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The map label for this gene is hrcA [H]

Identifier: 226950387

GI number: 226950387

Start: 3388166

End: 3389197

Strand: Reverse

Name: hrcA [H]

Synonym: CLM_3356

Alternate gene names: 226950387

Gene position: 3389197-3388166 (Counterclockwise)

Preceding gene: 226950388

Following gene: 226950386

Centisome position: 81.56

GC content: 27.81

Gene sequence:

>1032_bases
ATGGATGAGAGAAAAATCAGGATACTTCAAGCTATAATAAAAGATTATATTAATAGTGGAGAACCCGTTGGATCAAGAAC
TATTGCTAAAAAATATGATTTAGGAGTAAGTTCGGCAACTATAAGAAATGAGATGGCAGACCTAGAAGATATGGGATATT
TAGAACAGATTCATAGTTCATCTGGAAGAAAACCATCAGATAAAGGCTATAGACTATATGTAGATAAACTTATGACATTA
ACAGCTCTAACAGAGCGGGAAAAAATGCTCATAAAAGATCAAGCTATAGATTCAGCCTTATATGAAATAGATAAGACCAT
AAGACATTCTATAAGTATATTATCTGAAATCACTAAATTAACTTGTTTAGTGAAAACTCCTTCTATGATAAAAAGTAGAT
TGAGATCAATACAAATAATTAAGGTTGATAAGTATAATTTATTATTGATTGTTATAACAGATAATGCCATGATAAAAAAT
ACGCTATTAAGAGTAACAAAAGAAATAGATGAAGGCTCCTTAATAAAAATAAATAATTTATTAAACCAAAAATTAAAAGG
ACTAAATCTAAGAGAAGTAAATTTAGAATTATTAAACGAATTAAAAAAAGAGATGACAGGATATGGTGATATATTAAAAA
ATATTCTATCCTCTATATATGAAGCACTTACGGATATAGAGGATGCAGAAATATATATGGAAGGAACCACAAATATATTC
AATTATCCTGAATACAATGATGTAGATAGAGCTAAAGAATTTCTATCTATGCTAAATGATAGAGAAAAGGTAGAAGAATT
ATTATATGTGGATTCTGATATTGCTGTAAAAATAGGAAAAGAAAATTTTGTAGAAGATGCAAAACAATGTAGTGTTATTT
CAGCAGTATATAGTATAGGAAAGACACCCATAGGGACTATAGGAGTTATAGGACCTACAAGAATACCTTATGAAAAAATA
ATATCAGCTGTGGCTACAATAGTTAAGGAAATAAATGATACCTTAACTAATGACAAAAATATTCATAAATAA

Upstream 100 bases:

>100_bases
AATAGATAGGTTGACAAATAATTTGTACAATGTTAGATTTTAATCATAGTAATTAGCACTCGTTGCTAGTGAGTGCTAAT
AAAAGAGGTGTCAATATGAT

Downstream 100 bases:

>100_bases
CAAGCGGATAGAATGGAGGTATATAATTGGAAAAAGAATGCAAGGATGCTAAACATATTAACATGGAAGAGGATTGCTGC
TGCTCTAATAAAGAAAGTGA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MDERKIRILQAIIKDYINSGEPVGSRTIAKKYDLGVSSATIRNEMADLEDMGYLEQIHSSSGRKPSDKGYRLYVDKLMTL
TALTEREKMLIKDQAIDSALYEIDKTIRHSISILSEITKLTCLVKTPSMIKSRLRSIQIIKVDKYNLLLIVITDNAMIKN
TLLRVTKEIDEGSLIKINNLLNQKLKGLNLREVNLELLNELKKEMTGYGDILKNILSSIYEALTDIEDAEIYMEGTTNIF
NYPEYNDVDRAKEFLSMLNDREKVEELLYVDSDIAVKIGKENFVEDAKQCSVISAVYSIGKTPIGTIGVIGPTRIPYEKI
ISAVATIVKEINDTLTNDKNIHK

Sequences:

>Translated_343_residues
MDERKIRILQAIIKDYINSGEPVGSRTIAKKYDLGVSSATIRNEMADLEDMGYLEQIHSSSGRKPSDKGYRLYVDKLMTL
TALTEREKMLIKDQAIDSALYEIDKTIRHSISILSEITKLTCLVKTPSMIKSRLRSIQIIKVDKYNLLLIVITDNAMIKN
TLLRVTKEIDEGSLIKINNLLNQKLKGLNLREVNLELLNELKKEMTGYGDILKNILSSIYEALTDIEDAEIYMEGTTNIF
NYPEYNDVDRAKEFLSMLNDREKVEELLYVDSDIAVKIGKENFVEDAKQCSVISAVYSIGKTPIGTIGVIGPTRIPYEKI
ISAVATIVKEINDTLTNDKNIHK
>Mature_343_residues
MDERKIRILQAIIKDYINSGEPVGSRTIAKKYDLGVSSATIRNEMADLEDMGYLEQIHSSSGRKPSDKGYRLYVDKLMTL
TALTEREKMLIKDQAIDSALYEIDKTIRHSISILSEITKLTCLVKTPSMIKSRLRSIQIIKVDKYNLLLIVITDNAMIKN
TLLRVTKEIDEGSLIKINNLLNQKLKGLNLREVNLELLNELKKEMTGYGDILKNILSSIYEALTDIEDAEIYMEGTTNIF
NYPEYNDVDRAKEFLSMLNDREKVEELLYVDSDIAVKIGKENFVEDAKQCSVISAVYSIGKTPIGTIGVIGPTRIPYEKI
ISAVATIVKEINDTLTNDKNIHK

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38833; Mature: 38833

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERKIRILQAIIKDYINSGEPVGSRTIAKKYDLGVSSATIRNEMADLEDMGYLEQIHSS
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SGRKPSDKGYRLYVDKLMTLTALTEREKMLIKDQAIDSALYEIDKTIRHSISILSEITKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TCLVKTPSMIKSRLRSIQIIKVDKYNLLLIVITDNAMIKNTLLRVTKEIDEGSLIKINNL
HHHHCCHHHHHHHHHCEEEEEECCCEEEEEEEECCHHHHHHHHHHHHHCCCCCEEEHHHH
LNQKLKGLNLREVNLELLNELKKEMTGYGDILKNILSSIYEALTDIEDAEIYMEGTTNIF
HHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
NYPEYNDVDRAKEFLSMLNDREKVEELLYVDSDIAVKIGKENFVEDAKQCSVISAVYSIG
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHC
KTPIGTIGVIGPTRIPYEKIISAVATIVKEINDTLTNDKNIHK
CCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDERKIRILQAIIKDYINSGEPVGSRTIAKKYDLGVSSATIRNEMADLEDMGYLEQIHSS
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SGRKPSDKGYRLYVDKLMTLTALTEREKMLIKDQAIDSALYEIDKTIRHSISILSEITKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TCLVKTPSMIKSRLRSIQIIKVDKYNLLLIVITDNAMIKNTLLRVTKEIDEGSLIKINNL
HHHHCCHHHHHHHHHCEEEEEECCCEEEEEEEECCHHHHHHHHHHHHHCCCCCEEEHHHH
LNQKLKGLNLREVNLELLNELKKEMTGYGDILKNILSSIYEALTDIEDAEIYMEGTTNIF
HHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
NYPEYNDVDRAKEFLSMLNDREKVEELLYVDSDIAVKIGKENFVEDAKQCSVISAVYSIG
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHC
KTPIGTIGVIGPTRIPYEKIISAVATIVKEINDTLTNDKNIHK
CCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1577695; 11466286 [H]