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The map label for this gene is yhdR [H]

Identifier: 226948289

GI number: 226948289

Start: 1211912

End: 1213096

Strand: Reverse

Name: yhdR [H]

Synonym: CLM_1169

Alternate gene names: 226948289

Gene position: 1213096-1211912 (Counterclockwise)

Preceding gene: 226948290

Following gene: 226948272

Centisome position: 29.19

GC content: 31.05

Gene sequence:

>1185_bases
ATGATTTCAAATGAAATGCTTAATCTTGGAAAAAAACGCTCTATAATACGTGATATCTTTGAATACGGAGCAACTAGAAA
AAAAGAAATAGGCGCAGAAAATGTATACGATTTTAGCTTAGGAAATCCTAGTATTCCAGCACCAGATTGTGTAAATGAAG
CTATTAAAGAGTTATTAGAAAAAGAAGATTCTATACGTTTGCACAGCTACACATCAGCGCAAGGAGATCTTAGTGTTAGA
AAAACAATTTCAGATTCTATTAATAATAAATATTCTACAAACTTGAGCCCTGATAACATATATATGACAGTTGGAGCAGC
AGCTTCACTTAGTATATCTTTAAAGGCATTAGCTGTTCCAGGAGATGAATTTATTGTTTTCACTCCATTTTTTCCTGAAT
ACCGTGTATTTATTCAAAATGCTGGTGGAACACCTGTTGTAGTTAAATCCAATGAAGATGATTTTCAAATTGATATAAAT
AATTTAATTGAAGCAATAACACCTAAAACTAAAGCTGTTCTTATTAATTCTCCTAATAATCCTTCTGGGGTTATTATATC
TGAGGAAAGTATTAAATCACTTTGTAAGGTACTTGAAAAAAAATCAAATGAATATGGTCATCCAATATATTTAATTGCAG
ATGAACCTTATAGAGAATTAGTTTATGATGATATTGAAGTTCCTTATTTAACAAAATACTACGCTAATACATTCGTTTGC
TATTCATTTAGTAAATCCCTTTCATTACCAGGAGAAAGAATAGGATATATAGTTGTATCTAATGAAATGGAAAACTGGCA
AGACGTATATGCTGCAGTATGTGGAGCAGGTAGATCATTAGGATATGTATGTGCTCCAAGTTTATTCCAAAGAGTAATTG
CAAAATGTATTGGCCAAACTGCTGATATCTCAGTTTATAAGAAAAATAGAGATATATTATATAATGGACTAACTAAATTA
GGTTATACATGTGTAAAACCAGACGGTGCATTTTATCTATTTGTTAAATCAATGGAACCAGATGCTTATGCTTTCTATGA
AAAAGCTAAAAAGCACGAATTATTAATAGTTCCTGCTGATGATTTTGGAGCTCCAGGCTATGTAAGAATCTCTTATTGTG
TTACAACTGAACAAATAGAGAACTCTATGCCTGCTTTTGAAAAACTTGCAAAAGAGTATAAATAG

Upstream 100 bases:

>100_bases
TAGATGATGAAAAATATTTAAAAATTTAAGGAACTAATATCTTATAAAAGATGTTAAAGATAATAAGTTCAAACTATATT
GTTTTTAGGGGGAAATTAAA

Downstream 100 bases:

>100_bases
TAAATAAGAATTATATAAAAATAGTACAACCGCTAATTAACTATTAATATTTAATTAGCGGTTTTTAATATTATTAATTT
AAATCATGAGCTATATTTAG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MISNEMLNLGKKRSIIRDIFEYGATRKKEIGAENVYDFSLGNPSIPAPDCVNEAIKELLEKEDSIRLHSYTSAQGDLSVR
KTISDSINNKYSTNLSPDNIYMTVGAAASLSISLKALAVPGDEFIVFTPFFPEYRVFIQNAGGTPVVVKSNEDDFQIDIN
NLIEAITPKTKAVLINSPNNPSGVIISEESIKSLCKVLEKKSNEYGHPIYLIADEPYRELVYDDIEVPYLTKYYANTFVC
YSFSKSLSLPGERIGYIVVSNEMENWQDVYAAVCGAGRSLGYVCAPSLFQRVIAKCIGQTADISVYKKNRDILYNGLTKL
GYTCVKPDGAFYLFVKSMEPDAYAFYEKAKKHELLIVPADDFGAPGYVRISYCVTTEQIENSMPAFEKLAKEYK

Sequences:

>Translated_394_residues
MISNEMLNLGKKRSIIRDIFEYGATRKKEIGAENVYDFSLGNPSIPAPDCVNEAIKELLEKEDSIRLHSYTSAQGDLSVR
KTISDSINNKYSTNLSPDNIYMTVGAAASLSISLKALAVPGDEFIVFTPFFPEYRVFIQNAGGTPVVVKSNEDDFQIDIN
NLIEAITPKTKAVLINSPNNPSGVIISEESIKSLCKVLEKKSNEYGHPIYLIADEPYRELVYDDIEVPYLTKYYANTFVC
YSFSKSLSLPGERIGYIVVSNEMENWQDVYAAVCGAGRSLGYVCAPSLFQRVIAKCIGQTADISVYKKNRDILYNGLTKL
GYTCVKPDGAFYLFVKSMEPDAYAFYEKAKKHELLIVPADDFGAPGYVRISYCVTTEQIENSMPAFEKLAKEYK
>Mature_394_residues
MISNEMLNLGKKRSIIRDIFEYGATRKKEIGAENVYDFSLGNPSIPAPDCVNEAIKELLEKEDSIRLHSYTSAQGDLSVR
KTISDSINNKYSTNLSPDNIYMTVGAAASLSISLKALAVPGDEFIVFTPFFPEYRVFIQNAGGTPVVVKSNEDDFQIDIN
NLIEAITPKTKAVLINSPNNPSGVIISEESIKSLCKVLEKKSNEYGHPIYLIADEPYRELVYDDIEVPYLTKYYANTFVC
YSFSKSLSLPGERIGYIVVSNEMENWQDVYAAVCGAGRSLGYVCAPSLFQRVIAKCIGQTADISVYKKNRDILYNGLTKL
GYTCVKPDGAFYLFVKSMEPDAYAFYEKAKKHELLIVPADDFGAPGYVRISYCVTTEQIENSMPAFEKLAKEYK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=329, Percent_Identity=24.0121580547112, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI169881279, Length=329, Percent_Identity=24.0121580547112, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4507369, Length=373, Percent_Identity=24.6648793565684, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI56713254, Length=369, Percent_Identity=25.2032520325203, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI56713256, Length=368, Percent_Identity=24.7282608695652, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI169881281, Length=236, Percent_Identity=23.3050847457627, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788627, Length=391, Percent_Identity=23.5294117647059, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788722, Length=384, Percent_Identity=23.4375, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786816, Length=346, Percent_Identity=22.5433526011561, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=25.4054054054054, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=328, Percent_Identity=27.4390243902439, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=234, Percent_Identity=27.7777777777778, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=234, Percent_Identity=27.7777777777778, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=367, Percent_Identity=26.9754768392371, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6320317, Length=364, Percent_Identity=24.1758241758242, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=25.7294429708223, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573069, Length=396, Percent_Identity=24.4949494949495, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24646114, Length=396, Percent_Identity=24.4949494949495, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28573067, Length=396, Percent_Identity=24.4949494949495, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28573065, Length=396, Percent_Identity=24.4949494949495, Blast_Score=88, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43980; Mature: 43980

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNEMLNLGKKRSIIRDIFEYGATRKKEIGAENVYDFSLGNPSIPAPDCVNEAIKELLE
CCCCHHHHCCHHHHHHHHHHHHCCCCCHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHC
KEDSIRLHSYTSAQGDLSVRKTISDSINNKYSTNLSPDNIYMTVGAAASLSISLKALAVP
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCEEEEEECCCEEEEEEEEEEEEC
GDEFIVFTPFFPEYRVFIQNAGGTPVVVKSNEDDFQIDINNLIEAITPKTKAVLINSPNN
CCCEEEECCCCCCEEEEEECCCCCEEEEECCCCCEEEEHHHHHHHHCCCCEEEEEECCCC
PSGVIISEESIKSLCKVLEKKSNEYGHPIYLIADEPYRELVYDDIEVPYLTKYYANTFVC
CCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCCCCCHHHHHHCEEEE
YSFSKSLSLPGERIGYIVVSNEMENWQDVYAAVCGAGRSLGYVCAPSLFQRVIAKCIGQT
EEECCCCCCCCHHEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
ADISVYKKNRDILYNGLTKLGYTCVKPDGAFYLFVKSMEPDAYAFYEKAKKHELLIVPAD
CCEEEEECCCCCEECCHHHHCCEEECCCCEEEEEEEECCCCHHHHHHHCCCCEEEEEECC
DFGAPGYVRISYCVTTEQIENSMPAFEKLAKEYK
CCCCCCEEEEEEEEEHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MISNEMLNLGKKRSIIRDIFEYGATRKKEIGAENVYDFSLGNPSIPAPDCVNEAIKELLE
CCCCHHHHCCHHHHHHHHHHHHCCCCCHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHC
KEDSIRLHSYTSAQGDLSVRKTISDSINNKYSTNLSPDNIYMTVGAAASLSISLKALAVP
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCEEEEEECCCEEEEEEEEEEEEC
GDEFIVFTPFFPEYRVFIQNAGGTPVVVKSNEDDFQIDINNLIEAITPKTKAVLINSPNN
CCCEEEECCCCCCEEEEEECCCCCEEEEECCCCCEEEEHHHHHHHHCCCCEEEEEECCCC
PSGVIISEESIKSLCKVLEKKSNEYGHPIYLIADEPYRELVYDDIEVPYLTKYYANTFVC
CCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCCCCCHHHHHHCEEEE
YSFSKSLSLPGERIGYIVVSNEMENWQDVYAAVCGAGRSLGYVCAPSLFQRVIAKCIGQT
EEECCCCCCCCHHEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
ADISVYKKNRDILYNGLTKLGYTCVKPDGAFYLFVKSMEPDAYAFYEKAKKHELLIVPAD
CCEEEEECCCCCEECCHHHHCCEEECCCCEEEEEEEECCCCHHHHHHHCCCCEEEEEECC
DFGAPGYVRISYCVTTEQIENSMPAFEKLAKEYK
CCCCCCEEEEEEEEEHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]