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The map label for this gene is era [H]

Identifier: 226950371

GI number: 226950371

Start: 3373516

End: 3374406

Strand: Reverse

Name: era [H]

Synonym: CLM_3340

Alternate gene names: 226950371

Gene position: 3374406-3373516 (Counterclockwise)

Preceding gene: 226950372

Following gene: 226950370

Centisome position: 81.21

GC content: 29.29

Gene sequence:

>891_bases
ATGTTTAAATCAGGATTTGTAACCATAGTAGGAAGACCTAATGTAGGAAAATCAACGTTATTAAATGCCATAATGAAAGA
GAAACTTTCTATAGTTTCATGCAGACCCCAGACTACAAGAAACAATATACAAACAATATTAACAGAAGATAATTATCAAC
TTGTATTTGTTGATACGCCAGGAATACATAAGCCTAAGCATAAGTTAGGAGAGTATATGGTGAAATCAGCATCAGATGCT
ATGAAGGATGTGGATTTAGTACTTTTTTTAATAAATCCAGATGAAAAACCTGGCAGGGGAGATTTGTTTATAATAGAACA
ATTAAAAGAAGTAAAAGTACCAGTATTTTTAGTTTTAAATAAAATAGATGAAAATCCACAAGAAAAAGTAGCAGAAACTT
TAAAAACATATTCAGAACTTATGGAGTTTCAAGAAATAATACCTATATCTGCTCTGAAAGGAAAAAATGTTGATTTACTT
AAAGAATTAATGTTTAAATATATACCAGAGGGTCCACAATACTATCCAGAAGATATGATAATAGATCAAAATGAGAGGTT
TATAGTGGCAGAGATAGTAAGGGAAAAAGCTTTAAGACTTTTATCAGAAGAAGTGCCTCATGGTATAGCTGTAGAAATAC
TTCAAATGAAGAAAAATGAAAAAGGCACTTATCACATAGAGGGTAATATATTATGTGAAAAGAATTCTCACAAACCTATA
ATTATAGGTAAAGGTGGCAGTAAATTAAAGAAAATATCTCAATATGCAAGACAGGATATAGAAGCTTTTCTTCAAAGCAA
AGTATATATAAGACTTTGGGTTAAAGTAAAAGAAGAGTGGAGAGATAATCAAAGTTTGTTAAAAGAATTAGGTTATAAAA
AAATGAAATAA

Upstream 100 bases:

>100_bases
AGTGAAAGATAAAAATAATTATGAAATAAAGAAACTAGATGAAATTTTACCAGGAGCTTTTACTAAAAAAGATCTAATAA
AATAGACGAGGAGATAAAAT

Downstream 100 bases:

>100_bases
ATAATATAGGGAGTTGATTTTCTGTCACTATATAAAACTAGAGCTGTAGTAATAAAAACTCAAGAATTTAAAGAAGCAGA
TAAATTAGTTTGGTTATATA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MFKSGFVTIVGRPNVGKSTLLNAIMKEKLSIVSCRPQTTRNNIQTILTEDNYQLVFVDTPGIHKPKHKLGEYMVKSASDA
MKDVDLVLFLINPDEKPGRGDLFIIEQLKEVKVPVFLVLNKIDENPQEKVAETLKTYSELMEFQEIIPISALKGKNVDLL
KELMFKYIPEGPQYYPEDMIIDQNERFIVAEIVREKALRLLSEEVPHGIAVEILQMKKNEKGTYHIEGNILCEKNSHKPI
IIGKGGSKLKKISQYARQDIEAFLQSKVYIRLWVKVKEEWRDNQSLLKELGYKKMK

Sequences:

>Translated_296_residues
MFKSGFVTIVGRPNVGKSTLLNAIMKEKLSIVSCRPQTTRNNIQTILTEDNYQLVFVDTPGIHKPKHKLGEYMVKSASDA
MKDVDLVLFLINPDEKPGRGDLFIIEQLKEVKVPVFLVLNKIDENPQEKVAETLKTYSELMEFQEIIPISALKGKNVDLL
KELMFKYIPEGPQYYPEDMIIDQNERFIVAEIVREKALRLLSEEVPHGIAVEILQMKKNEKGTYHIEGNILCEKNSHKPI
IIGKGGSKLKKISQYARQDIEAFLQSKVYIRLWVKVKEEWRDNQSLLKELGYKKMK
>Mature_296_residues
MFKSGFVTIVGRPNVGKSTLLNAIMKEKLSIVSCRPQTTRNNIQTILTEDNYQLVFVDTPGIHKPKHKLGEYMVKSASDA
MKDVDLVLFLINPDEKPGRGDLFIIEQLKEVKVPVFLVLNKIDENPQEKVAETLKTYSELMEFQEIIPISALKGKNVDLL
KELMFKYIPEGPQYYPEDMIIDQNERFIVAEIVREKALRLLSEEVPHGIAVEILQMKKNEKGTYHIEGNILCEKNSHKPI
IIGKGGSKLKKISQYARQDIEAFLQSKVYIRLWVKVKEEWRDNQSLLKELGYKKMK

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=322, Percent_Identity=27.639751552795, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1788919, Length=296, Percent_Identity=43.2432432432432, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI87082120, Length=162, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34075; Mature: 34075

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSGFVTIVGRPNVGKSTLLNAIMKEKLSIVSCRPQTTRNNIQTILTEDNYQLVFVDTP
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCCEEEEEEECC
GIHKPKHKLGEYMVKSASDAMKDVDLVLFLINPDEKPGRGDLFIIEQLKEVKVPVFLVLN
CCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCEEHEEHHHHCCCCHHEEEE
KIDENPQEKVAETLKTYSELMEFQEIIPISALKGKNVDLLKELMFKYIPEGPQYYPEDMI
HHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEE
IDQNERFIVAEIVREKALRLLSEEVPHGIAVEILQMKKNEKGTYHIEGNILCEKNSHKPI
ECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECEEEEECCCCCCE
IIGKGGSKLKKISQYARQDIEAFLQSKVYIRLWVKVKEEWRDNQSLLKELGYKKMK
EEECCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MFKSGFVTIVGRPNVGKSTLLNAIMKEKLSIVSCRPQTTRNNIQTILTEDNYQLVFVDTP
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCCEEEEEEECC
GIHKPKHKLGEYMVKSASDAMKDVDLVLFLINPDEKPGRGDLFIIEQLKEVKVPVFLVLN
CCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCEEHEEHHHHCCCCHHEEEE
KIDENPQEKVAETLKTYSELMEFQEIIPISALKGKNVDLLKELMFKYIPEGPQYYPEDMI
HHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEE
IDQNERFIVAEIVREKALRLLSEEVPHGIAVEILQMKKNEKGTYHIEGNILCEKNSHKPI
ECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECEEEEECCCCCCE
IIGKGGSKLKKISQYARQDIEAFLQSKVYIRLWVKVKEEWRDNQSLLKELGYKKMK
EEECCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA