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The map label for this gene is ycbL [H]

Identifier: 226948202

GI number: 226948202

Start: 1126615

End: 1127379

Strand: Direct

Name: ycbL [H]

Synonym: CLM_1077

Alternate gene names: 226948202

Gene position: 1126615-1127379 (Clockwise)

Preceding gene: 226948201

Following gene: 226948203

Centisome position: 27.11

GC content: 28.89

Gene sequence:

>765_bases
ATGAATGAATGGTTTACCATTGGAAAAATAGATAATACAACTTTTTCAATTAGTGAATATAAGCATTGGGAACAAACTCA
TAGTTATTTATTGATAGGTGAGAAAAAGGCTCTCTTAATTGATACTGGATTAGGTGTAAGTAATATTAAAAATGTTGTAT
TAAGTATTACCAATAAACCAATTCAAGCGGTTACAACCCATGTGCATTGGGATCACATTGGTGGCCATAAAAATTTTGAT
AATATTGCTGTATATGAAGAAGAGAAGAAATGGCTTGAAAGTAAATTCCCGATTTCTTTACAAGCTGTAAAGTCTAATTT
AATGAAAGAGTATTGTTCTTTCCCAAAAAGTTTTAATATTGATGAATATGAAATTTTTCAAGGAAATCCTAATTTAATCT
TATATGATGGGAATATAATTAGCCTAGGAAATAGGGAGATTCAAGTTATACATACACCAGGACATTCACCGGGACATATA
TGTTTGTATGAGAAGGAAAAAGGGTATTTATTTTCTGGTGATTTAATTTATCAGGGAACTCTAGATGCTTTTTATCCTAC
GACAGATCCAATTGATTTTATGCAATCAATTAAGAAAGTGAAAAAATTGAATATAGAAAGAATATTGCCAGCACACTATA
GTTTAAATATCTCATCAAGTCTTATTGATGAGATTGACAAAGGATTTTCTGAAATATATTCATTGGGAAAACTAAAGCAA
GGGAATGGAATATTTAAATTTCAAAATTTTAATATTCACATCTAA

Upstream 100 bases:

>100_bases
TTCCTAATGTTAAAGAAACTACTTTTGCATAATATTTTAAATTATGAAATAGATATTGCTCATTTTAATCATTTAATATA
AGAACTGAGAGGGTGATTGT

Downstream 100 bases:

>100_bases
AAAGGAAATATAAATAATGTAGATAAGTAAGTTTTTAAGAGGAAGAAAAGGTGGCAGCAACGTGATAGCTCCCATAGTAG
ATGCACTAATGTATATGTTA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MNEWFTIGKIDNTTFSISEYKHWEQTHSYLLIGEKKALLIDTGLGVSNIKNVVLSITNKPIQAVTTHVHWDHIGGHKNFD
NIAVYEEEKKWLESKFPISLQAVKSNLMKEYCSFPKSFNIDEYEIFQGNPNLILYDGNIISLGNREIQVIHTPGHSPGHI
CLYEKEKGYLFSGDLIYQGTLDAFYPTTDPIDFMQSIKKVKKLNIERILPAHYSLNISSSLIDEIDKGFSEIYSLGKLKQ
GNGIFKFQNFNIHI

Sequences:

>Translated_254_residues
MNEWFTIGKIDNTTFSISEYKHWEQTHSYLLIGEKKALLIDTGLGVSNIKNVVLSITNKPIQAVTTHVHWDHIGGHKNFD
NIAVYEEEKKWLESKFPISLQAVKSNLMKEYCSFPKSFNIDEYEIFQGNPNLILYDGNIISLGNREIQVIHTPGHSPGHI
CLYEKEKGYLFSGDLIYQGTLDAFYPTTDPIDFMQSIKKVKKLNIERILPAHYSLNISSSLIDEIDKGFSEIYSLGKLKQ
GNGIFKFQNFNIHI
>Mature_254_residues
MNEWFTIGKIDNTTFSISEYKHWEQTHSYLLIGEKKALLIDTGLGVSNIKNVVLSITNKPIQAVTTHVHWDHIGGHKNFD
NIAVYEEEKKWLESKFPISLQAVKSNLMKEYCSFPKSFNIDEYEIFQGNPNLILYDGNIISLGNREIQVIHTPGHSPGHI
CLYEKEKGYLFSGDLIYQGTLDAFYPTTDPIDFMQSIKKVKKLNIERILPAHYSLNISSSLIDEIDKGFSEIYSLGKLKQ
GNGIFKFQNFNIHI

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI42822880, Length=230, Percent_Identity=30.8695652173913, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1787158, Length=188, Percent_Identity=29.2553191489362, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193205216, Length=195, Percent_Identity=31.7948717948718, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17537503, Length=193, Percent_Identity=32.1243523316062, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 29106; Mature: 29106

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEWFTIGKIDNTTFSISEYKHWEQTHSYLLIGEKKALLIDTGLGVSNIKNVVLSITNKP
CCCEEEEEEECCCEEEHHHHHHHHHCCCEEEEECCEEEEEECCCCHHHHHHEEEEECCCC
IQAVTTHVHWDHIGGHKNFDNIAVYEEEKKWLESKFPISLQAVKSNLMKEYCSFPKSFNI
CEEEEEEEEEECCCCCCCCCCEEEEEHHHHHHHHCCCEEHHHHHHHHHHHHHCCCCCCCC
DEYEIFQGNPNLILYDGNIISLGNREIQVIHTPGHSPGHICLYEKEKGYLFSGDLIYQGT
CEEEEEECCCCEEEECCCEEEECCCEEEEEECCCCCCCEEEEEECCCCEEEECCEEEECC
LDAFYPTTDPIDFMQSIKKVKKLNIERILPAHYSLNISSSLIDEIDKGFSEIYSLGKLKQ
CCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEC
GNGIFKFQNFNIHI
CCCEEEEECCEEEC
>Mature Secondary Structure
MNEWFTIGKIDNTTFSISEYKHWEQTHSYLLIGEKKALLIDTGLGVSNIKNVVLSITNKP
CCCEEEEEEECCCEEEHHHHHHHHHCCCEEEEECCEEEEEECCCCHHHHHHEEEEECCCC
IQAVTTHVHWDHIGGHKNFDNIAVYEEEKKWLESKFPISLQAVKSNLMKEYCSFPKSFNI
CEEEEEEEEEECCCCCCCCCCEEEEEHHHHHHHHCCCEEHHHHHHHHHHHHHCCCCCCCC
DEYEIFQGNPNLILYDGNIISLGNREIQVIHTPGHSPGHICLYEKEKGYLFSGDLIYQGT
CEEEEEECCCCEEEECCCEEEECCCEEEEEECCCCCCCEEEEEECCCCEEEECCEEEECC
LDAFYPTTDPIDFMQSIKKVKKLNIERILPAHYSLNISSSLIDEIDKGFSEIYSLGKLKQ
CCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEC
GNGIFKFQNFNIHI
CCCEEEEECCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]