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The map label for this gene is appB [H]

Identifier: 226948493

GI number: 226948493

Start: 1442814

End: 1443767

Strand: Reverse

Name: appB [H]

Synonym: CLM_1382

Alternate gene names: 226948493

Gene position: 1443767-1442814 (Counterclockwise)

Preceding gene: 226948494

Following gene: 226948492

Centisome position: 34.75

GC content: 28.83

Gene sequence:

>954_bases
TTGAGTAAATACATAAGAAAACGAATTGTAGAAGCAATTCCCATACTTATTTTCATTTCTATAATTTCTTTTTTACTAAT
AAAATTAGCACCGGGAGATCCTATTAGAGCCTTTATAAATCCCCAAATGAAGCCTTCTGATATAGCTAGAATTAGGCATA
ATTTAGGTCTTGATAAACCTACATATATACAATATATCTTATGGTTAAAAAATGTATTAAAAGGTGATTTAGGTTATTCT
TTAATAAACTCTAGACCAATTTCTACACAAATAATAGAAAGACTTCCTGCTACCTTACTTCTTATGGGTTCCTCTTTATT
AATATCTTTAGTTTTAGGTATAATTTTGGGAGTTATTTCTGCAGTTAATAAAAATAAACTTATAGATAATATCCTTTCAG
TAATCTCTTATATAGGTATATCTATACCTAGTTTTTGGTTTGCTATGATACTAATATACATTTTTTCTGTTAACCTTAAA
TTGCTACCCAGTGTTGGTATGCATACTATAGGTGTAGATTCTAGATTAGATGTATTAAAACATCTTATTTTACCTTGCAC
AGTATTAAGTTTTGGAAACATATCAGTTATTACTAGATATATAAGATCCAATGTAATCTCTGAACTGTCTGAAGATTATG
TTATGATTGCCTATGCCAAAGGATTATCTAAAAAAAGAATATTATATAAACACGTCTTAAAGAATGCTCTTTTGCCTATT
ATCACCATATTAGGCATGTCCTTACCTAATTTAGTAGCTGGTGCTTTTATAACTGAAACTATTTTTGGATGGCCTGGTAT
GGGTAGACTAGGTATAAAAGCTATATTTGGTTTTGACTATCCTCTTATTATGGCTATAACTATGTTAACTTCTGTTTTAC
TTATAATAGGTAACCTTTTAGCAGACATATGTTATAGCTTAATAGATCCTAGAATTAAAGAGTTAGGTAGGTGA

Upstream 100 bases:

>100_bases
TATTTTTTATTTAATATATTAAAGCACTAAAATTTAGCTAACAATTATTATTTAATCTTTAAATTATATAATAAAAATAA
TTAAGAAAGGTAGGATATAT

Downstream 100 bases:

>100_bases
TAAATTTGTTTTTAAATGAAAGGCTTAAACTAAATTTAAAAATACAATTTAAAGAAAATAAATTAGGATATATATCTTTA
TCTATAATTTTAATATTAGT

Product: putative oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSKYIRKRIVEAIPILIFISIISFLLIKLAPGDPIRAFINPQMKPSDIARIRHNLGLDKPTYIQYILWLKNVLKGDLGYS
LINSRPISTQIIERLPATLLLMGSSLLISLVLGIILGVISAVNKNKLIDNILSVISYIGISIPSFWFAMILIYIFSVNLK
LLPSVGMHTIGVDSRLDVLKHLILPCTVLSFGNISVITRYIRSNVISELSEDYVMIAYAKGLSKKRILYKHVLKNALLPI
ITILGMSLPNLVAGAFITETIFGWPGMGRLGIKAIFGFDYPLIMAITMLTSVLLIIGNLLADICYSLIDPRIKELGR

Sequences:

>Translated_317_residues
MSKYIRKRIVEAIPILIFISIISFLLIKLAPGDPIRAFINPQMKPSDIARIRHNLGLDKPTYIQYILWLKNVLKGDLGYS
LINSRPISTQIIERLPATLLLMGSSLLISLVLGIILGVISAVNKNKLIDNILSVISYIGISIPSFWFAMILIYIFSVNLK
LLPSVGMHTIGVDSRLDVLKHLILPCTVLSFGNISVITRYIRSNVISELSEDYVMIAYAKGLSKKRILYKHVLKNALLPI
ITILGMSLPNLVAGAFITETIFGWPGMGRLGIKAIFGFDYPLIMAITMLTSVLLIIGNLLADICYSLIDPRIKELGR
>Mature_316_residues
SKYIRKRIVEAIPILIFISIISFLLIKLAPGDPIRAFINPQMKPSDIARIRHNLGLDKPTYIQYILWLKNVLKGDLGYSL
INSRPISTQIIERLPATLLLMGSSLLISLVLGIILGVISAVNKNKLIDNILSVISYIGISIPSFWFAMILIYIFSVNLKL
LPSVGMHTIGVDSRLDVLKHLILPCTVLSFGNISVITRYIRSNVISELSEDYVMIAYAKGLSKKRILYKHVLKNALLPII
TILGMSLPNLVAGAFITETIFGWPGMGRLGIKAIFGFDYPLIMAITMLTSVLLIIGNLLADICYSLIDPRIKELGR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=313, Percent_Identity=36.4217252396166, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789888, Length=317, Percent_Identity=35.0157728706625, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=34.1246290801187, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI1787761, Length=332, Percent_Identity=35.5421686746988, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=33.1210191082803, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=32.8358208955224, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788504, Length=364, Percent_Identity=29.3956043956044, Blast_Score=147, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35245; Mature: 35114

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYIRKRIVEAIPILIFISIISFLLIKLAPGDPIRAFINPQMKPSDIARIRHNLGLDKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCH
TYIQYILWLKNVLKGDLGYSLINSRPISTQIIERLPATLLLMGSSLLISLVLGIILGVIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNKNKLIDNILSVISYIGISIPSFWFAMILIYIFSVNLKLLPSVGMHTIGVDSRLDVLK
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHCCCCHHHHHHH
HLILPCTVLSFGNISVITRYIRSNVISELSEDYVMIAYAKGLSKKRILYKHVLKNALLPI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHH
ITILGMSLPNLVAGAFITETIFGWPGMGRLGIKAIFGFDYPLIMAITMLTSVLLIIGNLL
HHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ADICYSLIDPRIKELGR
HHHHHHHHCHHHHHHCC
>Mature Secondary Structure 
SKYIRKRIVEAIPILIFISIISFLLIKLAPGDPIRAFINPQMKPSDIARIRHNLGLDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCH
TYIQYILWLKNVLKGDLGYSLINSRPISTQIIERLPATLLLMGSSLLISLVLGIILGVIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNKNKLIDNILSVISYIGISIPSFWFAMILIYIFSVNLKLLPSVGMHTIGVDSRLDVLK
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHCCCCHHHHHHH
HLILPCTVLSFGNISVITRYIRSNVISELSEDYVMIAYAKGLSKKRILYKHVLKNALLPI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHH
ITILGMSLPNLVAGAFITETIFGWPGMGRLGIKAIFGFDYPLIMAITMLTSVLLIIGNLL
HHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ADICYSLIDPRIKELGR
HHHHHHHHCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]