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The map label for this gene is yeiT [H]

Identifier: 226950229

GI number: 226950229

Start: 3201179

End: 3202495

Strand: Reverse

Name: yeiT [H]

Synonym: CLM_3183

Alternate gene names: 226950229

Gene position: 3202495-3201179 (Counterclockwise)

Preceding gene: 226950230

Following gene: 226950228

Centisome position: 77.07

GC content: 33.56

Gene sequence:

>1317_bases
TTGGAAAATAAATTAACTTATATGAAAGAAAGAGAAGAAGTTTTTACACCTCTTCTAGCTATTGAAGAAGCATCAAGATG
TTTGCTATGTCATGATGCACCCTGTACAAAGGCGTGTCCAGCAGGTACAAATCCCGGAAAATTCATACGTTCATTACGTT
TTAGAAATTTTAATGGGGCCGTAGCTACAATTCGTGAAAATAATATATTAGGAGGGGTCTGTGCAAGAGTCTGTCCTACA
GATAAATATTGTGAAGGAGCCTGTAGTAGGTGTGGTATAGATAAGCCTATTCAAATAGGGAGACTTCAACGCTATTTAGC
AGATTATGAACAATTAACAGGAATAAAAATTTTAGAAGCTGTACAAGCTACAAAAGAAAAAGTAGCTATTATAGGTTCAG
GTCCAAGTGGACTTGCAGCGGCAGCTCAATTAGCTTTAGAAGGATATAAAGTCACTGTATTTGAAGTTAAAAATCAATTA
GGTGGATGGTTAACTTATGGAATACCAGAAGATAGGCTTCCACAAAAAGTTGTTGAAAATGAAATTGGATACATAAAGAA
TTTAGGTGTCCATTTTAGAACTAACTGTAAAGTTGGAAGAGATGTTAGTATAGATGATCTTAGAGAAGAAGGTTTTAAAG
CATTTTTAGTAGCAGTAGGCATGCAAAAGAGTAAAGACACAGAAGTAAAAGGCAATAATTTAGAAGGAGTTGTTGCTGGA
ACAAATTTTTTAGCAGAAGCTAAAACTTCTAAGGGAAAAGTTAAAGTTGGCAGCAAAGTTATAGTTATAGGTGGAGGAGA
TGTTGCTATGGATTGTGCTGTAACTGCTAAATTATTAGGATCAGAAGATGTCAAAATAGTTTATAGAAGAACTATAGAAA
GAATGCCAGCAGATAGAAAGGAAATAGCTTATACCCAAGATTTAAATATACCGATATTTACAGGATTAAAGCCAGCTGAA
ATAGTTGGACAATCTGGAAAAGTGGCCAGATTTAAAGCTACAGGAATGTTTGATGATTCAGAATTAAATCTTCCAGCAGA
TATGATTATATTTGCTATTGGACAAGAAGCAGAAGAAATAAAAGAATTAAAAGAAGCAGTAAAAGAAGTAGCTGCAACAA
AGGAAGTAACAACAGTAGAATTTAATGAAAAGGGAACAATTAAAACTATAGATTATAGTACTAATATAGAGGGCATATTT
GCCTCAGGAGATATAATTGAAGGAGATAAAACTGTTGTAAATGCTGTAAAAGAAGGAAAAGAAGCAGCAAAGGCCATAGT
AAAATATCTATTATCTAAGAAAGAAGGTGTAAGATAA

Upstream 100 bases:

>100_bases
AATAGACCATTTCTAAGTTAGAAATGGTCTATTTTTTTTGTTAAACTATTGTTATAACTGCAATTAACCTTTAAATATTA
AATATAAAGGAGGAATAATA

Downstream 100 bases:

>100_bases
TGAAAAAAAGAGATCTTTCTATAGAATTTTGTGGAGTAAAGTGTGAAAATCCATTTTTCTTATCATCGTCACCAGTAGGA
AACTGTTACGAAATGTGTGC

Product: pyridine nucleotide-disulfide oxidoreductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MENKLTYMKEREEVFTPLLAIEEASRCLLCHDAPCTKACPAGTNPGKFIRSLRFRNFNGAVATIRENNILGGVCARVCPT
DKYCEGACSRCGIDKPIQIGRLQRYLADYEQLTGIKILEAVQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEVKNQL
GGWLTYGIPEDRLPQKVVENEIGYIKNLGVHFRTNCKVGRDVSIDDLREEGFKAFLVAVGMQKSKDTEVKGNNLEGVVAG
TNFLAEAKTSKGKVKVGSKVIVIGGGDVAMDCAVTAKLLGSEDVKIVYRRTIERMPADRKEIAYTQDLNIPIFTGLKPAE
IVGQSGKVARFKATGMFDDSELNLPADMIIFAIGQEAEEIKELKEAVKEVAATKEVTTVEFNEKGTIKTIDYSTNIEGIF
ASGDIIEGDKTVVNAVKEGKEAAKAIVKYLLSKKEGVR

Sequences:

>Translated_438_residues
MENKLTYMKEREEVFTPLLAIEEASRCLLCHDAPCTKACPAGTNPGKFIRSLRFRNFNGAVATIRENNILGGVCARVCPT
DKYCEGACSRCGIDKPIQIGRLQRYLADYEQLTGIKILEAVQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEVKNQL
GGWLTYGIPEDRLPQKVVENEIGYIKNLGVHFRTNCKVGRDVSIDDLREEGFKAFLVAVGMQKSKDTEVKGNNLEGVVAG
TNFLAEAKTSKGKVKVGSKVIVIGGGDVAMDCAVTAKLLGSEDVKIVYRRTIERMPADRKEIAYTQDLNIPIFTGLKPAE
IVGQSGKVARFKATGMFDDSELNLPADMIIFAIGQEAEEIKELKEAVKEVAATKEVTTVEFNEKGTIKTIDYSTNIEGIF
ASGDIIEGDKTVVNAVKEGKEAAKAIVKYLLSKKEGVR
>Mature_438_residues
MENKLTYMKEREEVFTPLLAIEEASRCLLCHDAPCTKACPAGTNPGKFIRSLRFRNFNGAVATIRENNILGGVCARVCPT
DKYCEGACSRCGIDKPIQIGRLQRYLADYEQLTGIKILEAVQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEVKNQL
GGWLTYGIPEDRLPQKVVENEIGYIKNLGVHFRTNCKVGRDVSIDDLREEGFKAFLVAVGMQKSKDTEVKGNNLEGVVAG
TNFLAEAKTSKGKVKVGSKVIVIGGGDVAMDCAVTAKLLGSEDVKIVYRRTIERMPADRKEIAYTQDLNIPIFTGLKPAE
IVGQSGKVARFKATGMFDDSELNLPADMIIFAIGQEAEEIKELKEAVKEVAATKEVTTVEFNEKGTIKTIDYSTNIEGIF
ASGDIIEGDKTVVNAVKEGKEAAKAIVKYLLSKKEGVR

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli glutamate synthase [NADPH] small chain (GltD) and to E.coli AegA [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=450, Percent_Identity=30.6666666666667, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI237757300, Length=87, Percent_Identity=43.6781609195402, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1788468, Length=424, Percent_Identity=45.7547169811321, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1788811, Length=455, Percent_Identity=31.6483516483516, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1789606, Length=445, Percent_Identity=31.2359550561798, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87082180, Length=453, Percent_Identity=29.1390728476821, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1789243, Length=439, Percent_Identity=28.4738041002278, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71984108, Length=447, Percent_Identity=30.4250559284116, Blast_Score=175, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17570289, Length=462, Percent_Identity=27.9220779220779, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17543860, Length=209, Percent_Identity=28.2296650717703, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320030, Length=458, Percent_Identity=28.6026200873362, Blast_Score=136, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24640763, Length=437, Percent_Identity=30.4347826086957, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI18858217, Length=437, Percent_Identity=30.4347826086957, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28574881, Length=466, Percent_Identity=29.8283261802575, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24665539, Length=466, Percent_Identity=29.8283261802575, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24665547, Length=466, Percent_Identity=29.8283261802575, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24665543, Length=466, Percent_Identity=29.8283261802575, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR016040
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 47616; Mature: 47616

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKLTYMKEREEVFTPLLAIEEASRCLLCHDAPCTKACPAGTNPGKFIRSLRFRNFNGA
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCC
VATIRENNILGGVCARVCPTDKYCEGACSRCGIDKPIQIGRLQRYLADYEQLTGIKILEA
EEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
VQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEVKNQLGGWLTYGIPEDRLPQKVVEN
HHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEEHHHCCCEEEECCCCCCCHHHHHHH
EIGYIKNLGVHFRTNCKVGRDVSIDDLREEGFKAFLVAVGMQKSKDTEVKGNNLEGVVAG
HHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHEEHHHHCCCCCCCCCCCCCCCCEEEEC
TNFLAEAKTSKGKVKVGSKVIVIGGGDVAMDCAVTAKLLGSEDVKIVYRRTIERMPADRK
CCHHHHCCCCCCEEEECCEEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
EIAYTQDLNIPIFTGLKPAEIVGQSGKVARFKATGMFDDSELNLPADMIIFAIGQEAEEI
HCEEEECCCCEEECCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHEEEEECCCHHHH
KELKEAVKEVAATKEVTTVEFNEKGTIKTIDYSTNIEGIFASGDIIEGDKTVVNAVKEGK
HHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCEEEECCCEECCCHHHHHHHHHHH
EAAKAIVKYLLSKKEGVR
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MENKLTYMKEREEVFTPLLAIEEASRCLLCHDAPCTKACPAGTNPGKFIRSLRFRNFNGA
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCC
VATIRENNILGGVCARVCPTDKYCEGACSRCGIDKPIQIGRLQRYLADYEQLTGIKILEA
EEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
VQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEVKNQLGGWLTYGIPEDRLPQKVVEN
HHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEEHHHCCCEEEECCCCCCCHHHHHHH
EIGYIKNLGVHFRTNCKVGRDVSIDDLREEGFKAFLVAVGMQKSKDTEVKGNNLEGVVAG
HHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHEEHHHHCCCCCCCCCCCCCCCCEEEEC
TNFLAEAKTSKGKVKVGSKVIVIGGGDVAMDCAVTAKLLGSEDVKIVYRRTIERMPADRK
CCHHHHCCCCCCEEEECCEEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
EIAYTQDLNIPIFTGLKPAEIVGQSGKVARFKATGMFDDSELNLPADMIIFAIGQEAEEI
HCEEEECCCCEEECCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHEEEEECCCHHHH
KELKEAVKEVAATKEVTTVEFNEKGTIKTIDYSTNIEGIFASGDIIEGDKTVVNAVKEGK
HHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCEEEECCCEECCCHHHHHHHHHHH
EAAKAIVKYLLSKKEGVR
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]