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The map label for this gene is cdd [H]

Identifier: 226950372

GI number: 226950372

Start: 3374422

End: 3374820

Strand: Reverse

Name: cdd [H]

Synonym: CLM_3341

Alternate gene names: 226950372

Gene position: 3374820-3374422 (Counterclockwise)

Preceding gene: 226950373

Following gene: 226950371

Centisome position: 81.22

GC content: 30.33

Gene sequence:

>399_bases
ATGAAATATGACGAAATTATAAAGAAAGCAATAGAAGCCAGAGAAAATGCTTATGTTCCTTACTCAAAATTTAGAGTAGG
AGCTGCTTTATTAACAGAAGATAACGCAATATATACAGGATGTAATATAGAAAACGCTTCCTATGGTGCTACAAATTGTG
CAGAAAGAACAGCTATATTTAAAGCTATATCAGAAGGGCATAAGAAAATAAAAGCCATCGCAGTTGTAGGGAGTCTTGAA
GAATATACTTATCCTTGTGGCATATGTAGGCAGGTTATAAGTGAATTTGCAGATGGAAATATAGACATAATAATAGTGAA
AGATAAAAATAATTATGAAATAAAGAAACTAGATGAAATTTTACCAGGAGCTTTTACTAAAAAAGATCTAATAAAATAG

Upstream 100 bases:

>100_bases
ATAAAATATTTGGATAGTTGAAATAATGTAAAATAATGCTATAATTTATTTGCAAAATAATTTGTAGGGTAAATAGTTTA
TCCAAACAGGAGGATTTATA

Downstream 100 bases:

>100_bases
ACGAGGAGATAAAATATGTTTAAATCAGGATTTGTAACCATAGTAGGAAGACCTAATGTAGGAAAATCAACGTTATTAAA
TGCCATAATGAAAGAGAAAC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MKYDEIIKKAIEARENAYVPYSKFRVGAALLTEDNAIYTGCNIENASYGATNCAERTAIFKAISEGHKKIKAIAVVGSLE
EYTYPCGICRQVISEFADGNIDIIIVKDKNNYEIKKLDEILPGAFTKKDLIK

Sequences:

>Translated_132_residues
MKYDEIIKKAIEARENAYVPYSKFRVGAALLTEDNAIYTGCNIENASYGATNCAERTAIFKAISEGHKKIKAIAVVGSLE
EYTYPCGICRQVISEFADGNIDIIIVKDKNNYEIKKLDEILPGAFTKKDLIK
>Mature_132_residues
MKYDEIIKKAIEARENAYVPYSKFRVGAALLTEDNAIYTGCNIENASYGATNCAERTAIFKAISEGHKKIKAIAVVGSLE
EYTYPCGICRQVISEFADGNIDIIIVKDKNNYEIKKLDEILPGAFTKKDLIK

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=130, Percent_Identity=45.3846153846154, Blast_Score=121, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17540514, Length=126, Percent_Identity=49.2063492063492, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17551074, Length=127, Percent_Identity=49.6062992125984, Blast_Score=115, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6323274, Length=132, Percent_Identity=36.3636363636364, Blast_Score=99, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24582741, Length=128, Percent_Identity=47.65625, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24582744, Length=104, Percent_Identity=51.9230769230769, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI19920920, Length=106, Percent_Identity=48.1132075471698, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14703; Mature: 14703

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYDEIIKKAIEARENAYVPYSKFRVGAALLTEDNAIYTGCNIENASYGATNCAERTAIF
CCHHHHHHHHHHHHCCCCCCHHHHHHCCCEEECCCEEEECCCCCCCCCCCCHHHHHHHHH
KAISEGHKKIKAIAVVGSLEEYTYPCGICRQVISEFADGNIDIIIVKDKNNYEIKKLDEI
HHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
LPGAFTKKDLIK
CCCCCCHHHCCC
>Mature Secondary Structure
MKYDEIIKKAIEARENAYVPYSKFRVGAALLTEDNAIYTGCNIENASYGATNCAERTAIF
CCHHHHHHHHHHHHCCCCCCHHHHHHCCCEEECCCEEEECCCCCCCCCCCCHHHHHHHHH
KAISEGHKKIKAIAVVGSLEEYTYPCGICRQVISEFADGNIDIIIVKDKNNYEIKKLDEI
HHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
LPGAFTKKDLIK
CCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]