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The map label for this gene is xerC [H]

Identifier: 226949169

GI number: 226949169

Start: 2143403

End: 2144395

Strand: Reverse

Name: xerC [H]

Synonym: CLM_2087

Alternate gene names: 226949169

Gene position: 2144395-2143403 (Counterclockwise)

Preceding gene: 226949170

Following gene: 226949168

Centisome position: 51.61

GC content: 26.69

Gene sequence:

>993_bases
ATGCAAAAAATCAATTTAAAAATTGATGAATTTATGATTTATTGTGAATCAAAAAATTTATCTAAAAAAACAATGATGAG
TTATGAGCAAACTCTAAGATTGTTTACTAAATATTTAGAGGAAGAAAAAGGTATTGGAGATGTTAAAAAAGTTACAGAAA
AAATGATAAGAGAATATATAAATTATACAAAAAATAGAGGTAAATACACAATAGTTGGAGATAAAGAAACTTTAAAAACT
AATACACCAGAAATGCGTAAAGATTATGGGAAAAAAGTTTCTATAACAACAATAAACAATTATATTAGAAATATTAAAGT
GTTTTTTAATTTTTTATTAGAACAAAGCTATATAAAAAAGGATGTAGTAAAAAACATTAAACAATTTAAAAATCAAAGAA
AAGCAAAAGAATTTATTACAGATAGTCAGTTTGCAGAGCTATTAAGACATATAGATACAACAAAATTCCACGAAAGACGT
GACCATCTATGCATAATGCTGCTATTGGATACAGGCATGAGAATAGGAGAATGTTTAGAAATAAAAGTAGAAAATATAGA
TATGAATTATAGGAGCATACTGTTACCTGCAGAGGATACAAAAGGAAAAAGGGATAGATATGTTTATTTTAGTCAAGTTA
TGAACAAGGAACTTCGCAGATGGCTTCAATATAAAGATAGATATGTAGAATCAGATTATTTATTTTGTACTACCAAAGGT
ACTCCTGTGTTAATTAGAACATTTGAAAGAAAATTAAAGGATTATGCGAATAGAGCAGGTTTAAAAGATATTCATCCTCA
TCAATTGAGAAATAATTTCGCAAAAAGATTTTTAATGTCAGGCGGGTCGATTTATATTCTATCTCAAGTTTTAGGACATT
CATCTGTTAAAGTGACAGAGCAAGCGTATTTAGACTTAACAGATACAGATATAAGAAAAAATTATCAACAATTTTCACCT
CTAGCAAATATGAAAAGGGGAGGTAAATATTAA

Upstream 100 bases:

>100_bases
TTATGCAAAATCACAAATTGGCAATATATGTGTATTAATCTTCAAAAAAATACTAATAGACTTTCTTCATTCATAGGTAG
AATGAAGGGGGTCTATTTTT

Downstream 100 bases:

>100_bases
TGACTAACTATACAATTACCTCCAATTTCGATATTACTAATTTAAAACTTTCTGACGGTGCTTATCGTTGCTATATGCTG
CTTCAGCATCTTGCTTATGG

Product: phage integrase family site-specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MQKINLKIDEFMIYCESKNLSKKTMMSYEQTLRLFTKYLEEEKGIGDVKKVTEKMIREYINYTKNRGKYTIVGDKETLKT
NTPEMRKDYGKKVSITTINNYIRNIKVFFNFLLEQSYIKKDVVKNIKQFKNQRKAKEFITDSQFAELLRHIDTTKFHERR
DHLCIMLLLDTGMRIGECLEIKVENIDMNYRSILLPAEDTKGKRDRYVYFSQVMNKELRRWLQYKDRYVESDYLFCTTKG
TPVLIRTFERKLKDYANRAGLKDIHPHQLRNNFAKRFLMSGGSIYILSQVLGHSSVKVTEQAYLDLTDTDIRKNYQQFSP
LANMKRGGKY

Sequences:

>Translated_330_residues
MQKINLKIDEFMIYCESKNLSKKTMMSYEQTLRLFTKYLEEEKGIGDVKKVTEKMIREYINYTKNRGKYTIVGDKETLKT
NTPEMRKDYGKKVSITTINNYIRNIKVFFNFLLEQSYIKKDVVKNIKQFKNQRKAKEFITDSQFAELLRHIDTTKFHERR
DHLCIMLLLDTGMRIGECLEIKVENIDMNYRSILLPAEDTKGKRDRYVYFSQVMNKELRRWLQYKDRYVESDYLFCTTKG
TPVLIRTFERKLKDYANRAGLKDIHPHQLRNNFAKRFLMSGGSIYILSQVLGHSSVKVTEQAYLDLTDTDIRKNYQQFSP
LANMKRGGKY
>Mature_330_residues
MQKINLKIDEFMIYCESKNLSKKTMMSYEQTLRLFTKYLEEEKGIGDVKKVTEKMIREYINYTKNRGKYTIVGDKETLKT
NTPEMRKDYGKKVSITTINNYIRNIKVFFNFLLEQSYIKKDVVKNIKQFKNQRKAKEFITDSQFAELLRHIDTTKFHERR
DHLCIMLLLDTGMRIGECLEIKVENIDMNYRSILLPAEDTKGKRDRYVYFSQVMNKELRRWLQYKDRYVESDYLFCTTKG
TPVLIRTFERKLKDYANRAGLKDIHPHQLRNNFAKRFLMSGGSIYILSQVLGHSSVKVTEQAYLDLTDTDIRKNYQQFSP
LANMKRGGKY

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=330, Percent_Identity=20.6060606060606, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789261, Length=324, Percent_Identity=21.9135802469136, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790767, Length=176, Percent_Identity=26.7045454545455, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 39318; Mature: 39318

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKINLKIDEFMIYCESKNLSKKTMMSYEQTLRLFTKYLEEEKGIGDVKKVTEKMIREYI
CCCCCEEHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NYTKNRGKYTIVGDKETLKTNTPEMRKDYGKKVSITTINNYIRNIKVFFNFLLEQSYIKK
HHHCCCCCEEEECCCHHHCCCCCHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
DVVKNIKQFKNQRKAKEFITDSQFAELLRHIDTTKFHERRDHLCIMLLLDTGMRIGECLE
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHHHHHCCEEEEEEHHCCCCCCCEEE
IKVENIDMNYRSILLPAEDTKGKRDRYVYFSQVMNKELRRWLQYKDRYVESDYLFCTTKG
EEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
TPVLIRTFERKLKDYANRAGLKDIHPHQLRNNFAKRFLMSGGSIYILSQVLGHSSVKVTE
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEHH
QAYLDLTDTDIRKNYQQFSPLANMKRGGKY
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQKINLKIDEFMIYCESKNLSKKTMMSYEQTLRLFTKYLEEEKGIGDVKKVTEKMIREYI
CCCCCEEHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NYTKNRGKYTIVGDKETLKTNTPEMRKDYGKKVSITTINNYIRNIKVFFNFLLEQSYIKK
HHHCCCCCEEEECCCHHHCCCCCHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
DVVKNIKQFKNQRKAKEFITDSQFAELLRHIDTTKFHERRDHLCIMLLLDTGMRIGECLE
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHHHHHCCEEEEEEHHCCCCCCCEEE
IKVENIDMNYRSILLPAEDTKGKRDRYVYFSQVMNKELRRWLQYKDRYVESDYLFCTTKG
EEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
TPVLIRTFERKLKDYANRAGLKDIHPHQLRNNFAKRFLMSGGSIYILSQVLGHSSVKVTE
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEHH
QAYLDLTDTDIRKNYQQFSPLANMKRGGKY
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA