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The map label for this gene is fosX [H]

Identifier: 226949474

GI number: 226949474

Start: 2488878

End: 2489291

Strand: Direct

Name: fosX [H]

Synonym: CLM_2407

Alternate gene names: 226949474

Gene position: 2488878-2489291 (Clockwise)

Preceding gene: 226949470

Following gene: 226949479

Centisome position: 59.9

GC content: 26.33

Gene sequence:

>414_bases
ATGATTGAATGCATAAGCCATATTACTTTTGTTGTGAAAAATTTAGATAAAACTACTCAGTTATTTAAAGAACTATTTAA
TGCTAAAGAAGTTTATTATAGTGGTGAAAAAAAGCATTCTTTATTTAAAGAGCGTTTTTTTGTTATTGGTAGTCAGTGGA
TAGCTGTTATGGAAGATACAAATATACTTAACAGAACTTATCATCATATAGCATTTAAAATATCAGATTCTGATGTAGAT
AGTTATTTGGATAAAATTAAAACTCTAAATTTAGAATTAAAGCCTCCAAGGGAAAGAGTATCTGGGGAAGGCTATTCTAT
ATACTTTTATGACTATGATAATAATTTATTTGAACTTCACACAGAAACATTGGAGAAAAGATTAGCTTCGTATACAAAGA
TAGATAATATATAA

Upstream 100 bases:

>100_bases
ATTTTCACATAATGATATACAAATTAATGCTATAATTAAAACATGAACAAACTATAACGAAATACGAATTGGTTAGATAA
GACAGGGGGGGAAGGTATAT

Downstream 100 bases:

>100_bases
ACTATATTTAATTAATTCGTATTCTTAAAATATAAATTAAGGAAAGTCATTTCTGGCTTTCCTTAAAAATTGATATATTA
TCAACATTATTCTAAAACAT

Product: fosfomycin resistance protein FosX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MIECISHITFVVKNLDKTTQLFKELFNAKEVYYSGEKKHSLFKERFFVIGSQWIAVMEDTNILNRTYHHIAFKISDSDVD
SYLDKIKTLNLELKPPRERVSGEGYSIYFYDYDNNLFELHTETLEKRLASYTKIDNI

Sequences:

>Translated_137_residues
MIECISHITFVVKNLDKTTQLFKELFNAKEVYYSGEKKHSLFKERFFVIGSQWIAVMEDTNILNRTYHHIAFKISDSDVD
SYLDKIKTLNLELKPPRERVSGEGYSIYFYDYDNNLFELHTETLEKRLASYTKIDNI
>Mature_137_residues
MIECISHITFVVKNLDKTTQLFKELFNAKEVYYSGEKKHSLFKERFFVIGSQWIAVMEDTNILNRTYHHIAFKISDSDVD
SYLDKIKTLNLELKPPRERVSGEGYSIYFYDYDNNLFELHTETLEKRLASYTKIDNI

Specific function: Catalyzes the hydration of fosfomycin [H]

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fosfomycin resistance protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 16261; Mature: 16261

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIECISHITFVVKNLDKTTQLFKELFNAKEVYYSGEKKHSLFKERFFVIGSQWIAVMEDT
CHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCC
NILNRTYHHIAFKISDSDVDSYLDKIKTLNLELKPPRERVSGEGYSIYFYDYDNNLFELH
HHHHHHEEEEEEEECCCCHHHHHHHHHHCCEEECCCHHHHCCCCEEEEEEECCCCEEEHH
TETLEKRLASYTKIDNI
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIECISHITFVVKNLDKTTQLFKELFNAKEVYYSGEKKHSLFKERFFVIGSQWIAVMEDT
CHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCC
NILNRTYHHIAFKISDSDVDSYLDKIKTLNLELKPPRERVSGEGYSIYFYDYDNNLFELH
HHHHHHEEEEEEEECCCCHHHHHHHHHHCCEEECCCHHHHCCCCEEEEEEECCCCEEEHH
TETLEKRLASYTKIDNI
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]