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The map label for this gene is yfmM [H]

Identifier: 226949090

GI number: 226949090

Start: 2072255

End: 2073811

Strand: Reverse

Name: yfmM [H]

Synonym: CLM_2006

Alternate gene names: 226949090

Gene position: 2073811-2072255 (Counterclockwise)

Preceding gene: 226949091

Following gene: 226949089

Centisome position: 49.91

GC content: 31.98

Gene sequence:

>1557_bases
ATGAGTATATTAACCGTTAAGGATATTAGCCATGGATTTGGAGACAGAGCTATTTTCGAGGAAGTATCCTTTAGACTTTT
AAAGGGAGAGCATGTAGGGCTTATTGGAGCTAATGGAGAGGGTAAGTCTACATTTATGAATATAATAACAGGAAAATTAA
TGCCAGATGAGGGTAAAATTCAATGGGCAAAGGATGTAAGAATAGGCTACATGGATCAGCATTTAAATCTTACAAAGGGA
AAAACCATTAGAGAAGTCTTGAGGGAAGCCTTTGACTATTTATTTAATCTTGAAAAAGAAATGAATGATTTATACATGAA
AATGGGAGAGGTATCCCAGGAAGAAATGGAAAAAATGCTAAATAGAACAGCTACTATACAGGATATGTTAGATCATAATG
ATTTTTACATAATAGATGCTAAAATAGAGGAAATAGCAAGGGGACTTGGTATTGCTGACATAGGTTTGGATAAGGATGTA
TCAGATTTATCTGGAGGACAAAGGACAAAAATACTTCTAGCAAAACTCCTTTTAGAGAATCCAGATATATTACTTTTAGA
TGAGCCCACAAACTATTTAGACGAAGATCACATAGATTGGCTTAAAAATTATCTTAAAAACTATGAGAATGCCTTTATTT
TAATATCCCATGATATACCATTTTTAAATGAGGTAATAAATTTAATTTATCATGTAGAAAATAAAAGACTTACTCGTTAC
GTAGGGGATTATAATGAATTTAGAAGAATTTATGAGGAAAACAAGAAACGACTAGAGGCAGCCTATGAAAGACAACAGGC
AGAAATATCAAAACTAGAAGATTTTATAGCAAAAAATAAAGCAAGAGTTTCCACCGTAGGTATGGCAAGATCTAGACAAA
AAAAATTAGATAAAATAGATAAAATAGAACTTACAAAAGAAAAACCAAAGCCGGAATTTAATTTTAAACAGGCTAGAGCT
TCTGGAAAAGTTATATTTGAAACTAAAGATTTAGTTATAGGCTATGATTCACCCTTAACAAAACCTTTAAATATAAAAAT
GGAAAGAGGACAAAAGGTAGCGTTAGTAGGAGCCAATGGTCTTGGAAAAACTACATTACTAAAAAGTTTATTAGGAGCTA
TAAAACCATTGGAAGGGGATGTTACGCTAGGTGATTATCAATACATAGGATATTTTGAGCAAGAAGAAAGAGAATCTAAT
TATAATACCTGTATAGAAGAAGTGTGGAAAGAGTTCCCTGTATTTACTCAATACGAAATAAGATCTGCCCTAGCAAAATG
TGGATTAACTACGAAGCAATTAGAATCTAAAATAGTAGTGCTGTCCGGTGGAGAAGCAGCAAAGGTAAGGCTTTGTAAAA
TACTAAATAGAGAAACCAATATACTAATATTAGACGAACCTACTAACCACTTAGATGTGGAAGCCAAAGAAGAATTAAAA
AGAGCATTAAAAGAATATAAAGGTTCTATACTTTTAGTTTGCCACGAAAAAGAATTTTATGAAGATATAGTAACAGAAAC
TTGGAATTGTGAAAGCTGGACAACTAAGATAGTATAA

Upstream 100 bases:

>100_bases
TAAAAAGAAACTAAATTTATATTTTAAATAAATTATTGACAAGGCTTTATTTATAAATTAAAGTTTATTTTAGATTATAT
TTTCAGGAGGATTTTTACAT

Downstream 100 bases:

>100_bases
TGCAACCATAGATAATAAGATTCACTATAAAGCTGCAAAGTATGAACAACTAAAATTGTATAATGTATCTAGAAAAACAG
TCAGTGTTTATTAAAGCTGG

Product: drug resistance ABC transporter RA1 family, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MSILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKIQWAKDVRIGYMDQHLNLTKG
KTIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMEKMLNRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDV
SDLSGGQRTKILLAKLLLENPDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
VGDYNEFRRIYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKIDKIELTKEKPKPEFNFKQARA
SGKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANGLGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESN
YNTCIEEVWKEFPVFTQYEIRSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
RALKEYKGSILLVCHEKEFYEDIVTETWNCESWTTKIV

Sequences:

>Translated_518_residues
MSILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKIQWAKDVRIGYMDQHLNLTKG
KTIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMEKMLNRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDV
SDLSGGQRTKILLAKLLLENPDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
VGDYNEFRRIYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKIDKIELTKEKPKPEFNFKQARA
SGKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANGLGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESN
YNTCIEEVWKEFPVFTQYEIRSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
RALKEYKGSILLVCHEKEFYEDIVTETWNCESWTTKIV
>Mature_517_residues
SILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKIQWAKDVRIGYMDQHLNLTKGK
TIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMEKMLNRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDVS
DLSGGQRTKILLAKLLLENPDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRYV
GDYNEFRRIYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKIDKIELTKEKPKPEFNFKQARAS
GKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANGLGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESNY
NTCIEEVWKEFPVFTQYEIRSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELKR
ALKEYKGSILLVCHEKEFYEDIVTETWNCESWTTKIV

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=511, Percent_Identity=28.5714285714286, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI27881506, Length=517, Percent_Identity=29.4003868471954, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI10947137, Length=517, Percent_Identity=29.4003868471954, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI69354671, Length=518, Percent_Identity=29.1505791505791, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI10947135, Length=518, Percent_Identity=29.1505791505791, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI90421313, Length=198, Percent_Identity=26.2626262626263, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787041, Length=510, Percent_Identity=34.3137254901961, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1789751, Length=489, Percent_Identity=29.038854805726, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1787182, Length=524, Percent_Identity=31.1068702290076, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI2367384, Length=500, Percent_Identity=29.2, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1789891, Length=278, Percent_Identity=25.5395683453237, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788165, Length=263, Percent_Identity=26.615969581749, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081782, Length=534, Percent_Identity=23.7827715355805, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788225, Length=191, Percent_Identity=29.3193717277487, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI48994943, Length=232, Percent_Identity=28.448275862069, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789991, Length=505, Percent_Identity=23.3663366336634, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI48994883, Length=258, Percent_Identity=24.8062015503876, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788506, Length=253, Percent_Identity=24.5059288537549, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788761, Length=178, Percent_Identity=28.6516853932584, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=523, Percent_Identity=28.2982791586998, Blast_Score=210, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17555318, Length=517, Percent_Identity=27.852998065764, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17553372, Length=531, Percent_Identity=28.8135593220339, Blast_Score=199, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6321121, Length=529, Percent_Identity=32.703213610586, Blast_Score=246, Evalue=5e-66,
Organism=Saccharomyces cerevisiae, GI6320874, Length=523, Percent_Identity=28.4894837476099, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6325030, Length=396, Percent_Identity=28.2828282828283, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324314, Length=388, Percent_Identity=25.2577319587629, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323278, Length=387, Percent_Identity=26.6149870801034, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24666836, Length=523, Percent_Identity=29.0630975143403, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24642252, Length=520, Percent_Identity=29.8076923076923, Blast_Score=204, Evalue=9e-53,
Organism=Drosophila melanogaster, GI18859989, Length=520, Percent_Identity=29.8076923076923, Blast_Score=204, Evalue=9e-53,
Organism=Drosophila melanogaster, GI24641342, Length=508, Percent_Identity=28.5433070866142, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24661270, Length=483, Percent_Identity=23.8095238095238, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355589, Length=483, Percent_Identity=23.8095238095238, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59592; Mature: 59461

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKI
CCEEEEEHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCE
QWAKDVRIGYMDQHLNLTKGKTIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMEKML
EEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDVSDLSGGQRTKILLAKLLLEN
HHHHHHHHHHCCCCEEEEECHHHHHHHCCCEEECCCCCCHHHCCCCCHHHHHHHHHHHCC
PDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHH
VGDYNEFRRIYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKID
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KIELTKEKPKPEFNFKQARASGKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANG
CEEECCCCCCCCCCHHHHCCCCCEEEEECCEEEECCCCCCCCCEEEECCCCEEEEEECCC
LGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESNYNTCIEEVWKEFPVFTQYEI
CCHHHHHHHHHHHCCCCCCCEEECCEEEECCCHHHHHCCHHHHHHHHHHHHCCCCCHHHH
RSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
HHHHHHCCCCHHHHCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
RALKEYKGSILLVCHEKEFYEDIVTETWNCESWTTKIV
HHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCEEECC
>Mature Secondary Structure 
SILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKI
CEEEEEHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCE
QWAKDVRIGYMDQHLNLTKGKTIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMEKML
EEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDVSDLSGGQRTKILLAKLLLEN
HHHHHHHHHHCCCCEEEEECHHHHHHHCCCEEECCCCCCHHHCCCCCHHHHHHHHHHHCC
PDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHH
VGDYNEFRRIYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKID
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KIELTKEKPKPEFNFKQARASGKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANG
CEEECCCCCCCCCCHHHHCCCCCEEEEECCEEEECCCCCCCCCEEEECCCCEEEEEECCC
LGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESNYNTCIEEVWKEFPVFTQYEI
CCHHHHHHHHHHHCCCCCCCEEECCEEEECCCHHHHHCCHHHHHHHHHHHHCCCCCHHHH
RSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
HHHHHHCCCCHHHHCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
RALKEYKGSILLVCHEKEFYEDIVTETWNCESWTTKIV
HHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]