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The map label for this gene is trxB [H]

Identifier: 226948347

GI number: 226948347

Start: 1280522

End: 1281778

Strand: Direct

Name: trxB [H]

Synonym: CLM_1229

Alternate gene names: 226948347

Gene position: 1280522-1281778 (Clockwise)

Preceding gene: 226948346

Following gene: 226948348

Centisome position: 30.82

GC content: 31.34

Gene sequence:

>1257_bases
ATGCAACAATATGATGTAGTTATAATTGGTGGAGGCCCAGCAGGTCTTGCCGCTGCTATAAAAGCTAAAGAAGAAGGCGT
AGACAGTATATTAATATTAGAGAGAGATAAAAGATTAGGTGGAATATTAAATCAATGTATTCATAATGGATTTGGACTTC
ATACTTTTAAAGAAGAACTTACAGGACCAGAATATGCTCAAAGATTTGTAGATAAAGTAAAAGAAATGAAAATACCATAC
AAATTAAATACTATGGTAATTGATATGAACAAAGATAAAATAATAACAGCAGTTAATGAGGAAGATGGATTAATAGAAGT
GCAAGCTAAATCTATAGTACTAGCTATGGGTTGTAGAGAAAGATCAAGAGGAGCTATAAATATTCCAGGCACAAGATGTT
CAGGGATATATTCAGCAGGAACAGCACAAAAATTTGTAAATATAGAGGGTGAAATGCCAGGAAAGGAAGTAGTTATTTTA
GGGTCTGGAGATATAGGACTTATAATGGCTAGAAGAATGACTTTAGAAGGATCTAAAGTAAAGGCAGTAGTAGAACTTAT
GCCTTATTCTGGAGGATTAAAAAGAAATATAGTTCAATGTTTGGATGACTTCGGTATTCCTTTAAAGCTAGCTCATACTA
TAACTAAAATAGAAGGAAAAGAAAGATTAGAAGCTGTTACTATAGCAAAGGTAGATGAAAAACTAAAACCTATAAAAGGA
ACAGAAGAATATATAAAATGTGATACATTACTTTTATCAGTTGGATTGCTTCCAGAAAATGATCTATCAAGAAAAGCAGA
TGTTAAGTTAGGAGTAACTGGTGGTCCAGAAGTAGATGAAACAATGCAAACTAATATAGATGGAGTGTTTGCTTGTGGTA
ATGTTCTTCACGTACATGATTTAGTAGACTTTGTAACAGAGGAAAGTTATAATGCAGGTAAAAATGCTGCAGATTATGTA
AAGGGTAAAAAAGTAGAAGGTGAAAAAATAGAACTAGTTGCAGAAAATGGTGTAGGATATACTGTACCAAAATCAATACA
CAAAAGCAATATAGAAAATACAGTAGATGTTAGATTTAGAGTAAGAAATGTGTTTAAAGATAGTTTCATATCTGTATATT
TTGATGATGAAAGAGTAGTTCATAGAAAGAAAAAAGTTATAGCTCCAGGTGAGATGGAAACAGTAAAATTAACTAAAGAT
ATGTTTGAAAAACATTTAGATTGCAAAAAAATTACTGTTAAAGTGGAAGGTGAATAA

Upstream 100 bases:

>100_bases
AATGAAGTTACTAAGTTTGGCGGAAATTCAAAAATATTATATTAGAAAACTAATTTAAATTAATGAGGTAATTTAAAGCA
AATGCATTGGAGGGCGTAGT

Downstream 100 bases:

>100_bases
TTATGGCTGTAAGAGAATTAATATGTATAGGATGTCCATTGGGATGTAATCTAGAAGTAGAAATTGAAGATAAAGAAGTA
AAGTCAGTTAAGGGAAATAC

Product: pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MQQYDVVIIGGGPAGLAAAIKAKEEGVDSILILERDKRLGGILNQCIHNGFGLHTFKEELTGPEYAQRFVDKVKEMKIPY
KLNTMVIDMNKDKIITAVNEEDGLIEVQAKSIVLAMGCRERSRGAINIPGTRCSGIYSAGTAQKFVNIEGEMPGKEVVIL
GSGDIGLIMARRMTLEGSKVKAVVELMPYSGGLKRNIVQCLDDFGIPLKLAHTITKIEGKERLEAVTIAKVDEKLKPIKG
TEEYIKCDTLLLSVGLLPENDLSRKADVKLGVTGGPEVDETMQTNIDGVFACGNVLHVHDLVDFVTEESYNAGKNAADYV
KGKKVEGEKIELVAENGVGYTVPKSIHKSNIENTVDVRFRVRNVFKDSFISVYFDDERVVHRKKKVIAPGEMETVKLTKD
MFEKHLDCKKITVKVEGE

Sequences:

>Translated_418_residues
MQQYDVVIIGGGPAGLAAAIKAKEEGVDSILILERDKRLGGILNQCIHNGFGLHTFKEELTGPEYAQRFVDKVKEMKIPY
KLNTMVIDMNKDKIITAVNEEDGLIEVQAKSIVLAMGCRERSRGAINIPGTRCSGIYSAGTAQKFVNIEGEMPGKEVVIL
GSGDIGLIMARRMTLEGSKVKAVVELMPYSGGLKRNIVQCLDDFGIPLKLAHTITKIEGKERLEAVTIAKVDEKLKPIKG
TEEYIKCDTLLLSVGLLPENDLSRKADVKLGVTGGPEVDETMQTNIDGVFACGNVLHVHDLVDFVTEESYNAGKNAADYV
KGKKVEGEKIELVAENGVGYTVPKSIHKSNIENTVDVRFRVRNVFKDSFISVYFDDERVVHRKKKVIAPGEMETVKLTKD
MFEKHLDCKKITVKVEGE
>Mature_418_residues
MQQYDVVIIGGGPAGLAAAIKAKEEGVDSILILERDKRLGGILNQCIHNGFGLHTFKEELTGPEYAQRFVDKVKEMKIPY
KLNTMVIDMNKDKIITAVNEEDGLIEVQAKSIVLAMGCRERSRGAINIPGTRCSGIYSAGTAQKFVNIEGEMPGKEVVIL
GSGDIGLIMARRMTLEGSKVKAVVELMPYSGGLKRNIVQCLDDFGIPLKLAHTITKIEGKERLEAVTIAKVDEKLKPIKG
TEEYIKCDTLLLSVGLLPENDLSRKADVKLGVTGGPEVDETMQTNIDGVFACGNVLHVHDLVDFVTEESYNAGKNAADYV
KGKKVEGEKIELVAENGVGYTVPKSIHKSNIENTVDVRFRVRNVFKDSFISVYFDDERVVHRKKKVIAPGEMETVKLTKD
MFEKHLDCKKITVKVEGE

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 46039; Mature: 46039

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQYDVVIIGGGPAGLAAAIKAKEEGVDSILILERDKRLGGILNQCIHNGFGLHTFKEEL
CCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHC
TGPEYAQRFVDKVKEMKIPYKLNTMVIDMNKDKIITAVNEEDGLIEVQAKSIVLAMGCRE
CCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCCCEEEEEECEEEEEECCCC
RSRGAINIPGTRCSGIYSAGTAQKFVNIEGEMPGKEVVILGSGDIGLIMARRMTLEGSKV
CCCCEEECCCCCCCCEECCCCCEEEEEECCCCCCCEEEEEECCCEEEEEEEEEECCCCCE
KAVVELMPYSGGLKRNIVQCLDDFGIPLKLAHTITKIEGKERLEAVTIAKVDEKLKPIKG
EEEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHHHCCCHHHHHEEHHHHHHHHHCCCCC
TEEYIKCDTLLLSVGLLPENDLSRKADVKLGVTGGPEVDETMQTNIDGVFACGNVLHVHD
CHHHHHHHHHEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCCEEEECCCEEHHHH
LVDFVTEESYNAGKNAADYVKGKKVEGEKIELVAENGVGYTVPKSIHKSNIENTVDVRFR
HHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCEEEEEHH
VRNVFKDSFISVYFDDERVVHRKKKVIAPGEMETVKLTKDMFEKHLDCKKITVKVEGE
HHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCEEEEEEEECC
>Mature Secondary Structure
MQQYDVVIIGGGPAGLAAAIKAKEEGVDSILILERDKRLGGILNQCIHNGFGLHTFKEEL
CCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHC
TGPEYAQRFVDKVKEMKIPYKLNTMVIDMNKDKIITAVNEEDGLIEVQAKSIVLAMGCRE
CCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCCCEEEEEECEEEEEECCCC
RSRGAINIPGTRCSGIYSAGTAQKFVNIEGEMPGKEVVILGSGDIGLIMARRMTLEGSKV
CCCCEEECCCCCCCCEECCCCCEEEEEECCCCCCCEEEEEECCCEEEEEEEEEECCCCCE
KAVVELMPYSGGLKRNIVQCLDDFGIPLKLAHTITKIEGKERLEAVTIAKVDEKLKPIKG
EEEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHHHCCCHHHHHEEHHHHHHHHHCCCCC
TEEYIKCDTLLLSVGLLPENDLSRKADVKLGVTGGPEVDETMQTNIDGVFACGNVLHVHD
CHHHHHHHHHEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCCEEEECCCEEHHHH
LVDFVTEESYNAGKNAADYVKGKKVEGEKIELVAENGVGYTVPKSIHKSNIENTVDVRFR
HHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCEEEEEHH
VRNVFKDSFISVYFDDERVVHRKKKVIAPGEMETVKLTKDMFEKHLDCKKITVKVEGE
HHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]