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The map label for this gene is bcrA [H]

Identifier: 226949470

GI number: 226949470

Start: 2483195

End: 2484886

Strand: Direct

Name: bcrA [H]

Synonym: CLM_2403

Alternate gene names: 226949470

Gene position: 2483195-2484886 (Clockwise)

Preceding gene: 226949469

Following gene: 226949474

Centisome position: 59.76

GC content: 30.73

Gene sequence:

>1692_bases
ATGTTTGCATATACTTGTAAATATGCCCCCCTTTCTATACTTGAGACTTTTGATGAAGTCCCTATAAAAATAAATCCTAT
AGCATATACCTTTGATAAAGCTGATGTACTTATGCACCCAAATATGTGTACATATTGCAAGTCTCTACTTGAAAATCTTA
TTGATTGTAATAGTGATCAGTTAATATTGATGAACTGCTGTGACAGCATGAGGAGACTATATGATGTTTTAAAATCCCAA
TCAAGTATTAAATATTTATATATGATGGACTTGCCTCACAAAAACAATTGTTGTTCACGTGTTTTACTTAAAGAGTCCTT
TATGAAATTTATAAATAATTACGAGAAATTTAGTGGAAAAAAGTTTAATATTGAAAATTTTAAACTATCTATTAAAAATC
ATATCGTTAGTAACAGTAGCTATAAAAATAATTTTAATAATAGAATTGCCATTCTAGGTGGTAGATGTGATGATTCTCTT
GTAAACATGATAGAAAACTGCACTGGATCATCAGTATTAAACCTTACATGTACAGGAGAAAATTTCATATTAGATAAATC
ACCGGATTTTTCTTCTATGAATGAACTGATTTTATGGTATGCTGAAGCTATTTTATCTCAAGCTCCTTGCATGAGAATGT
CTGATATTTCCTACAGGAAAAAACTTATTCTTTCTAATAATATATCAGGAATTATCTATAACACAGTAAAATTCTGCGAT
TATTATTCCTTTGAATATGCATCAATTAAAAAGAAAATTAATATTCCCATACTAAAGATTGAAACTGATTATACTAATCA
AAGTAGAGGACAACTTAAAACCAGAATAGAGGCTTTTATTGAAAGACTAAAAGATAAAAGAAAAATAAGCTACAAAACTT
TGTCCAATCTAGAAGATAACTACTATGTGGCAGGCATTGATAGTGGATCCACTTCCACAAATATAGTAATTTTAGATAAA
GATAAAAATATAATCAGCTACTCCATAGTAAGCACTGGTGCTAAAAGTATTTATGGTGCCGAAGCTGCACTAGATACTGC
TTTAAGAGAGGCTCATCTTTCAAAAGATGATCTTAAATATATTATTTCCACTGGGTATGGTAGGGTAAATATTCCTTTTG
CCAATGAAAGTGTTACTGAAATAACCTGTCATGGTATTGCAGCTCATCATTTAAATCCTAGTATAAGAACAGTTATGGAT
ATTGGAGGTCAAGACAGTAAAGTAATAAAATTAGATGAAAAGGGTAATATTAAAGACTTTGCCATGAACGACAAATGTGC
TGCAGGTACAGGCCGATTTCTTGATATGATGGCTAGAACTCTCCAAATAAGCATTGATGAAATGAGTAAGGAAGGACTTC
ATTGGGAGGAAGAACTTAAAATAACCAATATGTGTACCGTATTTGCAGAATCAGAAGTAGTTTCACTTATAGCTGAAAAC
AAGGAAAAATGTGATATAATACATGGACTTAATGATTCCATAGCTTCAAAAATGCTATCATTATTAAATAGAGTAGGTAA
AAAGGATGCCTATATGATGACTGGAGGTGTAGCAAAAAATCTAGGAGTGGTAAGAGCTTTAGAAACAAAACTTAAAAGCA
AAATATTTATATGTAAGGAACCTCAAATATGTGGTTCTCTAGGTGCTGCTTTAATAGCCCTTAAAAAGTATGAAGAGGCT
TTTTCAAAATAA

Upstream 100 bases:

>100_bases
GAGATGGAGTTGATAGACGAAATTCTCATGATGGTCAACTTCGTACCAGATTAGAAGCATTTTTTGAAATTTTAAAAAAT
AATGAAGGAGGTATTTAAAT

Downstream 100 bases:

>100_bases
AATATTTTAATTTTAAATATAGAGCAAAGATAAAAAATACATGTAATAAATGAAATCAATTGGTTTATATATTTTTTTAT
CTTTGCCTTTTTAAAATTAA

Product: benzoyl-CoA reductase subunit A

Products: NA

Alternate protein names: 2-hydroxyglutaryl-CoA dehydratase component A [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MFAYTCKYAPLSILETFDEVPIKINPIAYTFDKADVLMHPNMCTYCKSLLENLIDCNSDQLILMNCCDSMRRLYDVLKSQ
SSIKYLYMMDLPHKNNCCSRVLLKESFMKFINNYEKFSGKKFNIENFKLSIKNHIVSNSSYKNNFNNRIAILGGRCDDSL
VNMIENCTGSSVLNLTCTGENFILDKSPDFSSMNELILWYAEAILSQAPCMRMSDISYRKKLILSNNISGIIYNTVKFCD
YYSFEYASIKKKINIPILKIETDYTNQSRGQLKTRIEAFIERLKDKRKISYKTLSNLEDNYYVAGIDSGSTSTNIVILDK
DKNIISYSIVSTGAKSIYGAEAALDTALREAHLSKDDLKYIISTGYGRVNIPFANESVTEITCHGIAAHHLNPSIRTVMD
IGGQDSKVIKLDEKGNIKDFAMNDKCAAGTGRFLDMMARTLQISIDEMSKEGLHWEEELKITNMCTVFAESEVVSLIAEN
KEKCDIIHGLNDSIASKMLSLLNRVGKKDAYMMTGGVAKNLGVVRALETKLKSKIFICKEPQICGSLGAALIALKKYEEA
FSK

Sequences:

>Translated_563_residues
MFAYTCKYAPLSILETFDEVPIKINPIAYTFDKADVLMHPNMCTYCKSLLENLIDCNSDQLILMNCCDSMRRLYDVLKSQ
SSIKYLYMMDLPHKNNCCSRVLLKESFMKFINNYEKFSGKKFNIENFKLSIKNHIVSNSSYKNNFNNRIAILGGRCDDSL
VNMIENCTGSSVLNLTCTGENFILDKSPDFSSMNELILWYAEAILSQAPCMRMSDISYRKKLILSNNISGIIYNTVKFCD
YYSFEYASIKKKINIPILKIETDYTNQSRGQLKTRIEAFIERLKDKRKISYKTLSNLEDNYYVAGIDSGSTSTNIVILDK
DKNIISYSIVSTGAKSIYGAEAALDTALREAHLSKDDLKYIISTGYGRVNIPFANESVTEITCHGIAAHHLNPSIRTVMD
IGGQDSKVIKLDEKGNIKDFAMNDKCAAGTGRFLDMMARTLQISIDEMSKEGLHWEEELKITNMCTVFAESEVVSLIAEN
KEKCDIIHGLNDSIASKMLSLLNRVGKKDAYMMTGGVAKNLGVVRALETKLKSKIFICKEPQICGSLGAALIALKKYEEA
FSK
>Mature_563_residues
MFAYTCKYAPLSILETFDEVPIKINPIAYTFDKADVLMHPNMCTYCKSLLENLIDCNSDQLILMNCCDSMRRLYDVLKSQ
SSIKYLYMMDLPHKNNCCSRVLLKESFMKFINNYEKFSGKKFNIENFKLSIKNHIVSNSSYKNNFNNRIAILGGRCDDSL
VNMIENCTGSSVLNLTCTGENFILDKSPDFSSMNELILWYAEAILSQAPCMRMSDISYRKKLILSNNISGIIYNTVKFCD
YYSFEYASIKKKINIPILKIETDYTNQSRGQLKTRIEAFIERLKDKRKISYKTLSNLEDNYYVAGIDSGSTSTNIVILDK
DKNIISYSIVSTGAKSIYGAEAALDTALREAHLSKDDLKYIISTGYGRVNIPFANESVTEITCHGIAAHHLNPSIRTVMD
IGGQDSKVIKLDEKGNIKDFAMNDKCAAGTGRFLDMMARTLQISIDEMSKEGLHWEEELKITNMCTVFAESEVVSLIAEN
KEKCDIIHGLNDSIASKMLSLLNRVGKKDAYMMTGGVAKNLGVVRALETKLKSKIFICKEPQICGSLGAALIALKKYEEA
FSK

Specific function: Required for the activation of (R)-2-hydroxyglutaryl-CoA dehydratase. This protein is extremely sensitive towards oxygen [H]

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yjiL and M.jannaschii MJ0004 and MJ0800 [H]

Homologues:

Organism=Escherichia coli, GI87082426, Length=254, Percent_Identity=40.1574803149606, Blast_Score=177, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 63427; Mature: 63427

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAYTCKYAPLSILETFDEVPIKINPIAYTFDKADVLMHPNMCTYCKSLLENLIDCNSDQ
CCEEEECCCCHHHHHHHCCCCEEECCEEEEECCCCEEECCCHHHHHHHHHHHHHCCCCCC
LILMNCCDSMRRLYDVLKSQSSIKYLYMMDLPHKNNCCSRVLLKESFMKFINNYEKFSGK
EEHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KFNIENFKLSIKNHIVSNSSYKNNFNNRIAILGGRCDDSLVNMIENCTGSSVLNLTCTGE
EEECCCEEEEEEHHEECCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCEEEEEECCC
NFILDKSPDFSSMNELILWYAEAILSQAPCMRMSDISYRKKLILSNNISGIIYNTVKFCD
EEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEECCCCCEEEEHHHHHHH
YYSFEYASIKKKINIPILKIETDYTNQSRGQLKTRIEAFIERLKDKRKISYKTLSNLEDN
CCCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YYVAGIDSGSTSTNIVILDKDKNIISYSIVSTGAKSIYGAEAALDTALREAHLSKDDLKY
EEEEEECCCCCCEEEEEEECCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
IISTGYGRVNIPFANESVTEITCHGIAAHHLNPSIRTVMDIGGQDSKVIKLDEKGNIKDF
HEECCCCEEEECCCCCCCEEEEECCEEEECCCCHHHHHHHCCCCCCEEEEECCCCCCCEE
AMNDKCAAGTGRFLDMMARTLQISIDEMSKEGLHWEEELKITNMCTVFAESEVVSLIAEN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHEEHHHHEEEHHHHHHHHHHHCC
KEKCDIIHGLNDSIASKMLSLLNRVGKKDAYMMTGGVAKNLGVVRALETKLKSKIFICKE
CHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCEEEEECC
PQICGSLGAALIALKKYEEAFSK
CCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFAYTCKYAPLSILETFDEVPIKINPIAYTFDKADVLMHPNMCTYCKSLLENLIDCNSDQ
CCEEEECCCCHHHHHHHCCCCEEECCEEEEECCCCEEECCCHHHHHHHHHHHHHCCCCCC
LILMNCCDSMRRLYDVLKSQSSIKYLYMMDLPHKNNCCSRVLLKESFMKFINNYEKFSGK
EEHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KFNIENFKLSIKNHIVSNSSYKNNFNNRIAILGGRCDDSLVNMIENCTGSSVLNLTCTGE
EEECCCEEEEEEHHEECCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCEEEEEECCC
NFILDKSPDFSSMNELILWYAEAILSQAPCMRMSDISYRKKLILSNNISGIIYNTVKFCD
EEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEECCCCCEEEEHHHHHHH
YYSFEYASIKKKINIPILKIETDYTNQSRGQLKTRIEAFIERLKDKRKISYKTLSNLEDN
CCCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YYVAGIDSGSTSTNIVILDKDKNIISYSIVSTGAKSIYGAEAALDTALREAHLSKDDLKY
EEEEEECCCCCCEEEEEEECCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
IISTGYGRVNIPFANESVTEITCHGIAAHHLNPSIRTVMDIGGQDSKVIKLDEKGNIKDF
HEECCCCEEEECCCCCCCEEEEECCEEEECCCCHHHHHHHCCCCCCEEEEECCCCCCCEE
AMNDKCAAGTGRFLDMMARTLQISIDEMSKEGLHWEEELKITNMCTVFAESEVVSLIAEN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHEEHHHHEEEHHHHHHHHHHHCC
KEKCDIIHGLNDSIASKMLSLLNRVGKKDAYMMTGGVAKNLGVVRALETKLKSKIFICKE
CHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCEEEEECC
PQICGSLGAALIALKKYEEAFSK
CCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8365476; 2659350; 7607244; 11106419; 11243821 [H]