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The map label for this gene is nuoG [C]

Identifier: 226949091

GI number: 226949091

Start: 2074173

End: 2075906

Strand: Reverse

Name: nuoG [C]

Synonym: CLM_2007

Alternate gene names: 226949091

Gene position: 2075906-2074173 (Counterclockwise)

Preceding gene: 226949092

Following gene: 226949090

Centisome position: 49.96

GC content: 34.08

Gene sequence:

>1734_bases
ATGAGTTTAGTAACTTTAAATATAAATGGCAAAGAGCTTAAGGTAGAGAAGGGAACTACTATATTAGATGCAGCAAAACT
TTTAAATATAAATATACCAACTCTATGTAATTTTCATCTTAATGATAATAGAACAGAAAACAAACCTGGTTCCTGTAGGG
TCTGTGTAGTAGAAGTAGAGGGGAGAAAAAACTTAGCGCCAGCCTGTTGTACCCCTGTATGGGAAGGAATGATAGTAAAA
ACTAATTCCATAAGGGCTATAAAAGCTAGAAGAGCTATAGTAGAATTACTTTTATCCGATCATCCAAAAGACTGTTTGCT
TTGTGAGAAAAATACAAAATGTGAACTGCAGAAATTAGCTGCAGATATGGGTATAAGAGAAATGAAATATCAAGGTGATG
TTTCAATGTATCCTATAGATATTTCTAGCTATTCCATAGTTAGAGATATGGATAAATGTATACTTTGTAGAAGATGCATA
ACTATGTGTAATGAAGTTCAAACTGTAGGAACCCTATCTGCTATTGGAAGAGGTTTTGAAACTGTAGTAGCACCAGCCTT
TTCTGAAGCTATAAAAAATACTAATTGTACTTTCTGTGGACAATGTGTTTCTGTCTGTCCAACTGGGGCTTTAACAGAAG
TAAATAATACAAGTAAAGTTTGGGATGCACTATCACAAAAGGATAAAGTTGTTATTGTACAAACTGCTCCAGCTATTAGA
GCTGCTTTAGGTGAAGAATTTGGATTAGAACCTGGAACAGCTGTTACAGGAAAAATGGTAGCAGCTCTTCGCCAATTAGG
ATTCAGTAAAGTTTTTGATACAGATTTTGCAGCAGACTTGACTATTATGGAGGAAGCTTCAGAATTTATTCATAGATTAG
AGCATGGTGGAACACTTCCAATGCTTACAAGTTGTTGTCCGGGATGGATAAAATTCTTTGAACACAACTTTAATGATTTA
ATGGATATACCATCTAGTTGTAAGTCTCCTCAGCAAATGTTTGGAGCTATAGCTAAAAGTTATTTAGCAGAAAAAATGAA
GGTAGATCCTAAAGATATTATAGTAGTATCTGTAATGCCCTGTCTTGCTAAAAAGTATGAGGCAAAAAGAGAAGAAATGA
AGAGAAATGGAATTCCTGATGTAGACATTGTTATAAGTACAAGAGAATTAGCTAAAATGATAGTAGAAGCGGGTATAGAT
TTTAATTCTCTACAGGAGGAAGAATTTGATAATCCACTAGGTGAATCTACAGGGGCTTCAGTAATTTTTGGAACTACCGG
CGGTGTTATGGAAGCGGCTTTAAGAACTGCCTATGAATGGGTTACTAAAGGTACTTTAAAAGATGTAGAATTTATAGAAG
TTCGTGGGGAAGATGGCATAAGAGAAGCTACAGTAAACATAAAGGATACAGAGGTTAAAGTAGCTATAGCTAGTGGATTA
GGTAATGCTAGAAAACTTTTAAATGATATAAGAAATGGAAAGTCTAAATATCATATGATCGAAATCATGGCGTGTCCATC
AGGCTGTGTAGATGGTGGTGGTCAACCTTATATCTATGGAGATACAAATATATTGAAAAAAAGAACAGAAGCCCTATATA
AAGAAGATAGTAATAAAGAAATAAGGAAGTCTCACGAAAATCCATATATAAAGAAACTTTATGAAGAATATTTAGGTAAA
CCTTATGGTGAAAAAGCTCATGAACTTCTGCATACTAAATATAGAGTTAGATAA

Upstream 100 bases:

>100_bases
CATTTTATAAATCAAGAAAAATGTATTAAATGTGGAAATTGTTATAGTGCTTGTCCAGTTGGAGCTATTATAAAGAAATA
GGAAGAAAGAGGTGAATAAG

Downstream 100 bases:

>100_bases
CATGAAATAAACACAAATTTTCCTATTAATATACACCAAATAAAACCAGTATCAGTATGGTTTGAAACTATAATCAGTTA
TAAGTTTAAAGTAATTTCCT

Product: iron hydrogenase 1

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 577; Mature: 576

Protein sequence:

>577_residues
MSLVTLNINGKELKVEKGTTILDAAKLLNINIPTLCNFHLNDNRTENKPGSCRVCVVEVEGRKNLAPACCTPVWEGMIVK
TNSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLAADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCI
TMCNEVQTVGTLSAIGRGFETVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKVVIVQTAPAIR
AALGEEFGLEPGTAVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLPMLTSCCPGWIKFFEHNFNDL
MDIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMPCLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGID
FNSLQEEEFDNPLGESTGASVIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGL
GNARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKEIRKSHENPYIKKLYEEYLGK
PYGEKAHELLHTKYRVR

Sequences:

>Translated_577_residues
MSLVTLNINGKELKVEKGTTILDAAKLLNINIPTLCNFHLNDNRTENKPGSCRVCVVEVEGRKNLAPACCTPVWEGMIVK
TNSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLAADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCI
TMCNEVQTVGTLSAIGRGFETVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKVVIVQTAPAIR
AALGEEFGLEPGTAVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLPMLTSCCPGWIKFFEHNFNDL
MDIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMPCLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGID
FNSLQEEEFDNPLGESTGASVIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGL
GNARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKEIRKSHENPYIKKLYEEYLGK
PYGEKAHELLHTKYRVR
>Mature_576_residues
SLVTLNINGKELKVEKGTTILDAAKLLNINIPTLCNFHLNDNRTENKPGSCRVCVVEVEGRKNLAPACCTPVWEGMIVKT
NSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLAADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCIT
MCNEVQTVGTLSAIGRGFETVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKVVIVQTAPAIRA
ALGEEFGLEPGTAVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLPMLTSCCPGWIKFFEHNFNDLM
DIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMPCLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGIDF
NSLQEEEFDNPLGESTGASVIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGLG
NARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKEIRKSHENPYIKKLYEEYLGKP
YGEKAHELLHTKYRVR

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=402, Percent_Identity=29.8507462686567, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI6912524, Length=402, Percent_Identity=28.3582089552239, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI134284357, Length=363, Percent_Identity=29.2011019283747, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI84452151, Length=363, Percent_Identity=29.2011019283747, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI14165461, Length=450, Percent_Identity=27.1111111111111, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI33519475, Length=224, Percent_Identity=30.3571428571429, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI145693161, Length=246, Percent_Identity=26.4227642276423, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71995015, Length=403, Percent_Identity=31.2655086848635, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17565758, Length=225, Percent_Identity=32, Blast_Score=118, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI32566231, Length=225, Percent_Identity=32, Blast_Score=118, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI193209088, Length=255, Percent_Identity=31.7647058823529, Blast_Score=116, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324089, Length=394, Percent_Identity=25.6345177664975, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI116007470, Length=373, Percent_Identity=31.6353887399464, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI116007466, Length=373, Percent_Identity=31.6353887399464, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI116007464, Length=373, Percent_Identity=31.6353887399464, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI116007468, Length=373, Percent_Identity=31.6353887399464, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI116007462, Length=287, Percent_Identity=33.4494773519164, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24640559, Length=205, Percent_Identity=33.6585365853659, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24640557, Length=205, Percent_Identity=33.6585365853659, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 63855; Mature: 63723

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVTLNINGKELKVEKGTTILDAAKLLNINIPTLCNFHLNDNRTENKPGSCRVCVVEVE
CEEEEEECCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEC
GRKNLAPACCTPVWEGMIVKTNSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLA
CCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
ADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCITMCNEVQTVGTLSAIGRGFE
HHCCHHHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKVVIVQTAPAIR
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCHHHH
AALGEEFGLEPGTAVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLP
HHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCH
MLTSCCPGWIKFFEHNFNDLMDIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMP
HHHHCCHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHH
CLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGIDFNSLQEEEFDNPLGESTGAS
HHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCHHHCCHHHCCCCCCCCCCCE
VIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGL
EEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEECCEEEEEEECCC
GNARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKE
CHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHH
IRKSHENPYIKKLYEEYLGKPYGEKAHELLHTKYRVR
HHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLVTLNINGKELKVEKGTTILDAAKLLNINIPTLCNFHLNDNRTENKPGSCRVCVVEVE
EEEEEECCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEC
GRKNLAPACCTPVWEGMIVKTNSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLA
CCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
ADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCITMCNEVQTVGTLSAIGRGFE
HHCCHHHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKVVIVQTAPAIR
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCHHHH
AALGEEFGLEPGTAVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLP
HHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCH
MLTSCCPGWIKFFEHNFNDLMDIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMP
HHHHCCHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHH
CLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGIDFNSLQEEEFDNPLGESTGAS
HHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCHHHCCHHHCCCCCCCCCCCE
VIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGL
EEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEECCEEEEEEECCC
GNARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKE
CHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHH
IRKSHENPYIKKLYEEYLGKPYGEKAHELLHTKYRVR
HHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]