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The map label for this gene is appC [H]

Identifier: 226948492

GI number: 226948492

Start: 1441960

End: 1442808

Strand: Reverse

Name: appC [H]

Synonym: CLM_1381

Alternate gene names: 226948492

Gene position: 1442808-1441960 (Counterclockwise)

Preceding gene: 226948493

Following gene: 226948491

Centisome position: 34.72

GC content: 30.62

Gene sequence:

>849_bases
TTGTTTTTAAATGAAAGGCTTAAACTAAATTTAAAAATACAATTTAAAGAAAATAAATTAGGATATATATCTTTATCTAT
AATTTTAATATTAGTTCTTTTCTCAACCTTTTCTTTCTTGTCTCCTTATGATCCTAACAAAATAGATCTATCCAACAAAT
TAGTCAATCCTAGTTTAAAACATTTATTTGGCACAGATGAAATGGGTAGGGATTATTTTACCAGATCTTTATACGGCGGA
AGAGCCTCTCTAATGGTAGGTTTTATATCCATGATTATATCCACAGCCCTAGGAACTATTATAGGAACCTTTAGTGGCTA
TATAGGTGGCAAGATAGATAATATATTAATGAGAATCATAGATATATTAATGTGTATTCCAACCTTTTTTCTCATCCTTA
TAATTAATGCCTATTTAAAACCAGGTATAGAAAACATAATTATTATCATTGGATTGTTTGGATGGATGGACATTGCTAGA
ATAGTTAGAGCCCAAACCCTTTCATTAAAAGAAAGAGAGTATGTACTATGTTCAAAGGCTTTAGGCGCCTCTAATAGAAG
AATTGTTTTTAAGCATATAATACCAAACGTTATCCCCTCTGTAATGGTAGCCTCTACCATAAATATTGCATCTGCTATTC
TTACAGAATCCTCCCTTAGTTTTTTAGGATTAGGAGTTAGAGCTCCTAATTCCTCTTGGGGAAGTATGCTACAAAATGCT
CAAGGTTTTATTTCCTCAGCACCCTATTTAGCTATATTTCCTGGACTTTTTATACTTTTTACAGTTTTAAACTTTAATAT
ATTAGGAGATATTTTTGCCACTGCATTTGATCCTAAAGCTAATAAATAA

Upstream 100 bases:

>100_bases
CTATGTTAACTTCTGTTTTACTTATAATAGGTAACCTTTTAGCAGACATATGTTATAGCTTAATAGATCCTAGAATTAAA
GAGTTAGGTAGGTGATAAAT

Downstream 100 bases:

>100_bases
TGCTCCTTTAAAAATAAACCATTATATACGATAAAAGTACTGTATATATTTAATGGTTTATTTTCATTTATATTAACTAT
ACAGTAAATCGTTGACAAAA

Product: putative oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MFLNERLKLNLKIQFKENKLGYISLSIILILVLFSTFSFLSPYDPNKIDLSNKLVNPSLKHLFGTDEMGRDYFTRSLYGG
RASLMVGFISMIISTALGTIIGTFSGYIGGKIDNILMRIIDILMCIPTFFLILIINAYLKPGIENIIIIIGLFGWMDIAR
IVRAQTLSLKEREYVLCSKALGASNRRIVFKHIIPNVIPSVMVASTINIASAILTESSLSFLGLGVRAPNSSWGSMLQNA
QGFISSAPYLAIFPGLFILFTVLNFNILGDIFATAFDPKANK

Sequences:

>Translated_282_residues
MFLNERLKLNLKIQFKENKLGYISLSIILILVLFSTFSFLSPYDPNKIDLSNKLVNPSLKHLFGTDEMGRDYFTRSLYGG
RASLMVGFISMIISTALGTIIGTFSGYIGGKIDNILMRIIDILMCIPTFFLILIINAYLKPGIENIIIIIGLFGWMDIAR
IVRAQTLSLKEREYVLCSKALGASNRRIVFKHIIPNVIPSVMVASTINIASAILTESSLSFLGLGVRAPNSSWGSMLQNA
QGFISSAPYLAIFPGLFILFTVLNFNILGDIFATAFDPKANK
>Mature_282_residues
MFLNERLKLNLKIQFKENKLGYISLSIILILVLFSTFSFLSPYDPNKIDLSNKLVNPSLKHLFGTDEMGRDYFTRSLYGG
RASLMVGFISMIISTALGTIIGTFSGYIGGKIDNILMRIIDILMCIPTFFLILIINAYLKPGIENIIIIIGLFGWMDIAR
IVRAQTLSLKEREYVLCSKALGASNRRIVFKHIIPNVIPSVMVASTINIASAILTESSLSFLGLGVRAPNSSWGSMLQNA
QGFISSAPYLAIFPGLFILFTVLNFNILGDIFATAFDPKANK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=268, Percent_Identity=38.0597014925373, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787760, Length=268, Percent_Identity=36.9402985074627, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=38.5245901639344, Blast_Score=187, Evalue=8e-49,
Organism=Escherichia coli, GI1787498, Length=273, Percent_Identity=38.0952380952381, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789964, Length=276, Percent_Identity=36.231884057971, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788505, Length=225, Percent_Identity=34.2222222222222, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787549, Length=238, Percent_Identity=30.2521008403361, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31222; Mature: 31222

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLNERLKLNLKIQFKENKLGYISLSIILILVLFSTFSFLSPYDPNKIDLSNKLVNPSLK
CCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHH
HLFGTDEMGRDYFTRSLYGGRASLMVGFISMIISTALGTIIGTFSGYIGGKIDNILMRII
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DILMCIPTFFLILIINAYLKPGIENIIIIIGLFGWMDIARIVRAQTLSLKEREYVLCSKA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGASNRRIVFKHIIPNVIPSVMVASTINIASAILTESSLSFLGLGVRAPNSSWGSMLQNA
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
QGFISSAPYLAIFPGLFILFTVLNFNILGDIFATAFDPKANK
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFLNERLKLNLKIQFKENKLGYISLSIILILVLFSTFSFLSPYDPNKIDLSNKLVNPSLK
CCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHH
HLFGTDEMGRDYFTRSLYGGRASLMVGFISMIISTALGTIIGTFSGYIGGKIDNILMRII
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DILMCIPTFFLILIINAYLKPGIENIIIIIGLFGWMDIARIVRAQTLSLKEREYVLCSKA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGASNRRIVFKHIIPNVIPSVMVASTINIASAILTESSLSFLGLGVRAPNSSWGSMLQNA
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
QGFISSAPYLAIFPGLFILFTVLNFNILGDIFATAFDPKANK
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]