADNSEVSTNSVIGADGKIDLNSASKEELKSIPGIGDVTAQKILDYREKQGTFKNFED
CCCCCCCCCCCCCEECCCCEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHH
LKAIGRIGDKTIEKIKEKAEIR
HHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDKKKIIGSIIIVFILAVFTVIGYVLSKPEKANIKEEEIFVENVKSTKKENVKLEKEIT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEE
VYVNGEVKNPGVYKLKDNSRVEELIKISGGYTSNADTCKLNLAKKLKDEDYIYIEKKGGN
EEEECEECCCCEEEECCCHHHHHHHHHCCCCCCCCCEEEEHHHHHCCCCCEEEEECCCCC
NGGADNSEVSTNSVIGADGKIDLNSASKEELKSIPGIGDVTAQKILDYREKQGTFKNFED
CCCCCCCCCCCCCEECCCCEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHH
LKAIGRIGDKTIEKIKEKAEIR
HHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377; 7768800 [H]