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The map label for this gene is spr [H]

Identifier: 226948264

GI number: 226948264

Start: 1180489

End: 1181457

Strand: Direct

Name: spr [H]

Synonym: CLM_1144

Alternate gene names: 226948264

Gene position: 1180489-1181457 (Clockwise)

Preceding gene: 226948263

Following gene: 226948266

Centisome position: 28.41

GC content: 34.26

Gene sequence:

>969_bases
ATGAAAAAAAAGACAACCATATTAAGTATCTTTCTAGCTGTTTTTATGGCTTTAGCTATGAATGTAGGGCAAGTTAAAGC
TGCAGCAACTGGACAAGATATAGTAAACTATGCTAAACAATTTCAAGGGGTTCCATATGTGTGGGGAGGTACATCACCAA
GTGGCTTTGATTGTTCAGGATTTGTACAATATGTATATAGAAATGCTGCAGGCATAGAATTGCCAAGGGATACATATGGA
CAGATTACAAAAGGTACTCCAGTATCACAAAGTAATTTACAACCAGGAGATTTAGTATTTCCACATACAGGCCATGTAGG
TATATATGTTGGAAATGGACAAATAATACATTCACCTCAAACAGGTGATGTGGTAAAAATATCGCCAATATGGAAGTTTT
ATGCAGCAAGGAGAATTATAAATAAACCTCAATCCTATATTAATATAGATGGCGGAGGAACATTAGCTTGCAATGGTACT
TCAGGAATGAACTTGATAATAAGAGATTATTCTAGTGATGTAGTTAGAGCATTTGGATGGGTAGATAGTGATCCGAGTTG
TTCTTGGGCATTTGATGTCACTCCACCAAATAGTAATTATACAAAATTATATAAGGGAACAAATAAAGTTATAAATTTAA
GAAATAATGGAAGCCCATTTACACCAGGTGGAAATTATAAACTAACAGTTAAAGGATATGATAAAAATGGAAAAGTTGTA
TGCGAAAGAAGTATAAATCTAAAAGTTCCAAATGGAATAGCAAATTCATCAGCTAAACCAATTTTCCCAGGATCCTATAC
CGTAACGGCTCAAACAGTGGCAAGAGAATATCCAAGATCAAATGGGGCAGTAACTGGAAACTTAAAAAAAGGTCAAGAAG
TAGGTGTATTTGCTGAATATGGAAATTGGTATTTAGTTGCAAGAGGAACACCTCAATGGGTAGAGAAACAATATTTAACA
AATAAATAG

Upstream 100 bases:

>100_bases
AAAAGATGTAGGATAAAAAAAGAAGGAATTGAATTAATTGTAAAGAATATAAATATTATGGTAAAAATATAAAATAAATA
GACAAATAGGAGGAAGCAAC

Downstream 100 bases:

>100_bases
TTTAAATGCAGCCCTTAATCGGGCTGCTTATTTTTAAATATTTAAAGGAATCTTTTAACATTTGCAGAGTATTAAATATA
ACGGCTTACCAATAGGCTAA

Product: NlpC/P60 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKKKTTILSIFLAVFMALAMNVGQVKAAATGQDIVNYAKQFQGVPYVWGGTSPSGFDCSGFVQYVYRNAAGIELPRDTYG
QITKGTPVSQSNLQPGDLVFPHTGHVGIYVGNGQIIHSPQTGDVVKISPIWKFYAARRIINKPQSYINIDGGGTLACNGT
SGMNLIIRDYSSDVVRAFGWVDSDPSCSWAFDVTPPNSNYTKLYKGTNKVINLRNNGSPFTPGGNYKLTVKGYDKNGKVV
CERSINLKVPNGIANSSAKPIFPGSYTVTAQTVAREYPRSNGAVTGNLKKGQEVGVFAEYGNWYLVARGTPQWVEKQYLT
NK

Sequences:

>Translated_322_residues
MKKKTTILSIFLAVFMALAMNVGQVKAAATGQDIVNYAKQFQGVPYVWGGTSPSGFDCSGFVQYVYRNAAGIELPRDTYG
QITKGTPVSQSNLQPGDLVFPHTGHVGIYVGNGQIIHSPQTGDVVKISPIWKFYAARRIINKPQSYINIDGGGTLACNGT
SGMNLIIRDYSSDVVRAFGWVDSDPSCSWAFDVTPPNSNYTKLYKGTNKVINLRNNGSPFTPGGNYKLTVKGYDKNGKVV
CERSINLKVPNGIANSSAKPIFPGSYTVTAQTVAREYPRSNGAVTGNLKKGQEVGVFAEYGNWYLVARGTPQWVEKQYLT
NK
>Mature_322_residues
MKKKTTILSIFLAVFMALAMNVGQVKAAATGQDIVNYAKQFQGVPYVWGGTSPSGFDCSGFVQYVYRNAAGIELPRDTYG
QITKGTPVSQSNLQPGDLVFPHTGHVGIYVGNGQIIHSPQTGDVVKISPIWKFYAARRIINKPQSYINIDGGGTLACNGT
SGMNLIIRDYSSDVVRAFGWVDSDPSCSWAFDVTPPNSNYTKLYKGTNKVINLRNNGSPFTPGGNYKLTVKGYDKNGKVV
CERSINLKVPNGIANSSAKPIFPGSYTVTAQTVAREYPRSNGAVTGNLKKGQEVGVFAEYGNWYLVARGTPQWVEKQYLT
NK

Specific function: Unknown

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpC/p60 family [H]

Homologues:

Organism=Escherichia coli, GI1788501, Length=118, Percent_Identity=43.2203389830509, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786421, Length=123, Percent_Identity=40.650406504065, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787944, Length=121, Percent_Identity=40.495867768595, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788001, Length=112, Percent_Identity=41.0714285714286, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064 [H]

Pfam domain/function: PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 35008; Mature: 35008

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKTTILSIFLAVFMALAMNVGQVKAAATGQDIVNYAKQFQGVPYVWGGTSPSGFDCSG
CCCHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHH
FVQYVYRNAAGIELPRDTYGQITKGTPVSQSNLQPGDLVFPHTGHVGIYVGNGQIIHSPQ
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEECCCEEEECCC
TGDVVKISPIWKFYAARRIINKPQSYINIDGGGTLACNGTSGMNLIIRDYSSDVVRAFGW
CCCEEEECHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCEEEEEECCCHHHHHHCC
VDSDPSCSWAFDVTPPNSNYTKLYKGTNKVINLRNNGSPFTPGGNYKLTVKGYDKNGKVV
CCCCCCCEEEEECCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCEE
CERSINLKVPNGIANSSAKPIFPGSYTVTAQTVAREYPRSNGAVTGNLKKGQEVGVFAEY
EEEECEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCEEECCCCCCEEEEEEEC
GNWYLVARGTPQWVEKQYLTNK
CCEEEEECCCHHHHHHHHCCCC
>Mature Secondary Structure
MKKKTTILSIFLAVFMALAMNVGQVKAAATGQDIVNYAKQFQGVPYVWGGTSPSGFDCSG
CCCHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHH
FVQYVYRNAAGIELPRDTYGQITKGTPVSQSNLQPGDLVFPHTGHVGIYVGNGQIIHSPQ
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEECCCEEEECCC
TGDVVKISPIWKFYAARRIINKPQSYINIDGGGTLACNGTSGMNLIIRDYSSDVVRAFGW
CCCEEEECHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCEEEEEECCCHHHHHHCC
VDSDPSCSWAFDVTPPNSNYTKLYKGTNKVINLRNNGSPFTPGGNYKLTVKGYDKNGKVV
CCCCCCCEEEEECCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCEE
CERSINLKVPNGIANSSAKPIFPGSYTVTAQTVAREYPRSNGAVTGNLKKGQEVGVFAEY
EEEECEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCEEECCCCCCEEEEEEEC
GNWYLVARGTPQWVEKQYLTNK
CCEEEEECCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]